| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chenxi Lu, Yanbin Song, Xiaopeng Wu, Wangrui Lei, Junmin Chen, Xin Zhang, Qiong Liu, Chao Deng, Zhenxing Liang, Ying Chen, Jun Ren, Yang Yan. Pleiotropic role of GAS6 in cardioprotection against ischemia-reperfusion injury. Journal of advanced research. 2024-04-23. PMID:38653371. |
growth arrest-specific gene 6 (gas6) is vitamin k-dependent secretory protein, to promote cell proliferation and inhibit inflammation and apoptosis through binding with tyro3, axl, and mertk (tam) receptors. |
2024-04-23 |
2024-04-26 |
Not clear |
| Niloufar Salehi, Mitra Nourbakhsh, Shokoofe Noori, Hossein Rezaeizadeh, Afshin Zargh. Tehranolid and Artemisinin Effects on Ameliorating Experimental Autoimmune Encephalomyelitis by Modulating Inflammation and Remyelination. Molecular neurobiology. 2023-06-30. PMID:37391648. |
the compounds made no changes in rorγt, nestin, gas6, tyro3, and mertk mrna expression levels in the spinal cord. |
2023-06-30 |
2023-08-14 |
mouse |
| Xiaochen Niu, Ye Cheng, Meng Zhang, Luyang Du, Xue Wu, Chenxi Lu, Xiyang Li, Shuai Liu, Aizhen Zhao, Shaofei Zhang, Zhen Wu, Baoping Ding, Wenzhen Shi, Changyu Wang, Yang Yang, Ye Tia. Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells. Frontiers in cell and developmental biology. vol 9. 2022-02-10. PMID:35141232. |
the biological functions of gas6 are mediated by the interaction with tam (tyro3, axl and mertk) receptors, including cell survival and proliferation, immune regulation and apoptosis. |
2022-02-10 |
2023-08-13 |
human |
| Yuanfeng Du, Zhangfan Lu, Dingbo Yang, Ding Wang, Li Jiang, Yongfeng Shen, Quan Du, Wenhua Y. MerTK inhibits the activation of the NLRP3 inflammasome after subarachnoid hemorrhage by inducing autophagy. Brain research. vol 1766. 2021-09-21. PMID:34010608. |
activating mertk with growth arrest-specific 6 (gas6) alleviated brain edema, neuronal degeneration and neurological deficits after sah by regulating neuroinflammation. |
2021-09-21 |
2023-08-13 |
mouse |
| Juwen C DuBois, Alex K Ray, Peter Davies, Bridget Shafit-Zagard. Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis. Journal of neuroinflammation. vol 17. issue 1. 2021-09-16. PMID:33121494. |
during experimental autoimmune encephalomyelitis (eae), the mrna expression of mertk, gas6, and axl significantly increase, whereas tyro3 and pros1 remain unchanged. |
2021-09-16 |
2023-08-13 |
Not clear |
| Rainer Akkermann, Andrea Aprico, Ashwyn A Perera, Helena Bujalka, Alistair E Cole, Junhua Xiao, Judith Field, Trevor J Kilpatrick, Michele D Binde. The TAM receptor Tyro3 regulates myelination in the central nervous system. Glia. vol 65. issue 4. 2018-01-12. PMID:28145605. |
we have previously identified that the protein gas6, a ligand for a family of tyrosine kinase receptors known as the tam (tyro3, axl, and mertk) receptors, directly increases oligodendrocyte induced myelination in vitro. |
2018-01-12 |
2023-08-13 |
Not clear |
| Ross C Gruber, Alex K Ray, Christopher T Johndrow, Hillary Guzik, Dominika Burek, Pablo García de Frutos, Bridget Shafit-Zagard. Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 49. 2015-02-19. PMID:25471571. |
during experimental autoimmune encephalomyelitis (eae), wild-type (wt) mice demonstrate a significant induction of gas6, axl, and mertk but not pros1 or tyro3 mrna. |
2015-02-19 |
2023-08-13 |
mouse |