| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacob L Nudelman, James A Walt. Acute and Lifetime Stress and Psychotic Illness: The Roles of Reward and Salience Networks. Journal of psychiatry and brain science. vol 7. issue 6. 2023-02-06. PMID:36741029. |
we recount how the reward and salience networks of the brain, together with inputs from the dopamine and serotonin neurotransmitter systems, are implicated in both affective reactivity to stress and the symptoms of psychosis, likely mediate the effects of stress and trauma on the symptoms of psychosis and could serve as targets for interventions. |
2023-02-06 |
2023-08-14 |
Not clear |
| Shrujna Patel, Brooke A Keating, Russell C Dal. Anti-inflammatory properties of commonly used psychiatric drugs. Frontiers in neuroscience. vol 16. 2023-01-27. PMID:36704001. |
instead, therapeutics are focused on symptoms and syndromes, largely driven by neurotransmitter hypotheses, such as serotonin or dopamine hypotheses of depression. |
2023-01-27 |
2023-08-14 |
human |
| Ashish Tiwari, Sidharth Walia, Shradha Sharma, Sunidhi Chauhan, Manish Kumar, Trilochan Gadly, Jaspreet Kaur Randhaw. High quantum yield carbon dots and nitrogen-doped carbon dots as fluorescent probes for spectroscopic dopamine detection in human serum. Journal of materials chemistry. B. 2023-01-04. PMID:36597935. |
in this study, one-step hydrothermally synthesised carbon dots (cd) and nitrogen doped carbon dots (ncd) with high quantum yields of 54.29% and 89.82%, respectively, were investigated and demonstrated to be a reliable, cost-effective, and naked-eye fluorescent probe for the detection of dopamine, a neurotransmitter, in human serum fluids. |
2023-01-04 |
2023-08-14 |
human |
| Xiaoyan Ding, Mengdie Yang, Ning Wu, Jin Li, Rui Son. Blockade of dopamine D3 receptor in ventral tegmental area attenuating contextual fear memory. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592493. |
at last, using fiber photometry system, we found that microinjection of yqa14 in vta promoted the dopamine neurotransmitter release in the basolateral amygdala (bla), and pre-training yqa14 infusion in vta lowered the increase of dopamine (da) in bla induced by shock during the training session or by context during the retrieval session. |
2023-01-02 |
2023-08-14 |
Not clear |
| Guowang Cheng, Zhongjun Li, Yujing Liu, Rui Ma, Xiaojia Chen, Wen Liu, Yafang Song, Yuan Zhang, Guangtao Yu, Zhenfeng Wu, Tongkai Che. "Swiss Army Knife" black phosphorus-based nanodelivery platform for synergistic antiparkinsonian therapy via remodeling the brain microenvironment. Journal of controlled release : official journal of the Controlled Release Society. 2022-12-16. PMID:36526020. |
in pd brains, the biological effects of bp and mt resulted in the removal of excess ros, effective reduction of neuroinflammation, decreased aggregation of pathogenic proteins, and improved neurotransmitter delivery, eventually restoring dopamine levels in the striatum. |
2022-12-16 |
2023-08-14 |
Not clear |
| Ciara Frances Pugh, Brian Thomas DeVree, Solveig Gaarde Schmidt, Claus Juul Lolan. Pharmacological Characterization of Purified Full-Length Dopamine Transporter from Cells. vol 11. issue 23. 2022-12-11. PMID:36497070. |
pharmacological characterization of purified full-length dopamine transporter from the dopamine transporter (dat) is a member of the neurotransmitter:sodium symporter (nss) family, mediating the sodium-driven reuptake of dopamine from the extracellular space thereby terminating dopaminergic neurotransmission. |
2022-12-11 |
2023-08-14 |
Not clear |
| Nace Mikus, Sebastian Korb, Claudia Massaccesi, Christian Gausterer, Irene Graf, Matthäus Willeit, Christoph Eisenegger, Claus Lamm, Giorgia Silani, Christoph Mathy. Effects of dopamine D2/3 and opioid receptor antagonism on the trade-off between model-based and model-free behaviour in healthy volunteers. eLife. vol 11. 2022-12-05. PMID:36468832. |
drugs that target opioid and dopamine receptors are notorious for inducing maladaptive habitual drug consumption; yet, how the opioidergic and dopaminergic neurotransmitter systems contribute to the arbitration between habitual and goal-directed behaviour is poorly understood. |
2022-12-05 |
2023-08-14 |
human |
| Bina Lee, Ingabire Ines, Jihyun Je, Eun Jung Park, Hyemin Seong, Min Gi Jo, Hwajin Kim, Seon-Hee Kim, Seong Jae Kim, Hye Jung Kim, Minkyeong Kim, Sang Won Park, Seung Pil Yu. Effect of Renal Ischemia Reperfusion on Brain Neuroinflammation. Biomedicines. vol 10. issue 11. 2022-11-26. PMID:36428560. |
the striatum and ventral midbrain, known to control overall movement, secrete the neurotransmitter dopamine. |
2022-11-26 |
2023-08-14 |
Not clear |
| Giulia Tomagra, Giulia Peroni, Pietro Aprà, Valentina Bonino, Matteo Campostrini, Valentina Carabelli, Cecilia Collà Ruvolo, Alessandro Lo Giudice, Laura Guidorzi, Lorenzo Mino, Paolo Olivero, Luca Pacher, Fabio Picariello, Alessandro Re, Valentino Rigato, Marco Truccato, Veronica Varzi, Ettore Vittone, Federico Picoll. Diamond-based sensors for in vitro cellular radiobiology: Simultaneous detection of cell exocytic activity and ionizing radiation. Biosensors & bioelectronics. vol 220. 2022-11-14. PMID:36375258. |
the devices were functionally characterized by testing both the above-mentioned detection schemes, namely: amperometric measurements of neurotransmitter release from excitable cells (such as dopamine or adrenaline) and dosimetric evaluation using different ionizing particles (alpha particle and x-ray photons). |
2022-11-14 |
2023-08-14 |
Not clear |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Yeon-Ju Lee, Hye-Yoon Jeon, Ah-Jun Lee, Minsoo Kim, Kwon-Soo H. Dopamine ameliorates hyperglycemic memory-induced microvascular dysfunction in diabetic retinopathy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 12. 2022-11-04. PMID:36331561. |
dopamine is a neurotransmitter that mediates visual function in the retina and diabetic retinopathy (dr) is the most common microvascular complication of diabetes and the leading cause of blindness; however, the role of dopamine in retinal vascular dysfunction in dr remains unclear. |
2022-11-04 |
2023-08-14 |
mouse |
| Wu Jiang, Fan He, Guoming Ding, Junsong W. Dopamine inhibits pyroptosis and attenuates secondary damage after spinal cord injury in female mice. Neuroscience letters. 2022-10-28. PMID:36307053. |
dopamine is a neurotransmitter that also regulates nucleotide-binding oligomerization domain-like receptor 3 (nlrp3) inflammasome-dependent neuroinflammation. |
2022-10-28 |
2023-08-14 |
mouse |
| Lavita Nuraviana Rizalputri, Isa Anshori, Murni Handayani, Gilang Gumilar, Ni Luh Wulan Septiani, Yeni Wahyuni Hartati, Muhammad Sjahrul Annas, Agnes Purwidyantri, Briliant Adhi Prabowo, Brian Yuliart. Facile and controllable synthesis of monodisperse gold nanoparticle bipyramid for electrochemical dopamine sensor. Nanotechnology. 2022-10-27. PMID:36301678. |
carried out for the detection of dopamine (da), a neurotransmitter frequently linked to the risk of parkinson's, alzheimer's, and huntington's diseases, the aunb decorated-carbon electrode shows outstanding electrocatalytic activity that improves sensing performance, including high sensitivity, low detection limit, wide dynamic range, high selectivity against different analytes, such as ascorbic acid (aa), uric acid (ua) and urea, and excellent reproducibility. |
2022-10-27 |
2023-08-14 |
Not clear |
| Christoph Koch, Christian Baeuchl, Franka Glöckner, Philipp Riedel, Johannes Petzold, Michael Smolka, Shu-Chen Li, Nicolas W Schuc. L-DOPA enhances neural direction signals in younger and older adults. NeuroImage. 2022-10-15. PMID:36243268. |
using a double-blind cross-over l-dopa/placebo intervention design, we find causal evidence that the neurotransmitter dopamine impacts the fidelity of direction selective neural representations in the human hippocampus and retrosplenial cortex. |
2022-10-15 |
2023-08-14 |
human |
| Armando G Salinas, Jacob A Nadel, Yolanda Mateo, Thanh Huynh, Shana M Augustin, Karel Pacak, David M Lovinge. Chronic Ethanol Consumption Alters Presynaptic Regulation of Dorsal Striatal Dopamine Release in C57BL/6J Mice. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232321. |
dopamine has been implicated in neural and behavioral processes involved in reward and reinforcement and is a critical neurotransmitter in aud. |
2022-10-14 |
2023-08-14 |
mouse |
| Dmitry Troshev, Alyona Bannikova, Victor Blokhin, Anna Kolacheva, Tatiana Pronina, Michael Ugrumo. Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232359. |
in this study, it was shown that in transgenic mice expressing green fluorescent protein (gfp) under the tyrosine hydroxylase (th) gene promoter, (i) there are striatal neurons expressing only th, only aromatic l-amino acid decarboxylase (aadc), or both enzymes of dopamine synthesis; (ii) striatal neurons expressing dopamine-synthesizing enzymes are not dopaminergic since they lack a dopamine transporter; (iii) monoenzymatic neurons expressing individual complementary dopamine-synthesizing enzymes produce this neurotransmitter in cooperation; (iv) striatal nerve fibers containing only th, only aadc, or both enzymes project into the lateral ventricles, providing delivery pathways for l-3,4-dihydroxyphenylalanine and dopamine to the cerebrospinal fluid; and (v) striatal gfp neurons express receptor genes for various signaling molecules, i.e., classical neurotransmitters, neuropeptides, and steroids, indicating fine regulation of these neurons. |
2022-10-14 |
2023-08-14 |
mouse |
| Md Mominur Rahman, Md Rezaul Islam, Sadia Afsana Mim, Nasrin Sultana, Dinesh Kumar Chellappan, Kamal Dua, Mohammad Amjad Kamal, Rohit Sharma, Talha Bin Emra. Insights into the Promising Prospect of G Protein and GPCR-Mediated Signaling in Neuropathophysiology and Its Therapeutic Regulation. Oxidative medicine and cellular longevity. vol 2022. 2022-10-03. PMID:36187336. |
dopamine, an important neurotransmitter, is primarily involved in the pathophysiology of several cns disorders; for instance, bipolar disorder, schizophrenia, parkinson's disease, and adhd. |
2022-10-03 |
2023-08-14 |
Not clear |
| Silvia Hoirisch-Clapauc. The Fibrinolytic System in Peripartum Depression. Seminars in thrombosis and hemostasis. 2022-09-16. PMID:36113504. |
tissue plasminogen activator and plasmin also mediate the release of dopamine, a neurotransmitter implicated in motivation and reward. |
2022-09-16 |
2023-08-14 |
Not clear |
| Shubhangini Tiwari, Parul Gupta, Abhishek Singh, Swati Chaturvedi, M Wahajuddin, Amit Mishra, Sarika Sing. 4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation. Neurochemical research. 2022-08-03. PMID:35922743. |
first, we observed the significant protective effects of 4pba on pd specific neuromuscular coordination, level of tyrosine hydroxylase, α-synuclein level and neurotransmitter dopamine in both substantia nigra and striatal regions of the experimental rat model of pd. |
2022-08-03 |
2023-08-14 |
rat |
| Shima Kouhnavardi, Alev Ecevitoglu, Vladimir Dragačević, Fabrizio Sanna, Edgar Arias-Sandoval, Predrag Kalaba, Michael Kirchhofer, Jana Lubec, Marco Niello, Marion Holy, Martin Zehl, Matthias Pillwein, Judith Wackerlig, Rita Murau, Andrea Mohrmann, Kathryn R Beard, Harald H Sitte, Ernst Urban, Claudia Sagheddu, Marco Pistis, Roberto Plasenzotti, John D Salamone, Thierry Langer, Gert Lubec, Francisco J Monj. A Novel and Selective Dopamine Transporter Inhibitor, Biomolecules. vol 12. issue 7. 2022-07-27. PMID:35883437. |
a novel and selective dopamine transporter inhibitor, dopamine (da), the most abundant human brain catecholaminergic neurotransmitter, modulates key behavioral and neurological processes in young and senescent brains, including motricity, sleep, attention, emotion, learning and memory, and social and reward-seeking behaviors. |
2022-07-27 |
2023-08-14 |
human |