| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
the old sw\xe2\x80\x89+\xe2\x80\x89la-cnps group increased (improved) spinal cord gaba (p\xe2\x80\x89=\xe2\x80\x890.0187), bdnf (p\xe2\x80\x89=\xe2\x80\x890.0003), trkb (p\xe2\x80\x89<\xe2\x80\x890.0001) gene expression, decreased autophagy marker lc3 protein (p\xe2\x80\x89<\xe2\x80\x890.0001), nerve atrophy and jumping/licking latency (p\xe2\x80\x89<\xe2\x80\x890.0001), improved sciatic functional index score and total oxidant status/total antioxidant capacity compared to the old group (p\xe2\x80\x89<\xe2\x80\x890.0001). |
2023-03-04 |
2023-03-06 |
rat |
| Aya A Zayed, Mae M Seleem, Hebatallah A Darwish, Amira A Shahee. Role of long noncoding RNAs; BDNF-AS and 17A and their relation to GABAergic dysfunction in Egyptian epileptic patients. Metabolic brain disease vol issue 2023 36807083 |
this study investigated the expression levels of lncrnas; bdnf-as and 17a in the sera of egyptian patients with idiopathic generalized and symptomatic focal epilepsy and correlated their levels with brain-derived neurotrophic factor (bdnf), phosphorylated camp reaction element -binding protein (p-creb), gamma- aminobutyric acid (gaba) and glutamate, to underline their related molecular mechanism. |
2023-02-22 |
2023-03-06 |
Not clear |
| Aya A Zayed, Mae M Seleem, Hebatallah A Darwish, Amira A Shahee. Role of long noncoding RNAs; BDNF-AS and 17A and their relation to GABAergic dysfunction in Egyptian epileptic patients. Metabolic brain disease vol issue 2023 36807083 |
epileptic patients showed significantly lower levels of bdnf, p-creb, gaba along with significant increase of glutamate levels and glutamate/ gaba ratio, especially in symptomatic focal versus idiopathic generalized epileptic ones. |
2023-02-22 |
2023-03-06 |
Not clear |
| Heng-Chang Zhang, Yang Du, Lei Chen, Zeng-Qiang Yuan, Yong Chen. MicroRNA Schizophrenia: Etiology, Biomarkers and Therapeutic Targets. Neuroscience and biobehavioral reviews vol issue 2023 36707012 |
it is now commonly believed that in addition to the traditional dopaminergic mesolimbic pathway, the etiology of schizophrenia also includes neuronal networks, such as glutamate, gaba, serotonin, bdnf, oxidative stress, inflammation and the immune system. |
2023-01-27 |
2023-01-31 |
human |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Corrigendum to' Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice' [Journal of Ginseng Research Volume 46, Issue 6, November 2022, Pages 819-829]. Journal of ginseng research vol 47 issue 1 2023 36644391 |
corrigendum to' anxiolytic effect of korean red ginseng through upregulation of serotonin and gaba transmission and bdnf expression in immobilized mice' [journal of ginseng research volume 46, issue 6, november 2022, pages 819-829]. |
2023-01-16 |
2023-01-30 |
mouse |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research vol 46 issue 6 2022 36312738 |
anxiolytic effect of korean red ginseng through upregulation of serotonin and gaba transmission and bdnf expression in immobilized mice. |
2022-10-31 |
2023-01-30 |
mouse |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research vol 46 issue 6 2022 36312738 |
the present study investigated the effect of krg on immobilization-induced anxiety-like behaviors in mice and explored the involvement of the serotonin and gaba systems and bdnf in the anxiolytic action. |
2022-10-31 |
2023-01-30 |
mouse |
| Yaiza M Arenas, Mar Mart\\xc3\\xadnez-Garc\\xc3\\xada, Marta Llansola, Vicente Felip. Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia. International journal of molecular sciences vol 23 issue 19 2022 36233065 |
enhanced bdnf and trkb activation enhance gaba neurotransmission in cerebellum in hyperammonemia. |
2022-10-14 |
2023-01-30 |
rat |
| Yaiza M Arenas, Mar Mart\\xc3\\xadnez-Garc\\xc3\\xada, Marta Llansola, Vicente Felip. Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia. International journal of molecular sciences vol 23 issue 19 2022 36233065 |
in the cerebellum of hyperammonemic rats, increased bdnf levels enhance trkb activation in purkinje neurons, leading to increased gad65, gad67 and gaba levels. |
2022-10-14 |
2023-01-30 |
rat |
| Yongchao Gao, Chao Sun, Ting Gao, Zhiyong Liu, Zhao Yang, Hui Deng, Peng Fan, Junhong Ga. Taurine ameliorates volatile organic compounds-induced cognitive impairment in young rats Frontiers in veterinary science vol 9 issue 2022 36187803 |
moreover, taurine decreased malondialdehyde (mda), \xce\xb3-aminobutyric acid (gaba), aspartate aminotransferase (ast), alanine aminotransferase (alt), urea, creatinine (crea) and injury biomarker level, enhanced superoxide dismutase (sod), reduced glutathione (gsh) and glutamic acid (glu) activities, up-regulated the protein expression of brain derived neurotrophic factor (bdnf) and n-methyl-d-aspartate receptor 1 (nmdar1) in model rats, and in most of cases 1% but not 0.5%, ameliorated the defects induced by vocs. |
2022-10-03 |
2023-01-30 |
rat |
| Nikita S Persaud, Hannah M Cate. The Epigenetics of Anxiety Pathophysiology: A DNA Methylation and Histone Modification Focused Review. eNeuro vol issue 2022 35998298 |
in this review, we summarize and discuss a plethora of dna methylation, histone modification, and associated gene expression differences underscoring the anxiety phenotype.findings we outline include expression changes of various dmnts and changes in histone modifications that affect the hypothalamic pituitary adrenal axis and stress response as well as gaba, glutamate, and bdnf signaling in the pfc, amygdala, hypothalamus, and hippocampus. |
2022-08-23 |
2023-01-30 |
Not clear |
| Tessa J Helman, John P Headrick, Jason N Peart, Nicolas J C Stapelber. Central and cardiac stress resiliences consistently linked to integrated immuno-neuroendocrine responses across stress models in male mice. The European journal of neuroscience vol issue 2022 35763309 |
highly integrated expression of hpa axis, neuro-inflammatory, bdnf, monoamine, gaba, cannabinoid and opioid signalling genes was confirmed across conditions, and consistent/potentially causal correlations identified for: i) locomotor activity (noradrenaline, ghrelin; fc crhr1, tnfrsf1b, il33, nfkb1, maoa, gabra1; hippocampal il33); ii) thigmotaxis (adrenaline, leptin); iii) anxiety-like behaviour (adrenaline, leptin; fc tnfrsf1a; hippocampal il33); iv) depressive-like behaviour (ghrelin; fc/hippocampal s100a8); and v) cardiac stress-resistance (noradrenaline, leptin; fc il33, tnfrsf1b, htr1a, gabra1, gabrg2; hippocampal il33, tnfrsf1a, maoa, drd2). |
2022-06-28 |
2023-01-27 |
mouse |
| Emilio Merlo Pich, Laura Cavalleri, Caterina Toma, Ginetta Coll. Involvement of DA D3 Receptors in Structural Neuroplasticity of Selected Limbic Brain Circuits: Possible Role in Treatment-Resistant Depression. Current topics in behavioral neurosciences vol issue 2022 35538302 |
converging studies point to evidence of structural plasticity in circuits operated by glutamate, gaba, dopamine, and serotonin neurotransmitters, in concert with neurotrophic factors such as brain derived neurotrophic factor (bdnf) or insulin growth factor 1 (igf1) and a series of modulators that include circulating hormones. |
2022-05-10 |
2023-01-27 |
human |
| Maria Bove, Stefania Schiavone, Paolo Tucci, Vladyslav Sikora, Stefania Dimonte, Anna Laura Colia, Maria Grazia Morgese, Luigia Trabac. Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms. Progress in neuro-psychopharmacology & biological psychiatry vol issue 2022 35460811 |
in addition, we found decreased bdnf and enhanced gfap hippocampal expression levels, accompanied by elevations in glutamate amount, as well as reduction in gaba content in amygdala and hippocampus. |
2022-04-23 |
2023-01-27 |
mouse |
| Alex Brocchi, Eleni Rebelos, Angela Dardano, Michele Mantuano, Giuseppe Daniel. Effects of Intermittent Fasting on Brain Metabolism. Nutrients vol 14 issue 6 2022 35334932 |
key molecular players modified during if and involved in its beneficial central effects (ketone bodies, bdnf, gaba, gh/igf-1, fgf2, sirtuin-3, mtor, and gut microbiota) are identified and discussed. |
2022-03-26 |
2023-01-27 |
Not clear |
| Yosra A Hussien, Dina F Mansour, Somaia A Nada, Sahar S Abd El-Rahman, Rania M Abdelsalam, Amina S Attia, Dalia M El-Tanboul. Linagliptin attenuates thioacetamide-induced hepatic encephalopathy in rats: Modulation of C/EBP-\\xce\\xb2 and CX3CL1/Fractalkine, neuro-inflammation, oxidative stress and behavioral defects. Life sciences vol issue 2022 35134437 |
lng modulated taa-induced disturbances in hippocampal amino acids; glutamate, and gaba with a significant increase in hippocampal bdnf. |
2022-02-08 |
2023-01-27 |
rat |
| Andra Ionescu-Tucker, Christopher W Butler, Nicole C Berchtold, Dina P Matheos, Marcelo A Wood, Carl W Cotma. Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner. Frontiers in aging neuroscience vol 13 issue 2021 34970138 |
gaba receptor expression, which modulates bdnf secretion, is also modulated by exercise and h3k9me3. |
2021-12-31 |
2023-01-26 |
mouse |
| Andra Ionescu-Tucker, Christopher W Butler, Nicole C Berchtold, Dina P Matheos, Marcelo A Wood, Carl W Cotma. Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner. Frontiers in aging neuroscience vol 13 issue 2021 34970138 |
overall, h3k9me3 repression at bdnf and gaba receptor promoters decreased with age. |
2021-12-31 |
2023-01-26 |
mouse |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.) vol 150 issue Pt B 2021 34863499 |
in addition, semen sojae praeparatum significantly promoted the contents of norepinephrine (ne), 5-hydroxytryptamine (5-ht), brain-derived neurotrophic factor (bdnf), and gamma-aminobutyric acid (gaba) in the hippocampus and the content of bdnf in the serum (p\xc2\xa0<\xc2\xa00.05). |
2021-12-05 |
2023-01-26 |
rat |
| Yanlan Chen, Nan Xiao, Yuxin Chen, Xinye Chen, Chunfei Zhong, Yuying Cheng, Bing Du, Pan L. Semen Sojae Praeparatum alters depression-like behaviors in chronic unpredictable mild stress rats via intestinal microbiota. Food research international (Ottawa, Ont.) vol 150 issue Pt B 2021 34863499 |
genus ruminococcaceae_ucg-008 was positively correlated with gaba and bdnf levels in the hippocampus; genus lactobacillus had a positive correlation with 5-ht; and genus bacteroides had negative correlations with 5-ht, bdnf, and ne. |
2021-12-05 |
2023-01-26 |
rat |