All Relations between ace2 and fgf7

Publication Sentence Publish Date Extraction Date Species
Hao Meng, Zhiying Liao, Yanting Ji, Dong Wang, Yang Han, Chaolin Huang, Xujuan Hu, Jingyi Chen, Hengrui Zhang, Zonghong Li, Changliang Wang, Hui Sun, Jiaqi Sun, Lihua Chen, Jiaxiang Yin, Jincun Zhao, Tao Xu, Huisheng Li. FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection. Signal transduction and targeted therapy. vol 9. issue 1. 2024-04-24. PMID:38654010. in the current study, we utilized islet organoids derived from human embryonic stem cells (hescs), animal models and covid-19 patients to discover that fibroblast growth factor 7 (fgf7) enhances ace2 expression within the islets, facilitating sars-cov-2 infection and resulting in impaired insulin secretion. 2024-04-24 2024-04-26 human