| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dengyun Zhao, Yaping Guo, Huifang Wei, Xuechao Jia, Yafei Zhi, Guiliang He, Wenna Nie, Limeng Huang, Penglei Wang, Kyle Vaughn Laster, Zhicai Liu, Jinwu Wang, Mee-Hyun Lee, Zigang Dong, Kangdong Li. Multi-omics characterization of esophageal squamous cell carcinoma identifies molecular subtypes and therapeutic targets. JCI insight. 2024-04-23. PMID:38652547. |
in vitro and in vivo experiments further confirmed casein kinase ii subunit alpha (csnk2a1) as a potential kinase target for escc. |
2024-04-23 |
2024-04-26 |
Not clear |
| Zhengyao Yu, Huijuan He, Baoying Jiang, Jing H. O-GlcNAcylation of CSNK2A1 by OGT is Involved in the Progression of Colorectal Cancer. Molecular biotechnology. 2024-01-30. PMID:38289573. |
the casein kinase 2 alpha 1 (csnk2a1) is an oncogene involved in several cancers. |
2024-01-30 |
2024-02-01 |
mouse |
| Yangyang Zhang, Rui Kong, Wenbo Yang, Keyi Hu, Zhongjie Zhao, Le Li, Xinglong Geng, Liwei Liu, Hongze Chen, Peng Xiao, Danxi Liu, Yan Luo, Hua Chen, Jisheng Hu, Bei Su. DUSP2 recruits CSNK2A1 to suppress AKT1-mediated apoptosis resistance under hypoxic microenvironment in pancreatic cancer. Cancer letters. 2023-06-30. PMID:37390887. |
mechanistically, dusp2 competed with akt1 to bind to casein kinase 2 alpha 1 (csnk2a1) and inhibited the phosphorylation of akt1, which plays a crucial role in apoptosis resistance. |
2023-06-30 |
2023-08-14 |
Not clear |
| Jilong Li. P300 increases CSNK2A1 expression which accelerates colorectal cancer progression through activation of the PI3K-AKT-mTOR axis. Experimental cell research. 2023-06-30. PMID:37391010. |
casein kinase 2 alpha 1 (csnk2a1) is a known oncogene, but its role in the progression of colorectal cancer (crc) remain undefined. |
2023-06-30 |
2023-08-14 |
Not clear |
| Ioanna Ioannou, Angeliki Chatziantoniou, Constantinos Drenios, Panayiota Christodoulou, Malamati Kourti, Apostolos Zaravino. Signatures of Co-Deregulated Genes and Their Transcriptional Regulators in Kidney Cancers. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047552. |
differential expression and upstream regulators, including transcription factors [myc proto-oncogene (myc), ccaat enhancer binding protein delta (cebpd), rela proto-oncogene, nf-kb subunit (rela), zinc finger miz-type containing 1 (zmiz1), negative elongation factor complex member e (nelfe) and kruppel-like factor 4 (klf4)] and protein kinases [casein kinase 2 alpha 1 (csnk2a1), mitogen-activated protein kinases 1 (mapk1) and 14 (mapk14), sirtuin 1 (sirt1), cyclin dependent kinases 1 (cdk1) and 4 (cdk4), homeodomain interacting protein kinase 2 (hipk2) and extracellular signal-regulated kinases 1 and 2 (erk1/2)], were computed using the characteristic direction, as well as geo2enrichr and x2k, respectively, and further subjected to go and kegg pathways enrichment analyses. |
2023-04-13 |
2023-08-14 |
Not clear |
| Xiaoling Zhu, Jianguo Zhao, Jun X. Long noncoding RNA LINC01426 promotes the progression of lung adenocarcinoma via regulating miRNA-125a-5p/ casein kinase 2 alpha 1 axis. Bioengineered. vol 13. issue 3. 2022-03-10. PMID:35266446. |
moreover, casein kinase 2 alpha 1 (csnk2a1) was predicted to bind to mir-125a-5p. |
2022-03-10 |
2023-08-13 |
Not clear |
| Ruohao Wu, Wenting Tang, Kunyin Qiu, Pinggan Li, Yu Li, Dongfang Li, Zhanwen H. An Integrative Pan-Cancer Analysis of the Prognostic and Immunological Role of Casein Kinase 2 Alpha Protein 1 (CSNK2A1) in Human Cancers: A Study Based on Bioinformatics and Immunohistochemical Analysis. International journal of general medicine. vol 14. 2021-10-09. PMID:34621130. |
although emerging animal- or cell-based evidence supports the relationship between casein kinase 2 alpha protein 1 (csnk2a1) and cancers, no pan-cancer analysis is available. |
2021-10-09 |
2023-08-13 |
human |
| Ruohao Wu, Wenting Tang, Kunyin Qiu, Pinggan Li, Yu Li, Dongfang Li, Zhanwen H. An Integrative Pan-Cancer Analysis of the Prognostic and Immunological Role of Casein Kinase 2 Alpha Protein 1 (CSNK2A1) in Human Cancers: A Study Based on Bioinformatics and Immunohistochemical Analysis. International journal of general medicine. vol 14. 2021-10-09. PMID:34621130. |
an integrative pan-cancer analysis of the prognostic and immunological role of casein kinase 2 alpha protein 1 (csnk2a1) in human cancers: a study based on bioinformatics and immunohistochemical analysis. |
2021-10-09 |
2023-08-13 |
human |
| Ceris I Owen, Ramsay Bowden, Michael J Parker, Jo Patterson, Joan Patterson, Sue Price, Ajoy Sarkar, Bruce Castle, Charulatha Deshpande, Miranda Splitt, Neeti Ghali, John Dean, Andrew J Green, Charlene Crosby, Katrina Tatton-Brow. Extending the phenotype associated with the CSNK2A1-related Okur-Chung syndrome-A clinical study of 11 individuals. American journal of medical genetics. Part A. vol 176. issue 5. 2019-05-20. PMID:29383814. |
variants in the protein kinase ck2 alpha subunit, encoding the csnk2a1 gene, have previously been reported in children with an intellectual disability and dysmorphic facial features syndrome: now termed the okur-chung neurodevelopmental syndrome. |
2019-05-20 |
2023-08-13 |
Not clear |
| Harsh B Pathak, Yan Zhou, Geetika Sethi, Jeff Hirst, Russell J Schilder, Erica A Golemis, Andrew K Godwi. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. PloS one. vol 10. issue 12. 2016-06-27. PMID:26637171. |
of these, csnk2a1, which codes for the catalytic alpha subunit of protein kinase ck2, was selected for additional evaluation. |
2016-06-27 |
2023-08-13 |
Not clear |
| Katarzyna Mierzejewska, Jinbeom Heo, Jeong Wook Kang, Hyunsook Kang, Janina Ratajczak, Mariusz Z Ratajczak, Magda Kucia, Dong-Myung Shi. Genome-wide analysis of murine bone marrow‑derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells. International journal of molecular medicine. vol 32. issue 2. 2014-06-09. PMID:23708325. |
employing leading-edge subset analysis and real-time pcr assays, we observed that several genes, such as growth factor receptor-bound protein 2 (grb2), son of sevenless homolog 1 (sos1), shc (src homology 2 domain containing) transforming protein 1 (shc1), mitogen-activated protein kinase kinase 1 (map2k1), v-akt murine thymoma viral oncogene homolog 3 (akt3), elk1, ribosomal protein s6 kinase, 90 kda, polypeptide 3 (rps6ka3), glycogen synthase kinase 3β (gsk3β) and casein kinase 2, alpha 1 polypeptide (csnk2a1), which are involved in mitogenic growth factor signaling pathways, were commonly downregulated in the vsels. |
2014-06-09 |
2023-08-12 |
mouse |
| Zhuomin Wang, Hongyu Liu, Baoxing Liu, Wei Ma, Xingyang Xue, Jun Chen, Qinghua Zho. Gene expression levels of CSNK1A1 and AAC-11, but not NME1, in tumor tissues as prognostic factors in NSCLC patients. Medical science monitor : international medical journal of experimental and clinical research. vol 16. issue 8. 2010-11-03. PMID:20671611. |
to analyze the prognostic significance of the genes casein kinase 2 alpha subunit (csnk2a1), anti-apoptosis clone-11 (aac-11), and tumor metastasis suppressor nme1 in completely resected non-small cell lung cancer (nsclc) patients. |
2010-11-03 |
2023-08-12 |
Not clear |
| Jesús Lascorz, Asta Försti, Bowang Chen, Stephan Buch, Verena Steinke, Nils Rahner, Elke Holinski-Feder, Monika Morak, Hans K Schackert, Heike Görgens, Karsten Schulmann, Timm Goecke, Matthias Kloor, Cristoph Engel, Reinhard Büttner, Nelli Kunkel, Marianne Weires, Michael Hoffmeister, Barbara Pardini, Alessio Naccarati, Ludmila Vodickova, Jan Novotny, Stefan Schreiber, Michael Krawczak, Clemens D Bröring, Henry Völzke, Clemens Schafmayer, Pavel Vodicka, Jenny Chang-Claude, Hermann Brenner, Barbara Burwinkel, Peter Propping, Jochen Hampe, Kari Hemmink. Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. Carcinogenesis. vol 31. issue 9. 2010-09-30. PMID:20610541. |
two other unreported snps, rs6038071, 40 kb upstream of csnk2a1 (casein kinase 2, alpha 1 polypeptide) and an intronic marker in myo3a (myosin iiia), rs11014993, associated with crc only in the familial crc cases (p = 2.5 x 10(-3), recessive model, and p = 2.7 x 10(-4), dominant model). |
2010-09-30 |
2023-08-12 |
Not clear |
| U Wirkner, H Voss, W Ansorge, W Pyeri. Genomic organization and promoter identification of the human protein kinase CK2 catalytic subunit alpha (CSNK2A1). Genomics. vol 48. issue 1. 1998-04-24. PMID:9503018. |
genomic organization and promoter identification of the human protein kinase ck2 catalytic subunit alpha (csnk2a1). |
1998-04-24 |
2023-08-12 |
human |
| T L Yang-Feng, T Naiman, I Kopatz, D Eli, N Dafni, D Canaan. Assignment of the human casein kinase II alpha' subunit gene (CSNK2A1) to chromosome 16p13.2-p13.3. Genomics. vol 19. issue 1. 1994-06-21. PMID:8188223. |
assignment of the human casein kinase ii alpha' subunit gene (csnk2a1) to chromosome 16p13.2-p13.3. |
1994-06-21 |
2023-08-12 |
human |
| U Wirkner, H Voss, P Lichter, W Ansorge, W Pyeri. The human gene (CSNK2A1) coding for the casein kinase II subunit alpha is located on chromosome 20 and contains tandemly arranged Alu repeats. Genomics. vol 19. issue 2. 1994-06-20. PMID:8188256. |
we have isolated and characterized a 18.9-kb genomic clone representing a central portion of the human casein kinase ii (ckii) subunit alpha gene (csnk2a1). |
1994-06-20 |
2023-08-12 |
human |
| U Wirkner, H Voss, P Lichter, W Ansorge, W Pyeri. The human gene (CSNK2A1) coding for the casein kinase II subunit alpha is located on chromosome 20 and contains tandemly arranged Alu repeats. Genomics. vol 19. issue 2. 1994-06-20. PMID:8188256. |
the human gene (csnk2a1) coding for the casein kinase ii subunit alpha is located on chromosome 20 and contains tandemly arranged alu repeats. |
1994-06-20 |
2023-08-12 |
human |
| S Singh, I Jantke, M Simon, I Meybohm, B Boldyreff, O Issinger, H W Goedd. PstI identifies biallelic DNA polymorphism of the human casein kinase 2 alpha gene (CSNK2A1). Human genetics. vol 93. issue 4. 1994-06-01. PMID:7909530. |
psti identifies biallelic dna polymorphism of the human casein kinase 2 alpha gene (csnk2a1). |
1994-06-01 |
2023-08-12 |
human |