| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vitoria K Paolillo, Matthew E Ochs, Erik A Lundquis. MAB-5/Hox regulates the Q neuroblast transcriptome, including cwn-1/Wnt, to mediate posterior migration in Caenorhabditis elegans. Genetics. 2024-04-23. PMID:38652773. |
one of these genes, cwn-1, acts downstream of mab-5 in ql migration, indicating that this gene set includes other genes utilized by mab-5 to facilitate posterior neuroblast migration. |
2024-04-23 |
2024-04-26 |
human |
| Wayne C Forrester, Changsung Kim, Gian Garrig. The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration. Genetics. vol 168. issue 4. 2005-06-21. PMID:15371357. |
through a canonical wnt signaling pathway, egl-20/wnt transcriptionally activates the hox gene mab-5 in the left q neuroblast and its descendants, causing the cells to migrate posteriorly. |
2005-06-21 |
2023-08-12 |
caenorhabditis_elegans |
| Wayne C Forrester, Changsung Kim, Gian Garrig. The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration. Genetics. vol 168. issue 4. 2005-06-21. PMID:15371357. |
the reversal in the migration of the left q neuroblast and its descendants resulted from a failure to express mab-5, an egl-20 mutant phenotype. |
2005-06-21 |
2023-08-12 |
caenorhabditis_elegans |
| Marie Silhánková, Marek Jindra, Masako Asahin. Nuclear receptor NHR-25 is required for cell-shape dynamics during epidermal differentiation in Caenorhabditis elegans. Journal of cell science. vol 118. issue Pt 1. 2005-06-09. PMID:15615786. |
unexpectedly, the lack of cell-cell contacts does not prevent a unique seam cell to produce a neuroblast, even though a homeotic gene (mab-5) that normally prevents the neuroblast commitment is ectopically expressed in the absence of nhr-25 function. |
2005-06-09 |
2023-08-12 |
caenorhabditis_elegans |
| Hendrik C Korswagen, Damien Y M Coudreuse, Marco C Betist, Sandra van de Water, Danica Zivkovic, Hans C Clever. The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans. Genes & development. vol 16. issue 10. 2002-06-26. PMID:12023307. |
we have shown previously that the egl-20/wnt-dependent expression of the homeobox gene mab-5 in the q neuroblast lineage requires bar-1/beta-catenin and pop-1/tcf. |
2002-06-26 |
2023-08-12 |
caenorhabditis_elegans |
| M Herma. C. elegans POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and in a noncanonical Wnt pathway that controls cell polarity. Development (Cambridge, England). vol 128. issue 4. 2001-03-29. PMID:11171341. |
wnt signaling by egl-20/wnt controls the migration of the descendants of the ql neuroblast by regulating the expression the hox gene mab-5. |
2001-03-29 |
2023-08-12 |
caenorhabditis_elegans |
| M A Herman, Q Ch'ng, S M Hettenbach, T M Ratliff, C Kenyon, R K Herma. EGL-27 is similar to a metastasis-associated factor and controls cell polarity and cell migration in C. elegans. Development (Cambridge, England). vol 126. issue 5. 1999-04-02. PMID:9927605. |
mutations in the c. elegans gene egl-27 cause defects in cell polarity and cell migration: the polarity of the asymmetric t cell division is disrupted and the descendants of the migratory ql neuroblast migrate incorrectly because they fail to express the hox gene mab-5. |
1999-04-02 |
2023-08-12 |
caenorhabditis_elegans |
| J N Maloof, J Whangbo, J M Harris, G D Jongeward, C Kenyo. A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. Development (Cambridge, England). vol 126. issue 1. 1999-02-22. PMID:9834184. |
here we report that egl-20, a c. elegans gene required to activate expression of the hox gene mab-5 in the migratory neuroblast ql, encodes a member of the wnt family of secreted glycoproteins. |
1999-02-22 |
2023-08-12 |
caenorhabditis_elegans |
| J N Maloof, J Whangbo, J M Harris, G D Jongeward, C Kenyo. A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. Development (Cambridge, England). vol 126. issue 1. 1999-02-22. PMID:9834184. |
we find that egl-20, pry-1 and bar-1 all function in a linear genetic pathway with conserved wnt signaling components, suggesting that a conserved wnt pathway activates expression of mab-5 in the migratory neuroblast ql. |
1999-02-22 |
2023-08-12 |
caenorhabditis_elegans |
| J Harris, L Honigberg, N Robinson, C Kenyo. Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position. Development (Cambridge, England). vol 122. issue 10. 1996-12-10. PMID:8898225. |
mab-5 expression switches on in the neuroblast ql as it migrates into the posterior body region. |
1996-12-10 |
2023-08-12 |
caenorhabditis_elegans |
| J Harris, L Honigberg, N Robinson, C Kenyo. Neuronal cell migration in C. elegans: regulation of Hox gene expression and cell position. Development (Cambridge, England). vol 122. issue 10. 1996-12-10. PMID:8898225. |
we address these questions by describing four genes, egl-20, mig-14, mig-1 and lin-17, that are required to activate expression of mab-5 during migration of the ql neuroblast. |
1996-12-10 |
2023-08-12 |
caenorhabditis_elegans |
| S J Salser, C Kenyo. A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis. Development (Cambridge, England). vol 122. issue 5. 1996-06-21. PMID:8625851. |
in one body region, mab-5 first switches on in a lineage to stimulate proliferation, then off to specify epidermal structures, then on in just one branch of the lineage to promote neuroblast formation, and finally off to permit proper sense organ morphology. |
1996-06-21 |
2023-08-12 |
caenorhabditis_elegans |
| J Austin, C Kenyo. Cell contact regulates neuroblast formation in the Caenorhabditis elegans lateral epidermis. Development (Cambridge, England). vol 120. issue 2. 1994-05-09. PMID:8149911. |
the effect of seam cell ablations on neuroblast formation is altered in mab-5(-) animals, suggesting that this hom-c gene is part of the pathway by which seam cell signaling controls the decision to make a postdeirid neuroblast. |
1994-05-09 |
2023-08-12 |
caenorhabditis_elegans |
| S J Salser, C Kenyo. Activation of a C. elegans Antennapedia homologue in migrating cells controls their direction of migration. Nature. vol 355. issue 6357. 1992-02-18. PMID:1346230. |
here we show that as one neuroblast migrates into this posterior region, it switches on mab-5 gene expression; mab-5 then acts as a developmental switch to control the migratory behaviour of the neuroblast descendants. |
1992-02-18 |
2023-08-11 |
caenorhabditis_elegans |