All Relations between serotonin and 5-ht receptor 1a

Reference Sentence Publish Date Extraction Date Species
Akihiro Hasumi, Hideyuki Maed. Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish: a comparative study with a dopamine activating drug. Journal of cannabis research vol 5 issue 1 2023 36871008 recent behavioral studies in rats have reported that cbd mediates serotonin (5-ht1a) receptor action to improve motor dysfunction induced by dopamine (d2) receptor blockade. 2023-03-04 2023-03-06 rat
Nuh Mehmet Bozkurt, Gokhan Una. Vortioxetine Improved Negative and Cognitive Symptoms of Schizophrenia in Subchronic MK-801 Induced Schizophrenia Model in Rats. Behavioural brain research vol issue 2023 36858318 vortioxetine is a new multimodal antidepressant with 5-ht1a agonism, 5-ht1b partial agonism, 5-ht3, 5-ht7, and 5-ht1d antagonism, and serotonin reuptake inhibition. 2023-03-01 2023-03-06 rat
David B Finlay, Warwick Mackie, Hunter D J Webb, Lucy R Thomsen, Mhairi Nimick, Rhonda J Rosengren, Julie A Marusich, Michelle Glass, Jenny L Wile. The piperazine analogue para-fluorophenylpiperazine alters timing of the physiological effects of the synthetic cannabinoid receptor agonist AMB-FUBINACA, without changing its discriminative stimulus, signalling effects, or metabolism. Pharmacology, biochemistry, and behavior vol issue 2023 36805861 a characteristic of amb-fubinaca use in new zealand has included the observation that forensic samples (from autopsies) and drugs seized by police have often been found to contain para-fluorophenylpiperazine (pfpp), a relatively little-characterised piperazine analogue that has been suggested to act through 5ht1a serotonin receptors. 2023-02-22 2023-03-06 rat
Ragini, Sakshi, Ashok Saini, Indra Man. Endocytosis and signaling of 5-HT1A receptor. Progress in molecular biology and translational science vol 196 issue 2023 36813354 5-ht binds to its receptor 5-ht1a to initiate gtp exchange at the gi/o protein, which activates the receptor g protein complex. 2023-02-22 2023-03-06 Not clear
Pattath Narayanan Suresh Kumar, Rohith Suresh, Vikas Meno. An Open-Label Rater-Blinded Randomized Trial of Vilazodone versus Escitalopram in Major Depression. Indian journal of psychological medicine vol 45 issue 1 2023 36778613 vilazodone, a novel selective serotonin reuptake inhibitor and 5-ht1a partial agonist, was approved in 2011 for treatment for major depression. 2023-02-13 2023-03-06 Not clear
Jelena Nikoli\\xc4\\x87, Katarina Vukojevi\\xc4\\x87, Violeta \\xc5\\xa0olji\\xc4\\x87, Josip Mi\\xc5\\xa1kovi\\xc4\\x87, Martina Orlovi\\xc4\\x87 Vlaho, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development. International journal of molecular sciences vol 24 issue 3 2023 36769290 expression patterns of serotonin receptors 5-ht1a, 5-ht2a, and 5-ht3a during human fetal lung development. 2023-02-11 2023-03-06 human
Jelena Nikoli\\xc4\\x87, Katarina Vukojevi\\xc4\\x87, Violeta \\xc5\\xa0olji\\xc4\\x87, Josip Mi\\xc5\\xa1kovi\\xc4\\x87, Martina Orlovi\\xc4\\x87 Vlaho, Mirna Saraga-Babi\\xc4\\x87, Natalija Filipovi\\xc4\\x8. Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development. International journal of molecular sciences vol 24 issue 3 2023 36769290 we analyzed the expression of the serotonin receptors 5-ht1a, 5-ht2a, and 5-ht3a at four different stages of fetal lung development from 12 to 40 weeks of gestation, divided into four groups: the pseudoglandular stage (12-16th week of development; 2023-02-11 2023-03-06 human
Ching-Yi Lin, Kevin Li, Rajaa Thalluri, Yu-Shang Le. Upregulated 5-HT1A receptor regulation of lower urinary tract function in rats following complete spinal cord injury. Journal of neurotrauma vol issue 2023 36762948 here, we investigate the expression levels of the serotonin 1a (5-ht1a) receptor in segments both rostral and caudal to the injured site, as well as the effects of blocking 5-ht1a receptor on micturition using pharmacological interventions in spinally-intact rats or t8 complete sci rats. 2023-02-10 2023-03-06 rat
Jiajia Dai, Hyangin Kim, Zerong You, Michael F McCabe, Shuzhuo Zhang, Shiyu Wang, Grewo Lim, Lucy Chen, Jianren Ma. Role of 5-HT1A-mediated upregulation of brain indoleamine 2,3 dioxygenase 1 in the reduced antidepressant and antihyperalgesic effects of fluoxetine during maintenance treatment. Frontiers in pharmacology vol 13 issue 2023 36588734 fluoxetine exposure induced upregulation of the 5-hydroxytryptamine 1a (5-ht1a) auto-receptor and indoleamine 2,3 dioxygenase 1 (ido1, a rate-limiting enzyme of tryptophan metabolism) in the brainstem dorsal raphe nucleus (drn), which shifted the tryptophan metabolism away from the 5-ht biosynthesis. 2023-01-02 2023-01-30 Not clear
Jo\\xc3\\xa3o P F Kurita, Anderson H F F Le\\xc3\\xa3o, Vinicius S Bioni, Raphael Wuo-Silva, Alvaro C Lima, Murilo A Paiva-Santos, Gabriela F Marinho, D\\xc3\\xa9bora M G Cunha, Marcela Becegato, Leonardo B Lopes-Silva, Alessandra M Ribeiro, Regina H Silv. Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala. Behavioral neuroscience vol issue 2022 36548050 the results showed that an increase in serotonin (5-ht) availability or the blockade of 5ht1a and 5ht2a bla receptors impaired aversive memory formation. 2022-12-22 2023-01-30 rat
Martin Kubitschke, Monika M\\xc3\\xbcller, Lutz Wallhorn, Mauro Pulin, Manuel Mittag, Stefan Pollok, Tim Ziebarth, Svenja Bremshey, Jill Gerdey, Kristin Carolin Claussen, Kim Renken, Juliana Gro\\xc3\\x9f, Pascal Gnei\\xc3\\x9fe, Niklas Meyer, J Simon Wiegert, Andreas Reiner, Martin Fuhrmann, Olivia Andrea Massec. Next generation genetically encoded fluorescent sensors for serotonin. Nature communications vol 13 issue 1 2022 36473867 we developed a family of genetically encoded serotonin (5-ht) sensors (sdarken) on the basis of the native 5-ht1a receptor and circularly permuted gfp. 2022-12-06 2023-01-30 Not clear
Carla V Arga\\xc3\\xb1araz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England) vol issue 2022 36458556 this refinement of drn inputs is not accompanied by changes in 5-ht1a receptor-mediated inhibition over 5-ht neurons. 2022-12-02 2023-01-30 mouse
Jeanette Tour, Angelica Sandstr\\xc3\\xb6m, Diana Kadetoff, Martin Schalling, Eva Kose. The OPRM1 gene and interactions with the 5-HT1a gene regulate conditioned pain modulation in fibromyalgia patients and healthy controls. PloS one vol 17 issue 11 2022 36342939 all subjects were genotyped for relevant functional polymorphisms in the genes coding for the \xce\xbc-opioid receptor (oprm1, rs1799971), the serotonin transporter (5-htt, 5-httlpr/rs25531) and the serotonin 1a receptor (5-ht1a, rs6295). 2022-11-07 2023-01-30 human
Ho-Geun Kang, Hee-Yun Kim, Hyunwoo Jee, Hwanseok Jun, Hosong Cho, Dongjun Park, Hyun-Jong Ahn, Hyung-Min Kim, Hyun-Ja Jeon. Compound of Cynanchum wilfordii and Humulus lupulus L. Ameliorates Menopausal Symptoms in Ovariectomized Mice. Reproductive sciences (Thousand Oaks, Calif.) vol issue 2022 36333646 values for hypothalamic serotonin (5-ht), dopamine, norepinephrine, estrogen receptor (er)-\xce\xb2, 5-ht1a, and 5-ht2a were significantly enhanced, while value for hypothalamic monoamine oxidase a was reduced in cwhl and caudatin groups compared with the ovx group. 2022-11-05 2023-01-30 mouse
Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimar\\xc3\\xa3es, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology vol issue 2022 36334768 in subsequent experiments, we investigated the estrous cycle effects and the contribution of dorsal hippocampus (dh) serotonin 1a (5-ht1a) and cannabinoid types 1 (cb1) and 2 (cb2) receptors to cbd-induced effects on memory retrieval/expression. 2022-11-05 2023-01-30 rat
Ria Gupta, Sidharth Mehan, Swesha Chhabra, Aditi Giri, Kajal Sherawa. Role of Sonic Hedgehog Signaling Activation in the Prevention of Neurological Abnormalities Associated with Obsessive-Compulsive Disorder. Neurotoxicity research vol issue 2022 36272053 abbreviation: foxa2: forkhead box; gata: globin transcription factor; lmx1b: lim homeobox transcription factor 1 beta; tph2: tryptophan hydroxylase 2; htr1a: serotonin receptor 1a; htr1b: serotonin receptor 1b; sert: serotonin transporter; vmat: vesicular monoamine transporter; mao: monoamine oxidase. 2022-10-22 2023-01-30 Not clear
Arnauld Belmer, Ronan Depoortere, Kate Beecher, Adrian Newman-Tancredi, Selena E Bartlet. Neural serotonergic circuits for controlling long-term voluntary alcohol consumption in mice. Molecular psychiatry vol issue 2022 36195637 we have previously shown using the "drinking-in-the-dark" model in mice that the stimulation of the serotonin receptor 1a (5-ht 2022-10-04 2023-01-30 mouse
Bernardo Lopez-Torres, Irma Ares, Marta Mart\\xc3\\xadnez, Jorge-Enrique Maximiliano, Mar\\xc3\\xada-Rosa Mart\\xc3\\xadnez-Larra\\xc3\\xb1aga, Arturo Anad\\xc3\\xb3n, Mar\\xc3\\xada-Ar\\xc3\\xa1nzazu Mart\\xc3\\xadne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association vol issue 2022 36126889 this research study also showed in hippocampus and prefrontal cortex, that lambda-cyhalothrin modified the mrna levels of da transporter gene (dat1 up-regulation), 5-ht transporter gene (sert down-regulation), da receptor genes (drd1and drd2 down-regulation), 5-ht receptor genes (5-ht1a and 5-ht2a down-regulation/up-regulation), da synthesis gene (th down-regulation), 5-ht synthesis gene (tph2 down-regulation), da and 5-ht degradation genes (maoa and maob up-regulation). 2022-09-20 2023-01-30 rat
Doo Ri Park, Chang Hwan Yeo, Jee Eun Yoon, Eun Young Hong, Bo Ram Choi, Yoon Jae Lee, In-Hyuk H. Polygonatum sibiricum improves menopause symptoms by regulating hormone receptor balance in an ovariectomized mouse model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 153 issue 2022 36076523 ps restored vaginal epithelium thickness, by increasing the expression of estrogen receptors er\xce\xb1 (esr1) and er\xce\xb2 (esr2), and increased serotonin concentration by reducing serotonin receptor 1\xc2\xa0a (5-ht1a) and glucocorticoid receptor (gr) expression. 2022-09-09 2023-01-30 mouse
Andr\\xc3\\xa9a V Maglione, Bruna P P do Nascimento, Miriam O Ribeiro, Talytha J L de Souza, Renata E C da Silva, Monica A Sato, Carlos A A Penatti, Luiz R G Britto, Janaina S de Souza, Rui M B Maciel, Rodrigo Rodrigues da Concei\\xc3\\xa7\\xc3\\xa3o, Roberto Laureano-Melo, Gisele Giannocc. Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease. Metabolic brain disease vol issue 2022 35951206 when compared to control hippocampal samples, the t3 group exhibited attenuated glycogen synthase kinase-3 (gsk3), metalloproteinase 10 (adam10), amyloid-beta precursor-protein (app), serotonin transporter (sert), 5ht1a receptor, monocarboxylate transporter 8 (mct8) and bone morphogenetic protein 7 (bmp-7) gene expression, whereas augmented superoxide dismutase 2 (sod2) and hairless gene expression. 2022-08-11 2023-01-30 mouse