All Relations between elovl1 and microglial cell
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Sheng-Jie Hou, Ya-Ru Huang, Jie Zhu, Ying-Bo Jia, Xiao-Yun Niu, Jin-Ju Yang, Xiao-Lin Yu, Xiao-Yu Du, Shi-Yu Liang, Fang Cui, Ling-Jie Li, Chen Tian, Rui-Tian Li. Mouse serum albumin induces neuronal apoptosis and tauopathies. Acta neuropathologica communications. vol 12. issue 1. 2024-04-23. PMID:38654316. |
we here demonstrated that mouse serum albumin-activated microglia induced astrocytes to a1 phenotype to remarkably increase levels of elovl1, an astrocytic synthase for very long-chain saturated fatty acids, significantly promoting vlsfas secretion and causing neuronal lippoapoptosis through endoplasmic reticulum stress response pathway. |
2024-04-23 |
2024-04-26 |
mouse |