| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sabrina Theresia Müller, Andreas Buchmann, Melanie Haynes, Carmen Ghisleni, Christopher Ritter, Ruth Tuura, Gregor Hasle. Negative association between left prefrontal GABA concentration and BDNF serum concentration in young adults. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32490241. |
the brain's major inhibitory neurotransmitter gamma-aminobutyric acid (gaba) and the brain-derived neurotrophic factor (bdnf) play important roles in several stress-related disorders. |
2020-09-28 |
2023-08-13 |
human |
| Sabrina Theresia Müller, Andreas Buchmann, Melanie Haynes, Carmen Ghisleni, Christopher Ritter, Ruth Tuura, Gregor Hasle. Negative association between left prefrontal GABA concentration and BDNF serum concentration in young adults. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32490241. |
we investigated the relationship between gaba concentration in the left dorsolateral prefrontal cortex (dlpfc) and bdnf concentration in the serum in a community-based sample of young subjects. |
2020-09-28 |
2023-08-13 |
human |
| Zhi-Long Zhang, Yu-Gang Gao, Pu Zang, Pei-Pei Gu, Yan Zhao, Zhong-Mei He, Hong-Yan Zh. [Research progress on mechanism of gastrodin and p-hydroxybenzyl alcohol on central nervous system]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 2. 2020-06-23. PMID:32237313. |
they alleviate hippocampal neuronal toxicity mainly by regulating a variety of neurotransmitters, such as acetylcholine, glutamic acid(glu), γ-aminobutyric acid(gaba), serotonin(5-ht), dopamine(da), norepinephrine(ne), 5-indoleacetic acid(5-hiaa), high vanillic acid(hva) and dihydroxyphenylacetic acid(dopac), pro-inflammatory cell growth factors, such as il-1β, il-6 and tnf-α and relevant receptor functions, and exert neuropharmacological effects by effectively increasing mrna expressions of brain neurotrophic factors, such as bdnf and gdnf, and further inhibiting the apoptosis of damaged neurons. |
2020-06-23 |
2023-08-13 |
Not clear |
| Susanne Weigend, Sebastian C Holst, Valérie Treyer, Ruth L O'Gorman Tuura, Josefine Meier, Simon M Ametamey, Alfred Buck, Hans-Peter Landol. Dynamic changes in cerebral and peripheral markers of glutamatergic signaling across the human sleep-wake cycle. Sleep. vol 42. issue 11. 2020-05-13. PMID:31304973. |
other brain metabolites (gaba, n-acetyl-aspartate, choline, glutathione) and serum bdnf levels were not altered by sleep deprivation (pall > 0.6). |
2020-05-13 |
2023-08-13 |
mouse |
| Rajamani Selvam, Mason L Yeh, Eric S Levin. Endogenous cannabinoids mediate the effect of BDNF at CA1 inhibitory synapses in the hippocampus. Synapse (New York, N.Y.). 2020-04-17. PMID:30334291. |
we have previously shown that at inhibitory synapses in layer 2/3 of the somatosensory cortex, bdnf induces the mobilization of endogenous cannabinoids (ecbs) that act retrogradely to suppress gaba release. |
2020-04-17 |
2023-08-13 |
Not clear |
| Hyunjung Oh, Sean C Piantadosi, Brad R Rocco, David A Lewis, Simon C Watkins, Etienne Sibill. The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression. Biological psychiatry. vol 85. issue 6. 2020-02-03. PMID:30449530. |
a parallel downregulation of brain-derived neurotrophic factor (bdnf) and somatostatin (sst), a marker of inhibitory gamma-aminobutyric acid interneurons that target pyramidal cell dendrites, has been reported in several brain areas of subjects with major depressive disorder (mdd). |
2020-02-03 |
2023-08-13 |
human |
| Susanne Meis, Thomas Endres, Thomas Munsch, Volkmar Lessman. Impact of Chronic BDNF Depletion on GABAergic Synaptic Transmission in the Lateral Amygdala. International journal of molecular sciences. vol 20. issue 17. 2020-01-27. PMID:31484392. |
we therefore analyzed the impact of chronic bdnf depletion on gaba |
2020-01-27 |
2023-08-13 |
Not clear |
| Md Haider Ali, Prabhat R Napit, A S M Hasan Mahmood, Khaggeswar Bheemanapally, Hussain N Alhamami, Md Main Uddin, Santosh K Mandal, Mostafa M H Ibrahim, K P Brisk. Hindbrain estrogen receptor regulation of ventromedial hypothalamic glycogen metabolism and glucoregulatory transmitter expression in the hypoglycemic male rat. Neuroscience. vol 409. 2020-01-09. PMID:30954669. |
hypoglycemic up-regulation of nitric oxide (no) and brain-derived neurotrophic factor (bdnf) signaling was correspondingly driven by erα or -β, whereas gaba and steroidogenic factor-1 were respectively suppressed independently of er input or by erβ. |
2020-01-09 |
2023-08-13 |
rat |
| James W Grau, Yung-Jen Huan. Metaplasticity within the spinal cord: Evidence brain-derived neurotrophic factor (BDNF), tumor necrosis factor (TNF), and alterations in GABA function (ionic plasticity) modulate pain and the capacity to learn. Neurobiology of learning and memory. vol 154. 2019-09-23. PMID:29635030. |
metaplasticity within the spinal cord: evidence brain-derived neurotrophic factor (bdnf), tumor necrosis factor (tnf), and alterations in gaba function (ionic plasticity) modulate pain and the capacity to learn. |
2019-09-23 |
2023-08-13 |
Not clear |
| Manar A Nader, Hayam Ateyya, Mohamed El-Shafey, Nagla A El-Sherbeen. Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy pathways. Neurochemistry international. vol 115. 2019-09-17. PMID:29032011. |
neuronal damage was also assessed by performing tissue staining by hematoxylin and eosin, estimating hippocampus level of glutamate, gamma-aminobutyric acid (gaba), glial fibrillary acidic protein (gfap) and brain-derived neurotrophic factor (bdnf). |
2019-09-17 |
2023-08-13 |
mouse |
| Marion Soto, Clémence Herzog, Julian A Pacheco, Shiho Fujisaka, Kevin Bullock, Clary B Clish, C Ronald Kah. Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism. Molecular psychiatry. vol 23. issue 12. 2019-09-17. PMID:29910467. |
these effects are associated with changes in the levels of tryptophan, gaba, bdnf, amino acids, and multiple acylcarnitines, and are transferable to germ-free mice by fecal transplant. |
2019-09-17 |
2023-08-13 |
mouse |
| Jie Feng, Qing Zhang, Chengliang Zhang, Zhongmin Wen, Xianju Zho. The Effect of sequential bilateral low-frequency rTMS over dorsolateral prefrontal cortex on serum level of BDNF and GABA in patients with primary insomnia. Brain and behavior. vol 9. issue 2. 2019-08-12. PMID:30609300. |
the effect of sequential bilateral low-frequency rtms over dorsolateral prefrontal cortex on serum level of bdnf and gaba in patients with primary insomnia. |
2019-08-12 |
2023-08-13 |
Not clear |
| Sawsan Aboul-Fotouh, Mohamed Habib, Tarek Asaad, Samar K Kassim, Mohamed H Ghane. Behavioral effects of toll-like receptor-4 antagonist 'eritoran' in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and γ-aminobutyric acid/glutamate balance. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29561292. |
long-term administration of eri ameliorated crs-induced depressive-like symptoms and hypothalamic-pituitary-adrenal axis hyperactivity alongside reducing levels of hippocampal and pfc inflammatory cytokines, restoring gaba and glutamate balance, and enhancing pfc and hippocampal neurogenesis, by increasing bdnf gene and protein expression in a dose-dependent manner. |
2019-07-31 |
2023-08-13 |
rat |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
compared to young mice, bdnf messenger rna (mrna) and protein levels and those core neuroplasticity factors (neurotransmitter γ-aminobutyric acid [gaba] level, gabaa-r α2 and α5 subunits expression and gaba+ neurons) in hippocampus markedly decreased with anxiety-like behavior in aged mice. |
2019-07-22 |
2023-08-13 |
mouse |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
gene knockdown mice model indicates the mechanism of low bdnf function in llad, particularly affecting gaba neurons, therefore bridging the neurotrophic factor and gabaergic neuroplasticity hypotheses of llad. |
2019-07-22 |
2023-08-13 |
mouse |
| Jennifer Rakotomamonjy, Abdel Mouman Ghoumar. Brain-Derived Neurotrophic Factor Is Required for the Neuroprotective Effect of Mifepristone on Immature Purkinje Cells in Cerebellar Slice Culture. International journal of molecular sciences. vol 20. issue 2. 2019-04-26. PMID:30642045. |
however, interestingly, bdnf haploinsufficiency impairs neuronal survival induced by mifepristone and gaba |
2019-04-26 |
2023-08-13 |
mouse |
| Shuai Lian, Bin Xu, Di Wang, Lipeng Wang, Wenjie Li, Ruizhi Yao, Hong Ji, Jianfa Wang, Jingru Guo, Shize Li, Huanmin Yan. Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats. Behavioural brain research. vol 359. 2019-04-19. PMID:30423388. |
to further understand the effects of prenatal cold stress on offspring, we investigated the behavior change; the expression of glucocorticoid receptor (gr), mineralocorticoid receptor (mr), brain-derived neurotrophic factor (bdnf), insulin-like growth factor 1 receptor (igf1r), neuronal nuclei (neun), glial fibrillary acidic protein (gfap), corticotropin-releasing hormone receptor 1 (crhr1), gamma-aminobutyric acid b receptor, 2 (gabab2) proteins in hippocampus; the ratio of cd4/cd8 lymphocyte subsets and the level of norepinephrine (ne), dopamine (da) in the peripheral blood of weaned offspring rats using behavioral tests and biology analysis methods. |
2019-04-19 |
2023-08-13 |
rat |
| Hiroshi Maejima, Shuta Ninuma, Akane Okuda, Takahiro Inoue, Masataka Hayash. Exercise and low-level GABA Neuroscience letters. vol 685. 2019-03-07. PMID:30037768. |
exercise and low-level gaba aerobic exercise is known to increase expression of brain-derived neurotrophic factor (bdnf) in the hippocampus and to improve cognitive function. |
2019-03-07 |
2023-08-13 |
Not clear |
| Bojan Zalar, Alexander Haslberger, Borut Peterli. The Role of Microbiota in Depression - a brief review. Psychiatria Danubina. vol 30. issue 2. 2018-09-06. PMID:29930222. |
there are changes in gut microbiota composition and gut microbial profile (butyrate, gaba, β-hydroxybutyrate) effecting epigenetic regulation (histone acetylation, dna methylation) and gene expression of receptors and mediators (slc6a4, bdnf, gaba, gprs) involved in depressive disorders. |
2018-09-06 |
2023-08-13 |
Not clear |
| Megan L Brady, Jyotsna Pilli, Joshua M Lorenz-Guertin, Sabyasachi Das, Charles E Moon, Nicholas Graff, Tija C Jaco. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. vol 128. 2018-07-17. PMID:29074304. |
depolarizing, inhibitory gaba type a receptor activity regulates gabaergic synapse plasticity via erk and bdnf signaling. |
2018-07-17 |
2023-08-13 |
Not clear |