| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sixiang Chen, Xingyu Huang, Xintong Zhang, Chan Li, Yuan-Wei Zhan. A Conserved Intramolecular Ion-Pair Plays a Critical but Divergent Role in Regulation of Dimerization and Transport Function among the Monoamine Transporters. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612840. |
the monoamine transporters, including the serotonin transporter (sert), dopamine transporter (dat), and norepinephrine transporter (net), are the therapeutic targets for the treatment of many neuropsychiatric disorders. |
2024-04-13 |
2024-04-15 |
Not clear |
| Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth, Modi Niharika, Negi Preeya, Islam Rezau. Molecular Docking, MM-GBSA, and Molecular Dynamics Approach: 5-MeO-DMT Analogues as Potential Antidepressants. Archives of Razi Institute. vol 78. issue 5. 2024-04-09. PMID:38590677. |
according to the monoamine-deficiency hypothesis, the underlying pathophysiology of depression is a deficiency of some neurotransmitters (serotonin, norepinephrine, or dopamine) in the central nervous system. |
2024-04-09 |
2024-04-11 |
Not clear |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. |
2024-04-08 |
2024-04-11 |
rat |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Alexis N Jameson, Justin K Siemann, Carrie A Grueter, BradA Grueter, Douglas G McMaho. Effects of age and sex on photoperiod modulation of nucleus accumbens monoamine content and release in adolescence and adulthood. Neurobiology of sleep and circadian rhythms. vol 16. 2024-04-08. PMID:38585223. |
using periadolescent and young adult male and female mice, here we assessed photoperiod's effect on serotonin and dopamine tissue content in the nucleus accumbens core, as well as on accumbal synaptic dopamine release and uptake. |
2024-04-08 |
2024-04-10 |
mouse |
| Alexis N Jameson, Justin K Siemann, Carrie A Grueter, BradA Grueter, Douglas G McMaho. Effects of age and sex on photoperiod modulation of nucleus accumbens monoamine content and release in adolescence and adulthood. Neurobiology of sleep and circadian rhythms. vol 16. 2024-04-08. PMID:38585223. |
we found greater serotonin and dopamine tissue content in the nucleus accumbens from young adult mice raised in a short winter-like photoperiod. |
2024-04-08 |
2024-04-10 |
mouse |
| Zhiwei Huang, Junhao Wu, Yihui Guan, Yumei Wei, Fang Xie, Yifeng She. PET/CT study of dopamine transporter (DAT) binding with the triple reuptake inhibitor toludesvenlafaxine in rats and humans. European journal of nuclear medicine and molecular imaging. 2024-04-08. PMID:38587645. |
despite the in vitro evidence that toludesvenlafaxine inhibits the reuptake of serotonin (5-ht), norepinephrine (ne) and dopamine (da), there is no in vivo evidence that toludesvenlafaxine binds to dat and increases da level, a mechanism thought to contribute to its favorable clinical performance. |
2024-04-08 |
2024-04-10 |
rat |
| Joseph S Lonstein, Taryn A Meinhardt, Pavlina Pavlidi, Nikos Kokras, Christina Dalla, Thierry D Charlier, Jodi L Pawlusk. Maternal probiotic Lactocaseibacillus rhamnosus HN001 treatment alters postpartum anxiety, cortical monoamines, and the gut microbiome. Psychoneuroendocrinology. vol 165. 2024-04-03. PMID:38569396. |
the results revealed that, even without pregnancy stress, hn001 reduced postpartum anxiety-related behavior, increased variability in behavioral fragmentation when dams interacted with pups, increased time away from pups, and decreased prefrontal cortex norepinephrine (ne), dopamine (da) and serotonin (5-ht). |
2024-04-03 |
2024-04-06 |
rat |
| Linlin Zhang, Yuanyuan Chen, Yongzhao Fan, Lin Sh. Treadmill exercise pretreatment ameliorated structural synaptic plasticity impairments of medial prefrontal cortex in vascular dementia rat and improved recognition memory. Scientific reports. vol 14. issue 1. 2024-03-27. PMID:38531892. |
finally, microdialysis coupled with high-performance liquid chromatography was used to assess the levels of 5-ht and dopamine in the medial prefrontal cortex. |
2024-03-27 |
2024-03-29 |
rat |
| Linlin Zhang, Yuanyuan Chen, Yongzhao Fan, Lin Sh. Treadmill exercise pretreatment ameliorated structural synaptic plasticity impairments of medial prefrontal cortex in vascular dementia rat and improved recognition memory. Scientific reports. vol 14. issue 1. 2024-03-27. PMID:38531892. |
lastly, the levels of dopamine and 5-ht in the medial prefrontal cortex of rats in the vd group was significantly lower compared to the con group (p < 0.01), and treadmill exercise was shown to significantly increased the levels of dopamine and 5-ht in the vd rats (p < 0.05). |
2024-03-27 |
2024-03-29 |
rat |
| Annalisa Chiavaroli, Simonetta Cristina Di Simone, Alessandra Acquaviva, Nilofar Nilofar, Maria Loreta Libero, Luigi Brunetti, Lucia Recinella, Sheila Leone, Giustino Orlando, Gokhan Zengin, Maura Di Vito, Luigi Menghini, Claudio Ferrant. Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus. Chemistry & biodiversity. 2024-03-25. PMID:38527165. |
the formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide y (npy), and orexin a. |
2024-03-25 |
2024-03-28 |
mouse |
| Eman Ali, Fakhar Latif, Yusra Mashkoor, Ayesha Sheikh, Amna Iqbal, Rabia Owais, Jawad Ahmed, Sadiq Naveed, Abdul Moeed, Irfan Ullah, Sanila Mugha. Role of adjunctive cariprazine for treatment-resistant depression in patients with major depressive disorder: A systematic review and meta-analysis of randomized controlled trials. Asian journal of psychiatry. vol 95. 2024-03-21. PMID:38513509. |
cariprazine is an orally active dopamine d3-preferring d3/d2 receptor and serotonin 5-ht1a receptor partial agonist, being considered as a treatment for refractory mdd. |
2024-03-21 |
2024-03-24 |
Not clear |
| Maj Vinberg, Roger S McIntyre, Annamaria Giraldi, Klara Coell. Struggling Can Also Show on the Inside: Current Knowledge of the Impact of Childhood Maltreatment on Biomarkers in Mood Disorderss. Neuropsychiatric disease and treatment. vol 20. 2024-03-18. PMID:38496323. |
neurotransmitters, such as serotonin, dopamine, norepinephrine, and hormones (eg the stress hormone cortisol), play a crucial role in regulating mood and emotion. |
2024-03-18 |
2024-03-20 |
Not clear |
| Małgorzata Łupina, Agnieszka Wąsik, Irena Baranowska-Bosiacka, Maciej Tarnowski, Tymoteusz Słowik, Piotr Listos, Jolanta Kotlińska, Danuta Kosik-Bogacka, Izabela Gutowska, Joanna Listo. Acute and Chronic Exposure to Linagliptin, a Selective Inhibitor of Dipeptidyl Peptidase-4 (DPP-4), Has an Effect on Dopamine, Serotonin and Noradrenaline Level in the Striatum and Hippocampus of Rats. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474255. |
acute and chronic exposure to linagliptin, a selective inhibitor of dipeptidyl peptidase-4 (dpp-4), has an effect on dopamine, serotonin and noradrenaline level in the striatum and hippocampus of rats. |
2024-03-13 |
2024-03-15 |
rat |
| Flóra Gölöncsér, Mária Baranyi, Pál Tod, Fruzsina Maácz, Beáta Sperlág. P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β. iScience. vol 27. issue 3. 2024-03-06. PMID:38444608. |
amph increased il-10, tnf-α, and tbars levels, but did not influence bdnf levels, serotonin, dopamine, and noradrenaline content in brain tissues in either genotypes. |
2024-03-06 |
2024-03-08 |
mouse |
| Dileshwar Kumar, Sukesh Narayan Sinha, Balaji Goud. Novel LC-MS/MS Method for Simultaneous Determination of Monoamine Neurotransmitters and Metabolites in Human Samples. Journal of the American Society for Mass Spectrometry. 2024-03-06. PMID:38447073. |
for the simultaneous determination of monoamine neurotransmitters (nts) like dopamine, serotonin, noradrenaline, and epinephrine, and their metabolites (metanephrine, normetanephrine, 3-methoxytyramine, vanillylmandelic acid, 3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindoleacetic acid), a robust liquid chromatography method coupled with tandem mass spectrometry (lc-ms/ms) was introduced as the analytical method. |
2024-03-06 |
2024-03-09 |
human |
| Yu Dai, Chenchen Zhang, Lingrui Zhang, Chao Wen, Hongya Li, Tianmin Zh. Genetic polymorphism in HTR2A rs6313 is associated with internet addiction disorder. Frontiers in psychiatry. vol 15. 2024-02-29. PMID:38419907. |
previous studies have indicated that individuals with iad may exhibit altered levels of serotonin and dopamine, which are known to play crucial roles in depression, anxiety, impulsivity, and addiction. |
2024-02-29 |
2024-03-02 |
Not clear |
| Judith R Homberg, Paola Brivio, Corina U Greven, Francesca Calabres. Individuals being high in their sensitivity to the environment: are sensitive period changes in play? Neuroscience and biobehavioral reviews. 2024-02-28. PMID:38417743. |
key genes that contribute to individual differences in environmental sensitivity are the serotonin transporter, dopamine d4 receptor and brain-derived neurotrophic factor genes. |
2024-02-28 |
2024-03-02 |
Not clear |
| Seth R Batten, Dan Bang, Brian H Kopell, Arianna N Davis, Matthew Heflin, Qixiu Fu, Ofer Perl, Kimia Ziafat, Alice Hashemi, Ignacio Saez, Leonardo S Barbosa, Thomas Twomey, Terry Lohrenz, Jason P White, Peter Dayan, Alexander W Charney, Martijn Figee, Helen S Mayberg, Kenneth T Kishida, Xiaosi Gu, P Read Montagu. Dopamine and serotonin in human substantia nigra track social context and value signals during economic exchange. Nature human behaviour. 2024-02-27. PMID:38409356. |
dopamine and serotonin in human substantia nigra track social context and value signals during economic exchange. |
2024-02-27 |
2024-03-02 |
human |
| Seth R Batten, Dan Bang, Brian H Kopell, Arianna N Davis, Matthew Heflin, Qixiu Fu, Ofer Perl, Kimia Ziafat, Alice Hashemi, Ignacio Saez, Leonardo S Barbosa, Thomas Twomey, Terry Lohrenz, Jason P White, Peter Dayan, Alexander W Charney, Martijn Figee, Helen S Mayberg, Kenneth T Kishida, Xiaosi Gu, P Read Montagu. Dopamine and serotonin in human substantia nigra track social context and value signals during economic exchange. Nature human behaviour. 2024-02-27. PMID:38409356. |
here, we obtained subsecond estimates of dopamine and serotonin from human substantia nigra pars reticulata during the ultimatum game. |
2024-02-27 |
2024-03-02 |
human |