| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isidro Ferre. Historical review: The golden age of the Golgi method in human neuropathology. Journal of neuropathology and experimental neurology. 2024-04-16. PMID:38622902. |
although a relatively small number of laboratories applied these methods, their impact was crucial by increasing knowledge about: (1) the morphology, orientation, and localization of neurons in human cerebral and cerebellar malformations and ganglionic tumors, and (2) the presence of abnormal structures including large and thin spines (spine dysgenesis) in several disorders linked to mental retardation, focal enlargements of the axon hillock and dendrites (meganeurites) in neuronal storage diseases, growth cone-like appendages in alzheimer disease, as well as abnormal structures in other dementias. |
2024-04-16 |
2024-04-18 |
human |
| Christopher L McElroy, Brian Wang, Hongxia Zhang, Kunlin Ji. Cerebellum and Aging: Update and Challenges. Aging and disease. 2024-03-19. PMID:38502583. |
additionally, we explore the the effects of alcoholism on the aging cerebellum as well as the role of the cerebellum in diseases such as alzheimer's, parkinson's, and multiple sclerosis. |
2024-03-19 |
2024-03-23 |
Not clear |
| Jessica A Bernard, Kaitlin M McOwen, Angelina T Huyn. New Frontiers for the Understanding of Aging: The Power and Possibilities of Studying the Cerebellum. Current opinion in behavioral sciences. vol 54. 2024-03-18. PMID:38496767. |
recent frameworks have suggested that the cerebellum may act as scaffolding for cortical function, and there is an emerging literature implicating the structure in alzheimer's disease. |
2024-03-18 |
2024-03-20 |
Not clear |
| Jessica A Bernar. Cerebello-Hippocampal Interactions in the Human Brain: A New Pathway for Insights Into Aging. Cerebellum (London, England). 2024-03-04. PMID:38438826. |
given the role of both regions in cognition and aging, and emerging evidence indicating that the cerebellum is impacted in age-related neurodegenerative disease such as alzheimer's, i propose that further attention to this circuit is warranted. |
2024-03-04 |
2024-03-07 |
human |
| Ivan A Herrejon, T Bryan Jackson, Tracey H Hicks, Jessica A Bernar. Functional Connectivity Differences in Distinct Dentato-Cortical Networks in Alzheimer's Disease and Mild Cognitive Impairment. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352603. |
recent research has implicated the cerebellum in alzheimer's disease (ad), and cerebro-cerebellar network connectivity is emerging as a possible contributor to symptom severity. |
2024-02-14 |
2024-02-16 |
human |
| Lucas Trevizani Rasmussen, Roger Willian de Labio, Mônica Pezenatto Dos Santos, Bruno Mari Fredi, Eduardo Federighi Baisi Chagas, Elizabeth Suchi Chen, Gustavo Turecki, Marília de Arruda Cardoso Smith, Spencer Luiz Marques Payã. Changes in Expression of Key Genes in Alzheimer's Disease: A Specific Brain Tissue Change. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-01-24. PMID:38267766. |
in the present study, the expression of ten genes (app, ps1 and ps2, apoe, apba2, lrp1, grin2b, insr, gjb1, and ide) involved in the main pathways related to alzheimer's disease were analyzed in auditory cortices and cerebellum from 29 ad patients and 29 healthy older adult. |
2024-01-24 |
2024-01-27 |
Not clear |
| Igor Y Iskusnykh, Anastasia A Zakharova, Evgenii D Kryl'skii, Tatyana N Popov. Aging, Neurodegenerative Disorders, and Cerebellum. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256091. |
diminished cerebellar function results in the motor and cognitive impairment observed in patients with neurodegenerative disorders such as alzheimer's disease (ad), vascular dementia (vd), parkinson's disease (pd), huntington's disease (hd), spinal muscular atrophy (sma), amyotrophic lateral sclerosis (als), friedreich's ataxia (frda), and multiple sclerosis (ms), and even during the normal aging process. |
2024-01-23 |
2024-01-25 |
Not clear |
| Gianluca Lopez, Shino D Magaki, Christopher Kazu Williams, Annlia Paganini-Hill, Harry V Vinter. Characterization of cerebellar amyloid-β deposits in Alzheimer disease. Journal of neuropathology and experimental neurology. 2023-12-19. PMID:38114098. |
characterization of cerebellar amyloid-β deposits in alzheimer disease. |
2023-12-19 |
2023-12-23 |
Not clear |
| Gianluca Lopez, Shino D Magaki, Christopher Kazu Williams, Annlia Paganini-Hill, Harry V Vinter. Characterization of cerebellar amyloid-β deposits in Alzheimer disease. Journal of neuropathology and experimental neurology. 2023-12-19. PMID:38114098. |
cerebellar amyloid-β (aβ) plaques are a component of the diagnostic criteria used in thal staging and abc scoring for alzheimer disease (ad) neuropathologic change. |
2023-12-19 |
2023-12-23 |
Not clear |
| Yu Chen, Salvatore Spina, Patrick Callahan, Lea T Grinberg, William W Seeley, Howard J Rosen, Joel H Kramer, Bruce L Miller, Katherine P Ranki. Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-12-18. PMID:38109286. |
associations of cerebellar atrophy with specific neuropathologies in alzheimer's disease and related dementias (adrd) have not been systematically analyzed. |
2023-12-18 |
2023-12-21 |
Not clear |
| Masaki Taka. [Eserine, in Crooked House and Curtain]. Brain and nerve = Shinkei kenkyu no shinpo. vol 75. issue 12. 2023-12-14. PMID:38097226. |
in clinical medicine, eserine was used as an ophthalmic treatment for glaucoma and considered as a treatment for myasthenia gravis, alzheimer's disease, and hereditary cerebellar ataxias. |
2023-12-14 |
2023-12-17 |
Not clear |
| Jessica R Gaunt, Norliyana Zainolabidin, Alaric K K Yip, Jia Min Tan, Aloysius Y T Low, Albert I Chen, Toh Hean Ch'n. Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology. Journal of neuroinflammation. vol 20. issue 1. 2023-11-18. PMID:37978387. |
alzheimer's disease (ad) pathology and amyloid-beta (aβ) plaque deposition progress slowly in the cerebellum compared to other brain regions, while the entorhinal cortex (ec) is one of the most vulnerable regions. |
2023-11-18 |
2023-11-20 |
mouse |
| Maxim L Bychkov, Aizek B Isaev, Alexander A Andreev-Andrievskiy, Konstantin Petrov, Alexander S Paramonov, Mikhail P Kirpichnikov, Ekaterina N Lyukmanov. Aβ1-42 Accumulation Accompanies Changed Expression of Ly6/uPAR Proteins, Dysregulation of the Cholinergic System, and Degeneration of Astrocytes in the Cerebellum of Mouse Model of Early Alzheimer Disease. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834299. |
aβ1-42 accumulation accompanies changed expression of ly6/upar proteins, dysregulation of the cholinergic system, and degeneration of astrocytes in the cerebellum of mouse model of early alzheimer disease. |
2023-10-14 |
2023-10-15 |
mouse |
| Simone D'Angiolini, Maria Sofia Basile, Emanuela Mazzon, Agnese Gugliandol. In Silico Analysis Reveals the Modulation of Ion Transmembrane Transporters in the Cerebellum of Alzheimer's Disease Patients. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762226. |
in silico analysis reveals the modulation of ion transmembrane transporters in the cerebellum of alzheimer's disease patients. |
2023-09-28 |
2023-10-07 |
human |
| Youngyun Jin, Taewan Kim, Taewoon Ki. Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice. Journal of integrative neuroscience. vol 22. issue 5. 2023-09-21. PMID:37735133. |
the cerebellum is an area of the brain that is prone to damage in individuals with alzheimer's disease (ad). |
2023-09-21 |
2023-10-07 |
mouse |
| Wensheng Guo, Xin Mao, Ding Han, Hongqi Wang, Wanning Zhang, Guitao Zhang, Ning Zhang, Binbin Nie, Hui Li, Yizhi Song, Yan Wu, Lirong Chan. Sleep deprivation aggravated amyloid β oligomers-induced damage to the cerebellum of rats: Evidence from magnetic resonance imaging. Aging brain. vol 4. 2023-08-21. PMID:37600754. |
for quite a long time, researches on alzheimer's disease (ad) primarily focused on the cortex and hippocampus, while the cerebellum has been ignored because of its abnormalities considered to appear in the late stage of ad. |
2023-08-21 |
2023-09-07 |
rat |
| Emma F Garland, Oliver Dennett, Laurie C Lau, David S Chatelet, Michel Bottlaender, James A R Nicoll, Delphine Boch. The mitochondrial protein TSPO in Alzheimer's disease: relation to the severity of AD pathology and the neuroinflammatory environment. Journal of neuroinflammation. vol 20. issue 1. 2023-08-14. PMID:37580767. |
in alzheimer's disease (ad), the cerebellum is the pseudo-reference region for comparison with the cerebral cortex due to the absence of ad pathology and lower levels of tspo. |
2023-08-14 |
2023-09-07 |
human |
| Elizabeth R Paitel, Kristy A Nielso. Cerebellar EEG source localization reveals age-related compensatory activity moderated by genetic risk for Alzheimer's disease. Psychophysiology. 2023-07-26. PMID:37493042. |
cerebellar eeg source localization reveals age-related compensatory activity moderated by genetic risk for alzheimer's disease. |
2023-07-26 |
2023-08-14 |
Not clear |
| Cheng Cheng, Cui Yang, Congcong Jia, Qingshan Wan. The Role of Cerebellum in Alzheimer's Disease: A Forgotten Research Corner. Journal of Alzheimer's disease : JAD. 2023-07-17. PMID:37458038. |
the role of cerebellum in alzheimer's disease: a forgotten research corner. |
2023-07-17 |
2023-08-14 |
mouse |
| Cheng Cheng, Cui Yang, Congcong Jia, Qingshan Wan. The Role of Cerebellum in Alzheimer's Disease: A Forgotten Research Corner. Journal of Alzheimer's disease : JAD. 2023-07-17. PMID:37458038. |
in this commentary, we discuss a recently published article in alzheimer's and dementia, which examines changes in cerebellar electrophysiology, sleep-wake cycles, and neuropathology in appswe/ps1Δe9 mice. |
2023-07-17 |
2023-08-14 |
mouse |