All Relations between dopamine and gaba

Publication Sentence Publish Date Extraction Date Species
Daisuke Tsuboi, Taku Nagai, Junichiro Yoshimoto, Kozo Kaibuch. Neuromodulator regulation and emotions: insights from the crosstalk of cell signaling. Frontiers in molecular neuroscience. vol 17. 2024-03-22. PMID:38516040. neuromodulators such as dopamine and acetylcholine control cognition and emotion by regulating the excitatory/inhibitory balance initiated by glutamate and gaba. 2024-03-22 2024-03-24 Not clear
Wiiliam S Conrad, Lucie Oriol, Lauren Faget, Thomas S Hnask. Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta. bioRxiv : the preprint server for biology. 2024-03-11. PMID:38464250. here, we used fluorescent in situ hybridization in male and female mice to label vta and snc neurons that expressed mrna encoding the canonical vesicular transporters for dopamine, gaba, or glutamate: vesicular monoamine transporter vmat2, vesicular gaba transporter (vgat), and vesicular glutamate transporter (vglut2). 2024-03-11 2024-03-14 mouse
Kazuo Okanari, Hitoshi Teranishi, Ryohei Umeda, Kenshiro Shikano, Masanori Inoue, Toshikatsu Hanada, Kenji Ihara, Reiko Hanad. Behavioral and neurotransmitter changes on antiepileptic drugs treatment in the zebrafish pentylenetetrazol-induced seizure model. Behavioural brain research. 2024-02-25. PMID:38403178. to investigate the effects of aeds such as levetiracetam (lev), carbamazepine (cbz), and fenfluramine (ffr) on key neurotransmitters in the pentylenetetrazol (ptz)-induced seizures in adult zebrafish, we examined the changes in glutamic acid, gamma-aminobutyric acid (gaba), serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), choline, acetylcholine, norepinephrine, dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), and adenosine. 2024-02-25 2024-02-28 zebrafish
Carmen F M van Hooijdonk, Michiel G J Balvers, Marieke van der Pluijm, Charlotte L C Smith, Lieuwe de Haan, Anouk Schrantee, Maqsood Yaqub, Renger F Witkamp, Elsmarieke van de Giessen, Therese A M J van Amelsvoort, Jan Booij, Jean-Paul Selte. Endocannabinoid levels in plasma and neurotransmitters in the brain: a preliminary report on patients with a psychotic disorder and healthy individuals. Psychological medicine. 2024-02-23. PMID:38389452. consequently, we investigated in patients with ssd and healthy controls (hc) the relations between (1) plasma concentrations of two prototypical endocannabinoids (n-arachidonoylethanolamine [anandamide] and 2-arachidonoylglycerol [2-ag]) and (2) striatal dopamine synthesis capacity (dsc), and glutamate and y-aminobutyric acid (gaba) levels in the anterior cingulate cortex (acc). 2024-02-23 2024-02-25 Not clear
Mani Surya Kumar Palepu, Siva Nageswara Rao Gajula, Malleshwari K, Rajesh Sonti, Manoj P Dandeka. SCFAs Supplementation Rescues Anxiety- and Depression-like Phenotypes Generated by Fecal Engraftment of Treatment-Resistant Depression Rats. ACS chemical neuroscience. 2024-02-21. PMID:38382546. administration of scfas (acetate, propionate, and butyrate at 67.5, 25, and 40 mm, respectively) for 7 days exerted robust antidepressant and antianxiety effects by restoring the levels of scfas in plasma and fecal samples, and proinflammatory cytokines (tnf-α and il-6), serotonin, gaba, norepinephrine, and dopamine in the hippocampus and/or frontal cortex of trd and trd-fmt animals. 2024-02-21 2024-02-24 rat
Nan Song, Zhenhong Liu, Yan Gao, Shanshan Lu, Shenglian Yang, Chao Yua. NAc-DBS corrects depression-like behaviors in CUMS mouse model via disinhibition of DA neurons in the VTA. Molecular psychiatry. 2024-02-16. PMID:38361128. moreover, even a single trial nac-dbs led to the elevation of the γ-aminobutyric acid (gaba) neurotransmitter, accompanied by the increase in dopamine (da) neuron activity in the vta. 2024-02-16 2024-02-18 mouse
Michele Petrella, Anna Maria Borruto, Lorenzo Curti, Domi, Esi Domi, Li Xu, Estelle Barbier, Alice Ilari, Markus Heilig, Friedbert Weiss, Guido Mannaioni, Alessio Masi, Roberto Ciccociopp. Pharmacological blockage of NOP receptors decreases ventral tegmental area dopamine neuronal activity through GABA Neuropharmacology. 2024-02-16. PMID:38364970. pharmacological blockage of nop receptors decreases ventral tegmental area dopamine neuronal activity through gaba the nociceptin/orphanin fq (n/ofq) peptide and its receptor nop are highly expressed within several regions of the mesolimbic system, including the ventral tegmental area (vta). 2024-02-16 2024-02-19 rat
Amjad Mhanna, Nafiza Martini, Ghefar Hmaydoosh, George Hamwi, Mulham Jarjanazi, Ghaith Zaifah, Reem Kazzazo, Aya Haji Mohamad, Zuheir Alshehab. The correlation between gut microbiota and both neurotransmitters and mental disorders: A narrative review. Medicine. vol 103. issue 5. 2024-02-02. PMID:38306525. this review aims to summarize the modulation role of the gut microbiota in 4 prominent neurotransmitters (tryptophan and serotonergic system, dopamine, gamma-aminobutyric acid, and glutamate), as well as its association with 4 psychiatric disorders (schizophrenia, depression, anxiety disorders, and autism spectrum disorder). 2024-02-02 2024-02-05 Not clear
M Flavia Barbano, Shiliang Zhang, Emma Chen, Orlando Espinoza, Uzma Mohammad, Yocasta Alvarez-Bagnarol, Bing Liu, Suyun Hahn, Marisela Morale. Lateral hypothalamic glutamatergic inputs to VTA glutamatergic neurons mediate prioritization of innate defensive behavior over feeding. Nature communications. vol 15. issue 1. 2024-01-09. PMID:38195566. by vta specific neuronal ablation, we established that predator-induced decreases in feeding were mediated by vta-glutamatergic neurons but not by dopamine or gaba neurons. 2024-01-09 2024-01-13 mouse
Nikolas Bergum, Casey-Tyler Berezin, Jozsef Vig. Dopamine enhances GABA bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168350. dopamine enhances gaba neuromodulation in the retina is crucial for effective processing of retinal signal at different levels of illuminance. 2024-01-03 2024-01-06 Not clear
Nikolas Bergum, Casey-Tyler Berezin, Jozsef Vig. Dopamine enhances GABA bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168350. although µ-opioid receptor (mor) activation had no effect on γ-aminobutyric acid (gaba) currents, dopamine (via the d1r) amplified gabaergic currents in a subset of iprgcs. 2024-01-03 2024-01-06 Not clear
Oliver D Howes, Bernard R Bukala, Katherine Bec. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nature reviews. Neurology. 2023-12-19. PMID:38110704. this evidence demonstrates regionally specific neurotransmitter alterations, including higher glutamate and dopamine measures in the basal ganglia, and lower glutamate, dopamine and γ-aminobutyric acid (gaba) levels in cortical regions, particularly the frontal cortex, relative to healthy individuals. 2023-12-19 2023-12-21 Not clear
Laura Kubens, Ann-Kathrin Weishaupt, Vivien Michaelis, Isabelle Rohn, Fabian Mohr, Julia Bornhors. Exposure to the environmentally relevant fungicide Maneb: Studying toxicity in the soil nematode Caenorhabditis elegans. Environment international. vol 183. 2023-12-10. PMID:38071851. nevertheless, an alteration in the neurotransmitter homeostasis of dopamine, acetylcholine, and gamma-butyric acid (gaba) was observed as well as morphological changes in the dopaminergic neurons upon maneb exposure, which underlines the assumption of the neurotoxic potential of maneb. 2023-12-10 2023-12-17 caenorhabditis_elegans
Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, Mikhail Y Kochukov, Benjamin D W Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R Arenkie. Co-transmitting interneurons in the mouse olfactory bulb regulate olfactory detection and discrimination. Cell reports. vol 42. issue 12. 2023-11-19. PMID:37980561. superficial short-axon cells in the olfactory bulb release both dopamine and γ-aminobutyric acid (gaba), yet the specific targets of these neurotransmitters and their respective roles in olfaction have remained unknown. 2023-11-19 2023-11-29 mouse
Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, Mikhail Y Kochukov, Benjamin D W Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R Arenkie. Co-transmitting interneurons in the mouse olfactory bulb regulate olfactory detection and discrimination. Cell reports. vol 42. issue 12. 2023-11-19. PMID:37980561. here, we implement intersectional genetics in mice to selectively block gaba or dopamine release from superficial short-axon cells to identify their distinct cellular targets, impact on circuit function, and behavioral contribution of each neurotransmitter toward olfactory behaviors. 2023-11-19 2023-11-29 mouse
Emily M Black, Shanna B Samels, Wei Xu, Jessica R Barson, Caroline E Bass, Sandhya Kortagere, Rodrigo A Españ. Hypocretin / Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and Motivation for Cocaine. Addiction neuroscience. vol 7. 2023-10-20. PMID:37854172. hypocretin / orexin receptor 1 knockdown in gaba or dopamine neurons in the ventral tegmental area differentially impact mesolimbic dopamine and motivation for cocaine. 2023-10-20 2023-11-08 rat
Georgia E Hodes, Debra Bangasser, Ioannis Sotiropoulos, Nikolaos Kokras, Christina Dall. Sex Differences in Stress Response: Classical Mechanisms and Beyond. Current neuropharmacology. 2023-10-19. PMID:37855285. then, we present sex differences in neurotransmitter levels, such as serotonin, dopamine, glutamate and gaba, as well as indices of neurodegeneration, such as amyloid β and tau. 2023-10-19 2023-11-08 Not clear
Lianwei Mu, Xiaojie Liu, Hao Yu, Casey R Vickstrom, Vladislav Friedman, Thomas J Kelly, Ying Hu, Wantang Su, Shuai Liu, John R Mantsch, Qing-Song Li. cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement. Molecular psychiatry. 2023-10-16. PMID:37845497. we report that rat vta dopamine neurons predominantly express hcn3-4 mrna, while vta gaba neurons express hcn1-4 mrna. 2023-10-16 2023-11-08 rat
Hyun-Jin Kim, Byungjae Hwang, Maria Reva, Jieun Lee, Byeong Eun Lee, Youngeun Lee, Eun Jeong Cho, Minseok Jeong, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Jung-Hoon Park, Jae-Ick Ki. GABAergic-like dopamine synapses in the brain. Cell reports. vol 42. issue 10. 2023-10-11. PMID:37819757. here, we show that dopamine transmission is strongly correlated with gaba co-transmission across the brain and dopamine synapses are structured and function like gabaergic synapses with marked regional heterogeneity. 2023-10-11 2023-10-15 Not clear
Hyun-Jin Kim, Byungjae Hwang, Maria Reva, Jieun Lee, Byeong Eun Lee, Youngeun Lee, Eun Jeong Cho, Minseok Jeong, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Jung-Hoon Park, Jae-Ick Ki. GABAergic-like dopamine synapses in the brain. Cell reports. vol 42. issue 10. 2023-10-11. PMID:37819757. interestingly, the knockdown of neuroligin-2, a key postsynaptic protein at gabaergic synapses, unexpectedly does not weaken gaba co-transmission but instead facilitates it at dopamine synapses in the striatal neurons. 2023-10-11 2023-10-15 Not clear