| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gustaf Tanghöj, Estelle Naumbur. Risk factors for isolated atrial septal defect secundum morbidity. Scientific reports. vol 14. issue 1. 2024-02-27. PMID:38413680. |
down syndrome was the only independent risk factors for associated with cardiac morbidity in children with asd ii (or = 2.25 (95%ci 1.25-4.07). |
2024-02-27 |
2024-03-01 |
Not clear |
| Joanne Given, Joan K Morris, Ester Garne, Elisa Ballardini, Laia Barrachina-Bonet, Clara Cavero-Carbonell, Mika Gissler, Francesca Gorini, Anna Heino, Sue Jordan, Amanda J Neville, Anna Pierini, Ieuan Scanlon, Joachim Tan, Stine K Urhoj, Maria Loan. Prescriptions for insulin and insulin analogues in children with and without major congenital anomalies: a data linkage cohort study across six European regions. European journal of pediatrics. 2023-03-03. PMID:36869270. |
however, children with chromosomal anomalies (rr 2.37, 95% ci 1.91-2.96), and specifically children with down syndrome (rr 3.44, 95% cis 2.70-4.37), down syndrome with congenital heart defects (rr 3.86, 95% cis 2.88-5.16) and down syndrome without congenital heart defects (rr 2.78, 95% cis 1.82-4.27), had a significantly increased risk of > 1 prescription for insulin/insulin analogues aged 0-9 years compared to reference children. |
2023-03-03 |
2023-08-14 |
Not clear |
| Asija Rota Čeprnja, Shelly Melissa Pranić, Martina Šunj, Tonći Kozina, Joško Božić, Slavica Kozin. Impact of Neonatal Body (Dis)Proportionality Determined by the Cephalization Index (CI) on Gross Motor Development in Children with Down Syndrome: A Prospective Cohort Study. Children (Basel, Switzerland). vol 10. issue 1. 2023-01-21. PMID:36670564. |
impact of neonatal body (dis)proportionality determined by the cephalization index (ci) on gross motor development in children with down syndrome: a prospective cohort study. |
2023-01-21 |
2023-08-14 |
Not clear |
| Char Leung, Li Su, Ana Cristina Simões-E-Silva, Luisamanda Selle Arocha, Karina Mary de Paiva, Patricia Haa. Risk for Severe Illness and Death among Pediatric Patients with Down Syndrome Hospitalized for COVID-19, Brazil. Emerging infectious diseases. vol 29. issue 1. 2022-12-27. PMID:36573520. |
after adjustments for sociodemographic and medical factors, patients with down syndrome had 1.8 times higher odds of dying from covid-19 (odds ratio 1.82, 95% ci 1.22-2.68) and 27% longer recovery times (hazard ratio 0.73, 95% ci 0.61-0.86) than patients without down syndrome. |
2022-12-27 |
2023-08-14 |
human |
| Georgina Edwards, Chris Jones, Effie Pearson, Rachel Royston, Chris Oliver, Joanne Tarver, Hayley Crawford, Lauren Shelley, Jane Wait. Prevalence of anxiety symptomatology and diagnosis in syndromic intellectual disability: a systematic review and meta-analysis. Neuroscience and biobehavioral reviews. 2022-06-06. PMID:35661754. |
anxiety prevalence ranged from 9% (95% ci: 4-14) in down syndrome to 73% in rett syndrome (95% ci: 70-77). |
2022-06-06 |
2023-08-14 |
Not clear |
| Haruo Fujino, Minori Ita. Disinfection behavior for COVID-19 in individuals with Down syndrome and caregivers' distress in Japan: a cross-sectional retrospective study. Journal of developmental and physical disabilities. 2022-05-31. PMID:35637873. |
logistic regression showed that caregivers' stress was associated with the irritability of individuals with the disorder (adjusted odds ratio [or] = 8.44, 95% confidence interval [ci] 1.69-42.09) and the burden of infection-prevention behaviors for people with down syndrome (adjusted or = 4.26, 95% ci 1.88-9.65). |
2022-05-31 |
2023-08-13 |
Not clear |
| Luzivan Costa Reis, Wesley Luciano Kaizer, Juliano André Boquet. Geographic distribution of live births and infant mortality from congenital anomalies in Brazil, 2012-2017. Journal of community genetics. vol 12. issue 3. 2021-10-20. PMID:33496933. |
the five ca with the highest rates were polydactyly (9.66/10,000, 95% ci 6.10-9.82), down syndrome (3.40/10,000, 95% ci 3.41-5.99), microcephaly (2.92/10,000, 95% ci 2.91-3.12), hydrocephalus (2.72/10,000, 95% ci 2.65-2.90), and spina bifida (2.44/10,000, 95% ci 2.43-2.64). |
2021-10-20 |
2023-08-13 |
Not clear |
| Aireen Wingert, Jennifer Pillay, Dorothy L Moore, Samantha Guitard, Ben Vandermeer, Michele P Dyson, Angela Sinilaite, Matthew Tunis, Lisa Hartlin. Burden of illness in infants and young children hospitalized for respiratory syncytial virus: A rapid review. Canada communicable disease report = Releve des maladies transmissibles au Canada. vol 47. issue 9. 2021-10-16. PMID:34650335. |
children with versus without down syndrome may have increased hospital length of stay (n=7,206 children; mean difference 3.00 days, 95% ci 1.95-4.05; low certainty). |
2021-10-16 |
2023-08-13 |
Not clear |
| Iêda Maria Orioli, Helen Dolk, Jorge Lopez-Camelo, Boris Groisman, Adriana Benavides-Lara, Lucas Gabriel Gimenez, Daniel Mattos Correa, Marta Ascurra, Eliana de Aquino Bonilha, Maria Aurora Canessa-Tapia, Giovanny Vinícius Araújo de França, Paula Hurtado-Villa, Marisol Ibarra-Ramírez, Rosa Pardo, Dania Maria Pastora, Ignacio Zarante, Flávia Schneider Soares, Flávia Martinez de Carvalho, Mariana Piol. The Latin American network for congenital malformation surveillance: ReLAMC. American journal of medical genetics. Part C, Seminars in medical genetics. vol 184. issue 4. 2021-09-17. PMID:33319501. |
the microcephaly rate was 2.45 per 10,000 births (95% ci 2.35-2.55), hydrocephaly 3.03 (2.92-3.14), spina bifida 2.89 (2.78-3.00), congenital heart defects 15.53 (15.27-15.79), cleft lip 2.02 (1.93-2.11), cleft palate and lip 2.77 (2.66-2.88), talipes 2.56 (2.46-2.67), conjoined twins 0.16 (0.14-0.19), and down syndrome 5.33 (5.18-5.48). |
2021-09-17 |
2023-08-13 |
Not clear |
| Camila Ive Ferreira Oliveira-Brancati, Valéria Cristina Carvalho Ferrarese, Antonio Richieri Costa, Agnes Cristina Fett-Cont. Birth defects in Brazil: Outcomes of a population-based study. Genetics and molecular biology. vol 43. issue 1. 2020-09-28. PMID:31429860. |
the most common congenital anomalies were heart diseases in isolation (11.2%; 95%ci: 7.3-16.9%) followed by down syndrome (9.5%; 95%ci: 5.9-14.8%), neural tube defects (8.9%; 95%ci: 5.4-14.1), urinary tract anomalies (7.7%; 95%ci: 4.4-12.7%), and polydactyly (7.0%; 95%ci: 4.0-12.0%). |
2020-09-28 |
2023-08-13 |
Not clear |
| Mariann Gjervik Heldahl, Beth Eksveen, Marie Bunn. Cochlear implants in eight children with Down Syndrome - Auditory performance and challenges in assessment. International journal of pediatric otorhinolaryngology. vol 126. 2020-02-06. PMID:31442869. |
a small proportion of children with down syndrome (ds) have severe to profound hearing loss and may potentially benefit from a cochlear implant (ci). |
2020-02-06 |
2023-08-13 |
Not clear |
| A. Marc Harrison, Amy C. Cox, Steve Davis, Marion Piedmonte, Jonathan J. Drummond-Webb, Roger B. B. Me. Failed extubation after cardiac surgery in young children: Prevalence, pathogenesis, and risk factors. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. vol 3. issue 2. 2019-11-20. PMID:12780985. |
risk factors for fe included pulmonary hypertension (eor, 38.7; 95% ci, 2.9-25.8; p <.001), down syndrome (eor, 4.6; 95% ci, 1.8-11.8; p =.002), and deep hypothermic circulatory arrest (eor, 4.5; 95% ci, 1.3-17.5; p =.018). |
2019-11-20 |
2023-08-12 |
human |
| Josje D Schoufour, Alyt Oppewal, Hanne J K van der Maarl, Heidi Hermans, Heleen M Evenhuis, Thessa I M Hilgenkamp, Dederieke A Feste. Multimorbidity and Polypharmacy Are Independently Associated With Mortality in Older People With Intellectual Disabilities: A 5-Year Follow-Up From the HA-ID Study. American journal on intellectual and developmental disabilities. vol 123. issue 1. 2019-10-18. PMID:29281324. |
we observed that people classified as having multimorbidity or polypharmacy at baseline were 2.60 (95% ci = 1.86-3.66) and 2.32 (95% ci = 1.70-3.16) times more likely to decease during the follow-up period, respectively, independent of age, sex, level of id, and the presence of down syndrome. |
2019-10-18 |
2023-08-13 |
Not clear |
| Yuan Zhang, Xia He, Xuan Xiong, Junlan Chuan, Lei Zhong, Guo Chen, Dongke Y. The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes. Prenatal diagnosis. vol 39. issue 1. 2019-05-20. PMID:30474229. |
mthfr c677t, but not a1298c, was associated with neural tube defects (or, 1.24; 95% ci, 1.08-1.42) and down syndrome (or, 1.65; 95% ci, 1.39-1.95). |
2019-05-20 |
2023-08-13 |
Not clear |
| Rachel T Sullivan, Peter C Frommelt, Garick D Hil. Earlier Pulmonary Valve Replacement in Down Syndrome Patients Following Tetralogy of Fallot Repair. Pediatric cardiology. vol 38. issue 6. 2017-09-14. PMID:28616649. |
in multivariable analysis, down syndrome (hr 2.3, 95% ci 1.2-4.5, p = 0.02) and transannular patch repair (hr 5.5, 95% ci 1.7-17.6, p = 0.004) were significant risk factors for valve replacement. |
2017-09-14 |
2023-08-13 |
Not clear |
| E Phelan, R Pal, L Henderson, K M J Green, I A Bruc. The management of children with Down syndrome and profound hearing loss. Cochlear implants international. vol 17. issue 1. 2016-09-12. PMID:26252564. |
although, the association between down syndrome (ds) and conductive hearing loss is well recognized, the fact that a small proportion of these children may have a severe to profound sensorineural hearing loss that could benefit from cochlear implantation (ci) is less well understood. |
2016-09-12 |
2023-08-13 |
Not clear |
| Nadia Barahmani, M Tevfik Dorak, Michele R Forman, Michael R Sprehe, Michael E Scheurer, Melissa L Bondy, M Fatih Okcu, Philip J Lup. Evaluating the Role of Birth Weight and Gestational Age on Acute Lymphoblastic Leukemia Risk Among Those of Hispanic Ethnicity. Pediatric hematology and oncology. vol 32. issue 6. 2016-07-11. PMID:26237584. |
the risk of developing all was higher among hispanics who were lga (odds ratio [or] = 1.90, 95% confidence interval [ci]: 1.34-2.68) compared with lga non-hispanic whites (or = 1.27, 95% ci: 0.87-1.86) after adjusting for infant gender, year of birth, maternal age, birth order, and presence of down syndrome. |
2016-07-11 |
2023-08-13 |
Not clear |
| Francesca Galluzzi, Lorenzo Pignataro, Renato Maria Gaini, Werner Garavell. Drug induced sleep endoscopy in the decision-making process of children with obstructive sleep apnea. Sleep medicine. vol 16. issue 3. 2015-12-18. PMID:25754384. |
in children with down syndrome, the combined estimated rate of hypertrophic tonsils and/or adenoids was 62% (95%ci: 44-79%). |
2015-12-18 |
2023-08-13 |
Not clear |
| Joan K Morris, Ester Garne, Diana Wellesley, Marie-Claude Addor, Larraitz Arriola, Ingeborg Barisic, Judit Beres, Fabrizio Bianchi, Judith Budd, Carlos Matias Dias, Miriam Gatt, Kari Klungsoyr, Babak Khoshnood, Anna Latos-Bielenska, Carmel Mullaney, Vera Nelen, Amanda J Neville, Mary O'Mahony, Annette Queisser-Luft, Hanitra Randrianaivo, Judith Rankin, Anke Rissmann, Cath Rounding, Antonin Sipek, Sylvia Stoianova, David Tucker, Hermien de Walle, Lyubov Yevtushok, Maria Loane, Helen Dol. Major congenital anomalies in babies born with Down syndrome: a EUROCAT population-based registry study. American journal of medical genetics. Part A. vol 164A. issue 12. 2015-07-10. PMID:25257471. |
overall, 43.6% (95% ci: 42.4-44.7%) of births with down syndrome had a cardiac anomaly and 15.0% (14.2-15.8%) had a non-cardiac anomaly. |
2015-07-10 |
2023-08-13 |
Not clear |
| David O'Connor, Jessica Bate, Rachel Wade, Rachel Clack, Sunita Dhir, Rachael Hough, Ajay Vora, Nick Goulden, Sujith Samarasingh. Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003. Blood. vol 124. issue 7. 2015-04-27. PMID:24904116. |
down syndrome was the most significant risk factor for irm (odds ratio [or], 12.08; 95% ci, 6.54-22.32; p < .0001). |
2015-04-27 |
2023-08-13 |
Not clear |