| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katia Cortese, Maria Cristina Gagliani, Luca Raiter. Interactions between Glycine and Glutamate through Activation of Their Transporters in Hippocampal Nerve Terminals. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137373. |
our main aims here were: (i) to investigate release-regulating, transporter-mediated interactions between glycine and glutamate in hippocampal nerve terminals and (ii) to determine the coexistence of transporters for glycine and glutamate in these terminals. |
2023-12-23 |
2023-12-25 |
mouse |
| b' Andrijana Stanisavljevi\\xc4\\x87 Ili\\xc4\\x87, Sne\\xc5\\xbeana \\xc4\\x90or\\xc4\\x91evi\\xc4\\x87, Drago\\xc5\\xa1 Inta, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139008.' |
we determined the effect of olz on pv-positive (+) and glutamate decarboxylase 67 (gad67) + cell numbers in the layers of dorsal hippocampus (dhipp) cornu ammonis (ca1-ca3) and dentate gyrus (dg) subregions in rats exposed to chronic social isolation (csis), which is an animal model of depression. |
2023-12-23 |
2023-12-25 |
rat |
| María Sancho-Alonso, Yaiza M Arenas, Paula Izquierdo-Altarejos, Mar Martinez-Garcia, Marta Llansola, Vicente Felip. Enhanced Activation of the S1PR2-IL-1β-Src-BDNF-TrkB Pathway Mediates Neuroinflammation in the Hippocampus and Cognitive Impairment in Hyperammonemic Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139078. |
the signaling pathways inducing neuroinflammation and altered glutamate receptors were analyzed in hippocampal slices. |
2023-12-23 |
2023-12-25 |
rat |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk. Cell reports. vol 43. issue 1. 2023-12-20. PMID:38117654. |
we find that the receptor tyrosine kinase (rtk) trkb and the g-protein-coupled receptor (gpcr) metabotropic glutamate receptor 5 (mglur5) together mediate hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-12-20 |
2023-12-23 |
Not clear |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
[effect of suanzaoren decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
enzyme-linked immunosorbent assay(elisa) was used to measure the levels of glutamate(glu) and γ-aminobutyric acid(gaba) in the rat hippocampus. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
real-time fluorescence quantitative pcr(qrt-pcr) and western blot were employed to assess the gene and protein expression of ionotropic glutamate receptors in the hippocampal region. |
2023-12-19 |
2023-12-23 |
mouse |
| Ping Li, Yang Liu, Man-Shu Zou, Ting-Ting Wang, Hai-Peng Guo, Ting-Ting Ren, Ying He, Hua Wang, Yu-Hong Wan. [Neuroprotective effect and mechanism of Zuogui Jiangtang Jieyu Formula on diabetes mellitus complicated with depression model rats based on CX3CL1-CX3CR1 axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114178. |
western blot was used to measure the expression levels of cx3cl1, cx3cr1, a2a adenosine receptor(a2ar), glutamate receptor 2a(nr2a), glutamate receptor 2b(nr2b), and brain-derived neurotrophic factor(bdnf) in the hippocampus. |
2023-12-19 |
2023-12-23 |
rat |
| Sung M Yang, Ayan Ghoshal, Jeffrey M Hubbard, Florian Gackière, Romain Teyssié, Stuart A Neale, Seth C Hopkins, Kenneth S Koblan, Linda J Bristow, Nina Dedi. TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-19. PMID:38110609. |
taar1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. |
2023-12-19 |
2023-12-21 |
mouse |
| Sung M Yang, Ayan Ghoshal, Jeffrey M Hubbard, Florian Gackière, Romain Teyssié, Stuart A Neale, Seth C Hopkins, Kenneth S Koblan, Linda J Bristow, Nina Dedi. TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-19. PMID:38110609. |
here we assessed the impact of ulotaront (sep-363856), a taar1 agonist in phase iii clinical development for schizophrenia, on glutamate function in the mouse striatum and hippocampus. |
2023-12-19 |
2023-12-21 |
mouse |
| Megha Kumari, Yasha Hasija, Richa Trived. Acute and sub-acute metabolic change in different brain regions induced by moderate blunt traumatic brain injury. Neuroreport. 2023-12-08. PMID:38064354. |
changes in myo-inositol, creatine, glutamate, succinate, lactate, and n-acetyl aspartic acid in hippocampal tissues were observed at day 3 pi. |
2023-12-08 |
2023-12-17 |
rat |
| Zhen Zeng, Jing He, Tao Ya. Characteristic early changes of Glu and Cho in brain regions affected by different types of subjective cognitive decline and their clinical significance. Medicine. vol 102. issue 49. 2023-12-08. PMID:38065860. |
using the bilateral hippocampus, left posterior cingulate gyrus (pcg), and frontal lobe as regions of interest, the scope under the peak of n-acetylaspartate (naa), choline complex (cho), glutamate (glu), metabolic images (mi), and creatine (cr) was tested. |
2023-12-08 |
2023-12-17 |
human |
| Mudan Cai, Hee Ra Park, Eun Jin Yan. Electroacupuncture modulates glutamate neurotransmission to alleviate PTSD-like behaviors in a PTSD animal model. Translational psychiatry. vol 13. issue 1. 2023-11-24. PMID:37993441. |
additionally, ea treatment decreased glutamate levels and glutamate neurotransmission-related proteins (pnr1 and nr2b) in the hippocampus of a ptsd model. |
2023-11-24 |
2023-11-28 |
mouse |
| Ming-Shang Pai, Kaw-Chen Wang, Kun-Chieh Yeh, Su-Jane Wan. Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats. European journal of pharmacology. 2023-11-24. PMID:38000721. |
chlorogenic acid pretreatment also resulted in a significant reduction in glutamate elevation and neuronal death in the hippocampus of kainic acid-treated rats. |
2023-11-24 |
2023-11-28 |
rat |
| Ming-Shang Pai, Kaw-Chen Wang, Kun-Chieh Yeh, Su-Jane Wan. Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats. European journal of pharmacology. 2023-11-24. PMID:38000721. |
additionally, the levels of mitochondrial function-related proteins, including sirtuin 3, complex i, glutamate dehydrogenase 1 and atp synthase, were increased, and the level of the mitochondrial damage marker cytochrome c was decreased in the hippocampus of chlorogenic acid/kainic acid rats. |
2023-11-24 |
2023-11-28 |
rat |
| Yizhou Zhang, Meiqin Chen, Huan Chen, Shixiong Mi, Chang Wang, Hongchun Zuo, Leigang Song, Juan Du, Huixian Cui, Sha L. Testosterone reduces hippocampal synaptic damage in an androgen receptor-independent manner. The Journal of endocrinology. 2023-11-22. PMID:37991884. |
our results showed that testosterone ameliorated spatial memory deficit and neuronal damage, and increased dendritic spines density and postsynaptic density protein 95 (psd95) and glutamate receptor 1 (glua1) expression in the hippocampus of tfm male mice. |
2023-11-22 |
2023-11-29 |
mouse |
| Alicja Skórkowska, Weronika Krzyżanowska, Beata Bystrowska, Roberta Torregrossa, Matthew Whiteman, Bartosz Pomierny, Bogusława Budziszewsk. The hydrogen sulfide donor AP39 reduces glutamate-mediated excitotoxicity in a rat model of brain ischemia. Neuroscience. 2023-11-22. PMID:37993086. |
the results showed a significant longitudinal decrease in extracellular glutamate concentrations in the motor cortex and hippocampus in mcao+ap39 rats compared to mcao rats. |
2023-11-22 |
2023-11-29 |
rat |
| Adriana Fernanda K Vizuete, Fernanda Fróes, Marina Seady, Fernanda Hansen, Rodrigo Ligabue-Braun, Carlos-Alberto Gonçalves, Diogo O Souz. A Mechanism of Action of Metformin in the Brain: Prevention of Methylglyoxal-Induced Glutamatergic Impairment in Acute Hippocampal Slices. Molecular neurobiology. 2023-11-18. PMID:37980327. |
we suggest a new role of metformin in the glutamate system, whereby it protects the hippocampus against the derangements of the glutamatergic system induced by mg, possibly by phosphorylation via pkc ζ (4). |
2023-11-18 |
2023-11-20 |
Not clear |
| Mauricio Quezada, Carolina Ponce, Pablo Berríos-Cárcamo, Daniela Santapau, Javiera Gallardo, Cristian De Gregorio, María Elena Quintanilla, Paola Morales, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Paula Andrés-Herrera, Lucia Hipólito, Fernando Ezque. Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence. CNS neuroscience & therapeutics. 2023-11-06. PMID:37927136. |
the morphine-induced increases in neuroinflammation, brain oxidative stress, and alteration of glutamate levels in the hippocampus and nucleus accumbens have been associated with morphine dependence and a higher severity of withdrawal symptoms. |
2023-11-06 |
2023-11-08 |
human |
| Bataa M A El-Kafoury, Enas A Abdel-Hady, Wesam El Bakly, Wael M Elayat, Ghada Galal Hamam, Samar M M Abd El Rahman, Noha N Lashee. Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway. Scientific reports. vol 13. issue 1. 2023-10-30. PMID:37898621. |
correspondingly, there was an elevation of hippocampal ach, glutamate, and mda levels; accompanied by up-regulation of hippocampal sirt1 and atg7 gene expression. |
2023-10-30 |
2023-11-08 |
rat |