All Relations between fmr1 and astrocyte
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Danijela Bataveljic, Helena Pivonkova, Vidian de Concini, Betty Hébert, Pascal Ezan, Sylvain Briault, Alexis-Pierre Bemelmans, Jacques Pichon, Arnaud Menuet, Nathalie Rouac. Astroglial Kir4.1 potassium channel deficit drives neuronal hyperexcitability and behavioral defects in Fragile X syndrome mouse model. Nature communications. vol 15. issue 1. 2024-04-28. PMID:38678030. | viral delivery of kir4.1 channels specifically to hippocampal astrocytes from fmr1 knockout mice indeed rescues normal astrocyte potassium uptake, neuronal excitability, and cognitive and social performance. | 2024-04-28 | 2024-04-30 | mouse |
| Kathryn E Reynolds, Eileen Huang, Monica Sabbineni, Eliza Wiseman, Nadeem Murtaza, Desmond Ahuja, Matt Napier, Kathryn M Murphy, Karun K Singh, Angela L Scot. Purinergic Signalling Mediates Aberrant Excitability of Developing Neuronal Circuits in the Fmr1 Knockout Mouse Model. Molecular neurobiology. 2024-04-23. PMID:38652351. | in this study, we examined whether elevated astrocyte purinergic signalling also impacts neuronal morphology and connectivity of fmr1 ko cortical neurons. | 2024-04-23 | 2024-04-26 | mouse |
| Kathryn E Reynolds, Chloe R Wong, Angela L Scot. Astrocyte-mediated purinergic signaling is upregulated in a mouse model of Fragile X syndrome. Glia. vol 69. issue 7. 2021-05-11. PMID:33754385. | in primary astrocyte cultures derived from the fmr1 knockout (ko) mouse model of fxs, we found that application of exogenous atp and utp evoked elevated intracellular calcium responses compared to wildtype levels. | 2021-05-11 | 2023-08-13 | mouse |
| Zhengyu Cao, Susan Hulsizer, Yanjun Cui, Dalyir L Pretto, Kyung Ho Kim, Paul J Hagerman, Flora Tassone, Isaac N Pessa. Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion. The Journal of biological chemistry. vol 288. issue 19. 2013-07-12. PMID:23553633. | fmr1 cgg expansion repeats in the premutation range have not been linked to astrocyte pathophysiology. | 2013-07-12 | 2023-08-12 | Not clear |