| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Michael Whittaker, Betty Exintari. The Effects of Age on Prostatic Responses to Oxytocin and the Effects of Antagonists. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001957. |
the development of luts may be linked to overexpression of oxytocin receptors (oxtr), resulting in increased baseline myogenic tone within the prostate. |
2023-11-25 |
2023-11-28 |
rat |
| Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Michael Whittaker, Betty Exintari. The Effects of Age on Prostatic Responses to Oxytocin and the Effects of Antagonists. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001957. |
thus, it is hypothesised that targeting oxtr using oxytocin receptor antagonists (atosiban, cligosiban, and β-mercapto-β,β-cyclopentamethylenepropionyl1, o-me-tyr2, orn8]-oxytocin (ßmßßc)), may attenuate myogenic tone within the prostate. |
2023-11-25 |
2023-11-28 |
rat |
| Eman Shawky, Rasha A Nassra, Aliaa M T El-Alkamy, Shaimaa M Sallam, Samah M El Sohaf. Unraveling the mechanisms of Fenugreek seed for managing different gynecological disorders: steroidal saponins and isoflavones revealed as key bioactive metabolites. Journal of pharmaceutical and biomedical analysis. vol 238. 2023-11-24. PMID:38000191. |
the main targets associated with gynecological disorders included estrogen receptor beta (esr2), estrogen-related receptor gamma (gper1), oxytocin receptor (oxtr), progesterone receptor (pgr), prolactin receptor (prlr), and several enzymes involved in sex hormone biosynthesis. |
2023-11-24 |
2023-11-28 |
rat |
| Connor M Aitken, Janine C M Jaramillo, Warren Davis, Liam Brennan-Xie, Stuart J McDougall, Andrew J Lawrence, Philip J Rya. Feeding signals inhibit fluid-satiation signals in the mouse lateral parabrachial nucleus to increase intake of highly palatable, caloric solutions. Journal of neurochemistry. 2023-10-19. PMID:37855271. |
chemogenetic activation of oxytocin receptor-expressing neurons in the parabrachial nucleus (oxtr |
2023-10-19 |
2023-11-08 |
mouse |
| Kaustubh Sharma, Armita A Govar, Bandana Ghimire, Katsuhiko Nishimori, Elizabeth Hammock, Ryoichi Teruyam. Sexually dimorphic oxytocin receptor-expressing (OXTR) neurons in the anteroventral periventricular nucleus (AVPV) in the postpartum female mouse are involved in maternal behavior. Journal of neuroendocrinology. 2023-10-03. PMID:37784240. |
sexually dimorphic oxytocin receptor-expressing (oxtr) neurons in the anteroventral periventricular nucleus (avpv) in the postpartum female mouse are involved in maternal behavior. |
2023-10-03 |
2023-10-07 |
mouse |
| Kaustubh Sharma, Armita A Govar, Bandana Ghimire, Katsuhiko Nishimori, Elizabeth Hammock, Ryoichi Teruyam. Sexually dimorphic oxytocin receptor-expressing (OXTR) neurons in the anteroventral periventricular nucleus (AVPV) in the postpartum female mouse are involved in maternal behavior. Journal of neuroendocrinology. 2023-10-03. PMID:37784240. |
because the avpv is involved in the regulation of maternal behavior and oxytocin enhances its induction, this finding leads to the hypothesis that the female specific population of oxtr neurons in the avpv regulates maternal behavior. |
2023-10-03 |
2023-10-07 |
mouse |
| Manassés Soares Souza, Breno Sanvicente-Vieira, Aline Zaparte, Talita Batista, Maria Aparecida Nagai, Flávia Rotea Mangone, Ana Carolina Pavanelli, Thiago Wendt Viola, Rodrigo Grassi-Oliveir. Cocaine use disorder effects on blood oxytocin levels and OXTR DNA methylation. Neuroscience letters. 2023-10-01. PMID:37778686. |
cocaine use disorder effects on blood oxytocin levels and oxtr dna methylation. |
2023-10-01 |
2023-10-07 |
Not clear |
| Manassés Soares Souza, Breno Sanvicente-Vieira, Aline Zaparte, Talita Batista, Maria Aparecida Nagai, Flávia Rotea Mangone, Ana Carolina Pavanelli, Thiago Wendt Viola, Rodrigo Grassi-Oliveir. Cocaine use disorder effects on blood oxytocin levels and OXTR DNA methylation. Neuroscience letters. 2023-10-01. PMID:37778686. |
in this study, we compared plasma oxytocin and blood dna methylation in the oxtr gene between people with and without cocaine use disorder (cud). |
2023-10-01 |
2023-10-07 |
Not clear |
| Yu-Chieh Hung, Yi-Jen Wu, Miao-Er Chien, Yu-Ting Lin, Cheng-Fang Tsai, Kuei-Sen Hs. Loss of oxytocin receptors in hilar mossy cells impairs social discrimination. Neurobiology of disease. vol 187. 2023-09-30. PMID:37769745. |
hippocampal oxytocin receptor (oxtr) signaling is crucial for discrimination of social stimuli to guide social recognition, but circuit mechanisms and cell types involved remain incompletely understood. |
2023-09-30 |
2023-10-07 |
mouse |
| Ekaterina Delikishkina, Shira Cohen-Zimerman, Zachary R Kachian, Frank Krueger, Barry Gordon, Jordan Grafma. Understanding altruistic behavior: The joint role of prefrontal damage and OXTR genotype. Neuropsychologia. 2023-09-23. PMID:37741549. |
growing evidence suggests that altruism may be partly determined by the oxytocin receptor (oxtr) gene, which regulates the emotions underlying altruistic attitudes, such as empathy and trust. |
2023-09-23 |
2023-10-07 |
human |
| Kah Kheng Goh, Nobuhisa Kanahara, Yi-Hang Chiu, Mong-Liang L. The impact of childhood trauma exposure on social functioning in schizophrenia: the moderated mediation role of oxytocin and oxytocin receptor gene polymorphisms. Psychological medicine. 2023-09-18. PMID:37721215. |
this study investigated the potential role of oxytocin and oxytocin receptor gene (oxtr) in mediating the effects of childhood trauma on social functioning in schizophrenia. |
2023-09-18 |
2023-10-07 |
Not clear |
| Gang Yang, Xiao-Dong Wang, Lu-Ying Chen, Zhen-Yu Wu, Er-Ping Xi, Hui L. Oxytocin increases itch sensitivity of mice in late pregnancy and its peripheral receptor mechanism of itch-promoting effect. Brain research bulletin. 2023-08-26. PMID:37633617. |
intradermal injection of oxytocin receptor (oxtr) or arginine vasopressin-1a receptor (avpr1a) antagonist did not affect histamine-induced scratching behavior, but both reversed the increase of itch sensitivity in late pregnant mice or the facilitated itch sensitivity by oxt. |
2023-08-26 |
2023-09-07 |
mouse |
| Sareh Pandamooz, Mohammad Saied Salehi, Benjamin Jurek, Carl-Philipp Meinung, Negar Azarpira, Mehdi Dianatpour, Inga D Neuman. Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders. Stem cell reviews and reports. 2023-08-07. PMID:37548806. |
the expression of oxytocin receptors (oxtr) was evaluated in these cells. |
2023-08-07 |
2023-08-14 |
human |
| Emmeline R I Howarth, Isabelle D Szott, Claire L Witham, Craig S Wilding, Emily J Bethel. Genetic polymorphisms in the serotonin, dopamine and opioid pathways influence social attention in rhesus macaques (Macaca mulatta). PloS one. vol 18. issue 8. 2023-08-02. PMID:37531334. |
for four loci the variants genotyped were length polymorphisms (slc6a4 5-hydroxytryptamine transporter length-polymorphic repeat (5-httlpr), slc6a4 stin polymorphism, tryptophan 5-hydroxylase 2 (tph2) and monoamine oxidase a (maoa)) whilst for the other five (5-hydroxytryptamine receptor 2a (htr2a), dopamine receptor d4 (drd4), oxytocin receptor (oxtr), arginine vasopressin receptor 1a (avpr1a), opioid receptor mu(μ) 1 (oprm1)) snps were analysed. |
2023-08-02 |
2023-08-14 |
monkey |
| Guanghui Shen, Shizhuo Yang, Liujun Wu, Yingjie Chen, Yueling Hu, Fan Zhou, Wei Wang, Peining Liu, Fenzan Wu, Yanlong Liu, Fan Wang, Li Che. The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders. Frontiers in psychiatry. vol 14. 2023-07-31. PMID:37520225. |
oxtr, the oxytocin receptor, may also be a promising candidate for treating alcohol withdrawal symptoms. |
2023-07-31 |
2023-08-14 |
Not clear |
| Svenja Müller, Maurizio Sicorello, Dirk Moser, Leonard Frach, Alicia Limberg, Anja M Gumpp, Laura Ramo-Fernandez, Franziska Köhler-Dauner, Jörg M Fegert, Christiane Waller, Robert Kumsta, Iris-Tatjana Kolass. The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity. Translational psychiatry. vol 13. issue 1. 2023-07-21. PMID:37479681. |
the dna methylation landscape of the human oxytocin receptor gene (oxtr): data-driven clusters and their relation to gene expression and childhood adversity. |
2023-07-21 |
2023-08-14 |
human |
| Svenja Müller, Maurizio Sicorello, Dirk Moser, Leonard Frach, Alicia Limberg, Anja M Gumpp, Laura Ramo-Fernandez, Franziska Köhler-Dauner, Jörg M Fegert, Christiane Waller, Robert Kumsta, Iris-Tatjana Kolass. The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity. Translational psychiatry. vol 13. issue 1. 2023-07-21. PMID:37479681. |
the oxytocin receptor gene (oxtr) is of interest when investigating the effects of early adversity on dna methylation. |
2023-07-21 |
2023-08-14 |
human |
| Feiye Wu, Jing Zhu, Yang Wan, Subinuer Kurexi, Jia Zhou, Ke Wang, Tongyu Che. Electroacupuncture Ameliorates Hypothalamic‒Pituitary‒Adrenal Axis Dysfunction Induced by Surgical Trauma in Mice Through the Hypothalamic Oxytocin System. Neurochemical research. 2023-07-12. PMID:37436613. |
moreover, ea treatment reversed the ht-induced downregulation of oxytocin (oxt) and oxytocin receptor (oxtr) in the hypothalamus. |
2023-07-12 |
2023-08-14 |
mouse |
| Margaux Evenepoel, Matthijs Moerkerke, Nicky Daniels, Viktoria Chubar, Stephan Claes, Jonathan Turner, Bart Vanaudenaerde, Lynn Willems, Johan Verhaeghe, Jellina Prinsen, Jean Steyaert, Bart Boets, Kaat Alaert. Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation. Translational psychiatry. vol 13. issue 1. 2023-06-30. PMID:37391413. |
here, salivary oxytocin was examined in the morning (am) and afternoon (pm) in school-aged children with (n = 80) and without (n = 40) asd (boys/girls 4/1), and also characterizations of dna methylation (dnam) of the oxytocin receptor gene (oxtr) were obtained. |
2023-06-30 |
2023-08-14 |
Not clear |
| Margaux Evenepoel, Matthijs Moerkerke, Nicky Daniels, Viktoria Chubar, Stephan Claes, Jonathan Turner, Bart Vanaudenaerde, Lynn Willems, Johan Verhaeghe, Jellina Prinsen, Jean Steyaert, Bart Boets, Kaat Alaert. Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation. Translational psychiatry. vol 13. issue 1. 2023-06-30. PMID:37391413. |
in control children, a notable association between oxtr methylation and levels of cortisol at pm was evident, likely indicative of a compensatory downregulation of oxtr methylation (higher oxytocin receptor expression) in children with heightened hpa axis activity. |
2023-06-30 |
2023-08-14 |
Not clear |