All Relations between dopamine and gfap

Publication Sentence Publish Date Extraction Date Species
Juan Zhuang, Zheng-Jun Pan, Ying Qin, Hui Liang, Wen-Feng Zhang, Ze-Yu Sun, Han-Bo Sh. Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos. Environmental science and pollution research international. 2023-03-04. PMID:36869944. the results showed that bde-47 stimulated the production of dopamine and 5-hydroxytryptamine, but inhibited expression of nestin, gfap, gap43, and psd95 in 24 hpf embryos. 2023-03-04 2023-08-14 zebrafish
Mariam D Oduola-Akande, Ismail O Ishola, Taiwo G Olubodun-Obadun, Adeola J Akande, Olufunmilayo O Adeyem. Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice. Neurotoxicity research. 2023-01-27. PMID:36705862. in addition, mptp-induced nigral dopamine neuron loss (decrease in tyrosine hydroxylase-positive neuron (th)) and neuroinflammation (activation of glial fibrillary acid protein (gfap) and ionized calcium binding adaptor molecule 1 (iba-1)) were ameliorated by gmp administration. 2023-01-27 2023-08-14 mouse
I O Ishola, A K Oloyo, T G Olubodun-Obadun, O D Godswill, S A Omilabu, O O Adeyem. Neuroprotective potential of plant derived parenchymal stem cells extract on environmental and genetic models of Parkinson disease through attenuation of oxidative stress and neuroinflammation. Metabolic brain disease. 2022-11-19. PMID:36401682. mptp-induced expression of microglia (iba-1), astrocytes (glia fibrillary acidic protein; gfap) as well as degeneration of dopamine neurons (tyrosine hydroxylase positive neurons) in the substantia nigra (sn) were reversed by dsc. 2022-11-19 2023-08-14 mouse
Karema Abu-Elfotuh, Somaia A Abdel-Sattar, Ashwaq Najemaldeen Abbas, Yasmen F Mahran, Aliah R Alshanwani, Ahmed Mohsen Elsaid Hamdan, Ahmed M Atwa, Enji Reda, Yasmin M Ahmed, Sameh S Zaghlool, Mahmoud Nour El-Di. The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 155. 2022-10-22. PMID:36271575. all treated groups showed improvement in msg-induced aberrations in brain levels of gsh, il-1β, tnf-α, gfap, glutamate, calcium, dopamine, norepinephrine, wnt3a, β-catenin and bdnf. 2022-10-22 2023-08-14 human
Zhi Jiang, Jie Wang, Gaohui Sun, Meijiang Fen. BDNF-modified human umbilical cord mesenchymal stem cells-derived dopaminergic-like neurons improve rotation behavior of Parkinson's disease rats through neuroprotection and anti-neuroinflammation. Molecular and cellular neurosciences. 2022-10-13. PMID:36228967. results showed that transplantation of bdnf-modified huc-mscs-derived daergic-like neurons improved the apomorphine induced rotation behavior of pd rats, increased the dopamine concentration and the expression of glial fibrillary acidic protein (gfap) and ionized calcium-binding adaptor molecule-1 (iba-1) in the striatum, promoted the expression of tyrosine hydroxylase (th), nuclear receptor-related factor 1 (nurr1), pituitary homeobox 3 (pitx3), bdnf, tyrosine kinase b (trkb), phosphatidylinositol-3-hydroxykinase (pi3k), phosphorylated protein kinase b (p-akt), heat shock protein 60 (hsp60), toll-like receptor 4 (tlr4) and myeloid differentiation factor 88 (myd88) and inhibited the neural apoptosis in the substantia nigra (sn) and striatum. 2022-10-13 2023-08-14 human
Nadire Eser, Mustafa Cicek, Atila Yoldas, Mehmet Demir, Faik Alev Dereso. Caffeic acid phenethyl ester ameliorates imidacloprid-induced acute toxicity in the rat cerebral cortex. Environmental toxicology and pharmacology. 2022-10-03. PMID:36191819. additionally, cape dose-dependently normalized the levels of tnf-α, dopamin, gfap and ngf, and at the highest dose (10mg/kg) also normalized the balance of oxidative parameters (mda, sod, cat, and gsh). 2022-10-03 2023-08-14 rat
Shu-Yun Xiao, Yi-Jie Liu, Wang Lu, Zhong-Wei Sha, Che Xu, Zhi-Hua Yu, Shin-Da Le. Possible Neuropathology of Sleep Disturbance Linking to Alzheimer's Disease: Astrocytic and Microglial Roles. Frontiers in cellular neuroscience. vol 16. 2022-06-27. PMID:35755779. we proposed that possible astrocyte-mediated and microglia-mediated neuropathological changes of sleep disturbances linked to ad, such as astrocytic adenosinergic a1, a2, and a3 regulation; astrocytic dopamine and serotonin; astrocyte-mediated proinflammatory status (tnfα); sleep disturbance-attenuated microglial cx3cr1 and p2y12; microglial iba-1 and astrocytic glial fibrillary acidic protein (gfap); and microglia-mediated proinflammatory status (il-1b, il-6, il-10, and tnfα). 2022-06-27 2023-08-14 Not clear
Omaima I Abdel Hamid, Ayat M Domouky, Yara M El-Fakharan. Molecular evidence of the amelioration of toluene induced encephalopathy by human breast milk mesenchymal stem cells. Scientific reports. vol 12. issue 1. 2022-06-02. PMID:35654991. neurological assessment was evaluated as well as serum levels of glial fibrillary acidic protein (gfap), tumor necrosis factor-alpha (tnf-α), nerve growth factor (ngf), vascular endothelial growth factor (vegf), tissue dopamine and oxidative markers. 2022-06-02 2023-08-14 human
Omaima I Abdel Hamid, Ayat M Domouky, Yara M El-Fakharan. Molecular evidence of the amelioration of toluene induced encephalopathy by human breast milk mesenchymal stem cells. Scientific reports. vol 12. issue 1. 2022-06-02. PMID:35654991. results revealed that toluene caused cerebral injury, as evidenced by a significant increase in serum gfap, tnf-α, malondialdehyde (mda) and nitric oxide (no), a significant decrease in serum ngf, tissue dopamine and oxidative markers, besides, a non-significant change in vegf. 2022-06-02 2023-08-14 human
Xixin Wang, Fangyan Wu, Hongyuan Zou, Yanan Yang, Gaoyang Chen, Kechun Liu, Yun Zhang, Li Li. Neurodevelopmental toxicity of pyrazinamide to larval zebrafish and the restoration after intoxication withdrawing. Journal of applied toxicology : JAT. 2022-02-01. PMID:35102572. moreover, pza-administrated zebrafish showed a decreased dopamine (da) level and downregulated expression of neurodevelopment-related genes, such as shha, mbp, neurog1, and gfap. 2022-02-01 2023-08-13 zebrafish
b' Macarena L Herrera, Romina Deza-Ponzio, Marisa S Ghersi, Emilce A de la Villarmois, Miriam B Virgolini, Mariela F P\\xc3\\xa9rez, Victor A Molina, Mar\\xc3\\xada J Bellini, Claudia B Here\\xc3\\xb1\\xc3\\xb. Early Cognitive Impairment Behind Nigrostriatal Circuit Neurotoxicity: Are Astrocytes Involved? ASN neuro. vol 12. 2021-09-15. PMID:32466659.' we evaluated tyrosine hydroxylase (th) as a dopamine marker, aldehyde dehydrogenase 2 (aldh2), a mitochondria detoxification enzyme and astrocyte glial fibrillar acid protein (gfap) an immunoreactivity marker involved in different areas: cpu, substantia nigra, prefrontal cortex, and hippocampus. 2021-09-15 2023-08-13 Not clear
Akhil Sharma, Viktoriia Bazylianska, Anna Moszczynsk. Parkin-deficient rats are resistant to neurotoxicity of chronic high-dose methamphetamine. Experimental neurology. vol 345. 2021-09-07. PMID:34298012. interestingly, saline-treated pko rats had lower levels of dopamine (da) as well as mitochondrial complex i and ii levels while having increased basal levels of glial fibrillary acidic protein (gfap), a marker of gliosis. 2021-09-07 2023-08-13 rat
Angela M Lee, Mohammad Shahid Mansuri, Rashaun S Wilson, TuKiet T Lam, Angus C Nairn, Marina R Picciott. Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. Frontiers in molecular neuroscience. vol 14. 2021-08-03. PMID:34335180. despite differences by sex, strain, and nicotine exposure parameters, glial fibrillary acidic protein (gfap) and dopamine and camp-regulated phosphoprotein of 32 kda (darpp-32, ppp1r1b) were repeatedly identified as significantly altered proteins, especially in the vta. 2021-08-03 2023-08-13 mouse
Hyeon Joo Ham, In Jun Yeo, Seong Hee Jeon, Jun Hyung Lim, Sung Sik Yoo, Dong Ju Son, Sung-Su Jang, Haksup Lee, Seung-Jin Shin, Sang Bae Han, Jae Suk Yun, Jin Tae Hon. Botulinum Toxin A Ameliorates Neuroinflammation in the MPTP and 6-OHDA-Induced Parkinson's Disease Models. Biomolecules & therapeutics. 2021-07-19. PMID:34078752. we found that bont-a ameliorated mptp and 6-ohda-induced pd progression, reduced acetylcholine release, levels of il-1β, il-6 and tnf-α as well as gfap expression, but enhanced dopamine release and tyrosine hydroxylase expression. 2021-07-19 2023-08-13 Not clear
Rayul Wi, Young Cheul Chung, Byung Kwan Ji. Functional Crosstalk between CB and TRPV1 Receptors Protects Nigrostriatal Dopaminergic Neurons in the MPTP Model of Parkinson's Disease. Journal of immunology research. vol 2020. 2021-07-12. PMID:33062722. mptp induced a significant loss of nigrostriatal dopamine neurons and glial activation in the substantia nigra (sn) and striatum (str) as visualized by tyrosine hydroxylase (th) or macrophage antigen complex-1 (mac-1) or glial fibrillary acidic protein (gfap) immunocytochemistry, respectively. 2021-07-12 2023-08-13 mouse
Jorge A Avila, Roseanna M Zanca, Denis Shor, Nicholas Paleologos, Amber A Alliger, Maria E Figueiredo-Pereira, Peter A Serran. Chronic voluntary oral methamphetamine induces deficits in spatial learning and hippocampal protein kinase Mzeta with enhanced astrogliosis and cyclooxygenase-2 levels. Heliyon. vol 4. issue 2. 2020-10-01. PMID:29560440. compared to controls, the voma paradigm also induced decreases in hippocampal levels of dopamine transporter (dat) and tyrosine hydroxylase (th), as well as increases in dopamine 1 receptor (d1r), glial fibrillary acidic protein (gfap) and cyclooxygenase-2 (cox-2), with a decrease in prostaglandins e2 (pge2) and d2 (pgd2). 2020-10-01 2023-08-13 mouse
Yao-Feng Zhu, Wei-Ping Wang, Xue-Feng Zheng, Zhi Chen, Tao Chen, Zi-Yun Huang, Lin-Ju Jia, Wan-Long Le. Characteristic response of striatal astrocytes to dopamine depletion. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638097. striatal dopamine deprivation increased the number of gfap/s100b and gfap/stat3 double-labeled cells, and increased the protein levels of gfap, s100b, and stat3. 2020-09-28 2023-08-13 rat
Ruchi Sharma, Imke P M Smits, Laura De La Vega, Christopher Lee, Stephanie M Willert. 3D Bioprinting Pluripotent Stem Cell Derived Neural Tissues Using a Novel Fibrin Bioink Containing Drug Releasing Microspheres. Frontiers in bioengineering and biotechnology. vol 8. 2020-09-28. PMID:32117936. these bioprinted neural tissues expressed tuj1 (15 ± 1.3%), the dopamine marker, tyrosine hydroxylase (th) (8 ± 1%) and other glial markers such as glial fibrillary acidic protein (gfap) (15 ± 4%) and oligodendrocyte progenitor marker (o4) (4 ± 1%) after 30 days. 2020-09-28 2023-08-13 human
Giulia Costa, Pier Francesca Porceddu, Marcello Serra, Maria Antonietta Casu, Valentina Schiano, Francesco Napolitano, Annalisa Pinna, Alessandro Usiello, Micaela Morell. Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age. International journal of molecular sciences. vol 20. issue 7. 2019-07-29. PMID:30925704. on this basis, the object of this study was to assess 3,4-methylenedioxymethamphetamine (mdma) effects on microglial (cd11b) and astroglial (gfap) activation and on dopamine neuron degeneration (th) in wild-type (wt) and rhes knockout (ko) male and female mice of different ages. 2019-07-29 2023-08-13 mouse
Shuai Lian, Bin Xu, Di Wang, Lipeng Wang, Wenjie Li, Ruizhi Yao, Hong Ji, Jianfa Wang, Jingru Guo, Shize Li, Huanmin Yan. Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats. Behavioural brain research. vol 359. 2019-04-19. PMID:30423388. to further understand the effects of prenatal cold stress on offspring, we investigated the behavior change; the expression of glucocorticoid receptor (gr), mineralocorticoid receptor (mr), brain-derived neurotrophic factor (bdnf), insulin-like growth factor 1 receptor (igf1r), neuronal nuclei (neun), glial fibrillary acidic protein (gfap), corticotropin-releasing hormone receptor 1 (crhr1), gamma-aminobutyric acid b receptor, 2 (gabab2) proteins in hippocampus; the ratio of cd4/cd8 lymphocyte subsets and the level of norepinephrine (ne), dopamine (da) in the peripheral blood of weaned offspring rats using behavioral tests and biology analysis methods. 2019-04-19 2023-08-13 rat