All Relations between serotonin and glutamatergic

Publication Sentence Publish Date Extraction Date Species
Boyang Li, Kunnian Ran, Zefan Jing, Wei Han, Xiaozhong Pen. Glioma induces atypical depression-like behaviors in mice through the 5-HT and glutamatergic synapse pathways. Biochemical and biophysical research communications. vol 704. 2024-03-03. PMID:38432144. glioma induces atypical depression-like behaviors in mice through the 5-ht and glutamatergic synapse pathways. 2024-03-03 2024-03-06 mouse
Boyang Li, Kunnian Ran, Zefan Jing, Wei Han, Xiaozhong Pen. Glioma induces atypical depression-like behaviors in mice through the 5-HT and glutamatergic synapse pathways. Biochemical and biophysical research communications. vol 704. 2024-03-03. PMID:38432144. our findings suggested that the presence of glioma caused and altered depression-like behaviors, which was potentially related to the 5-ht and glutamatergic synapse pathways. 2024-03-03 2024-03-06 mouse
Roberto Ogelman, Luis E Gomez Wulschner, Victoria M Hoelscher, In-Wook Hwang, Victoria N Chang, Won Chan O. Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex. Nature communications. vol 15. issue 1. 2024-02-16. PMID:38365905. 5-ht release on single spines induced structural and functional long-term potentiation (ltp), requiring both 5-ht2a and 5-ht7 receptor signals, in a glutamatergic activity-independent manner. 2024-02-16 2024-02-19 mouse
Jitendra Kumar Sinha, Anchal Trisal, Shampa Ghosh, Saurabh Gupta, Krishna Kumar Singh, Sung Soo Han, Madhumita Mahapatra, Mosleh Mohammad Abomughaid, Ali M Abomughayedh, Abdulmajeed G Almutary, Danish Iqbal, Rakesh Bhaskar, Abhishek Kumar Singh, Prabhu Chandra Mishra, Saurabh Kumar Jha, Niraj Kumar Jh. Psychedelics for Alzheimer's Disease-Related Dementia: Unveiling Therapeutic Possibilities and Pathways. Ageing research reviews. 2024-02-02. PMID:38307424. these compounds, which act as potent 5-hydroxytryptamine (5ht) agonists, have been recognized for their ability to enhance neural plasticity through the activation of the serotoninergic and glutamatergic systems. 2024-02-02 2024-02-05 Not clear
Đorđe Đorović, Vesna Lazarevic, Jovana Aranđelović, Vladimir Stevanović, Wojciech Paslawski, Xiaoqun Zhang, Milica Velimirović, Nataša Petronijević, Laslo Puškaš, Miroslav M Savić, Per Svenningsso. Maternal deprivation causes CaMKII downregulation and modulates glutamate, norepinephrine and serotonin in limbic brain areas in a rat model of single prolonged stress. Journal of affective disorders. 2024-01-10. PMID:38199412. an intricate relationship exists between various neurotransmitters (such as glutamate, norepinephrine or serotonin), calcium/calmodulin-dependent protein kinase ii (camkii), as an important regulator of glutamatergic synaptic function, and ptsd. 2024-01-10 2024-01-13 rat
Uwemedimo G Udoh, John R Bruno, Paige O Osborn, Kara G Prat. Serotonin strengthens a developing glutamatergic synapse through a PI3K-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-01-03. PMID:38169457. serotonin strengthens a developing glutamatergic synapse through a pi3k-dependent mechanism. 2024-01-03 2024-01-06 xenopus_laevis
Licia Vellucci, Mariateresa Ciccarelli, Elisabetta Filomena Buonaguro, Michele Fornaro, Giordano D'Urso, Giuseppe De Simone, Felice Iasevoli, Annarita Barone, Andrea de Bartolomei. The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia. Biomolecules. vol 13. issue 8. 2023-08-26. PMID:37627285. an integrative view exploring this topic should take into account the following aspects: (i) the implication for glutamate, dopamine, and serotonin neurotransmission as demonstrated by genetic findings; (ii) the growing neuroimaging evidence of the common brain regions and dysfunctional circuits involved in both diseases; (iii) the pharmacological modulation of dopaminergic, serotoninergic, and glutamatergic systems as current therapeutic strategies in schizophrenia ocs; (iv) the recent discovery of midbrain dopamine neurons and dopamine d1- and d2-like receptors as orchestrating hubs in repetitive and psychotic behaviors; (v) the contribution of n-methyl-d-aspartate receptor subunits to both psychosis and ocd neurobiology. 2023-08-26 2023-09-07 Not clear
Cam Ha Tran, Robert Renden, Adam Institoris, Kushal Sharm. Modulatory Effects of Noradrenergic and Serotonergic Signaling Pathway on Neurovascular Coupling. Research square. 2023-07-28. PMID:37502946. although the critical role of glutamatergic signaling in this process has been extensively investigated, the impact of behavioral state, and the release of behavior-associated neurotransmitters, such as norepinephrine and serotonin, on astrocyte ca2+ dynamics and functional hyperemia have received less attention. 2023-07-28 2023-08-14 mouse
Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). 2023-05-30 2023-08-14 Not clear
Jo Sourbron, Lieven Laga. Fenfluramine: a plethora of mechanisms? Frontiers in pharmacology. vol 14. 2023-05-30. PMID:37251322. our review highlights the importance of serotonin and sigma-1 receptor mechanisms in maintaining a balance between excitatory (glutamatergic) and inhibitory (γ-aminobutyric acid [gaba]-ergic) neural networks, and suggests that these mechanisms may represent primary pharmacological moas in seizures, non-seizure comorbidities, and sudep. 2023-05-30 2023-08-14 Not clear
Josua Zimmermann, Niklaus Zölch, Rebecca Coray, Francesco Bavato, Nicole Friedli, Markus R Baumgartner, Andrea E Steuer, Antje Opitz, Annett Werner, Georg Oeltzschner, Erich Seifritz, Ann Kathrin Stock, Christian Beste, David M Cole, Boris B Quedno. Chronic 3,4-Methylenedioxymethamphetamine (MDMA) use is related to glutamate and GABA concentrations in the striatum, but not in the anterior cingulate cortex. The international journal of neuropsychopharmacology. 2023-05-26. PMID:37235749. however, serotonin functions are strongly entangled with glutamate as well as γ-aminobutyric acid (gaba) neurotransmission and studies in mdma-exposed rats show long-term adaptations in glutamatergic and gabaergic signaling. 2023-05-26 2023-08-14 rat
Abdulla A-B Badawy, Shazia Dawood, Samina Ban. Kynurenine pathway of tryptophan metabolism in pathophysiology and therapy of major depressive disorder. World journal of psychiatry. vol 13. issue 4. 2023-05-01. PMID:37123095. the pathophysiology of mdd may be underpinned by both the serotonin deficiency and glutamatergic activation mediated respectively by tdo induction and n-methyl-d-aspartate receptor activation. 2023-05-01 2023-08-14 Not clear
Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. serotonin 5ht1a receptor (r) activation at the soma-dendritic level of serotonergic raphe neurons and glutamatergic hippocampal pyramidal neurons leads to a decrease in neuronal firing by activation of g protein-coupled inwardly-rectifying potassium (girk) channels. 2023-04-28 2023-08-14 rat
Richard Baskerville, Thomas McGrath, Lindy Castel. The effects of physical activity on glutamate neurotransmission in neuropsychiatric disorders. Frontiers in sports and active living. vol 5. 2023-03-23. PMID:36949894. there is therefore increasing interest in glutamatergic systems which offers new paradigms of understanding mechanisms connecting physical activity, stress, inflammation and depression, not explained by the serotonin theories of depression. 2023-03-23 2023-08-14 Not clear
Alireza Noori, Kousha Farhadi, Yasmin Mohtasham Kia, Nastaran Hosseini, Soraya Mehrab. Role of P11 through serotonergic and glutamatergic pathways in LID. Molecular biology reports. 2023-02-28. PMID:36853472. studies showed that metabotropic glutamate receptor 5 (mglur5) antagonists and 5-hydroxytryptamine receptor 1b (5ht1b) agonists significantly reduced lid when considering the glutamatergic overactivity and compensatory mechanisms of serotonergic neurons after l-dopa therapy. 2023-02-28 2023-08-14 Not clear
B Spurny-Dworak, M B Reed, P Handschuh, T Vanicek, M Spies, W Bogner, R Lanzenberge. The influence of season on glutamate and GABA levels in the healthy human brain investigated by magnetic resonance spectroscopy imaging. Human brain mapping. 2023-02-25. PMID:36840505. these modulatory neurotransmitters, such as serotonin, are influencing glutamatergic and gabaergic neurotransmission. 2023-02-25 2023-08-14 human
Chandan K Behera, Alok Joshi, Da-Hui Wang, Trevor Sharp, KongFatt Wong-Li. Degeneracy and stability in neural circuits of dopamine and serotonin neuromodulators: A theoretical consideration. Frontiers in computational neuroscience. vol 16. 2023-02-10. PMID:36761394. here, we address this by computationally modeling the neural circuits of neuromodulators serotonin and dopamine, local glutamatergic and gabaergic interneurons, and their possible interactions, under reward/punishment-based conditioning tasks. 2023-02-10 2023-08-14 Not clear
Hyun-A Oh, Jae Hong Yoo, Ye-Ji Kim, Kyung-Seok Han, Dong Ho Wo. 4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT Neurotoxicology. 2023-02-04. PMID:36738894. 4-ea-nbome, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-ht new psychoactive substances (npss) are compounds designed to mimic illegal recreational drugs. 2023-02-04 2023-08-14 mouse
Nuria Acero, Teresa Ortega, Victoria Villagrasa, Gemma Leon, Dolores Muñoz-Mingarro, Encarna Castillo, M Eugenia González-Rosende, Silvia Borrás, Jose Luis Rios, Francisco Bosch-Morell, Isabel Martínez-Solí. Phytotherapeutic alternatives for neurodegenerative dementias: Scientific review, discussion and therapeutic proposal. Phytotherapy research : PTR. 2023-01-23. PMID:36690605. there are preclinical and clinical scientific evidences on their properties against protein aggregates in the central nervous system and their effects on neuroinflammation, apoptosis dysregulation, mitochondrial dysfunction, gabaergic, glutamatergic and dopaminergic systems alterations, monoamine oxidase alterations, serotonin depletion and oestrogenic protection. 2023-01-23 2023-08-14 Not clear
Enrico Premi, Juergen Dukart, Irene Mattioli, Ilenia Libri, Marta Pengo, Yasmine Gadola, Maria Cotelli, Rosa Manenti, Giuliano Binetti, Stefano Gazzina, Antonella Alberici, Mauro Magoni, Giacomo Koch, Roberto Gasparotti, Alessandro Padovani, Barbara Borron. Unravelling neurotransmitters impairment in primary progressive aphasias. Human brain mapping. 2023-01-17. PMID:36649260. as compared to hc, voxel-based brain changes in ppa were significantly associated with spatial distribution of serotonin, dopamine, and glutamatergic pathways (p < .05, false discovery rate corrected-corrected). 2023-01-17 2023-08-14 Not clear