| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara A Hosny, Alshaymaa M Abdelmenem, Taha Azouz, Samaa S Kamar, Asmaa M ShamsEldeen, Asmaa A El-Shafe. Beneficial Effect of Erythropoietin on Ameliorating Propionic Acid-Induced Autistic-Like Features in Young Rats. Acta histochemica et cytochemica. vol 56. issue 5. 2023-11-16. PMID:37970239. |
specimens from the cerebellar hemispheres were subjected to histological and ultrastructure examination, immunohistochemistry for glial fibrillary acidic protein (gfap) and calbindin-d28k, and biochemical analysis for glutathione peroxidase (gsh-px), malondialdehyde (mda), gamma amino-butyric acid (gaba), and serotonin. |
2023-11-16 |
2023-11-20 |
rat |
| Jie Yang, Yunlong Zhang, Zhenbin Cai, Jianyu Zou, Shaojin Li, Guiqiang Miao, Hongsheng Lin, Xiaodong Zhao, Minghui Ta. Inhibition of spastin impairs motor function recovery after spinal cord injury. Brain research bulletin. 2023-11-02. PMID:37918696. |
inhibition of spastin exacerbated neurogenesis impairment, as demonstrated by neuronal nuclei antigen staining, the inflammatory response, as shown by iba-1 and gfap staining, and axonal regeneration impairment, as shown by 5-hydroxytryptamine staining. |
2023-11-02 |
2023-11-08 |
mouse |
| Guanlan Liu, Israr Khan, Yuxi Li, Yun Yang, Xuerui Lu, Yafei Wang, Junxiang Li, Chunjiang Zhan. Overcoming Anxiety Disorder by Probiotic Foods (Basel, Switzerland). vol 11. issue 22. 2023-03-08. PMID:36429192. |
lzu-j-tsl6 was able to effectively increase the gaba content in the mice hippocampus (p < 0.0001) and restore some markers related to anxiety such as brain-derived neurotrophic factor (bdnf), glial fibrillary acidic protein (gfap), and 5-hydroxytryptamine (5-ht). |
2023-03-08 |
2023-08-16 |
mouse |
| Juan Zhuang, Zheng-Jun Pan, Ying Qin, Hui Liang, Wen-Feng Zhang, Ze-Yu Sun, Han-Bo Sh. Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos. Environmental science and pollution research international. 2023-03-04. PMID:36869944. |
the results showed that bde-47 stimulated the production of dopamine and 5-hydroxytryptamine, but inhibited expression of nestin, gfap, gap43, and psd95 in 24 hpf embryos. |
2023-03-04 |
2023-08-14 |
zebrafish |
| Cai Zhang, Baiping Liu, Jodi Pawluski, Harry W M Steinbusch, U Kirthana Kunikullaya, Cai Son. The effect of chronic stress on behaviors, inflammation and lymphocyte subtypes in male and female rats. Behavioural brain research. 2022-11-22. PMID:36414104. |
results show that cums increased anhedonia and anxiety-like behaviors, along with increased serum corticosterone, hippocampal pro-inflammatory factors, cd11b, ifn-γ, il-6 and il-17, but decreased cd4, cd25, cd4/cd8 ratio, gfap, 5-hydroxytryptamine (5-ht) and ne concentrations, regardless of sex. |
2022-11-22 |
2023-08-14 |
rat |
| Shu-Yun Xiao, Yi-Jie Liu, Wang Lu, Zhong-Wei Sha, Che Xu, Zhi-Hua Yu, Shin-Da Le. Possible Neuropathology of Sleep Disturbance Linking to Alzheimer's Disease: Astrocytic and Microglial Roles. Frontiers in cellular neuroscience. vol 16. 2022-06-27. PMID:35755779. |
we proposed that possible astrocyte-mediated and microglia-mediated neuropathological changes of sleep disturbances linked to ad, such as astrocytic adenosinergic a1, a2, and a3 regulation; astrocytic dopamine and serotonin; astrocyte-mediated proinflammatory status (tnfα); sleep disturbance-attenuated microglial cx3cr1 and p2y12; microglial iba-1 and astrocytic glial fibrillary acidic protein (gfap); and microglia-mediated proinflammatory status (il-1b, il-6, il-10, and tnfα). |
2022-06-27 |
2023-08-14 |
Not clear |
| Yeyang Wang, Man Xiong, Mingsen Wang, Hongdong Chen, Wenjun Li, Xiaozhong Zho. Quercetin promotes locomotor function recovery and axonal regeneration through induction of autophagy after spinal cord injury. Clinical and experimental pharmacology & physiology. vol 48. issue 12. 2021-11-18. PMID:34407225. |
immunofluorescence staining revealed that que elevated 5-hydroxytryptamine (5-ht) positive nerve fibres and neurofilament-200 (nf-200) positive neurons, reduced glial fibrillary acidic protein (gfap) positive astrocytes. |
2021-11-18 |
2023-08-13 |
rat |
| Shanshan Liu, Qing Liu, Yanjie Ju, Lei Li. Downregulation of miR-383 reduces depression-like behavior through targeting Wnt family member 2 (Wnt2) in rats. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33927285. |
the expression levels of mirnas were detected by qrt-pcr, and the expression levels of wnt2, depression-impacted proteins (gfap, bdnf, creb), brain neurotransmitters (5-ht, ne, da) and apoptosis-related proteins (bax and bcl-2) were evaluated by qrt-pcr and western blot. |
2021-11-08 |
2023-08-13 |
rat |
| John A Maguire, Juan M Bilbao, Kaiman Kovacs, Lothar Resc. Hypothalamic neurocytoma with vasopressin immunoreactivity: Immunohistochemical and ultrastructural observations. Endocrine pathology. vol 3. issue 2. 2021-01-10. PMID:32138406. |
the neoplastic cells were immunoreactive for neuron-specific enolase (nse), synaptophysin, and vasopressin, and nonimmunoreactive for glial fibrillary acidic protein (gfap), vasoactive intestinal peptide (vip), bombesin, chromogranin, neurofilament, cytokeratins (high and low molecular weight), vimentin, s100 protein, somatostatin, β-endorphin, galactosamine, growth hormone-releasing hormone (grh), neurophysin, serotonin, adrenaline and noradrenaline, and corticotropin-releasing hormone (crh). |
2021-01-10 |
2023-08-13 |
Not clear |
| Abdelaati El Khiat, Lahcen Tamegart, Ahmed Draoui, Radouane El Fari, Souad Sellami, Hanane Rais, Omar El Hiba, Halima Gamran. Kinetic deterioration of short memory in rat with acute hepatic encephalopathy: Involvement of astroglial and neuronal dysfunctions. Behavioural brain research. vol 367. 2020-06-08. PMID:30928460. |
while for the behavioral study, we used t-maze test to assess short working memory using the percentage of alternation behavior, together with an immunohistochemical analysis of the glial fibrillary acidic protein (gfap) as the key marker of astrocytes in the hippocampus, as well as serotonin (5-ht) for 5-htergic neurons within the dorsal raphe nucleus (drn). |
2020-06-08 |
2023-08-13 |
rat |
| Melanie Alpaugh, Danny Galleguillos, Juan Forero, Luis Carlos Morales, Sebastian W Lackey, Preeti Kar, Alba Di Pardo, Andrew Holt, Bradley J Kerr, Kathryn G Todd, Glen B Baker, Karim Fouad, Simonetta Sipion. Disease-modifying effects of ganglioside GM1 in Huntington's disease models. EMBO molecular medicine. vol 9. issue 11. 2018-06-12. PMID:28993428. |
gm1 administration results in decreased levels of mutant huntingtin, the protein that causes hd, and in a wide array of beneficial effects that include changes in levels of darpp32, ferritin, iba1 and gfap, modulation of dopamine and serotonin metabolism, and restoration of normal levels of glutamate, gaba, l-ser and d-ser. |
2018-06-12 |
2023-08-13 |
mouse |
| Sonja Westerberg, Marie Hagbom, Anandi Rajan, Vesa Loitto, B David Persson, Annika Allard, Johan Nordgren, Sumit Sharma, Karl-Eric Magnusson, Niklas Arnberg, Lennart Svensso. Interaction of Human Enterochromaffin Cells with Human Enteric Adenovirus 41 Leads to Serotonin Release and Subsequent Activation of Enteric Glia Cells. Journal of virology. vol 92. issue 7. 2018-04-17. PMID:29367250. |
the egcs were also activated by serotonin alone, as shown in the significantly increased gfap staining intensity. |
2018-04-17 |
2023-08-13 |
human |
| Arnold Gutierrez, Sarah A Jablonski, Robyn M Amos-Kroohs, Anna C Barnes, Michael T Williams, Charles V Vorhee. Effects of Housing on Methamphetamine-Induced Neurotoxicity and Spatial Learning and Memory. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28287691. |
ma reduced dopamine (da) and serotonin (5-ht) in the neostriatum and nucleus accumbens, 5-ht in the hippocampus, and increased gfap in neostriatum and nucleus accumbens compared with saline controls. |
2018-01-30 |
2023-08-13 |
rat |
| Arnold Gutierrez, Sarah A Jablonski, Robyn M Amos-Kroohs, Anna C Barnes, Michael T Williams, Charles V Vorhee. Effects of Housing on Methamphetamine-Induced Neurotoxicity and Spatial Learning and Memory. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28287691. |
in neostriatum, barren-cage housing protected against ma-induced increases in gfap, but it did not prevent da and 5-ht reductions, although it did increase hippocampal norepinephrine. |
2018-01-30 |
2023-08-13 |
rat |
| Mahmoud M Said, Marwa M Abd Rab. Neuroprotective effects of eugenol against aluminiuminduced toxicity in the rat brain. Arhiv za higijenu rada i toksikologiju. vol 68. issue 1. 2017-11-08. PMID:28365674. |
on the other hand, co-administration of dietary eugenol with al intoxication restored brain bdnf (108.76±2.64 pg mg-1 protein) and 5-ht (2.13±0.27 ng mg-1 tissue) to normal levels, enhanced brain tas (13.43±0.24 μmol g-1 tissue, p<0.05), with a concomitant significant reduction in tnf-α (69.98±4.74 pg mg-1 protein) and casp-3 (3.80±0.37 ng mg-1 protein) levels (p<0.001), as well as ache activity (24.50±3.25 u mg-1 protein, p<0.001), and increased striatal gfap immunoreactivity, compared with al-treated rats. |
2017-11-08 |
2023-08-13 |
rat |
| Mei-Rong Chen, Ping Dai, Shu-Fen Wang, Shu-Hua Song, Hang-Ping Wang, Ya Zhao, Ting-Hua Wang, Jia Li. BDNF Overexpression Exhibited Bilateral Effect on Neural Behavior in SCT Mice Associated with AKT Signal Pathway. Neurochemical research. vol 41. issue 10. 2017-04-04. PMID:27278760. |
immunohistochemistry was employed to detect the location and the expression of bdnf, neun, 5-ht, gap-43, gfap as well as cgrp, and the level of p-akt and akt were examined through western blot analysis. |
2017-04-04 |
2023-08-13 |
mouse |
| b' Katalin Adrienna K\\xc3\\xa9kesi, G\\xc3\\xa1bor Juh\\xc3\\xa1sz, Attila Simor, P\\xc3\\xa9ter Guly\\xc3\\xa1ssy, Eva M\\xc3\\xb3nika Szeg\\xc5\\x91, Eva Hunyadi-Guly\\xc3\\xa1s, Zsuzsanna Darula, Katalin F Medzihradszky, Mikl\\xc3\\xb3s Palkovits, Botond Penke, Andr\\xc3\\xa1s Czurk\\xc3\\xb. Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide. PloS one. vol 7. issue 12. 2013-06-26. PMID:23272063.' |
we also pointed out 9 proteins that changed in both the amygdala and the cortex, and from these, gfap, ina, nefl, nefm and tuba1 are interacting cytoskeletal proteins that have a functional connection to glutamate, gaba, and serotonin receptors. |
2013-06-26 |
2023-08-12 |
Not clear |
| Ya-Yuan Fu, Shih-Jung Peng, Hsin-Yao Lin, Pankaj J Pasricha, Shiue-Cheng Tan. 3-D imaging and illustration of mouse intestinal neurovascular complex. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 1. 2013-02-20. PMID:23086917. |
the pan-neuronal marker pgp9.5, sympathetic neuronal marker tyrosine hydroxylase (th), serotonin, and glial markers s100b and gfap were used as the immunostaining targets of neural tissues. |
2013-02-20 |
2023-08-12 |
mouse |
| Donatella Marazziti, Stefano Baroni, Andrea Pirone, Gino Giannaccini, Laura Betti, Lara Schmid, Elena Vatteroni, Lionella Palego, Franco Borsini, Fabio Bordi, Ilaria Piano, Claudia Gargini, Maura Castagna, Mario Catena-Dell'osso, Antonio Lucacchin. Distribution of serotonin receptor of type 6 (5-HT₆) in human brain post-mortem. A pharmacology, autoradiography and immunohistochemistry study. Neurochemical research. vol 37. issue 5. 2012-08-20. PMID:22278721. |
the immunohistochemistry, carried out in the striatum only, coupled with the immunofluorescence with glial fibrillary acidic protein (gfap) and parvalbumin (pv) showed the co-localization of 5-ht(6) receptor with pv, while indicating that this receptor subtype was expressed in neurons and not in astrocytes. |
2012-08-20 |
2023-08-12 |
human |
| Ming Gu, Kan Miyoshi, Ronald Dubner, Wei Guo, Shiping Zou, Ke Ren, Koichi Noguchi, Feng We. Spinal 5-HT(3) receptor activation induces behavioral hypersensitivity via a neuronal-glial-neuronal signaling cascade. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 36. 2011-10-31. PMID:21900561. |
in addition, exogenous brain-derived neurotrophic factor-induced descending pain facilitation was accompanied by upregulation of cd11b and gfap expression in the spinal dorsal horn after microinjection in the rvm, and these events were significantly prevented by functional blockade of spinal 5-ht(3) receptors. |
2011-10-31 |
2023-08-12 |
rat |