| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| In-Sun Choi, Jin-Hwa Cho, Maan-Gee Lee, Il-Sung Jan. Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons. Neuropharmacology. vol 93. 2016-01-01. PMID:25656480. |
enzymatic conversion of atp to adenosine contributes to atp-induced inhibition of glutamate release in rat medullary dorsal horn neurons. |
2016-01-01 |
2023-08-13 |
rat |
| In-Sun Choi, Jin-Hwa Cho, Maan-Gee Lee, Il-Sung Jan. Enzymatic conversion of ATP to adenosine contributes to ATP-induced inhibition of glutamate release in rat medullary dorsal horn neurons. Neuropharmacology. vol 93. 2016-01-01. PMID:25656480. |
here we report another type of atp-induced presynaptic modulation of glutamate release in rat medullary dorsal horn neurons. |
2016-01-01 |
2023-08-13 |
rat |
| Shinji Matsumura, Wataru Taniguchi, Kazuhiko Nishida, Terumasa Nakatsuka, Seiji It. In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model. The European journal of neuroscience. vol 41. issue 7. 2015-12-29. PMID:25645012. |
furthermore, acute inflammation-associated structural changes in the spinal dorsal horn were shown to be mediated by glutamate receptor activation. |
2015-12-29 |
2023-08-13 |
mouse |
| Jaime L Watson, Tamara J Hala, Rajarshi Putatunda, Daniel Sannie, Angelo C Lepor. Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury. PloS one. vol 9. issue 9. 2015-12-21. PMID:25268642. |
following injury, an increase in the number of neurons expressing Δfosb (a marker of chronic neuronal activation), persistent astrocyte activation and proliferation (as measured by gfap and ki67 expression), and a decrease in the expression of the astrocyte glutamate transporter glt1 are observed in the ipsilateral superficial dorsal horn of cervical spinal cord. |
2015-12-21 |
2023-08-13 |
mouse |
| David Bravo, Paula Ibarra, Jeffri Retamal, Teresa Pelissier, Claudio Laurido, Alejandro Hernandez, Luis Constandi. Pannexin 1: a novel participant in neuropathic pain signaling in the rat spinal cord. Pain. vol 155. issue 10. 2015-11-24. PMID:25102401. |
panx1 channels are highly permeable to calcium and adenosine triphosphatase (atp); on the other hand, they can be opened by atp and glutamate, two crucial molecules for acute and chronic pain signaling in the spinal cord dorsal horn, thus suggesting that panx1 could be a key component for the generation of central sensitization during persistent pain. |
2015-11-24 |
2023-08-13 |
human |
| Jing Yang, Wei Wang, Zheng Yong, Weidong Mi, Hong Zhan. Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats. Iranian journal of basic medical sciences. vol 18. issue 8. 2015-11-11. PMID:26557972. |
propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats. |
2015-11-11 |
2023-08-13 |
rat |
| Jing Yang, Wei Wang, Zheng Yong, Weidong Mi, Hong Zhan. Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats. Iranian journal of basic medical sciences. vol 18. issue 8. 2015-11-11. PMID:26557972. |
the objective of this study was to investigate the effects of increasing dosage of propofol on the release of glutamate (glu), γ-aminobutyric acid (gaba) and glycine (gly) in the spinal dorsal horn. |
2015-11-11 |
2023-08-13 |
rat |
| Dylan W Maixner, Xisheng Yan, Mei Gao, Ruchi Yadav, Han-Rong Wen. Adenosine Monophosphate-activated Protein Kinase Regulates Interleukin-1β Expression and Glial Glutamate Transporter Function in Rodents with Neuropathic Pain. Anesthesiology. vol 122. issue 6. 2015-07-24. PMID:25710409. |
neuroinflammation and dysfunctional glial glutamate transporters (gts) in the spinal dorsal horn are implicated in the genesis of neuropathic pain. |
2015-07-24 |
2023-08-13 |
Not clear |
| Rajarshi Putatunda, Tamara J Hala, Jeannie Chin, Angelo C Lepor. Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, GLT1, in superficial dorsal horn. Brain research. vol 1581. 2015-05-21. PMID:24833066. |
chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, glt1, in superficial dorsal horn. |
2015-05-21 |
2023-08-13 |
rat |
| Rajarshi Putatunda, Tamara J Hala, Jeannie Chin, Angelo C Lepor. Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, GLT1, in superficial dorsal horn. Brain research. vol 1581. 2015-05-21. PMID:24833066. |
furthermore, dysregulation of extracellular glutamate homeostasis and chronic astrocyte activation play important underlying roles in persistent hyperexcitability of these superficial dorsal horn neurons. |
2015-05-21 |
2023-08-13 |
rat |
| Rajarshi Putatunda, Tamara J Hala, Jeannie Chin, Angelo C Lepor. Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter, GLT1, in superficial dorsal horn. Brain research. vol 1581. 2015-05-21. PMID:24833066. |
finally, persistent astrocyte activation and significantly reduced expression of the major cns glutamate transporter, glt1, in superficial dorsal horn astrocytes are associated with both excitability changes in stt neurons and the neuropathic pain behavioral phenotype. |
2015-05-21 |
2023-08-13 |
rat |
| Yasushi Kuraish. [A memoir of my research on pain and analgesia for 39 years]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 134. issue 11. 2015-05-15. PMID:25366910. |
we have found that noxious mechanical and thermal stimuli to the skin increase the release of substance p and somatostatin, respectively, from the dorsal horn in situ, and that noradrenaline inhibits the release of substance p and glutamate from primary afferents. |
2015-05-15 |
2023-08-13 |
Not clear |
| Christoph Ficker, Katalin Rozmer, Erzsébet Kató, Rómeó D Andó, Luisa Schumann, Ute Krügel, Heike Franke, Beáta Sperlágh, Thomas Riedel, Peter Ille. Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species. Glia. vol 62. issue 10. 2015-05-11. PMID:24895290. |
astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via p2x7 receptor-mediated release of glutamate and reactive oxygen species. |
2015-05-11 |
2023-08-13 |
Not clear |
| Han-Jun Wang, Rebecca Cahoon, Edgar B Cahoon, Hong Zheng, Kaushik P Patel, Irving H Zucke. Glutamatergic receptor dysfunction in spinal cord contributes to the exaggerated exercise pressor reflex in heart failure. American journal of physiology. Heart and circulatory physiology. vol 308. issue 5. 2015-05-01. PMID:25502111. |
excitatory amino acids (e.g., glutamate) released by contraction-activated skeletal muscle afferents into the dorsal horn of the spinal cord initiate the central component of the exercise pressor reflex (epr) in physiological conditions. |
2015-05-01 |
2023-08-13 |
rat |
| Han-Jun Wang, Rebecca Cahoon, Edgar B Cahoon, Hong Zheng, Kaushik P Patel, Irving H Zucke. Glutamatergic receptor dysfunction in spinal cord contributes to the exaggerated exercise pressor reflex in heart failure. American journal of physiology. Heart and circulatory physiology. vol 308. issue 5. 2015-05-01. PMID:25502111. |
microinjection of glutamate (10 mm, 100 nl) into the l4 or l5 dorsal horn caused a greater pressor response in chf rats compared with sham rats. |
2015-05-01 |
2023-08-13 |
rat |
| Han-Jun Wang, Rebecca Cahoon, Edgar B Cahoon, Hong Zheng, Kaushik P Patel, Irving H Zucke. Glutamatergic receptor dysfunction in spinal cord contributes to the exaggerated exercise pressor reflex in heart failure. American journal of physiology. Heart and circulatory physiology. vol 308. issue 5. 2015-05-01. PMID:25502111. |
molecular evidence showed that the protein expression of glutamate receptors (both non-nmda and nmda) was elevated in the dorsal horn of the lumbar spinal cord in chf rats. |
2015-05-01 |
2023-08-13 |
rat |
| Han-Jun Wang, Rebecca Cahoon, Edgar B Cahoon, Hong Zheng, Kaushik P Patel, Irving H Zucke. Glutamatergic receptor dysfunction in spinal cord contributes to the exaggerated exercise pressor reflex in heart failure. American journal of physiology. Heart and circulatory physiology. vol 308. issue 5. 2015-05-01. PMID:25502111. |
in addition, data from microdialysis experiments demonstrated that although basal glutamate release at the dorsal horn at rest was similar between sham and chf rats (225 ± 50 vs. 260 ± 63 nm in sham vs. chf rats, n = 4, p > 0.05), chf rats exhibit greater glutamate release into the dorsal horn during muscle contraction compared with sham rats (549 ± 60 vs. 980 ± 65 nm in sham vs. chf rats, n = 4, p < 0.01). |
2015-05-01 |
2023-08-13 |
rat |
| M Gao, X Yan, H-R Wen. Inhibition of glycogen synthase kinase 3β activity with lithium prevents and attenuates paclitaxel-induced neuropathic pain. Neuroscience. vol 254. 2015-02-23. PMID:24070631. |
in this study, we uncovered that increased activation of glycogen synthase kinase 3beta (gsk3β) in the spinal dorsal horn was concurrently associated with increased protein expressions of gfap, il-1β and a decreased protein expression of glial glutamate transporter 1 (glt-1), as well as the development and maintenance of taxol-induced neuropathic pain. |
2015-02-23 |
2023-08-12 |
Not clear |
| Lianxi Zhang, Kumiko Tanabe, Fumi Yanagidate, Yasuhiko Kawasaki, Guihua Chen, Shuji Dohi, Hiroki Iid. Different effects of local anesthetics on extracellular signal-regulated kinase phosphorylation in rat dorsal horn neurons. European journal of pharmacology. vol 734. 2015-01-28. PMID:24726558. |
glutamate, which is released from presynaptic fibers, activates extracellular signal-regulated kinase (erk) through nmda and ampa receptors in spinal dorsal horn neurons. |
2015-01-28 |
2023-08-13 |
rat |
| Tally M Largent-Milnes, Deborah M Hegarty, Sue A Aicher, Michael C Andrese. Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons. Journal of neurophysiology. vol 111. issue 11. 2015-01-24. PMID:24598529. |
physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons. |
2015-01-24 |
2023-08-12 |
rat |