| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Changjiu Zhao, Lauren V Riter. The medial preoptic area and its projections to the ventral tegmental area and the periaqueductal gray are activated in response to social play behavior in juvenile rats. Behavioral neuroscience. 2023-03-06. PMID:36877484. |
we hypothesized that the mpoa unites a complementary neural system through which social play induces reward via a projection to the ventral tegmental area (vta) and reduces a negative affective state through a projection to the periaqueductal gray (pag). |
2023-03-06 |
2023-08-14 |
rat |
| Farhana Sakloth, Omar B Sanchez-Reyes, Anne Ruiz, Andrew Nicolais, Randal A Serafini, Kerri D Pryce, Feodora Bertherat, Angélica Torres-Berrío, Ivone Gomes, Lakshmi A Devi, Daniel Wacker, Venetia Zachario. A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward. Molecular pharmacology. vol 103. issue 1. 2022-12-30. PMID:36310031. |
a regional and projection-specific role of rgsz1 in the ventrolateral periaqueductal grey in the modulation of morphine reward. |
2022-12-30 |
2024-04-26 |
Not clear |
| Chi-Wen Wu, Chen Yin Ou, Ying Hao Yu, Yi Chun Yu, Bai Chuang Shyu, Andrew Chih Wei Huan. Involvement of the ventral tegmental area but not periaqueductal gray matter in the paradoxical rewarding and aversive effects of morphine. Behavioral neuroscience. vol 135. issue 6. 2021-12-07. PMID:34323519. |
however, there is no research examining how the ventral tegmental area (vta) or periaqueductal gray matter (pag) regulates morphine's paradoxical effect of reward and aversion. |
2021-12-07 |
2023-08-13 |
Not clear |
| Ciorana Roman-Ortiz, Jessica A Guevara, Roger L Cle. GABAergic basal forebrain projections to the periaqueductal gray promote food consumption, reward and predation. Scientific reports. vol 11. issue 1. 2021-11-26. PMID:34811442. |
gabaergic basal forebrain projections to the periaqueductal gray promote food consumption, reward and predation. |
2021-11-26 |
2023-08-13 |
mouse |
| Mihaela D Iordanova, Joanna Oi-Yue Yau, Michael A McDannald, Laura H Corbi. Neural substrates of appetitive and aversive prediction error. Neuroscience and biobehavioral reviews. vol 123. 2021-06-21. PMID:33453307. |
we explore the neurobiology of both appetitive (reward) and aversive (fear) prediction error with a focus on the mesolimbic dopamine system, the amygdala, ventrolateral periaqueductal gray, hippocampus, cortex and locus coeruleus noradrenaline. |
2021-06-21 |
2023-08-13 |
Not clear |
| Benjamin A Ely, Emily R Stern, Joo-Won Kim, Vilma Gabbay, Junqian X. Detailed mapping of human habenula resting-state functional connectivity. NeuroImage. vol 200. 2020-03-20. PMID:31252057. |
we identified significant positive hb connectivity with: (i) conserved brainstem targets, including the dopaminergic ventral tegmental area, serotonergic raphe nuclei, and periaqueductal gray; (ii) subcortical structures related to reward and motor function, including the nucleus accumbens, dorsal striatum, pallidum, thalamus, and cerebellum; and (iii) cortical areas associated with the salience network and early sensory processing, including the dorsal anterior cingulate, anterior insula, and primary visual and auditory cortices. |
2020-03-20 |
2023-08-13 |
human |
| Dominic Landgraf, Jaimie E Long, David K Wels. Depression-like behaviour in mice is associated with disrupted circadian rhythms in nucleus accumbens and periaqueductal grey. The European journal of neuroscience. vol 43. issue 10. 2017-11-16. PMID:26414405. |
it was found that helplessness is associated with absence of circadian rhythms in the nucleus accumbens and the periaqueductal grey, two of the most critical brain regions within the reward circuit. |
2017-11-16 |
2023-08-13 |
mouse |
| Simone C Motta, Antônio P Carobrez, Newton S Cantera. The periaqueductal gray and primal emotional processing critical to influence complex defensive responses, fear learning and reward seeking. Neuroscience and biobehavioral reviews. vol 76. issue Pt A. 2017-10-30. PMID:28434586. |
the periaqueductal gray and primal emotional processing critical to influence complex defensive responses, fear learning and reward seeking. |
2017-10-30 |
2023-08-13 |
Not clear |
| Kedi Xu, Jiacheng Zhang, Songchao Guo, Xiaoxiang Zhen. Optogenetic Modulation of Locomotor Activity on Free-Behaving Rats. Methods in molecular biology (Clifton, N.J.). vol 1408. 2016-12-13. PMID:26965124. |
the target sites of the rat brain were dorsal periaqueductal gray (dpag) and ventral tegmental area (vta) for the modulation of defensive and reward behaviors, respectively. |
2016-12-13 |
2023-08-13 |
rat |
| Rongjun Yu, Dean Mobbs, Ben Seymour, James B Rowe, Andrew J Calde. The neural signature of escalating frustration in humans. Cortex; a journal devoted to the study of the nervous system and behavior. vol 54. 2014-12-15. PMID:24699035. |
in experiment 2, we used functional magnetic resonance imaging (fmri) to show that both proximity and expended effort modulated brain responses to blocked reward in regions implicated in animal models of reactive aggression, including the amygdala, midbrain periaqueductal grey (pag), insula and prefrontal cortex. |
2014-12-15 |
2023-08-13 |
human |
| Markus Wöhr, Rainer K W Schwartin. Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation. Cell and tissue research. vol 354. issue 1. 2014-11-24. PMID:23576070. |
freezing behavior in response to 22-khz usv is paralleled by increased neuronal activity in brain areas regulating fear and anxiety, such as the amygdala and periaqueductal gray, whereas social approach behavior elicited by 50-khz usv is accompanied by reduced activity levels in the amygdala but enhanced activity in the nucleus accumbens, a brain area implicated in reward processing. |
2014-11-24 |
2023-08-12 |
mouse |
| Alexandru D P Papoiu, Leigh A Nattkemper, Kristen M Sanders, Robert A Kraft, Yiong-Huak Chan, Robert C Coghill, Gil Yosipovitc. Brain's reward circuits mediate itch relief. a functional MRI study of active scratching. PloS one. vol 8. issue 12. 2014-07-31. PMID:24324781. |
a significant involvement of the reward system including the ventral tegmentum of the midbrain, coupled with a mechanism deactivating the periaqueductal gray matter (pag), suggests that itch modulation operates in reverse to the mechanism known to suppress pain. |
2014-07-31 |
2023-08-12 |
human |
| Lauren V Riters, Jesse M S Ellis, Caroline S Angyal, Vincent J Borkowski, Melissa A Cordes, Sharon A Stevenso. Links between breeding readiness, opioid immunolabeling, and the affective state induced by hearing male courtship song in female European starlings (Sturnus vulgaris). Behavioural brain research. vol 247. 2013-10-21. PMID:23473880. |
immunolabeling for met-enkephalin (an opioid neuropeptide involved in reward) in the medial preoptic nucleus, ventromedial nucleus of the hypothalamus, nucleus accumbens, and periaqueductal gray was higher in females with compared to those without nest boxes. |
2013-10-21 |
2023-08-12 |
Not clear |
| Chia Li, Nora M McCall, Alberto J Lopez, Thomas L Kas. Alcohol effects on synaptic transmission in periaqueductal gray dopamine neurons. Alcohol (Fayetteville, N.Y.). vol 47. issue 4. 2013-10-21. PMID:23597415. |
da neurons within the ventral periaqueductal gray (vpag) have been shown to regulate reward but little is known about the functional properties of these neurons, or how they are modified by drugs of abuse. |
2013-10-21 |
2023-08-12 |
mouse |
| Sandra Regina Mota-Ortiz, Marcia Harumi Sukikara, Jackson Cioni Bittencourt, Marcus Vinícius Baldo, Carol Fuzeti Elias, Luciano Freitas Felicio, Newton Sabino Cantera. The periaqueductal gray as a critical site to mediate reward seeking during predatory hunting. Behavioural brain research. vol 226. issue 1. 2012-02-09. PMID:21903137. |
the periaqueductal gray as a critical site to mediate reward seeking during predatory hunting. |
2012-02-09 |
2023-08-12 |
rat |
| G Elliso. Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula. Brain research. Brain research reviews. vol 19. issue 2. 1994-09-22. PMID:7914793. |
it represents one of the major inputs in brain to the raphe nuclei and has anatomical and functional connections to modulate important functions such as sensory gating through thalamus, pain gating through central gray and raphe and motor stereotypies and reward mechanisms through substantia nigra and the ventral tegmental area. |
1994-09-22 |
2023-08-12 |
Not clear |
| R A Wis. Opiate reward: sites and substrates. Neuroscience and biobehavioral reviews. vol 13. issue 2-3. 1989-12-12. PMID:2573023. |
suggestions that the lateral hypothalamus or periaqueductal gray contain opioid reward sites remain to be confirmed. |
1989-12-12 |
2023-08-11 |
Not clear |
| E Miliaressis, J Malett. Summation and saturation properties in the rewarding effect of brain stimulation. Physiology & behavior. vol 41. issue 6. 1988-04-18. PMID:3441529. |
reward saturation occurred with a considerably higher frequency in the central grey than in the hypothalamus. |
1988-04-18 |
2023-08-11 |
human |
| R Thompson, P W Huestis, J Y. Motor learning: nonspecific subcortical mechanisms in rats. Archives of physical medicine and rehabilitation. vol 68. issue 7. 1987-08-13. PMID:3606364. |
adult rats with bilateral lesions in the globus pallidus, substantia nigra, median raphe, midbrain central gray, or pontine reticular formation were tested for novel motor skill learning (sliding a barrel bolt to the right in order to open a door leading to a reward). |
1987-08-13 |
2023-08-11 |
human |
| J E Kelsey, J D Belluzzi, L Stei. Does naloxone suppress self-stimulation by decreasing reward or by increasing aversion? Brain research. vol 307. issue 1-2. 1984-10-19. PMID:6467008. |
fifty-eight rats were implanted with electrodes in the ventrolateral midbrain central gray from which both self-stimulation reward and/or stimulation-produced analgesia can be obtained. |
1984-10-19 |
2023-08-12 |
rat |