| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
swimming and l-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker lc3, gaba and bdnf-trkb pathway in the spinal cord of rats. |
2023-03-04 |
2023-03-06 |
rat |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
the study aim was to assess the effect of swimming training (sw) and l-arginine loaded chitosan nanoparticles (la-cnps) on the sensory and motor neuron population, autophagy marker lc3, total oxidant status/total antioxidant capacity, behavioural test, gaba and bdnf-trkb pathway in the spinal cord of aging rats. |
2023-03-04 |
2023-03-06 |
rat |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
the old sw\xe2\x80\x89+\xe2\x80\x89la-cnps group increased (improved) spinal cord gaba (p\xe2\x80\x89=\xe2\x80\x890.0187), bdnf (p\xe2\x80\x89=\xe2\x80\x890.0003), trkb (p\xe2\x80\x89<\xe2\x80\x890.0001) gene expression, decreased autophagy marker lc3 protein (p\xe2\x80\x89<\xe2\x80\x890.0001), nerve atrophy and jumping/licking latency (p\xe2\x80\x89<\xe2\x80\x890.0001), improved sciatic functional index score and total oxidant status/total antioxidant capacity compared to the old group (p\xe2\x80\x89<\xe2\x80\x890.0001). |
2023-03-04 |
2023-03-06 |
rat |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
in conclusion, swimming and la-cnps seems to ameliorate aging-induced neuron atrophy, autophagy marker lc3, oxidant-antioxidant status, functional restoration, gaba and bdnf-trkb pathway in the spinal cord of aging rats. |
2023-03-04 |
2023-03-06 |
rat |
| Kimberly Howard-Quijano, Yuki Kuwabara, Tomoki Yamaguchi, Kenny Roman, Siamak Salavatian, Bradley Taylor, Aman Mahaja. GABAergic Signaling During Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model. Anesthesiology vol issue 2023 36724342 |
we hypothesize that spinal cord stimulation reduces myocardial ischemia/reperfusion induced sympathetic excitation and ventricular arrhythmias through \xce\xb3-aminobutyric acid (gaba) mediated pathways in the thoracic spinal cord. |
2023-02-01 |
2023-03-06 |
Not clear |
| Xiaolong Zheng, Bo Zhu, Jiang Xu, Dong Liu, Yan Huang, Daiqi Chen, Zhixian Liu, Fangliang Guo, Yuanji Dong, Wenzhen Zhu, Dengji Pan, Su-Chun Zhang, Hong Chen, Wei Wan. Human spinal GABA neurons survive and mature in the injured nonhuman primate spinal cord. Stem cell reports vol issue 2023 36669493 |
human spinal gaba neurons survive and mature in the injured nonhuman primate spinal cord. |
2023-01-20 |
2023-01-30 |
rat |
| Xiaolong Zheng, Bo Zhu, Jiang Xu, Dong Liu, Yan Huang, Daiqi Chen, Zhixian Liu, Fangliang Guo, Yuanji Dong, Wenzhen Zhu, Dengji Pan, Su-Chun Zhang, Hong Chen, Wei Wan. Human spinal GABA neurons survive and mature in the injured nonhuman primate spinal cord. Stem cell reports vol issue 2023 36669493 |
grafted human spinal gaba neurons survived for up to 7.5\xc2\xa0months in the injured monkey spinal cord and retained their intrinsic properties, becoming mature and growing axons and forming synapses. |
2023-01-20 |
2023-01-30 |
rat |
| Lauryn E New, Yuchio Yanagawa, Glenn A McConkey, Jim Deuchars, Susan A Deuchar. GABAergic regulation of cell proliferation within the adult mouse spinal cord. Neuropharmacology vol issue 2022 36336067 |
thus, intrinsic spinal cord gaba levels are correlated with the extent of cell proliferation, providing important evidence for manipulating these levels. |
2022-11-06 |
2023-01-30 |
mouse |
| Lauryn E New, Yuchio Yanagawa, Glenn A McConkey, Jim Deuchars, Susan A Deuchar. GABAergic regulation of cell proliferation within the adult mouse spinal cord. Neuropharmacology vol issue 2022 36336067 |
diazepam binding inhibitor, an endogenous protein that interacts with gaba receptors and its breakdown product, octadecaneuropeptide, which preferentially activates central benzodiazepine (cbr) sites, were highly expressed in spinal cord, especially in ependymal cells surrounding the central canal. |
2022-11-06 |
2023-01-30 |
mouse |
| Lauryn E New, Yuchio Yanagawa, Glenn A McConkey, Jim Deuchars, Susan A Deuchar. GABAergic regulation of cell proliferation within the adult mouse spinal cord. Neuropharmacology vol issue 2022 36336067 |
altering endogenous gaba levels or modulating gabaergic signaling through specific sites on gaba receptors therefore influences nsc proliferation in the adult spinal cord. |
2022-11-06 |
2023-01-30 |
mouse |
| Xue Ya. The Role of GABA in Spinal Cord Injury. Neurospine vol 19 issue 3 2022 36203292 |
the role of gaba in spinal cord injury. |
2022-10-07 |
2023-01-30 |
Not clear |
| Krishnapriya Hari, Ana M Lucas-Osma, Krista Metz, Shihao Lin, Noah Pardell, David A Roszko, Sophie Black, Anna Minarik, Rahul Singla, Marilee J Stephens, Robert A Pearce, Karim Fouad, Kelvin E Jones, Monica A Gorassini, Keith K Fenrich, Yaqing Li, David J Bennet. GABA facilitates spike propagation through branch points of sensory axons in the spinal cord. Nature neuroscience vol issue 2022 36163283 |
gaba facilitates spike propagation through branch points of sensory axons in the spinal cord. |
2022-09-26 |
2023-01-30 |
Not clear |
| Kelsey E Hudson, James W Gra. Ionic Plasticity: Common Mechanistic Underpinnings of Pathology in Spinal Cord Injury and the Brain. Cells vol 11 issue 18 2022 36139484 |
spinal cord injury (sci) can bring about a modification that weakens the inhibitory effect of gaba in the central gray caudal to injury. |
2022-09-23 |
2023-01-30 |
Not clear |
| Stanislava Jergova, Melissa Hernandez, Jacqueline Sage. Analgesic effect of recombinant GABAergic precursors releasing MVIIA in a model of peripheral nerve injury in rats. Molecular pain vol issue 2022 36113096 |
development of chronic pain has been attributed to dysfunctional gaba signaling in the spinal cord. |
2022-09-16 |
2023-01-30 |
rat |
| Thu\\xe1\\xbb\\xb3 Linh Ph\\xe1\\xba\\xa1m, Chan Noh, Chiranjivi Neupane, Ramesh Sharma, Hyun Jin Shin, Ki Duk Park, C Justin Lee, Hyun-Woo Kim, So Yeong Lee, Jin Bong Par. MAO-B inhibitor, KDS2010, alleviates spinal nerve ligation-induced neuropathic pain in rats through competitively blocking the BDNF/TrkB/NR2B signaling. The journal of pain vol issue 2022 35940543 |
our previous study has demonstrated that kds2010 (kds), a newly developed reversible mao-b inhibitor, could attenuate paclitaxel (ptx)-induced tactile hypersensitivity in mice through suppressing reactive oxidant species (ros)-decreased inhibitory gaba synaptic transmission in the spinal cord. |
2022-08-08 |
2023-01-30 |
rat |
| Suyong Kim, Juan Gang, Ji-Hwan Lee, Hyejin Yang, Chunhoo Cheon, Seong-Gyu Ko, Hyunsu Bae, Woojin Ki. [6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice. Pharmaceuticals (Basel, Switzerland) vol 15 issue 6 2022 35745645 |
[6]-shogaol attenuates oxaliplatin-induced allodynia through serotonergic receptors and gaba in the spinal cord in mice. |
2022-06-24 |
2023-01-27 |
mouse |
| Diveyaa Sivakumar, Rosmaliza Raml. GABAergic signalling in modulation of dental pain. European journal of pharmacology vol issue 2022 35429491 |
gaba and its receptors have been found in parts of the spinal cord and brain that are related to pain perception, thus providing compelling evidence of its role in mediating pain signalling. |
2022-04-16 |
2023-01-27 |
Not clear |
| Mingwei Zhao, Caifeng Shao, Jiaxue Dong, Qian Chen, Rui Ma, Ping Jiang, Wei-Ning Zhang, Kun Yan. GABA Brain structure & function vol issue 2022 35318502 |
gaba the substantia gelatinosa (sg, lamina ii of spinal cord gray matter) is pivotal for modulating nociceptive information from the peripheral to the central nervous system. |
2022-03-23 |
2023-01-27 |
Not clear |
| Xiangzhe Li, Xinjian Song, Lu Fang, Jie Ding, Longju Qi, Qinghua Wang, Chuanming Dong, Sheng Wang, Jiahuan Wu, Tong Wang, Qinfeng W. Body Weight-Supported Treadmill Training Ameliorates Motoneuronal Hyperexcitability by Increasing GAD-65/67 and KCC2 Expression via TrkB Signaling in Rats with Incomplete Spinal Cord Injury. Neurochemical research vol issue 2022 35320460 |
the critical reasons are reducing the synthesis of gamma-aminobutyric acid (gaba), glycine and potassium chloride co-transporter 2 (kcc2) inside the distal spinal cord. |
2022-03-23 |
2023-01-27 |
rat |
| Xiangzhe Li, Xinjian Song, Lu Fang, Jie Ding, Longju Qi, Qinghua Wang, Chuanming Dong, Sheng Wang, Jiahuan Wu, Tong Wang, Qinfeng W. Body Weight-Supported Treadmill Training Ameliorates Motoneuronal Hyperexcitability by Increasing GAD-65/67 and KCC2 Expression via TrkB Signaling in Rats with Incomplete Spinal Cord Injury. Neurochemical research vol issue 2022 35320460 |
the current work aimed to test whether exercise training could increase the expression of glutamic acid decarboxylase 65/67 (gad-65/67, the key enzymes in gaba synthesis) and kcc2 in the distal spinal cord via tropomyosin-related kinase b (trkb) signaling. |
2022-03-23 |
2023-01-27 |
rat |