| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Su-Ting Jiang, Shu-Ying Lian, Yao-Huan Sun, Mei-Bo Pan, Bin Wang, Hui Wang, Jun Hua, Yi-Chen Wang, Qiu-Ling Wang, Yin-Feng Don. The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice. Experimental gerontology. 2024-04-13. PMID:38614224. |
to elucidate the potential role of oxytocin, we subjected pair-housed psd mice to treatment with an oxytocin receptor (oxtr) antagonist (l368,889) (5 mg/kg, i.p, once a day) for 3 weeks. |
2024-04-13 |
2024-04-16 |
mouse |
| Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. |
prefrontal cortex and hypothalamic oxytocin receptor (oxtr) expression levels were identified using western blot analysis. |
2024-03-31 |
2024-04-03 |
rat |
| Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. |
while oxtr expression levels in the prefrontal cortex did not vary according to the body weight and oxytocin application, oxtr levels in the hypothalamus were higher in the hfd- and/or oxytocin-treated animals. |
2024-03-31 |
2024-04-03 |
rat |
| Xiaoxiao Zheng, Feng Zhou, Meina Fu, Lei Xu, Jiayuan Wang, Jialin Li, Keshuang Li, Cornelia Sindermann, Christian Montag, Benjamin Becker, Yang Zhan, Keith M Kendric. Patterns of neural activity in response to threatening faces are predictive of autistic traits: modulatory effects of oxytocin receptor genotype. Translational psychiatry. vol 14. issue 1. 2024-03-30. PMID:38553454. |
autistic individuals generally demonstrate impaired emotion recognition but it is unclear whether effects are emotion-specific or influenced by oxytocin receptor (oxtr) genotype. |
2024-03-30 |
2024-04-01 |
human |
| Sara M Freeman, J Leon Catrow, James Eric Cox, Alexandra Turano, McKenna A Rich, Hillary P Ihrig, Naveena Poudyal, Cheng-Wei Tom Chang, Eric M Gese, Julie K Young, Aaron L Olse. Binding Affinity, Selectivity, and Pharmacokinetics of the Oxytocin Receptor Antagonist L-368,899 in the Coyote ( Comparative medicine. vol 74. issue 1. 2024-03-27. PMID:38532262. |
binding affinity, selectivity, and pharmacokinetics of the oxytocin receptor antagonist l-368,899 in the coyote ( l-368,899 is a selective small-molecule oxytocin receptor (oxtr) antagonist originally developed in the 1990s to prevent preterm labor. |
2024-03-27 |
2024-03-29 |
monkey |
| Martin Köhne, Emilia Diel, Eva-Maria Packeiser, Denny Böttcher, Anna Tönissen, Christin Unruh, Sandra Goericke-Pesch, Reiner Ulrich, Harald Siem. Analysis of gene and protein expression in the endometrium for validation of an ex vivo model of the equine uterus using PCR, digital and visual histopathology. Theriogenology. vol 221. 2024-03-27. PMID:38537320. |
mrna expression levels of progesterone (pgr), estrogen (esr1) and oxytocin (oxtr) receptor as well as of mki67 (marker of cell growth) and casp3 (marker of apoptosis) were analyzed by rt-qpcr, and correlation to protein abundance was validated by immunohistochemical staining. |
2024-03-27 |
2024-03-30 |
Not clear |
| Samantha L Awalt, Lidia Boghean, David Klinkebiel, Rosemary Strasse. A dog's life: Early life histories influence methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes, cortisol levels, and attachment styles. Developmental psychobiology. vol 66. issue 3. 2024-03-14. PMID:38482889. |
a dog's life: early life histories influence methylation of glucocorticoid (nr3c1) and oxytocin (oxtr) receptor genes, cortisol levels, and attachment styles. |
2024-03-14 |
2024-03-16 |
human |
| Samantha L Awalt, Lidia Boghean, David Klinkebiel, Rosemary Strasse. A dog's life: Early life histories influence methylation of glucocorticoid (NR3C1) and oxytocin (OXTR) receptor genes, cortisol levels, and attachment styles. Developmental psychobiology. vol 66. issue 3. 2024-03-14. PMID:38482889. |
we examined 47 owner-dog dyads, including dogs rescued from abusive or neglectful environments, and matched control dogs for changes in dna methylation of glucocorticoid (nr3c1) and oxytocin (oxtr) receptor genes previously shown to be affected by early life stress in other species including humans. |
2024-03-14 |
2024-03-16 |
human |
| Tatsuto Kageyama, Jieun Seo, Lei Yan, Junji Fukud. Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38409197. |
here, we examined cinnamic acid, a small molecule activator for oxytocin receptor (oxtr) expression. |
2024-02-28 |
2024-03-01 |
human |
| Yingye Fang, Erin L Reinl, Audrey Liu, Trinidi D Prochaska, Manasi Malik, Antonina I Frolova, Sarah K England, Princess I Imoukhued. Quantification of surface-localized and total oxytocin receptor in myometrial smooth muscle cells. Heliyon. vol 10. issue 4. 2024-02-22. PMID:38384573. |
oxytocin acts through the oxytocin receptor (oxtr) to modulate uterine contractility. |
2024-02-22 |
2024-02-24 |
human |
| Michal Hubert Wrobel, Jaroslaw Mlynarczuk, Robert Rekawieck. Effects of commonly used carbamates (carbaryl and thiram) on the regulatory, secretory and motor functions of bovine cervixes in vitro. Theriogenology. vol 218. 2024-02-08. PMID:38330862. |
carbaryl increased the level of mrna (at a dose of 0.1 ng/ml) and protein (at both doses, 1 and 10 ng/ml) expression for the oxytocin receptor (oxtr), while thiram (at 0.1 and 10 ng/ml or 0.1-10 ng/ml, respectively) caused the opposite effects. |
2024-02-08 |
2024-02-11 |
cattle |
| Rana Ghamari, Mohammad Tahmaseb, Atiye Sarabi-Jamab, Seyed-Alireza Etesami, Azar Mohammadzadeh, Fatemeh Alizadeh, Mehdi Tehrani-Doos. Association of verbal and non-verbal theory of mind abilities with non-coding variants of OXTR in youth with autism spectrum disorder and typically developing individuals: a case-control study. BMC psychiatry. vol 24. issue 1. 2024-01-08. PMID:38191308. |
several studies over the past decade have identified the oxytocin receptor gene (oxtr) and its variants as promising components for explaining the molecular mechanisms underlying theory of mind (tom). |
2024-01-08 |
2024-01-10 |
Not clear |
| Xue Lv, Yue-Sen Hou, Zhao-Hui Zhang, Wei-Hua Yu. OXTR polymorphisms associated with severity and treatment responses of schizophrenia. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-01-06. PMID:38184684. |
taking into account the associations between the oxytocin system and social functions, which are apparently impaired in schizophrenia patients, we hypothesized that the oxytocin receptor gene (oxtr) might be associated with schizophrenia symptoms in both severity and responses to antipsychotics and did this exploratory positional study. |
2024-01-06 |
2024-01-09 |
Not clear |
| Matthijs Moerkerke, Nicky Daniels, Laura Tibermont, Tiffany Tang, Margaux Evenepoel, Stephanie Van der Donck, Edward Debbaut, Jellina Prinsen, Viktoria Chubar, Stephan Claes, Bart Vanaudenaerde, Lynn Willems, Jean Steyaert, Bart Boets, Kaat Alaert. Chronic oxytocin administration stimulates the oxytocinergic system in children with autism. Nature communications. vol 15. issue 1. 2024-01-03. PMID:38167302. |
regarding salivary oxytocin receptor gene (oxtr) epigenetics (dna-methylation), oxytocin-induced reductions in oxtr dna-methylation were observed, suggesting a facilitation of oxytocin receptor expression in the oxytocin compared to the placebo group. |
2024-01-03 |
2024-01-06 |
Not clear |
| Matthijs Moerkerke, Nicky Daniels, Laura Tibermont, Tiffany Tang, Margaux Evenepoel, Stephanie Van der Donck, Edward Debbaut, Jellina Prinsen, Viktoria Chubar, Stephan Claes, Bart Vanaudenaerde, Lynn Willems, Jean Steyaert, Bart Boets, Kaat Alaert. Chronic oxytocin administration stimulates the oxytocinergic system in children with autism. Nature communications. vol 15. issue 1. 2024-01-03. PMID:38167302. |
notably, heightened oxytocin levels post-treatment were significantly associated with reduced oxtr dna-methylation and improved feelings of secure attachment. |
2024-01-03 |
2024-01-06 |
Not clear |
| M Diaz-Marsá, J M López-Villatoro, A De la Torre-Luque, K S MacDowell, A Galvez-Merlin, A Gómez Del Barrio, F Ruiz-Guerrero, L Beato-Fernández, F Polo-Montes, M León-Velasco, D Martín-Hernández, A Carrasco-Diaz, J C Leza, J L Carrasc. Decreased oxytocin plasma levels and oxytocin receptor expression associated with aggressive behavior in aggressive-impulsive disorders. Journal of psychiatric research. vol 170. 2023-12-29. PMID:38157667. |
this study aims to enhance the understanding of the association between the phenotypic and endophenotypic characteristics of impulsive-aggressive disorders, through the study of plasma oxytocin (oxt) and oxytocin receptor (oxtr) levels in patients with borderline personality disorder (bpd) and patients with eating disorders (ed), as well as to examine the relationship of oxt system with aggressive behavior in these disorders. |
2023-12-29 |
2024-01-05 |
Not clear |
| Jelte Wieting, Kirsten Jahn, Stefan Bleich, Helge Frieling, Maximilian Dees. A targeted long-read sequencing approach questions the association of OXTR methylation with high-functioning autism. Clinical epigenetics. vol 15. issue 1. 2023-12-21. PMID:38124130. |
dna sequence variation and altered epigenetic regulation of the oxytocin receptor gene (oxtr) have been implicated in autism and autistic-like behaviors. |
2023-12-21 |
2023-12-23 |
Not clear |
| Huahua Wang, Yuting Deng, Meijin Li, Zhiyuan Tao, Chengfu Y. Parental Psychological Control, the Parent-Adolescent Relationship, and Non-suicidal Self-Injury Among Chinese Adolescents: The Moderating Effect of the Oxytocin Receptor Gene rs53576 Polymorphism. Child psychiatry and human development. 2023-12-19. PMID:38110758. |
considering that genetic and environmental factors interactively influence adolescent development, this study examined whether the parent-adolescent relationship mediated the link between ppc and adolescent nssi, and whether this mediating process was moderated by the oxytocin receptor gene rs53576 polymorphism (oxtr rs53576). |
2023-12-19 |
2023-12-21 |
human |
| Eugenia Annunzi, Loreta Cannito, Fabio Bellia, Francesca Mercante, Matteo Vismara, Beatrice Benatti, Alberto Di Domenico, Riccardo Palumbo, Walter Adriani, Bernardo Dell'Osso, Claudio D'Addari. Mild internet use is associated with epigenetic alterations of key neurotransmission genes in salivary DNA of young university students. Scientific reports. vol 13. issue 1. 2023-12-13. PMID:38092954. |
aim of this study was to investigate epigenetic and genetic regulation of oxytocin receptor (oxtr), dopamine transporter (dat1) and serotonin transporter (sert) genes using dna obtained from saliva samples of young university students: the internet addiction test (iat) was administered to evaluate the potential existence and intensity of ia. |
2023-12-13 |
2023-12-17 |
human |
| Shizu Hidema, Keisuke Sato, Hiroaki Mizukami, Yumi Takahashi, Yuko Maejima, Kenju Shimomura, Katsuhiko Nishimor. Oxytocin receptor-expressing neurons in the medial preoptic area are essential for lactation, whereas those in the lateral septum are not critical for maternal behavior. Neuroendocrinology. 2023-12-10. PMID:38071956. |
in nurturing systems, the oxytocin (oxt)-oxytocin receptor (oxtr) system is important for parturition, and essential for lactation and parental behavior. |
2023-12-10 |
2023-12-17 |
Not clear |