| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G D Cappon, L L Morford, C V Vorhee. Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response. Brain research. Developmental brain research. vol 103. issue 2. 1998-02-18. PMID:9427479. |
methamphetamine (ma) administration to adult rats results in neurotoxicity characterized by depletion of caudate-putamen (cp) dopamine (da) and serotonin (5-ht) and an accompanying increase in glial fibrillary acidic protein (gfap) content. |
1998-02-18 |
2023-08-12 |
rat |
| R Vento, M Giuliano, M Lauricella, M Carabillò, H Main, E Gerbino, G Tesorier. Differentiation of Y79 cells induced by prolonged exposure to insulin. Molecular and cellular biochemistry. vol 170. issue 1-2. 1997-08-06. PMID:9144331. |
morphological differentiation was accompanied by a marked increase in the content of total protein and in that of tubulin, the major protein constituent of microtubules, a marked increase in the content of specialized protein markers of dopaminergic and cholinergic differentiation (dopamine beta-hydroxylase and choline acetyltransferase activities, respectively); a contemporaneous decrease in the content of glial fibrillary acidic protein (gfap), a specific marker of glial cells, was also observed. |
1997-08-06 |
2023-08-12 |
human |
| R Martin-Fardon, F Sandillon, J Thibault, A Privat, J Vigno. Long-term monitoring of extracellular dopamine concentration in the rat striatum by a repeated microdialysis procedure. Journal of neuroscience methods. vol 72. issue 2. 1997-06-30. PMID:9133576. |
the histological analysis using glial fibrillary acidic protein (gfap), dopamine (da) and tyrosine hydroxylase (th) immunocytochemistry showed a moderate gliosis and a discrete increase of immunoreactivity of catecholaminergic fibres around the probe implantation site. |
1997-06-30 |
2023-08-12 |
rat |
| M Zoli, F Ferraguti, A Frasoldati, G Biagini, L F Agnat. Age-related alterations in tanycytes of the mediobasal hypothalamus of the male rat. Neurobiology of aging. vol 16. issue 1. 1995-05-24. PMID:7723939. |
by means of semiquantitative immunocytochemistry, possible age-related changes in dopamine and cyclic amp-regulated phosphoprotein mr 32 (darpp-32) and glial fibrillary acidic protein (gfap) immunoreactivities (ir) were investigated in tanycytes of the arcuate nucleus. |
1995-05-24 |
2023-08-12 |
rat |
| D B Miller, J P O'Callagha. Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071868. |
levels of striatal dopamine (da) and glial fibrillary acidic protein (gfap) were taken as indicators of neurotoxicity. |
1994-09-28 |
2023-08-12 |
mouse |
| A Bal, T Bachelot, M Savasta, M Manier, J M Verna, A L Benabid, C Feuerstei. Evidence for dopamine D2 receptor mRNA expression by striatal astrocytes in culture: in situ hybridization and polymerase chain reaction studies. Brain research. Molecular brain research. vol 23. issue 3. 1994-09-12. PMID:8057777. |
cells double-labelled for glial fibrillary acidic protein (gfap) immuno-histochemistry and dopamine d2 receptor mrna (ish) provide evidence that striatal but not cerebellar astrocytes express the dopamine d2 gene in vitro. |
1994-09-12 |
2023-08-12 |
rat |
| G Németh, A Cintra, J M Herb, A Ding, M Goldstein, L F Agnati, S Hoyer, K Fux. Changes in striatal dopamine neurohistochemistry and biochemistry after incomplete transient cerebral ischemia in the rat. Experimental brain research. vol 86. issue 3. 1992-02-07. PMID:1662138. |
the ischemia induced striatal lesions were investigated in serial coronal brain sections, stained with cresylviolet or immunostained for dopamine and camp regulated phosphoprotein (darpp-32), for tyrosine hydroxylase (th) and for glial fibrillary acidic protein (gfap) immunoreactivities (ir). |
1992-02-07 |
2023-08-11 |
rat |
| S Y Lu, M T Shipley, A B Norman, P R Sanber. Striatal, ventral mesencephalic and cortical transplants into the intact rat striatum: a neuroanatomical study. Experimental neurology. vol 113. issue 2. 1991-09-13. PMID:1651254. |
here, we have examined the cellular elements of the transplants and their connectivity with the host using histochemistry for cytochrome oxidase (co) and acetylcholinesterase (ache), immunocytochemistry for glial fibrillary acidic protein (gfap), ox42, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), serotonin (5-ht), and cholecystokinin (cck). |
1991-09-13 |
2023-08-11 |
rat |
| D B Miller, J F Reinhard, A J Daniels, J P O'Callagha. Diethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of in vitro 1-methyl-4-phenylpyridinium. Journal of neurochemistry. vol 57. issue 2. 1991-08-21. PMID:1649252. |
pretreatment with ddc potentiated the effect of mptp in striatum and resulted in substantially greater dopamine depletion, as well as a more pronounced elevation in gfap. |
1991-08-21 |
2023-08-11 |
mouse |
| D B Miller, J F Reinhard, A J Daniels, J P O'Callagha. Diethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of in vitro 1-methyl-4-phenylpyridinium. Journal of neurochemistry. vol 57. issue 2. 1991-08-21. PMID:1649252. |
systemically administered mpp+ decreased heart norepinephrine, but did not alter the striatal levels of dopamine or gfap, and pretreatment with ddc did not alter these effects, but did increase lethality. |
1991-08-21 |
2023-08-11 |
mouse |
| J F Reinhard, D B Miller, J P O'Callagha. The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibrillary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury. Neuroscience letters. vol 95. issue 1-3. 1989-03-29. PMID:3265770. |
the neurotoxicant mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), administered to male or female mice, decreased striatal dopamine content and increased the levels of the astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap). |
1989-03-29 |
2023-08-11 |
mouse |
| J F Reinhard, D B Miller, J P O'Callagha. The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibrillary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury. Neuroscience letters. vol 95. issue 1-3. 1989-03-29. PMID:3265770. |
additionally, pargyline pretreatment prevented both the rise in gfap and the decrease in dopamine in striatum. |
1989-03-29 |
2023-08-11 |
mouse |
| J F Reinhard, D B Miller, J P O'Callagha. The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibrillary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury. Neuroscience letters. vol 95. issue 1-3. 1989-03-29. PMID:3265770. |
mptp produced a smaller elevation in gfap levels within a midbrain section of tissue containing the substantia nigra, without significantly decreasing the dopamine content of this structure, suggesting neurotoxic involvement at the level of dopamine perikarya. |
1989-03-29 |
2023-08-11 |
mouse |
| D Semenoff, H K Kimelber. Autoradiography of high affinity uptake of catecholamines by primary astrocyte cultures. Brain research. vol 348. issue 1. 1986-01-22. PMID:3904924. |
uptake of d.l-[3h]norepinephrine ([3h]ne) and [3h]dopamine ([3h]da) by primary astrocyte cultures prepared from neonatal rat brains, which are greater than or equal to 95% glial fibrillary acidic protein (gfap(+)), was studied by measuring accumulation of tritium label, and localizing such uptake at the cellular level by autoradiography. |
1986-01-22 |
2023-08-11 |
rat |