| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Tagliaferro, A J Ramos, E M López, J Pecci Saavedra, A Brusc. Neural and astroglial effects of a chronic parachlorophenylalanine-induced serotonin synthesis inhibition. Molecular and chemical neuropathology. vol 32. issue 1-3. 1998-02-26. PMID:9437667. |
these observations indicated that astrocytes are sensitive to the 5ht level, and in presence of low 5ht concentration in the intercellular space, astrocytes could react by synthesizing glial proteins like gfap and s-100 protein. |
1998-02-26 |
2023-08-12 |
rat |
| G D Cappon, L L Morford, C V Vorhee. Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response. Brain research. Developmental brain research. vol 103. issue 2. 1998-02-18. PMID:9427479. |
methamphetamine (ma) administration to adult rats results in neurotoxicity characterized by depletion of caudate-putamen (cp) dopamine (da) and serotonin (5-ht) and an accompanying increase in glial fibrillary acidic protein (gfap) content. |
1998-02-18 |
2023-08-12 |
rat |
| Z Cai, H K Kimelber. Glutamate receptor-mediated calcium responses in acutely isolated hippocampal astrocytes. Glia. vol 21. issue 4. 1998-01-30. PMID:9419013. |
gfap(+) cells were acutely isolated from the hippocampi of 1-10 day old rats, and the intracellular calcium responses to l-glutamate, atp, and 5-ht were studied in single cells. |
1998-01-30 |
2023-08-12 |
rat |
| M B Lopes, H J Altermatt, B W Scheithauer, C W Shepherd, S R VandenBer. Immunohistochemical characterization of subependymal giant cell astrocytomas. Acta neuropathologica. vol 91. issue 4. 1996-11-27. PMID:8928613. |
immunoreactivity for glial fibrillary acidic protein (gfap) and/or s-100 protein was considered indicative of a glial phenotype, whereas the presence of neuronal differentiation was assessed by staining for cytoskeletal proteins [neurofilament epitopes, class iii beta-tubulin, microtubule-associated protein 2 (map2), synaptophysin], neurosecretory substances [serotonin, cholecystokinin, beta-endorphin, substance p, somatostatin, metenkephalin, neuropeptide y, vasoactive intestinal polypeptide (vip), and for the 28-kda neuron-associated calcium binding protein calbindin. |
1996-11-27 |
2023-08-12 |
Not clear |
| S Araneda, C Silva-Barrat, C Menini, R Naque. High expression of noradrenaline, choline acetyltransferase and glial fibrillary acidic protein in the epileptic focus consecutive to GABA withdrawal. An immunocytochemical study. Brain research. vol 655. issue 1-2. 1995-02-06. PMID:7812766. |
the aim of the present study was to determine, by immunocytochemistry, if neurotransmitters other than gaba are involved in gws, namely: noradrenaline (na), serotonin, choline acetyltransferase (cat), cholecystokinin, neuropeptide y, somatostatin and glial fibrillary acid protein (gfap). |
1995-02-06 |
2023-08-12 |
rat |
| C Bendotti, S Baldessari, M Pende, G Tarizzo, A Miari, M L Presti, T Mennini, R Samani. Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? Brain research bulletin. vol 34. issue 4. 1994-10-11. PMID:8082031. |
intracerebroventricularly (icv) injected 5,7-dihydroxytryptamine (5,7-dht), which reduced by 70-90% forebrain serotonin levels, significantly raised glial fibrillary acidic protein (gfap) mrna levels in the hippocampus and nucleus raphe dorsalis 5 days but not 15 days after the lesion. |
1994-10-11 |
2023-08-12 |
rat |
| C Bendotti, S Baldessari, M Pende, G Tarizzo, A Miari, M L Presti, T Mennini, R Samani. Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? Brain research bulletin. vol 34. issue 4. 1994-10-11. PMID:8082031. |
unlike the icv route, bilateral injection of 5,7-dht into the medial forebrain bundle, which caused a 65-90% reduction of serotonin levels in different forebrain regions, significantly raised gfap mrna and mbr binding only at the site of injection with no effect in hippocampus, striatum, and cortex. |
1994-10-11 |
2023-08-12 |
rat |
| C Bendotti, S Baldessari, M Pende, G Tarizzo, A Miari, M L Presti, T Mennini, R Samani. Does GFAP mRNA and mitochondrial benzodiazepine receptor binding detect serotonergic neuronal degeneration in rat? Brain research bulletin. vol 34. issue 4. 1994-10-11. PMID:8082031. |
high doses of d-fenfluramine (10 mg/kg intraperitoneally twice daily for 4 days) caused 80-90% reduction of serotonin levels 5 days after the last injection but did not change the gfap mrna or the mbr binding in any of the brain regions considered. |
1994-10-11 |
2023-08-12 |
rat |
| M A Wilson, M E Mollive. Microglial response to degeneration of serotonergic axon terminals. Glia. vol 11. issue 1. 1994-09-29. PMID:8070892. |
thus, degeneration of 5-ht axon terminals affects only a subset of the microglial markers examined; in comparison, retrograde reaction to facial nerve transection causes a robust increase in all of these markers and in gfap. |
1994-09-29 |
2023-08-12 |
rat |
| M A Wilson, M E Mollive. Microglial response to degeneration of serotonergic axon terminals. Glia. vol 11. issue 1. 1994-09-29. PMID:8070892. |
these findings indicate that cns microglia are activated by degeneration of fine, unmyelinated 5-ht axon terminals; furthermore, sensitive microglial markers can detect a subtle axonal lesion that provokes no detectable increase in gfap expression by astrocytes. |
1994-09-29 |
2023-08-12 |
rat |
| J P O'Callaghan, D B Mille. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071867. |
d-meth, d-mda and d-mdma also increased gfap in cortex, effects that were associated with small (10-25%) and transient decrements in cortical 5-ht. |
1994-09-28 |
2023-08-12 |
mouse |
| J P O'Callaghan, D B Mille. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071867. |
d-fen caused prolonged (weeks) decrements (20%) in cortical 5-ht but did not affect cortical gfap. |
1994-09-28 |
2023-08-12 |
mouse |
| V Dave, H K Kimelber. Na(+)-dependent, fluoxetine-sensitive serotonin uptake by astrocytes tissue-printed from rat cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 8. 1994-08-30. PMID:8046464. |
3h-5-ht uptake (0.3 microm 5-ht, 3.4 microci/ml) in both tissue-printed gfap(+) astrocytes and nf(+) structures was sensitive to 1 microm fluoxetine and was also na+ dependent. |
1994-08-30 |
2023-08-12 |
rat |
| C Fages, G Le Prince, M Didier-Bazes, B Rolland, H Hardin, M Tard. Long-term astroglial reaction to serotonergic fiber degeneration. Brain research. vol 639. issue 1. 1994-06-16. PMID:7910108. |
5ht injury stimulated gfap and gs expression in a temporally and regionally specific fashion. |
1994-06-16 |
2023-08-12 |
rat |
| S Ueda, X F Gu, P M Whitaker-Azmitia, I Naruse, E C Azmiti. Neuro-glial neurotrophic interaction in the S-100 beta retarded mutant mouse (Polydactyly Nagoya). I. Immunocytochemical and neurochemical studies. Brain research. vol 633. issue 1-2. 1994-04-25. PMID:7511035. |
in order to clarify the effects of the retarded production of s-100 beta on the development of monoaminergic neuronal systems and supporting glial cells, immunocytochemical studies of tyrosine hydroxylase (th), serotonin (5-ht), s-100 beta and glial fibrillary acidic protein (gfap). |
1994-04-25 |
2023-08-12 |
mouse |
| H S Sharma, Y Olsson, J Cervós-Navarr. p-Chlorophenylalanine, a serotonin synthesis inhibitor, reduces the response of glial fibrillary acidic protein induced by trauma to the spinal cord. An immunohistochemical investigation in the rat. Acta neuropathologica. vol 86. issue 5. 1994-03-14. PMID:8310791. |
the results indicate that serotonin influences the increase of gfap immunoreactivity following spinal cord injury either directly or indirectly, for instance by its microvascular reactions. |
1994-03-14 |
2023-08-12 |
rat |
| N E Rowland, A N Kalehua, B H Li, S L Semple-Rowland, W J Strei. Loss of serotonin uptake sites and immunoreactivity in rat cortex after dexfenfluramine occur without parallel glial cell reactions. Brain research. vol 624. issue 1-2. 1994-01-13. PMID:8252414. |
the frontal cortices of rats which received either d,l- or d-fenfluramine (dfen) for 4 days were examined 18 h to 2 weeks following treatment for changes in synaptosomal uptake of serotonin (5ht), paroxetine binding, 5ht-immunoreactivity (5ht-ir), and both astrocytic (gfap) and microglial markers. |
1994-01-13 |
2023-08-12 |
rat |
| J Pecci Saavedra, A Brusco, J J López-Costa, L A Gómez, E M Lópe. Antibodies as molecular probes in neurobiology. Identification of chemically defined neurons and synapses in tissues and tissue cultures. Molecular neurobiology. vol 6. issue 4. 1993-03-18. PMID:1285932. |
the differentiation of neurons and astrocytes was studied using antibodies to 5-ht and gfap. |
1993-03-18 |
2023-08-11 |
Not clear |
| B Lach, B W Scheithauer, A Gregor, M R Wic. Colloid cyst of the third ventricle. A comparative immunohistochemical study of neuraxis cysts and choroid plexus epithelium. Journal of neurosurgery. vol 78. issue 1. 1993-01-11. PMID:8416224. |
these lesions were examined for localization of the following antigens: cytokeratins, epithelial membrane antigen, secretory component, carcinoembryonic antigen, prealbumin, vimentin, glial fibrillary acidic protein (gfap), s-100 protein, neuron-specific enolase, 68-kd neurofilament protein, chromogranin, serotonin, and lysozyme, and with leu-7 monoclonal antibodies. |
1993-01-11 |
2023-08-12 |
Not clear |
| M Didier-Bazes, L Chouaf, H Hardin, M Aguera, B Voutsinos, M F Beli. Developmental neuron-glia interactions: role of serotonin innervation upon the differentiation of the ependymocytes of the rat subcommissural organ. Progress in brain research. vol 91. 1992-11-25. PMID:1410420. |
they possess particular phenotypic characteristics: they accumulate [3h]gaba by a specific uptake mechanism, contain transitory gfap during ontogenesis and do not express ps100; on the other hand they receive a 5ht input which forms typical synaptic contacts. |
1992-11-25 |
2023-08-11 |
mouse |