All Relations between temporal order and fibroblast growth factor receptor 1
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Anna M Jermakowicz, Alison M Kurimchak, Katherine J Johnson, Florence Bourgain-Guglielmetti, Simon Kaeppeli, Maurizio Affer, Hari Pradhyumnan, Robert K Suter, Winston Walters, Maria Cepero, James S Duncan, Nagi G Aya. RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma. Scientific reports. vol 14. issue 1. 2024-04-23. PMID:38654040. |
to identify the temporal order of resistance mechanisms in gbm we performed quantitative proteomics using multiplex-inhibitor bead mass spectrometry and demonstrated that intrinsic resistance to bet inhibitors in gbm treatment occurs rapidly within hours and involves the fibroblast growth factor receptor 1 (fgfr1) protein. |
2024-04-23 |
2024-04-26 |
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