| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T L Rutter, R P Hastings, C A Murray, N Enoch, S Johnson, C Stinto. Psychological wellbeing in parents of children with Down syndrome: A systematic review and meta-analysis. Clinical psychology review. vol 110. 2024-04-23. PMID:38652972. |
relative to their counterparts with td children, mothers and fathers of children with ds reported higher levels of parenting stress (mothers: g = 0.57, 95% ci [0.33, 0.81]; fathers: g = 0.40, [0.24, 0.56]), depressive symptoms (mothers: g = 0.42, [0.23, 0.61]; fathers: g = 0.25, [0.02, 0.48]) and psychological distress (mothers: g = 0.45, [0.30, 0.60]; fathers: g = 0.63, [0.26, 0.99]). |
2024-04-23 |
2024-04-26 |
Not clear |
| Changhun Kim, Jaeseong Jeong, Jinhee Cho. Effects of Class Imbalance and Data Scarcity on the Performance of Binary Classification Machine Learning Models Developed Based on ToxCast/Tox21 Assay Data. Chemical research in toxicology. vol 35. issue 12. 2022-12-19. PMID:36475638. |
an assay matrix based on ci and ds was prepared for 335 assays with biologically intended target information, and 28 ci assays and 3 ds assays were selected. |
2022-12-19 |
2023-08-14 |
Not clear |
| Katerina Kaikoushi, Maria Karanikola, Nicos Middleton, Andreas Chatzittofis, Maria Nystazaki, Evanthia Bella, Constantinos Stylianou, Evgenios Kinnis, Skevi Veniamin, Maria Pitta, George Alevizopoulo. Depressive symptoms in involuntary hospitalized patients in Cyprus: Socio-demographic and psychopathological characteristics. Psychiatrike = Psychiatriki. 2021-08-14. PMID:34390553. |
in multivariable logistic regression analysis only female sex [or (95%ci) = 3.28 (1.33.-8.04), p=0.01)] and a mood disorder diagnosis [or95% ci: 15.22(4.13.-56.14), p<0.0001)] retained a statistically significant association with ds. |
2021-08-14 |
2023-08-13 |
human |
| Kensuke Komatsu, Sota Kimura, Yoko Kiryu, Shinichi Oka, Hidehiko Takahashi, Eisuke Matsushima, Takashi Takeuch. Detailed analysis of social support and proactive coping with depressive symptoms in Japanese HIV-infected individuals. AIDS care. 2021-06-14. PMID:34082633. |
with regard to coping, higher levels of instrumental support seeking (aor 1.09, 95%ci 1.01-1.18), lower levels of proactive coping (aor 0.91, 95%ci 0.87-0.96) and lower levels of emotional support seeking (aor 0.82, 95%ci 0.72-0.92) were significantly associated with ds. |
2021-06-14 |
2023-08-13 |
human |
| Mariann Gjervik Heldahl, Beth Eksveen, Marie Bunn. Cochlear implants in eight children with Down Syndrome - Auditory performance and challenges in assessment. International journal of pediatric otorhinolaryngology. vol 126. 2020-02-06. PMID:31442869. |
a small proportion of children with down syndrome (ds) have severe to profound hearing loss and may potentially benefit from a cochlear implant (ci). |
2020-02-06 |
2023-08-13 |
Not clear |
| Aleksandra M Pavlovic, Tatjana Pekmezovic, Jasna Zidverc Trajkovic, Gordana Tomic, Edita Cvitan, Nada Sterni. Increased risk of cognitive impairment and more severe brain lesions in hypertensive compared to non-hypertensive patients with cerebral small vessel disease. Journal of clinical hypertension (Greenwich, Conn.). vol 20. issue 9. 2019-12-06. PMID:30058256. |
in univariate analysis, ht was associated with vascular cognitive impairment (vci) (or 2.30, 1.53-3.45, p < 0.0001), functional status (or 1.47, 1.11-1.95, p = 0.007), depression (or 2.13, 1.23-3.70, p = 0.007), tarwmc (or 1.10, 1.05-1.16 95% ci, p < 0.0001), fazekas pv score (or 1.34, 1.08-1.67 95% ci, p = 0.008), fazekas ds score (or 1.95, 1.44-2.63 95% ci, p < 0.0001) and total number of lacunes (or 1.10, 1.02-1.18 95% ci, p = 0.009). |
2019-12-06 |
2023-08-13 |
Not clear |
| Claudia Sinoo, Iris Marie-Louise de Lange, Paul Westers, Willem Boudewijn Gunning, Marian Jacqueline Jongmans, Eva Henriëtte Brilstr. Behavior problems and health-related quality of life in Dravet syndrome. Epilepsy & behavior : E&B. vol 90. 2019-07-09. PMID:30578097. |
the current study aimed to give more insight into (1) the prevalence of a wide range of specific behavior difficulties and aspects of health-related quality of life (hrqol) in patients with ds compared with the general population (gp) and patients with epilepsy without ds, (2) the relations between these behavior problems and different aspects of hrqol, and (3) the associations between seizure frequency, cognitive impairment (ci), behavior problems, and hrqol, based on a conceptual model. |
2019-07-09 |
2023-08-13 |
Not clear |
| E Phelan, R Pal, L Henderson, K M J Green, I A Bruc. The management of children with Down syndrome and profound hearing loss. Cochlear implants international. vol 17. issue 1. 2016-09-12. PMID:26252564. |
although, the association between down syndrome (ds) and conductive hearing loss is well recognized, the fact that a small proportion of these children may have a severe to profound sensorineural hearing loss that could benefit from cochlear implantation (ci) is less well understood. |
2016-09-12 |
2023-08-13 |
Not clear |
| Minoru Gotoh, Kimihiro Okubo, Kazuhiro Hashiguchi, Ken-ichiro Wakabayashi, Sho Kanzaki, Nobuaki Tanaka, Masato Fujioka, Kayoko Kawashima, Kiyochika Suematsu, Koichi Sasaki, Manabu Iwasaki, Hajime Yamamotoy. Noninvasive biological evaluation of response to pranlukast treatment in pediatric patients with Japanese cedar pollinosis. Allergy and asthma proceedings. vol 33. issue 6. 2013-06-18. PMID:23394502. |
the difference in the least square means for nasal obstruction between the plk ds and placebo was -0.25 (95% ci, -0.36 to -0.14) with a value of p < 0.0001. |
2013-06-18 |
2023-08-12 |
Not clear |
| Ken-ichiro Wakabayashi, Kazuhiro Hashiguchi, Sho Kanzaki, Masato Fujioka, Nobuaki Tanaka, Kayoko Kawashima, Kiyochika Suematsu, Hajime Yamamotoya, Manabu Iwasaki, Minoru Gotoh, Seiji Horibe, Kensei Naito, Kimihiro Okub. Pranlukast dry syrup inhibits symptoms of Japanese cedar pollinosis in children using OHIO Chamber. Allergy and asthma proceedings. vol 33. issue 1. 2012-07-16. PMID:22370535. |
the difference in the least square means in tnss between the plk ds-treated group and placebo group was -0.37 (95% ci, -0.54, -0.20) with a value of p < 0.0001, showing that plk ds significantly suppressed the nasal symptoms. |
2012-07-16 |
2023-08-12 |
human |
| A M W Coppus, H M Evenhuis, G-J Verberne, F E Visser, A Arias-Vasquez, F A Sayed-Tabatabaei, J Vergeer-Drop, P Eikelenboom, W A van Gool, C M van Duij. The impact of apolipoprotein E on dementia in persons with Down's syndrome. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17250929. |
when pooling our data in a meta-analysis, the apoe epsilon4 allele shows a 1.59-fold (95%ci: 1.19-2.12) increase in risk of dementia in persons with ds. |
2008-06-20 |
2023-08-12 |
Not clear |
| H Kasuda, S Akazawa, R Shimiz. The echocardiographic assessment of left ventricular performance during sevoflurane and halothane anesthesia. Journal of anesthesia. vol 4. issue 4. 2005-02-07. PMID:15235959. |
the changes in left ventricular diastolic and systolic dimension (dd and ds), fractional shortening (fs), mean velocity of circumferential fiber shortening (mvcf), left ventricular diastolic and systolic volume (vd and vs), stroke volume (sv), ejection fraction (ef) and cardiac index (ci) were evaluated by echocardiography. |
2005-02-07 |
2023-08-12 |
Not clear |
| Q Li, R R H. Hemodynamic effects of agmatine in Dahl salt-sensitive hypertensive and Dahl salt-resistant rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 53. issue 5. 2002-11-07. PMID:11833418. |
taken together, the results indicate that agmatine can dose-dependently decrease hr, map, lvp, +/- lv dp/dtmax, ci and tpri in ds hypertensive and dr normotensive rats. |
2002-11-07 |
2023-08-12 |
rat |
| Q Li, R R H. Hemodynamic effects of agmatine in Dahl salt-sensitive hypertensive and Dahl salt-resistant rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 53. issue 5. 2002-11-07. PMID:11833418. |
decreased heart rate (hr), mean arterial pressure (map), left ventricular blood pressure (lvp), the first derivative of lvp (lv dp/dt), cardiac index (ci) and total peripheral resistance index (tpri) in a dose-dependent manner in both ds and dr rats, and the decreases in map, lvp, +/- lv dp/dtmax and tpri at the same dose of agmatine in dr rats were less than those in ds hypertensive rats. |
2002-11-07 |
2023-08-12 |
rat |
| N Schupf, W Zigman, D Kapell, J H Lee, J Kline, B Levi. Early menopause in women with Down's syndrome. Journal of intellectual disability research : JIDR. vol 41 ( Pt 3). 1997-09-03. PMID:9219076. |
the age-adjusted likelihood of menopause was twice as high in women with ds syndrome as in women with other intellectual disability (or = 2.3; 95% ci = 1.1-4.9). |
1997-09-03 |
2023-08-12 |
Not clear |
| N Schupf, D Kapell, J H Lee, R Ottman, R Mayeu. Increased risk of Alzheimer's disease in mothers of adults with Down's syndrome. Lancet (London, England). vol 344. issue 8919. 1994-09-02. PMID:7914304. |
there was an increase in risk of dementia among mothers of ds probands compared with control mothers (risk ratio 2.6 [95% ci 0.9-7.3]). |
1994-09-02 |
2023-08-12 |
Not clear |
| E L Rodríguez Echandía, S T Broitman, M R Fóscol. Effect of the chronic ingestion of chlorimipramine and desipramine on the hole board response to acute stresses in male rats. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:3575344. |
inasmuch as ci and ds have different relative potency at noradrenergic and serotonergic systems, it is speculated that this might be in part responsible for their differences as stress protectors. |
1987-06-02 |
2023-08-11 |
rat |
| E L Rodríguez Echandía, S T Broitman, M R Fóscol. Effect of the chronic ingestion of chlorimipramine and desipramine on the hole board response to acute stresses in male rats. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:3575344. |
the baseline scores of hole board locomotion, head dipping, grooming and defecation were not affected by ds treatment but locomotion slightly increased in the ci treated group. |
1987-06-02 |
2023-08-11 |
rat |