| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jasper E Visser, Odelia Chorin, H A Jinna. Very Early Levodopa May Prevent Self-Injury in Lesch-Nyhan Disease. Pediatric neurology. vol 155. 2024-04-23. PMID:38653184. |
in lesch-nyhan disease (lnd), early dopamine deficiency is thought to contribute to dystonia and self-injury, gradually developing over the first years of life. |
2024-04-23 |
2024-04-26 |
Not clear |
| Ken Momosaki, Jun Kido, Shiro Matsumoto, Atsuo Taniguchi, Tomoyuki Akiyama, Takaaki Sawada, Shiro Ozasa, Kimitoshi Nakamur. The Effect of S-Adenosylmethionine Treatment on Neurobehavioral Phenotypes in Lesch-Nyhan Disease: A Case Report. Case reports in neurology. vol 11. issue 3. 2020-09-30. PMID:31607891. |
a 6-month-old boy with lnd presented with generalized dystonia and self-injury behavior that was alleviated after receiving s-adenosylmethionine (same). |
2020-09-30 |
2023-08-13 |
Not clear |
| Julia Thumfart, Bernhard Weschke, Hannelore Ringe, Natalie Weinhold, Dominik Mülle. Acute renal failure unmasking Lesch-Nyhan disease in a patient with tuberous sclerosis complex. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 20. issue 4. 2016-12-13. PMID:27185581. |
in the following months the patient developed clinically a typical neurological phenotype of lnd and tsc with seizures, severe dystonia and developmental delay. |
2016-12-13 |
2023-08-13 |
Not clear |
| Fabián Piedimonte, Juan Carlos Andreani, Leandro Piedimonte, Federico Micheli, Pablo Graff, Valeria Bacar. Remarkable clinical improvement with bilateral globus pallidus internus deep brain stimulation in a case of Lesch-Nyhan disease: five-year follow-up. Neuromodulation : journal of the International Neuromodulation Society. vol 18. issue 2. 2015-11-20. PMID:25603976. |
lesch-nyhan disease (lnd) is a hereditary disorder characterized by hyperuricemia, self-mutilation, developmental retardation, and movement disorders such as spasticity and dystonia. |
2015-11-20 |
2023-08-13 |
Not clear |
| Fabián Piedimonte, Juan Carlos Andreani, Leandro Piedimonte, Federico Micheli, Pablo Graff, Valeria Bacar. Remarkable clinical improvement with bilateral globus pallidus internus deep brain stimulation in a case of Lesch-Nyhan disease: five-year follow-up. Neuromodulation : journal of the International Neuromodulation Society. vol 18. issue 2. 2015-11-20. PMID:25603976. |
we present our experience treating a lnd patient by bilateral globus pallidus internus (gpi) deep brain stimulation (dbs) with improvement in dystonia symptoms and disappearance of self-injurious behavior. |
2015-11-20 |
2023-08-13 |
Not clear |