| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanaz Askari, Saba Mokhtari, Seyed Vahid Shariat, Behnam Shariati, Masoomeh Yarahmadi, Mohammadreza Shalbafa. Memantine augmentation of sertraline in the treatment of symptoms and executive function among patients with obsessive-compulsive disorder: A double-blind placebo-controlled, randomized clinical trial. BMC psychiatry. vol 22. issue 1. 2022-01-13. PMID:35022014. |
our main objective was to investigate the effectiveness of memantine, a non-competitive n-methyl-d-aspartate (nmda) receptor antagonist, as an adjunct therapy to sertraline, a selective serotonin reuptake inhibitor (ssri), to improve severity of symptoms and executive function among patients with obsessive-compulsive disorder. |
2022-01-13 |
2023-08-13 |
Not clear |
| Hikari Hatakama, Nozomi Asaoka, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kanek. A selective serotonin reuptake inhibitor ameliorates obsessive-compulsive disorder-like perseverative behavior by attenuating 5-HT Neuropharmacology. 2021-12-18. PMID:34921828. |
a selective serotonin reuptake inhibitor ameliorates obsessive-compulsive disorder-like perseverative behavior by attenuating 5-ht perseveration is a characteristic of patients with obsessive-compulsive disorder (ocd). |
2021-12-18 |
2023-08-13 |
Not clear |
| Markus Ponleitner, Daniel Szöllösi, Ali El-Kasaby, Florian Koban, Michael Freissmuth, Thomas Stockne. Molecular pharmacology. 2021-12-06. PMID:34866045. |
the serotonin transporter (sert/slc6a4) is an important drug target in the treatment of depression, anxiety and obsessive-compulsive disorders and - with structural information in several conformational states - one of the best understood transporters. |
2021-12-06 |
2023-08-13 |
human |
| Natasha Bhalla, Michael H Cha. Update on Management of the Oral and Maxillofacial Surgery Patient on Selective Serotonin Reuptake Inhibitors. Oral and maxillofacial surgery clinics of North America. vol 34. issue 1. 2021-11-23. PMID:34600797. |
selective serotonin reuptake inhibitors (ssris) have been the cornerstone for the treatment of depression, anxiety, obsessive-compulsive disorder, and panic disorder for a wide spectrum of age groups. |
2021-11-23 |
2023-08-13 |
Not clear |
| Michael Poyurovsky, Abraham Weizma. Quetiapine for Bipolar Depressive Episode in Obsessive-Compulsive Disorder Patients Maintained on Selective Serotonin Reuptake Inhibitor Treatment. Clinical neuropharmacology. vol 44. issue 4. 2021-10-25. PMID:33811191. |
quetiapine for bipolar depressive episode in obsessive-compulsive disorder patients maintained on selective serotonin reuptake inhibitor treatment. |
2021-10-25 |
2023-08-13 |
Not clear |
| Helen B Simpson, Edna B Foa, Michael G Wheaton, Thea Gallagher, Marina Gershkovich, Andrew B Schmidt, Jonathan D Huppert, Raphael B Campeas, Patricia A Imms, Shawn P Cahill, Christina DiChiara, Steven D Tsao, Anthony C Puliafico, Daniel Chazin, Anu Asnaani, Kelly Moore, Jeremy Tyler, Shari A Steinman, Arturo Sanchez-LaCay, Sandy Capaldi, Ivar Snorrason, Elizabeth Turk-Karan, Donna Vermes, Eyal Kalanthroff, Anthony Pinto, Chang-Gyu Hahn, Bin Xu, Page E Van Meter, Martha Katechis, Jennifer Scodes, Yuanjia Wan. Maximizing remission from cognitive-behavioral therapy in medicated adults with obsessive-compulsive disorder. Behaviour research and therapy. vol 143. 2021-10-25. PMID:34089924. |
practice guidelines for adults with obsessive-compulsive disorder (ocd) recommend augmenting serotonin reuptake inhibitors (sris) with exposure and ritual prevention (ex/rp). |
2021-10-25 |
2023-08-13 |
human |
| Shabir Ahmad Dar, Rayees Ahmad Wani, Inaamul Ha. A Comparative Study of Aripiprazole, Olanzapine, and L-Methylfolate Augmentation in Treatment Resistant Obsessive-Compulsive Disorder. The Psychiatric quarterly. vol 92. issue 4. 2021-10-22. PMID:33830427. |
about half of the patients with obsessive-compulsive disorder (ocd) do not respond to serotonin reuptake inhibitors (sris) or have a partial improvement in their symptoms. |
2021-10-22 |
2023-08-13 |
Not clear |
| Wendi E Marien, Eric A Storch, Gary R Geffken, Tanya K Murph. Intensive Family-Based Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder: Applications for Treatment of Medication Partial- or Nonresponders. Cognitive and behavioral practice. vol 16. issue 3. 2021-10-21. PMID:24174866. |
serotonin reuptake inhibitor medications and cognitive-behavioral therapy (cbt) are both effective treatments for pediatric obsessive-compulsive disorder (ocd). |
2021-10-21 |
2023-08-12 |
human |
| Joseph F McGuire, Adam B Lewin, Daniel A Geller, Ashley Brown, Kesley Ramsey, Jane Mutch, Andrew Mittelman, Jamie Micco, Cary Jordan, Sabine Wilhelm, Tanya K Murphy, Brent J Small, Eric A Storc. Advances in the treatment of pediatric obsessive-compulsive d-cycloserine with exposure and response prevention. Neuropsychiatry. vol 2. issue 4. 2021-10-21. PMID:24174993. |
exposure-based cognitive-behavioral therapy and serotonin reuptake inhibitor medications are efficacious treatment options for the management of pediatric obsessive-compulsive disorder. |
2021-10-21 |
2023-08-12 |
Not clear |
| Jiao Xu, Qinjian Hao, Ruiyi Qian, Xingyu Mu, Minhan Dai, Yulu Wu, Yiguo Tang, Min Xie, Qiang Wan. Optimal Dose of Serotonin Reuptake Inhibitors for Obsessive-Compulsive Disorder in Adults: A Systematic Review and Dose-Response Meta-Analysis. Frontiers in psychiatry. vol 12. 2021-10-12. PMID:34630180. |
optimal dose of serotonin reuptake inhibitors for obsessive-compulsive disorder in adults: a systematic review and dose-response meta-analysis. |
2021-10-12 |
2023-08-13 |
Not clear |
| Giuseppe Di Giovanni, Philippe De Deurwaerdèr. Serotonin research: Crossing scales and boundaries. Neuropharmacology. vol 181. 2021-09-23. PMID:33007358. |
modulation of serotonin transmission is considered in numerous central nervous system (cns) diseases including depression, anxiety, schizophrenia, obsessive-compulsive disorders, addiction, parkinson's disease, and alzheimer's disease. |
2021-09-23 |
2023-08-13 |
Not clear |
| Sanne Jensen, Davíð R M A Højgaard, Katja A Hybel, Erik Lykke Mortensen, Gudmundur Skarphedinsson, Karin Melin, Tord Ivarsson, Judith Becker Nissen, Bernhard Weidle, Robert Valderhaug, Nor Christian Torp, Kitty Dahl, Scott Compton, Per Hove Thomse. Distinct trajectories of long-term symptom severity in pediatric obsessive-compulsive disorder during and after stepped-care treatment. Journal of child psychology and psychiatry, and allied disciplines. vol 61. issue 9. 2021-09-20. PMID:31736082. |
first-line treatments for pediatric obsessive-compulsive disorder (ocd) include exposure-based cognitive-behavioral therapy (cbt) and selective serotonin reuptake inhibitors (ssris). |
2021-09-20 |
2023-08-13 |
Not clear |
| Janet Best, William Duncan, Farrah Sadre-Marandi, Parastoo Hashemi, H Frederik Nijhout, Michael Ree. Autoreceptor control of serotonin dynamics. BMC neuroscience. vol 21. issue 1. 2021-09-02. PMID:32967609. |
serotonin is a neurotransmitter that has been linked to a wide variety of behaviors including feeding and body-weight regulation, social hierarchies, aggression and suicidality, obsessive compulsive disorder, alcoholism, anxiety, and affective disorders. |
2021-09-02 |
2023-08-13 |
human |
| Richa Shukla, Sujita Kumar Ka. Comments on "Naturalistic outcome of medication-naïve obsessive-compulsive disorder treated with serotonin reuptake inhibitors". Asian journal of psychiatry. vol 62. 2021-08-20. PMID:34116368. |
comments on "naturalistic outcome of medication-naïve obsessive-compulsive disorder treated with serotonin reuptake inhibitors". |
2021-08-20 |
2023-08-13 |
Not clear |
| Srinivas Balachander, Aakash Bajaj, Nandita Hazari, Ajay Kumar, Nitin Anand, M Manjula, Paulomi M Sudhir, Anish V Cherian, Janardhanan C Narayanaswamy, T S Jaisoorya, Suresh Bada Math, Thennarasu Kandavel, Shyam Sundar Arumugham, Y C Janardhan Redd. Long-term Outcomes of Intensive Inpatient Care for Severe, Resistant Obsessive-Compulsive Disorder: Résultats à long terme de soins intensifs à des patients hospitalisés pour un trouble obsessionnel-compulsif grave et résistant. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 65. issue 11. 2021-08-18. PMID:32452212. |
a substantial proportion of severely ill patients with obsessive-compulsive disorder (ocd) do not respond to serotonin reuptake inhibitors (sris) and are unable to practice cognitive behavioral therapy (cbt) on an out-patient basis. |
2021-08-18 |
2023-08-13 |
Not clear |
| Gwyneth Za. Pharmacogenetics of Obsessive-Compulsive Disorder: An Evidence-Update. Current topics in behavioral neurosciences. vol 49. 2021-07-22. PMID:33550565. |
obsessive-compulsive disorder (ocd) is one such chronic and often debilitating mental illness with significant non-response to even the first-line medication, serotonin reuptake inhibitors. |
2021-07-22 |
2023-08-13 |
Not clear |
| A Merchán, C Pérez-Fernández, M J López, J Moreno, M Moreno, F Sánchez-Santed, P Flore. Dietary tryptophan depletion alters the faecal bacterial community structure of compulsive drinker rats in schedule-induced polydipsia. Physiology & behavior. vol 233. 2021-06-25. PMID:33577871. |
compulsive behaviour, present in different psychiatric disorders such as obsessive-compulsive disorder, schizophrenia and drug abuse, is associated with altered levels of serotonin (5-hydroxytryptamine, 5-ht). |
2021-06-25 |
2023-08-13 |
rat |
| Samantha E Stilley, Randy D Blakel. Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse. Frontiers in cellular neuroscience. vol 15. 2021-06-22. PMID:34149362. |
altered structure, expression, and regulation of the presynaptic serotonin (5-ht) transporter (sert) have been associated with multiple neurobehavioral disorders, including mood disorders, obsessive-compulsive disorder (ocd), and autism spectrum disorder (asd). |
2021-06-22 |
2023-08-13 |
mouse |
| Abel Thamby, Srinivas Balachander, Syed Farooq Ali, Shyam Sundar Arumugham, Jaisoorya Ts, Janardhanan C Narayanaswamy, Y C Janardhan Redd. Naturalistic outcome of medication-naïve obsessive compulsive disorder treated with serotonin reuptake inhibitors. Asian journal of psychiatry. vol 60. 2021-06-21. PMID:33930709. |
naturalistic outcome of medication-naïve obsessive compulsive disorder treated with serotonin reuptake inhibitors. |
2021-06-21 |
2023-08-13 |
Not clear |
| Mark M Gergues, Christine N Yohn, Anusha Bharadia, Marjorie R Levinstein, Benjamin Adam Samuel. Dentate gyrus activin signaling mediates the antidepressant response. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414389. |
antidepressants that target monoaminergic systems, such as selective serotonin reuptake inhibitors (ssris), are widely used to treat neuropsychiatric disorders including major depressive disorder, several anxiety disorders, and obsessive-compulsive disorder. |
2021-06-18 |
2023-08-13 |
mouse |