| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos Morgan, Patricio Sáez-Briones, Rafael Barra, Andrea Reyes, Katherine Zepeda-Morales, Luis Constandil, Miguel Ríos, Paulina Ramírez, Héctor Burgos, Alejandro Hernánde. Prefrontal Cortical Control of Activity in Nucleus Accumbens Core Is Weakened by High-Fat Diet and Prevented by Co-Treatment with N-Acetylcysteine: Implications for the Development of Obesity. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077493. |
a loss of neuroplastic control on nucleus accumbens (nac) neuronal activity exerted by the medial prefrontal cortex (mpfc) through long-term depression (ltd) is involved in triggering drug-seeking behavior and relapse on several substances of abuse due to impaired glutamate homeostasis in tripartite synapses of the nucleus accumbens (nac) core. |
2022-09-09 |
2023-08-14 |
mouse |
| Yvonne S Yang, Richard J Maddock, Huailin Zhang, Junghee Lee, Gerhard Hellemann, Stephen R Marder, Michael F Gree. N-Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study. Psychiatry research. Neuroimaging. vol 325. 2022-07-15. PMID:35839558. |
we found that nac treatment was associated with increased glutathione (statistically significant) and decreased glutamate (trend-level) compared with placebo in medial prefrontal cortex but not dorsolateral prefrontal cortex. |
2022-07-15 |
2023-08-14 |
Not clear |
| Jozef Mizera, Grzegorz Kazek, Bartosz Pomierny, Beata Bystrowska, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamiol. Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring. Molecular neurobiology. 2022-06-30. PMID:35773600. |
sex-dependent changes in glutamate levels were identified in extracellular fluid obtained from the medial prefrontal cortex and the hippocampus of the offspring. |
2022-06-30 |
2023-08-14 |
human |
| Scott A Kinlein, Naomi K Wallace, Marina I Savenkova, Ilia N Karatsoreo. Chronic hypothalamic-pituitary-adrenal axis disruption alters glutamate homeostasis and neural responses to stress in male C57Bl6/N mice. Neurobiology of stress. vol 19. 2022-06-20. PMID:35720261. |
using laser microdissection and transcriptomic analyses, we show that chronic disruption of the hpa axis alters the expression of genes related to glutamate signaling in the medial prefrontal cortex (mpfc), hippocampus, and amygdala. |
2022-06-20 |
2023-08-14 |
mouse |
| Lakshmi Rajagopal, Mei Huang, Wenqi He, Chelsea Ryan, Ahmad Elzokaky, Pradeep Banerjee, Herbert Y Meltze. Repeated administration of rapastinel produces exceptionally prolonged rescue of memory deficits in phencyclidine-treated mice. Behavioural brain research. 2022-06-19. PMID:35718230. |
both rapastinel (3mg/kg) and ketamine (30mg/kg), moderately increased the efflux of dopamine, norepinephrine, and serotonin in medial prefrontal cortex; however, only ketamine increased cortical glutamate efflux. |
2022-06-19 |
2023-08-14 |
mouse |
| Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiol. Disruption of Glutamate Homeostasis in the Brain of Rat Offspring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet. Nutrients. vol 14. issue 11. 2022-06-10. PMID:35683984. |
glutamate concentration was assessed in extracellular fluid samples collected from the medial prefrontal cortex and hippocampus of male and female offspring. |
2022-06-10 |
2023-08-14 |
rat |
| Elizabeth Woo, Dibyadeep Datta, Amy F T Arnste. Glutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex. Frontiers in neuroanatomy. vol 16. 2022-04-21. PMID:35444520. |
glutamate metabotropic receptor type 3 (mglu3) localization in the rat prelimbic medial prefrontal cortex. |
2022-04-21 |
2023-08-13 |
rat |
| Brooke Naylor, Negin Hesam-Shariati, James H McAuley, Simon Boag, Toby Newton-John, Caroline D Rae, Sylvia M Gusti. Corrigendum: Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain. Frontiers in neurology. vol 13. 2022-04-04. PMID:35370916. |
corrigendum: reduced glutamate in the medial prefrontal cortex is associated with emotional and cognitive dysregulation in people with chronic pain. |
2022-04-04 |
2023-08-13 |
Not clear |
| Xin-Miao Wu, Mu-Huo Ji, Xiao-Yu Yin, Han-Wen Gu, Ting-Ting Zhu, Run-Zhu Wang, Jian-Jun Yang, Jin-Chun She. Reduced inhibition underlies early life LPS exposure induced-cognitive impairment: Prevention by environmental enrichment. International immunopharmacology. vol 108. 2022-04-04. PMID:35378446. |
the protein levels of glutamic acid decarboxylas67 (gad67), parvalbumin (pv), vesicular gaba amino acid transporter (vgat) and vesicular glutamate transporters (vglut1) were determined in the hippocampi and medial prefrontal cortex (mpfc). |
2022-04-04 |
2023-08-13 |
mouse |
| Zachary A Rodd, Eric A Engleman, William A Truitt, Andrew R Burke, Andrei I Molosh, Richard L Bell, Sheketha R Hause. CNO administration increases dopamine and glutamate in the medial prefrontal cortex of wistar rats: Further concerns for the validity of the CNO-activated DREADD procedure. Neuroscience. 2022-03-30. PMID:35351573. |
cno administration increases dopamine and glutamate in the medial prefrontal cortex of wistar rats: further concerns for the validity of the cno-activated dreadd procedure. |
2022-03-30 |
2023-08-13 |
rat |
| Zachary A Rodd, Eric A Engleman, William A Truitt, Andrew R Burke, Andrei I Molosh, Richard L Bell, Sheketha R Hause. CNO administration increases dopamine and glutamate in the medial prefrontal cortex of wistar rats: Further concerns for the validity of the CNO-activated DREADD procedure. Neuroscience. 2022-03-30. PMID:35351573. |
the current study examined the effects of peripheral administration of cno on glutamate and da levels in the medial prefrontal cortex (mpfc). |
2022-03-30 |
2023-08-13 |
rat |
| Adeyelu Tolulope, Olalekan M Ogundel. Anterior thalamic glutamatergic neurons modulate prefrontal cortical firing and regularity. Neuroscience letters. 2022-03-12. PMID:35278647. |
the diencephalic nucleus is rich in excitatory glutamate neurons that project to both the hippocampus and medial prefrontal cortex (mpfc). |
2022-03-12 |
2023-08-13 |
Not clear |
| Arjun Ghuman, Alyssa McEwen, Kim Hoang Tran, Nicholas Mitchell, Chris Hanstock, Peter Seres, Gian Jhangri, Denee Burgess, Glen Baker, Jean-Michel Le Melled. Prospective investigation of glutamate levels and percentage gray matter in the medial prefrontal cortex in females at risk for postpartum depression. Current neuropharmacology. 2022-03-03. PMID:35236264. |
prospective investigation of glutamate levels and percentage gray matter in the medial prefrontal cortex in females at risk for postpartum depression. |
2022-03-03 |
2023-08-13 |
Not clear |
| Arjun Ghuman, Alyssa McEwen, Kim Hoang Tran, Nicholas Mitchell, Chris Hanstock, Peter Seres, Gian Jhangri, Denee Burgess, Glen Baker, Jean-Michel Le Melled. Prospective investigation of glutamate levels and percentage gray matter in the medial prefrontal cortex in females at risk for postpartum depression. Current neuropharmacology. 2022-03-03. PMID:35236264. |
we have shown that glutamate (glu) levels in the medial prefrontal cortex (mpfc) decrease during perimenopause, a period of increased risk of developing a major depressive episode. |
2022-03-03 |
2023-08-13 |
Not clear |
| Davin R Peart, Allyson K Andrade, Carly N Logan, Lori A Knackstedt, Jennifer E Murra. Regulation of Cocaine-related Behaviors by Estrogen and Progesterone. Neuroscience and biobehavioral reviews. 2022-02-21. PMID:35189163. |
these opposing effects of 17ß-estradiol and progesterone/allopregnanolone involve endocannabinoid, γ-aminobutyric acid, dopamine, and glutamate transmission in the medial prefrontal cortex and striatum. |
2022-02-21 |
2023-08-13 |
rat |
| Sidney Yap, Jessica Luki, Christopher C Hanstock, Peter Seres, Tami Shandro, Sarah E C Hanstock, Alynna Lirette, Huaying Helen Zhao, Katherine J Aitchison, Jean-Michel Le Melled. Decreased Medial Prefrontal Cortex Glutamate Levels in Perimenopausal Women. Frontiers in psychiatry. vol 12. 2021-12-30. PMID:34966302. |
decreased medial prefrontal cortex glutamate levels in perimenopausal women. |
2021-12-30 |
2023-08-13 |
Not clear |
| Bogdan Feliks Kania, Danuta Wrońska, Izabela Szpręgiel, Urszula Brach. Glutamate as a Stressoric Factor for the Ex Vivo Release of Catecholamines from the Rabbit Medial Prefrontal Cortex (mPFC). Life (Basel, Switzerland). vol 11. issue 12. 2021-12-24. PMID:34947917. |
glutamate as a stressoric factor for the ex vivo release of catecholamines from the rabbit medial prefrontal cortex (mpfc). |
2021-12-24 |
2023-08-13 |
rabbit |
| A M McEwen, D T A Burgess, S E C Hanstock, C C Hanstock, P Seres, P Khalili, S C Newman, G B Baker, N D Mitchell, P S Allen, J-M Le Melled. Glutamate levels in the medial prefrontal cortex of healthy pregnant women compared to non-pregnant controls. Psychoneuroendocrinology. vol 133. 2021-12-10. PMID:34419762. |
glutamate levels in the medial prefrontal cortex of healthy pregnant women compared to non-pregnant controls. |
2021-12-10 |
2023-08-13 |
Not clear |
| YuanYuan Hou, YunLei Wang, ShaoFei Song, Yao Zuo, HaoJie Zhang, Chen Bai, HaiTao Zhao, Tong Zhan. Long-term variable photoperiod exposure impairs the mPFC and induces anxiety and depression-like behavior in male wistar rats. Experimental neurology. vol 347. 2021-12-03. PMID:34710402. |
we compared the numbers of neurons, astrocytes, and dendritic spines; dendrite morphology; long-term potentiation (ltp), long-term depression (ltd) and paired-pulse ratio (ppr); expression of glutamate receptor [n-methyl-d-aspartate receptor (nmdar) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar)] subunits and brain-derived neurotrophic factor (bdnf) in the medial prefrontal cortex (mpfc); and the anxiety and depression behaviors between rats in the circadian misalignment (cm) and circadian alignment (ca, with normal circadian rhythm) groups. |
2021-12-03 |
2023-08-13 |
rat |
| Santosh Pothula, Taro Kato, Rong-Jian Liu, Min Wu, Danielle Gerhard, Ryota Shinohara, Alexa-Nicole Sliby, Golam M I Chowdhury, Kevin L Behar, Gerard Sanacora, Pradeep Banerjee, Ronald S Duma. Cell-type specific modulation of NMDA receptors triggers antidepressant actions. Molecular psychiatry. vol 26. issue 9. 2021-11-15. PMID:32488125. |
we demonstrate that rapastinel directly enhances nmdar activity on principal glutamatergic neurons in medial prefrontal cortex (mpfc) without any effect on glutamate efflux, while ketamine blocks nmdar on gaba interneurons to cause glutamate efflux and indirect activation of excitatory synapses. |
2021-11-15 |
2023-08-13 |
human |