| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Mohammad Basatinya, Javad Sajedianfard, Saeed Nazifi, Saied Hosseinzade. The analgesic effects of insulin and its disorders in streptozotocin-induced short-term diabetes. Physiological reports. vol 12. issue 8. 2024-04-19. PMID:38639646. |
in diabetic rats, the levels of da, serotonin, and mgsh decreased in the nuclei of the thalamus, raphe magnus, and periaqueductal gray, and the levels of ros increased. |
2024-04-19 |
2024-04-21 |
rat |
| Yu-Long Zhao, Jia-Liang Xu, Hui-Yuan Yi, Sani Sa'idu Baba, Yi-Xiao Guo, Xue-Mei Hou, Xiao-Cui Yuan, Xu-Hui Li, Yu-Ying Wang, Ling-Li Liang, Fu-Quan Hu. Activation of 5-HT Neuropharmacology. 2023-12-31. PMID:38160874. |
activation of 5-ht the ventrolateral orbital cortex (vlo) is identified as an integral component of the endogenous analgesic system comprising a spinal cord - thalamic nucleus submedius - vlo - periaqueductal gray (pag) - spinal cord loop. |
2023-12-31 |
2024-01-05 |
Not clear |
| Zahra Gholami, Ava Soltani Hekmat, Ali Abasi, Kazem Javanmard. Alamandine injection in the periaqueductal gray and rostral ventromedial medulla attenuates allodynia induced by sciatic nerve ligation in rats. Neuroscience letters. 2023-11-26. PMID:38008350. |
this study aimed to investigate the effects of alamandine (10, 40, and 100 pmol) in a rat model of allodynia induced by sciatic nerve ligation, with a specific focus on examining the involvement of mrgd receptors, nmdar1, and serotonin transporter (sert) in the ventrolateral periaqueductal gray (vlpag) and rostral ventromedial medulla (rvm). |
2023-11-26 |
2023-11-28 |
rat |
| Carl L Faingold, Hua-Jun Fen. Response to Singh et al. 2023: It is premature for a unified hypothesis of sudden unexpected death in epilepsy: A great amount of research is still needed to understand the multisystem cascade. Epilepsia. vol 64. issue 9. 2023-09-19. PMID:37386865. |
however, we strongly believe the hypothesis is timely, because it is based on the continuing progress on sudep-related research on serotonin (5-ht) and adenosine as well as neuroanatomical findings.we propose testing of 5-ht enhancing drugs, neurotoxicity blocking drugs, such as n-methyl-d-aspartate (nmda) antagonists and periaqueductal gray (pag) electrical stimulation for sudep prevention. |
2023-09-19 |
2023-10-07 |
mouse |
| Carl L Faingold, Hua-Jun Fen. A unified hypothesis of SUDEP: Seizure-induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqueductal gray. Epilepsia. 2023-01-30. PMID:36715572. |
a unified hypothesis of sudep: seizure-induced respiratory depression induced by adenosine may lead to sudep but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqueductal gray. |
2023-01-30 |
2023-08-14 |
human |
| Olivia J Hon, Jeffrey F DiBerto, Christopher M Mazzone, Jonathan Sugam, Daniel W Bloodgood, J Andrew Hardaway, Mariya Husain, Alexis Kendra, Nora M McCall, Alberto J Lopez, Thomas L Kash, Emily G Lowery-Giont. Serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-08-23. PMID:35999277. |
serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray. |
2022-08-23 |
2023-08-14 |
Not clear |
| Laura Durieux, Karine Herbeaux, Christopher Borcuk, Cécile Hildenbrand, Virginie Andry, Yannick Goumon, Alexandra Barbelivien, Chantal Mathis, Demian Bataglia, Monique Majchrzak, Lucas Lecourtie. Functional brain-wide network mapping during acute stress exposure in rats: Interaction between the lateral habenula and cortical, amygdalar, hypothalamic and monoaminergic regions. The European journal of neuroscience. 2022-08-22. PMID:35993349. |
it has been known for decades that the main structures engaged during the stress response are the medial prefrontal cortex, the amygdala, the hippocampus, the hypothalamus, the monoaminergic systems (noradrenaline, dopamine, serotonin), and the periaqueductal gray. |
2022-08-22 |
2023-08-14 |
rat |
| Priscila Vázquez-León, Abraham Miranda-Páez, Kenji Valencia-Flores, Hugo Sánchez-Castill. Defensive and Emotional Behavior Modulation by Serotonin in the Periaqueductal Gray. Cellular and molecular neurobiology. 2022-07-28. PMID:35902460. |
defensive and emotional behavior modulation by serotonin in the periaqueductal gray. |
2022-07-28 |
2023-08-14 |
Not clear |
| Thatiane De Oliveira Sergio, Alana Tercino Frias, Heloisa Helena Vilela-Costa, Danielle Cg De Oliveira, Antônio W Zuardi, Hélio Zangross. Serotonin mediates the panicolytic-like effect of oxytocin in the dorsal periaqueductal gray. Journal of psychopharmacology (Oxford, England). vol 34. issue 4. 2021-06-25. PMID:32108540. |
serotonin mediates the panicolytic-like effect of oxytocin in the dorsal periaqueductal gray. |
2021-06-25 |
2023-08-13 |
Not clear |
| Kenichi Serizawa, Haruna Tomizawa-Shinohara, Hideyuki Yasuno, Kenji Yogo, Yoshihiro Matsumot. Anti-IL-6 Receptor Antibody Inhibits Spontaneous Pain at the Pre-onset of Experimental Autoimmune Encephalomyelitis in Mice. Frontiers in neurology. vol 10. 2020-10-01. PMID:31024434. |
measurement of 5-ht in the spinal cord and functional imaging of the periaqueductal gray (pag) were also performed. |
2020-10-01 |
2023-08-13 |
mouse |
| Renan G Brito, Lynn A Rasmussen, Kathleen A Sluk. Regular physical activity prevents development of chronic muscle pain through modulation of supraspinal opioid and serotonergic mechanisms. Pain reports. vol 2. issue 5. 2020-09-29. PMID:29392233. |
the periaqueductal gray (pag) and rostral ventromedial medulla (rvm) are key nuclei in opioid-induced analgesia, and opioids interact with serotonin to produce analgesia. |
2020-09-29 |
2023-08-13 |
Not clear |
| Srinivasa P Kommajosyula, Carl L Faingol. Neural activity in the periaqueductal gray and other specific subcortical structures is enhanced when a selective serotonin reuptake inhibitor selectively prevents seizure-induced sudden death in the DBA/1 mouse model of sudden unexpected death in epilepsy. Epilepsia. vol 60. issue 6. 2020-04-10. PMID:31056750. |
neural activity in the periaqueductal gray and other specific subcortical structures is enhanced when a selective serotonin reuptake inhibitor selectively prevents seizure-induced sudden death in the dba/1 mouse model of sudden unexpected death in epilepsy. |
2020-04-10 |
2023-08-13 |
mouse |
| R.L. Nogueira, F.G. Graef. 5-HT mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey. Behavioural pharmacology. vol 2. issue 1. 2019-11-20. PMID:11224050. |
5-ht mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey. |
2019-11-20 |
2023-08-12 |
rat |
| R.L. Nogueira, F.G. Graef. 5-HT mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey. Behavioural pharmacology. vol 2. issue 1. 2019-11-20. PMID:11224050. |
a previous study from this laboratory reported an antiaversive effect of the beta-adrenoceptor blocker propranolol microinjected into the dorsal periaqueductal grey (dpag) of the rat, that was antagonized by the 5-ht(2) receptor blocker ritanserin. |
2019-11-20 |
2023-08-12 |
rat |
| Lígia Renata Rodrigues Tavares, Daniela Baptista-de-Souza, Azair Canto-de-Souz. Activation of 5-HT Neuropharmacology. vol 135. 2019-02-20. PMID:29548885. |
systemic and/or intracerebral [e.g., periaqueductal gray matter, amygdala) injections of antiaversive drugs [e.g., serotonin (5-ht) ligands, selective serotonin reuptake inhibitors (ssris)] have been used to change epm-open arm confinement induced antinociception (oaa). |
2019-02-20 |
2023-08-13 |
Not clear |
| Daniela Baptista-de-Souza, Vinícius Pelarin, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souz. Interplay between 5-HT Neuropharmacology. vol 140. 2019-02-20. PMID:30056125. |
as a type of defensive reaction, the oaa has been investigated through systemic and intramesencephalic (e.g., dorsal portion of the periaqueductal gray - dpag) injections of anxiolytic-like drugs [e.g., serotonergic (5-ht) receptor agonists or antagonists]. |
2019-02-20 |
2023-08-13 |
Not clear |
| Takeya Kitta, Takahiko Mitsui, Yukiko Kanno, Hiroki Chiba, Kimihiko Moriya, Mitsuhiro Yoshioka, Nobuo Shinohar. Differences in neurotransmitter systems of ventrolateral periaqueductal gray between the micturition reflex and nociceptive regulation: An in vivo microdialysis study. International journal of urology : official journal of the Japanese Urological Association. vol 23. issue 7. 2018-08-07. PMID:27062256. |
to elucidate the possible involvement of glutamate and serotonin (5-hydroxytryptamine) neurons in the ventrolateral midbrain periaqueductal gray during noxious stimulation. |
2018-08-07 |
2023-08-13 |
Not clear |
| Tabinda Zafar, Charly Brouillard, Laurence Lanfumey, Caroline Sévoz-Couch. A hypothalamo-midbrain-medullary pathway involved in the inhibition of the respiratory chemoreflex response induced by potassium cyanide in rodents. Neuropharmacology. vol 128. 2018-07-13. PMID:28987939. |
dmh activation reduces the cardiac chemoreflex response via the dorsolateral part of the periaqueductal grey matter (dlpag) and serotonin receptors (5-ht |
2018-07-13 |
2023-08-13 |
Not clear |
| Paula Sm Yamashita, Ailton Spiacci, James E Hassel, Christopher A Lowry, Helio Zangross. Disinhibition of the rat prelimbic cortex promotes serotonergic activation of the dorsal raphe nucleus and panicolytic-like behavioral effects. Journal of psychopharmacology (Oxford, England). vol 31. issue 6. 2018-03-22. PMID:28071216. |
our findings suggest that the pl-dr pathway, through dr serotonergic stimulation, is involved in the control of panic-related behaviors by control of serotonin release in structures that modulate panic responses, such as the dorsal periaqueductal gray. |
2018-03-22 |
2023-08-13 |
rat |
| Gislaine Cardoso de Souza Fiaes, Camila Marroni Roncon, Caio Cesar Sestile, Jhonatan Christian Maraschin, Rodolfo Luis Silva Souza, Mauro Porcu, Elisabeth Aparecida Aud. Panicolytic-like effect of tramadol is mediated by opioid receptors in the dorsal periaqueductal grey. Behavioural brain research. vol 326. 2018-03-07. PMID:28245977. |
considering that dorsal periaqueductal grey (dpag) is the main brain structure related to the pathophysiology of panic disorder (pd), this study also evaluated the participation of 5-ht and opioid receptors located in the dpag in the panicolytic-like effect of tramadol. |
2018-03-07 |
2023-08-13 |
rat |