| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole A Stoler, Brielle R Crovetti, Ana M Rosas Herrera, Mary Frances Musso, Yi-Chun Carol Li. Rate and management of tympanic membrane perforations in children with Down syndrome and middle ear disorder. International journal of pediatric otorhinolaryngology. vol 180. 2024-05-03. PMID:38701550. |
to characterize the management and outcomes of observation versus surgical intervention of tympanic membrane (tm) perforations in children with down syndrome (ds). |
2024-05-03 |
2024-05-06 |
Not clear |
| Giuseppe Ramacieri, Chiara Locatelli, Michela Semprini, Maria Chiara Pelleri, Maria Caracausi, Allison Piovesan, Michela Cicilloni, Marco Vigna, Lorenza Vitale, Giacomo Sperti, Luigi Tommaso Corvaglia, Gian Luca Pirazzoli, Pierluigi Strippoli, Francesca Catapano, Beatrice Vione, Francesca Antonaro. Zinc metabolism and its role in immunity status in subjects with trisomy 21: chromosomal dosage effect. Frontiers in immunology. vol 15. 2024-05-02. PMID:38694501. |
trisomy 21 (t21), which causes down syndrome (ds), is the most common chromosomal aneuploidy in humankind and includes different clinical comorbidities, among which the alteration of the immune system has a heavy impact on patient's lives. |
2024-05-02 |
2024-05-04 |
human |
| Genki Yamato, Yusuke Tsumura, Hideki Muramatsu, Akira Shimada, Takahiro Imaizumi, Hiroyuki Tsukagoshi, Taeko Kaburagi, Norio Shiba, Yoshiyuki Yamada, Takao Deguchi, Tomoko Kawai, Kiminori Terui, Etsuro Ito, Kenichiro Watanabe, Yasuhide Hayash. Cytokine profiling in 128 patients with transient abnormal myelopoiesis: a report from the JPLSG TAM-10 trial. Blood advances. 2024-05-01. PMID:38691583. |
transient abnormal myelopoiesis (tam) occurs in 10% of neonates with down syndrome (ds). |
2024-05-01 |
2024-05-04 |
Not clear |
| S Hossein Fatemi, Elysabeth D Otte, Timothy D Folsom, Arthur C Eschenlauer, Randall J Roper, Justin W Aman, Paul D Thura. Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations. Genes. vol 15. issue 4. 2024-04-27. PMID:38674386. |
down syndrome (ds) is the most common form of inherited intellectual disability caused by trisomy of chromosome 21, presenting with intellectual impairment, craniofacial abnormalities, cardiac defects, and gastrointestinal disorders. |
2024-04-27 |
2024-04-29 |
mouse |
| Erica Staurenghi, Gabriella Testa, Valerio Leoni, Rebecca Cecci, Lucrezia Floro, Serena Giannelli, Eugenio Barone, Marzia Perluigi, Gabriella Leonarduzzi, Barbara Sottero, Paola Gamb. Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease. Antioxidants (Basel, Switzerland). vol 13. issue 4. 2024-04-27. PMID:38671883. |
down syndrome (ds) is a complex chromosomal disorder considered as a genetically determined form of alzheimer's disease (ad). |
2024-04-27 |
2024-04-29 |
mouse |
| M Matthijs Fockens, Yousif Dawood, Mika J Zwart, Daniël Docter, Jaco Hagoort, Frederik G Dikkers, Bernadette S de Bakke. Micro-CT Imaging of Tracheal Development in Down Syndrome and Non-Down Syndrome Fetuses. The Laryngoscope. 2024-04-27. PMID:38676421. |
down syndrome (ds) is associated with airway abnormalities including a narrowed trachea. |
2024-04-27 |
2024-04-29 |
Not clear |
| Assem Zein, Alaa Zenhom Mahmoud Hassan, Amr Mohamed Soliman, Mohamed Mohamed Azmy Mohame. Outcomes of surgical treatment of patellar instability in children with Down syndrome. Journal of orthopaedic surgery and research. vol 19. issue 1. 2024-04-26. PMID:38664709. |
patellar instability is a relatively frequent musculoskeletal disorder in children with down syndrome (ds). |
2024-04-26 |
2024-04-28 |
Not clear |
| Luca Pecoraro, Melissa Zadra, Francesco Cavallin, Silvana Lauriola, Giorgio Piacentini, Angelo Pietrobell. Lipid Profile, Eating Habit, and Physical Activity in Children with Down Syndrome: A Prospective Study. Diseases (Basel, Switzerland). vol 12. issue 4. 2024-04-26. PMID:38667526. |
children with down syndrome (ds) frequently undergo health challenges, including a higher prevalence of overweight and obesity. |
2024-04-26 |
2024-04-28 |
Not clear |
| Ayse Nurcan Cebeci, Vera Schempp, Katharina Foertsch, Bettina C Gohlke, Michaela Marx, Helmuth-Guenther Dörr, Joachim Woelfl. Graves' disease in children with Down syndrome. Endocrine connections. 2024-04-25. PMID:38657665. |
while subclinical or overt hypothyroidism are common in down syndrome (ds); graves´ disease (gd) is rare (ranges 0.6%-3%). |
2024-04-25 |
2024-04-28 |
Not clear |
| Silvia Molinari, Chiara Fossati, Maria Laura Nicolosi, Santo Di Marco, Martha Caterina Faraguna, Francesca Limido, Laura Ocello, Claudia Pellegrinelli, Martina Lattuada, Alessandra Gazzarri, Alessandra Lazzerotti, Debora Sala, Chiara Vimercati, Giulia Capitoli, Cecilia Daolio, Andrea Biondi, Adriana Balduzzi, Alessandro Catton. Endocrine, auxological and metabolic profile in children and adolescents with Down syndrome: from infancy to the first steps into adult life. Frontiers in endocrinology. vol 15. 2024-04-24. PMID:38654931. |
down syndrome (ds) is the most common chromosomal disorder worldwide. |
2024-04-24 |
2024-04-28 |
Not clear |
| T L Rutter, R P Hastings, C A Murray, N Enoch, S Johnson, C Stinto. Psychological wellbeing in parents of children with Down syndrome: A systematic review and meta-analysis. Clinical psychology review. vol 110. 2024-04-23. PMID:38652972. |
we report a review examining the psychological wellbeing of parents of children with down syndrome (ds) relative to that of parents of typically developing (td) children. |
2024-04-23 |
2024-04-26 |
Not clear |
| D Bridi, N C Valentini, A C Deslandes, F Copett. Focused attention and intrinsic motivation using animations for instruction of fundamental motor skills in children with Down syndrome. Journal of intellectual disability research : JIDR. 2024-04-22. PMID:38644604. |
children with down syndrome (ds) demonstrate poorer performance in locomotor and ball skills than children with typical development. |
2024-04-22 |
2024-04-24 |
Not clear |
| Mateus Rozalem Aranha, Victor Montal, Hilde van den Brink, Jordi Pegueroles, Maria Carmona-Iragui, Laura Videla, Lucia Maure Blesa, Bessy Benejam, Javier Arranz, Sílvia Valldeneu, Isabel Barroeta, Susana Fernández, Laia Ribas, Daniel Alcolea, Sofía González-Ortiz, Núria Bargalló, Geert Jan Biessels, Rafael Blesa, Alberto Lleó, Artur Martins Coutinho, Cláudia Costa Leite, Alexandre Bejanin, Juan Forte. Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-04-22. PMID:38644660. |
caa is frequent in down syndrome (ds) while hypertension is rare, yet no studies have assessed cmi in ds. |
2024-04-22 |
2024-04-24 |
Not clear |
| Kelsey L Thompson, Emily C Clarke, Heather Wasser, Michaela A Schenkelberg, Seema Agrawal, Erik A Willi. Complementary feeding practices of caregivers of infants with Down syndrome as compared to caregivers of typically developing infants. Appetite. 2024-04-18. PMID:38636668. |
caregiver feeding practices during the complementary feeding period (6 months to 2 years) may be particularly important for infants with down syndrome (ds) as they are at higher risk for later health conditions (e.g., obesity, diabetes) that can be influenced by early feeding practices. |
2024-04-18 |
2024-04-21 |
Not clear |
| Anushri R Patil, Snehal Samal, Nikita H Set. A Novel Physiotherapy Approach for Enhancing Mobility in a 53-Year-Old With Down Syndrome: A Case Report. Cureus. vol 16. issue 3. 2024-04-16. PMID:38623113. |
down syndrome (ds) is a genetic condition developing from a supplementary chromosome 21, referred to as trisomy 21. |
2024-04-16 |
2024-04-18 |
Not clear |
| Sonal Sukreet, Michael S Rafii, Robert A Rissma. From understanding to action: Exploring molecular connections of Down syndrome to Alzheimer's disease for targeted therapeutic approach. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 2. 2024-04-16. PMID:38623383. |
down syndrome (ds) is caused by a third copy of chromosome 21. |
2024-04-16 |
2024-04-18 |
Not clear |
| Emily K Schworer, Benjamin L Handen, Melissa Petersen, Sid O'Bryant, Jamie C Peven, Dana L Tudorascu, Laisze Lee, Sharon J Krinsky-McHale, Christy L Hom, Isabel C H Clare, Bradley T Christian, Nicole Schupf, Joseph H Lee, Elizabeth Head, Mark Mapstone, Ira Lott, Beau M Ances, Shahid Zaman, Adam M Brickman, Florence Lai, H Diana Rosas, Sigan L Hartle. Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 2. 2024-04-16. PMID:38623384. |
people with down syndrome (ds) have a 75% to 90% lifetime risk of alzheimer's disease (ad). |
2024-04-16 |
2024-04-18 |
Not clear |
| Bianca M M Streng, Julie Van Coillie, Joanne G Wildenbeest, Rob S Binnendijk, Gaby Smits, Gerco den Hartog, Wenjun Wang, Jan Nouta, Federica Linty, Remco Visser, Manfred Wuhrer, Gestur Vidarsson, Louis J Bon. IgG1 glycosylation highlights premature aging in Down syndrome. Aging cell. 2024-04-15. PMID:38616780. |
down syndrome (ds) is characterized by lowered immune competence and premature aging. |
2024-04-15 |
2024-04-17 |
Not clear |
| Ujjayini Ghosh, Eric Tse, Marie Shi, Hyunjun Yang, Feng Wang, Gregory E Merz, Stanley B Prusiner, Daniel R Southworth, Carlo Condell. Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold. bioRxiv : the preprint server for biology. 2024-04-15. PMID:38617229. |
down syndrome (ds) is a common genetic condition caused by trisomy of chromosome 21. |
2024-04-15 |
2024-04-17 |
Not clear |
| Jonathan M Artal, Lindsey Randall, Sabina Rubeck, Megan Allyse, Marsha Michie, Kirsten A Riggan, Stephanie Meredith, Brian G Skotk. Parents of children with Down syndrome reflect on their postnatal diagnoses, 2003-2022. American journal of medical genetics. Part A. 2024-04-15. PMID:38619097. |
a 2003 survey revealed the scope of mothers' dissatisfaction with their postnatal support following a diagnosis of down syndrome (ds). |
2024-04-15 |
2024-04-17 |
Not clear |