| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asiye Nurten, M Zafer Gören, Nurdan Tekin, Mert Kaşkal, Nurhan Engina. Assessing effects of tamoxifen on tolerance, dependence, and glutamate and glutamine levels in frontal cortex and hippocampus in chronic morphine treatment. Behavioural brain research. 2024-02-08. PMID:38331101. |
confirming previous findings, tamoxifen (2mg/kg) decreased glutamate and glutamine concentrations in the hippocampus in animals with placebo pellets. |
2024-02-08 |
2024-02-11 |
mouse |
| Ekaterina P Aleksandrova, Andrey P Ivlev, Alexey A Kulikov, Alexandra A Naumova, Margarita V Glazova, Elena V Chernigovskay. Audiogenic kindling activates glutamatergic system in the hippocampus of rats with genetic predisposition to audiogenic seizures. Brain research. 2024-02-07. PMID:38325559. |
thus, after 14 ags, simultaneous increase in metabotropic glutamate receptor mglur1 and decrease in ionotropic n-methyl-d-aspartate (nmda) receptors could reflect compensatory anti-epileptic mechanism, while further kindling progression induced upregulation of ionotropic receptors, probably, contributing to the hippocampal epileptization. |
2024-02-07 |
2024-02-10 |
rat |
| Ekaterina P Aleksandrova, Andrey P Ivlev, Alexey A Kulikov, Alexandra A Naumova, Margarita V Glazova, Elena V Chernigovskay. Audiogenic kindling activates glutamatergic system in the hippocampus of rats with genetic predisposition to audiogenic seizures. Brain research. 2024-02-07. PMID:38325559. |
altogether, obtained results suggested that overactivation of glutamate production in the hippocampus strongly contributed to tle development in km rats. |
2024-02-07 |
2024-02-10 |
rat |
| Bin Mei, Xiaoxia Xu, Juntao Weng, Yueyue Yang, Peng Wang, Gaolin Qiu, Chi Zhang, Qunlin Zhang, Yao Lu, Xuesheng Li. Activating astrocytic α2A adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice. Brain, behavior, and immunity. 2024-02-06. PMID:38320682. |
activating astrocytic α2a adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice. |
2024-02-06 |
2024-02-09 |
mouse |
| Bin Mei, Xiaoxia Xu, Juntao Weng, Yueyue Yang, Peng Wang, Gaolin Qiu, Chi Zhang, Qunlin Zhang, Yao Lu, Xuesheng Li. Activating astrocytic α2A adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice. Brain, behavior, and immunity. 2024-02-06. PMID:38320682. |
this study was performed to determine whether hippocampal astrocytic α2a-ar activation confers neuroprotection against sae and whether this protective effect is astrocyte specific and achieved by the modulation of glutamate metabolism. |
2024-02-06 |
2024-02-09 |
mouse |
| Liam T Ralph, John Georgiou, Graham L Collingridge, Patrick Tidbal. Sex-dependence of synaptic depression induced by activation of metabotropic glutamate receptors in rat hippocampus. Brain and neuroscience advances. vol 8. 2024-02-01. PMID:38298523. |
sex-dependence of synaptic depression induced by activation of metabotropic glutamate receptors in rat hippocampus. |
2024-02-01 |
2024-02-03 |
rat |
| Chao Zhang, Kaihua Zhang, Xin Hu, Xianyun Cai, Yufan Chen, Fei Gao, Guangbin Wan. Regional GABA levels modulate abnormal resting-state network functional connectivity and cognitive impairment in multiple sclerosis. Cerebral cortex (New York, N.Y. : 1991). 2024-01-25. PMID:38271282. |
for this purpose, we used a combination of magnetic resonance spectroscopy and resting-state functional magnetic resonance imaging to study gamma-aminobutyric acid and glutamate concentrations in the posterior cingulate cortex, medial prefrontal cortex and left hippocampus, and inter-network functional connectivity in 29 relapsing-remitting multiple sclerosis patients and 34 matched healthy controls. |
2024-01-25 |
2024-01-28 |
Not clear |
| A C Akinmoladun, Ibrahim Saliu, Olaoluwa Abilogun, Omotola Helen Ajibola, Zainab Abiola Amoo, Olubukola Benedicta Ojo, Ebenezer O Farombi, Mary Tolulope Olaley. Comparative influence of kolaviron and coenzyme Q10 on complex I activity, glutamate clearance, 3,4-dihydroxyphenethylamine metabolism, and redox stress in rotenone-induced neurotoxicity. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 37. issue 2. 2024-01-20. PMID:38243568. |
this study examined the comparative influence of kolaviron and coenzyme q10 on complex i activity, dopamine metabolism, glutamate clearance, and redox stress in rotenone-induced neurotoxicity in the cortex, hippocampus, and striatum of the brain of rats. |
2024-01-20 |
2024-01-22 |
rat |
| A C Akinmoladun, Ibrahim Saliu, Olaoluwa Abilogun, Omotola Helen Ajibola, Zainab Abiola Amoo, Olubukola Benedicta Ojo, Ebenezer O Farombi, Mary Tolulope Olaley. Comparative influence of kolaviron and coenzyme Q10 on complex I activity, glutamate clearance, 3,4-dihydroxyphenethylamine metabolism, and redox stress in rotenone-induced neurotoxicity. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 37. issue 2. 2024-01-20. PMID:38243568. |
on the cortical, hippocampal, and striatal regions of the brain, complex i activity, dopamine metabolism, oxidative stress markers, as well as glutamate metabolism were carried out and analyzed. |
2024-01-20 |
2024-01-22 |
rat |
| Ruqayyah Ibiyeye, Fatimo Sulaimon, Aminu Imam, Misturah Adana, Akeem Okesina, Moyosore Aja. Phoenix dactylifera and polyphenols ameliorated monosodium glutamate toxicity in the dentate gyrus of Wistar rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 38. issue 1. 2024-01-19. PMID:38243365. |
monosodium glutamate (msg) has been known to cause neurodegeneration, due to its ability to trigger excitotoxicity, and the hippocampus is one of the most affected regions. |
2024-01-19 |
2024-01-22 |
rat |
| Carolina Aguado, Sara Badesso, José Martínez-Hernández, Alejandro Martín-Belmonte, Rocío Alfaro-Ruiz, Miriam Fernández, Ana Esther Moreno-Martínez, Mar Cuadrado-Tejedor, Ana García-Osta, Rafael Lujá. Resilience to structural and molecular changes in excitatory synapses in the hippocampus contributes to cognitive function recovery in Tg2576 mice. Neural regeneration research. vol 19. issue 9. 2024-01-16. PMID:38227537. |
intriguingly, through quantitative immunoelectron microscopy in the hippocampus of impaired and resilient tg2576 transgenic ad mice, we uncovered differences in the subcellular localization of glutamate receptors. |
2024-01-16 |
2024-01-18 |
mouse |
| Jiahui Chen, Yinlong Li, QingZhen Yu, Jimmy S Patel, Xin Zhou, Kuo Zhang, Jian Rong, Chunyu Zhao, Ahmad F Chaudhary, Wei Zhang, Chunyang Bi, Zhendong Song, April T Davenport, Ahmed Haider, James B Daunais, Lee Collier, Hongjie Yuan, Steven Lian. Preclinical Evaluation of Azabenzimidazole-Based PET Radioligands for γ-8 Dependent Transmembrane AMPA Receptor Regulatory Protein Imaging. Chembiochem : a European journal of chemical biology. 2024-01-16. PMID:38227784. |
ampa glutamate receptors (ampars) play a pivotal role in excitatory neurotransmission, particularly in the hippocampus where the tarp γ-8 subunit is enriched and serves as a target for emerging anti-epileptic drugs. |
2024-01-16 |
2024-01-19 |
rat |
| Huizhen Sun, Shanshan Wei, Yanchun Gong, Kaizhi Ding, Shan Tang, Wei Sun, Chunhua Yuan, Liping Huang, Zhibing Liu, Chong Chen, Lihua Ya. Neuroprotective effects of cordycepin inhibit glutamate-induced apoptosis in hippocampal neurons. Cell stress & chaperones. 2024-01-14. PMID:38219840. |
the results showed that glutamate toxicity reduced hippocampal neuron viability, increased ros production, and increased intracellular calcium levels. |
2024-01-14 |
2024-01-17 |
Not clear |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
both drugs influenced glutamate and gaba release in the nucleus accumbens, hippocampus and amygdala and increased ach levels in the hippocampus. |
2024-01-11 |
2024-01-13 |
rat |
| Xing Ye, Jun-Yi Lin, Ling-Xia Chen, Xue-Chun Wu, Kai-Jun Ma, Bei-Xu Li, You-Xin Fan. SREBP1 deficiency diminishes glutamate-mediated HT22 cell damage and hippocampal neuronal pyroptosis induced by status epilepticus. Heliyon. vol 10. issue 1. 2024-01-11. PMID:38205297. |
additionally, we treated ht22 hippocampal cells with glutamate to create neuronal injury models in vitro. |
2024-01-11 |
2024-01-13 |
rat |
| Xiaonan Wang, Fuping Zhang, Le Niu, Junni Yan, Huanhuan Liu, Di Wang, Juan Hui, Haiyue Dai, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity. Journal of affective disorders. 2023-12-30. PMID:38159655. |
and rtms intervention reversed the elevated glutamate concentration in the hippocampus of cums rats using an elisa kit. |
2023-12-30 |
2024-01-05 |
rat |
| Wenxue Liu, Min Jia, Keyin Zhang, Jiang Chen, Xiyu Zhu, Ruisha Li, Zhenjun Xu, Yanyu Zang, Yapeng Wang, Jun Pan, Daqing Ma, Jianjun Yang, Dongjin Wan. Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. Aging cell. 2023-12-29. PMID:38155547. |
the high neuroinflammatory state induced by surgery resulted in glutamate accumulation in the extrasynaptic space, which subsequently decreased the excitability of pyramidal neurons and increased the pv interneurons inhibition through enhancing n-methyl-d-aspartate receptors' tonic currents in the hippocampus. |
2023-12-29 |
2023-12-31 |
mouse |
| Xiang Wu, Jian Liu, Yanping Hui, Zhongheng Wu, Ling Wang, Yixuan Wang, Yihua Bai, Jing Li, Lei Zhang, Yue Xi, Qiaojun Zhang, Libo L. Long-term intermittent theta burst stimulation enhanced hippocampus-dependent memory by regulating hippocampal theta oscillation and neurotransmitter levels in healthy rats. Neurochemistry international. 2023-12-29. PMID:38157888. |
however, it remains largely unknown whether this effect is achieved by regulating hippocampal theta oscillation and neurotransmitters gamma-aminobutyric acid (gaba) and glutamate, which are strongly related to memory. |
2023-12-29 |
2024-01-05 |
rat |
| Xiang Wu, Jian Liu, Yanping Hui, Zhongheng Wu, Ling Wang, Yixuan Wang, Yihua Bai, Jing Li, Lei Zhang, Yue Xi, Qiaojun Zhang, Libo L. Long-term intermittent theta burst stimulation enhanced hippocampus-dependent memory by regulating hippocampal theta oscillation and neurotransmitter levels in healthy rats. Neurochemistry international. 2023-12-29. PMID:38157888. |
thus, we investigated the effect of 14 days of itbs on hippocampus-dependent memory and further explored the roles of hippocampal theta oscillation and neurotransmitters gaba and glutamate in this effect. |
2023-12-29 |
2024-01-05 |
rat |
| Katia Cortese, Maria Cristina Gagliani, Luca Raiter. Interactions between Glycine and Glutamate through Activation of Their Transporters in Hippocampal Nerve Terminals. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137373. |
interactions between glycine and glutamate through activation of their transporters in hippocampal nerve terminals. |
2023-12-23 |
2023-12-25 |
mouse |