| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shinji Matsuda, Wataru Kakegawa, Michisuke Yuzak. PhotonSABER: new tool shedding light on endocytosis and learning mechanisms Communicative & integrative biology. vol 12. issue 1. 2020-10-01. PMID:31143361. |
photonsaber: new tool shedding light on endocytosis and learning mechanisms in the central nervous system, activity-dependent endocytosis of postsynaptic ampa-type glutamate receptors (ampa receptors) is thought to mediate long-term depression (ltd), which is a synaptic plasticity model in various neuronal circuits. |
2020-10-01 |
2023-08-13 |
Not clear |
| Feng Cao, Zikai Zhou, Sammy Cai, Wei Xie, Zhengping Ji. Hippocampal Long-Term Depression in the Presence of Calcium-Permeable AMPA Receptors. Frontiers in synaptic neuroscience. vol 10. 2020-09-30. PMID:30483111. |
hippocampal long-term depression in the presence of calcium-permeable ampa receptors. |
2020-09-30 |
2023-08-13 |
mouse |
| Feng Cao, Zikai Zhou, Sammy Cai, Wei Xie, Zhengping Ji. Hippocampal Long-Term Depression in the Presence of Calcium-Permeable AMPA Receptors. Frontiers in synaptic neuroscience. vol 10. 2020-09-30. PMID:30483111. |
the glua2 subunit of ampa glutamate receptors (ampars) has been shown to be critical for the expression of nmda receptor (nmdar)-dependent long-term depression (ltd). |
2020-09-30 |
2023-08-13 |
mouse |
| Tomoo Hiran. Visualization of Exo- and Endocytosis of AMPA Receptors During Hippocampal Synaptic Plasticity Around Postsynaptic-Like Membrane Formed on Glass Surface. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30519162. |
regulation of exo- and endocytosis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)-type glutamate receptor (ampar) plays a critical role in the expression of synaptic plasticity such as long-term potentiation (ltp) and long-term depression (ltd) at excitatory central synapses. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wolfgang Wagner, Kristina Lippmann, Frank F Heisler, Kira V Gromova, Franco L Lombino, Mona K Roesler, Yvonne Pechmann, Sönke Hornig, Michaela Schweizer, Simona Polo, Jürgen R Schwarz, Jens Eilers, Matthias Kneusse. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell reports. vol 28. issue 1. 2020-08-27. PMID:31269433. |
myosin vi drives clathrin-mediated ampa receptor endocytosis to facilitate cerebellar long-term depression. |
2020-08-27 |
2023-08-13 |
Not clear |
| Wolfgang Wagner, Kristina Lippmann, Frank F Heisler, Kira V Gromova, Franco L Lombino, Mona K Roesler, Yvonne Pechmann, Sönke Hornig, Michaela Schweizer, Simona Polo, Jürgen R Schwarz, Jens Eilers, Matthias Kneusse. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell reports. vol 28. issue 1. 2020-08-27. PMID:31269433. |
together, these data suggest that myosin vi directly promotes clathrin-mediated endocytosis of ampa receptors in purkinje cells to mediate cerebellar long-term depression. |
2020-08-27 |
2023-08-13 |
Not clear |
| Angelika Hausser, Katalin Schlet. Coordination of AMPA receptor trafficking by Rab GTPases. Small GTPases. vol 10. issue 6. 2020-04-24. PMID:28628388. |
this review addresses the role of rab gtpases in ampa receptor trafficking in neurons under basal conditions and during activity-induced synaptic plasticity, especially during long-term potentiation (ltp) and long-term depression (ltd). |
2020-04-24 |
2023-08-13 |
Not clear |
| Enhui Pan, Zirun Zhao, James O McNamar. LTD at mossy fiber synapses onto stratum lucidum interneurons requires TrkB and retrograde endocannabinoid signaling. Journal of neurophysiology. vol 121. issue 2. 2020-02-18. PMID:30517040. |
high-frequency stimulation of the mossy fibers induces long-term depression (ltd) of their calcium-permeable ampa receptor synapses with slins; previous work localized the site of induction to be postsynaptic and the site of expression to be presynaptic. |
2020-02-18 |
2023-08-13 |
mouse |
| Cai-Hong Xiong, Ming-Gang Liu, Lan-Xue Zhao, Mu-Wen Chen, Ling Tang, Ying-Hui Yan, Hong-Zhuan Chen, Yu Qi. M1 muscarinic receptors facilitate hippocampus-dependent cognitive flexibility via modulating GluA2 subunit of AMPA receptors. Neuropharmacology. vol 146. 2020-01-23. PMID:30529302. |
further long-term depression (ltd) in the hippocampal ca1 area induced by m1 machr activation was shown to be dependent on ampa receptor subunit glua2 but not glua1. |
2020-01-23 |
2023-08-13 |
mouse |
| Adam M Van Dyke, T Chase Francis, Haiwen Chen, Aileen M Bailey, Scott M Thompso. Chronic fluoxetine treatment in vivo enhances excitatory synaptic transmission in the hippocampus. Neuropharmacology. vol 150. 2020-01-21. PMID:30851310. |
evidence of potentiation included increases in the ratio of ampa receptor-to nmda receptor-mediated temporoammonic-ca1 synaptic responses, occlusion of electrically evoked long-term potentiation, enhanced long-term depression, impaired anpirtoline-mediated potentiation, and impaired memory recall in the morris water maze task. |
2020-01-21 |
2023-08-13 |
rat |
| Zhi-Xiang Xu, Ji-Wei Tan, Haifei Xu, Cassandra J Hill, Olga Ostrovskaya, Kirill A Martemyanov, Baoji X. Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling. Nature communications. vol 10. issue 1. 2019-12-12. PMID:31399584. |
we found that caspase-2 deficiency led to deficits in dendritic spine pruning, internalization of ampa receptors and long-term depression. |
2019-12-12 |
2023-08-13 |
mouse |
| Wataru Kakegawa, Akira Katoh, Sakae Narumi, Eriko Miura, Junko Motohashi, Akiyo Takahashi, Kazuhisa Kohda, Yugo Fukazawa, Michisuke Yuzaki, Shinji Matsud. Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning. Neuron. vol 99. issue 5. 2019-08-01. PMID:30122381. |
long-term depression (ltd) of ampa-type glutamate receptor (ampa receptor)-mediated synaptic transmission has been proposed as a cellular substrate for learning and memory. |
2019-08-01 |
2023-08-13 |
Not clear |
| Ankit Awasthi, Binu Ramachandran, Saheeb Ahmed, Eva Benito, Yo Shinoda, Noam Nitzan, Alina Heukamp, Sabine Rannio, Henrik Martens, Jonas Barth, Katja Burk, Yu Tian Wang, Andre Fischer, Camin Dea. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science (New York, N.Y.). vol 363. issue 6422. 2019-07-24. PMID:30545844. |
ampa receptor internalization, long-term depression (ltd), and decay of long-term potentiation (ltp) of synaptic strength required calcium-sensing by syt3 and were abolished through syt3 knockout. |
2019-07-24 |
2023-08-13 |
mouse |
| Ruth E Carmichael, Jeremy M Henle. Transcriptional and post-translational regulation of Arc in synaptic plasticity. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:28890422. |
one of the most interesting features of arc-dependent synaptic plasticity is how multiple types of synaptic activity can converge to alter arc transcription and then diverge to induce different plasticity outcomes, ranging from ampa receptor internalisation that promotes long-term depression (ltd), to actin stabilisation that promotes long-term potentiation (ltp). |
2018-12-11 |
2023-08-13 |
Not clear |
| Tetsuya Kimura, Mamiko Suzuki, Takumi Akag. Age-dependent changes in synaptic plasticity enhance tau oligomerization in the mouse hippocampus. Acta neuropathologica communications. vol 5. issue 1. 2018-05-07. PMID:28874186. |
because the phosphorylation process of tau is involved in the trafficking of ampa receptors, which accompanies the long-term depression (ltd) of synapses, we examined the effect of ltd-inducing low-frequency stimulation (lfs) on the formation of pathological tau aggregates in adult and aged wild-type mice. |
2018-05-07 |
2023-08-13 |
mouse |
| M W Lopes, R B Leal, R Guarnieri, M L Schwarzbold, A Hoeller, A P Diaz, G L Boos, K Lin, M N Linhares, J C Nunes, J Quevedo, Z A Bortolotto, H J Markowitsch, S L Lightman, R Wal. A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system. Translational psychiatry. vol 6. issue 12. 2017-12-07. PMID:27959333. |
synapses can be bi-directionally modifiable via potentiation (long-term potentiation, ltp) or depotentiation (long-term depression, ltd) of synaptic transmission efficacy, and the phosphorylation state of ser831 and ser845 sites, in the glua1 subunit of the glutamate ampa receptors, are a critical event for these synaptic neuroplasticity events. |
2017-12-07 |
2023-08-13 |
human |
| Maria Fiuza, Christine M Rostosky, Gabrielle T Parkinson, Alexei M Bygrave, Nagaraj Halemani, Marcio Baptista, Ira Milosevic, Jonathan G Hanle. PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. The Journal of cell biology. vol 216. issue 10. 2017-10-05. PMID:28855251. |
in neurons, the rapid endocytosis of glua2-containing ampa receptors (ampars) in response to nmda receptor (nmdar) stimulation causes a reduction in synaptic strength and is the central mechanism for long-term depression, which underlies certain forms of learning. |
2017-10-05 |
2023-08-13 |
Not clear |
| Zsófia Szíber, Hanna Liliom, Carlos O Oueslati Morales, Attila Ignácz, Anikó Erika Rátkai, Kornelia Ellwanger, Gisela Link, Attila Szűcs, Angelika Hausser, Katalin Schlet. Ras and Rab interactor 1 controls neuronal plasticity by coordinating dendritic filopodial motility and AMPA receptor turnover. Molecular biology of the cell. vol 28. issue 2. 2017-09-21. PMID:27852895. |
consequently loss of rin1 blocks surface ampa receptor down-regulation evoked by chemically induced long-term depression. |
2017-09-21 |
2023-08-13 |
mouse |
| Jacob T Beckley, Patrick K Randall, Rachel J Smith, Benjamin A Hughes, Peter W Kalivas, John J Woodwar. Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene. Addiction biology. vol 21. issue 3. 2017-01-10. PMID:25752326. |
the cb1 receptor antagonist am281 blocked the toluene-induced long-term depression of ampa currents, indicating that this process is dependent on endocannabinoid signaling. |
2017-01-10 |
2023-08-13 |
rat |
| Walter E Babiec, Ryan Guglietta, Thomas J O'Del. Basal levels of AMPA receptor GluA1 subunit phosphorylation at threonine 840 and serine 845 in hippocampal neurons. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 4. 2016-12-13. PMID:26980779. |
dephosphorylation of ampa receptor (ampar) glua1 subunits at two sites, serine 845 (s845) and threonine 840 (t840), is thought to be involved in nmda receptor-dependent forms of long-term depression (ltd). |
2016-12-13 |
2023-08-13 |
Not clear |