| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mosaad A Soltan, Ramdan S Shewita, Omaima A Matroud, Lamya Ahmed Alkeridis, Samy Sayed, Mustafa Shukry, Set A El-Shoboksh. Lignocellulose and probiotic supplementation in broiler chicken diet: effect on growth performance, digestive health, litter quality, and genes expression. Poultry science. vol 103. issue 6. 2024-04-23. PMID:38652957. |
dietary inclusion of lc and or b. subtilis supplementation significantly (p < 0.001) up-regulated hepatic growth-related genes (growth hormone receptor (ghr) and insulin growth factor1 (igf-1)) and antioxidant-related genes (superoxide dismutase 1 (sod1), glutathione peroxidase (gpx1) and uncoupling protein (ucp) and down-regulated (p < 0.001) splenic toll-like receptor 4 (tlrp) gene expression while had no significant effect on splenic interleukin 8 (il8) and tumor necrosis factor (tnf) with the best-obtained results with 1.0% followed by 0.5% lc with b. subtilis supplementation. |
2024-04-23 |
2024-04-26 |
chicken |
| Nada A Sallam, Baohua Wang, Ismail Lahe. Exercise training and vascular heterogeneity in db/db mice: evidence for regional- and duration-dependent effects. Naunyn-Schmiedeberg's archives of pharmacology. 2023-10-16. PMID:37843589. |
long-term et reduced body weight in parallel with reduced systemic inflammation and improved insulin sensitivity along with increased sod1, akt, and enos expression and improved no vasorelaxation. |
2023-10-16 |
2023-11-08 |
mouse |
| Anna Bizoń, Agata Tchórz, Paweł Madej, Marcin Leśniewski, Mariusz Wójtowicz, Agnieszka Piwowar, Grzegorz Frani. The Activity of Superoxide Dismutase, Its Relationship with the Concentration of Zinc and Copper and the Prevalence of rs2070424 Superoxide Dismutase Gene in Women with Polycystic Ovary Syndrome-Preliminary Study. Journal of clinical medicine. vol 11. issue 9. 2022-05-14. PMID:35566673. |
insulin resistance in the group of women with pcos caused a further sod1 activity decrease, while cu concentration and the value of cu/zn was increased when compared to women with normal insulin levels. |
2022-05-14 |
2023-08-13 |
Not clear |
| Łukasz Lewandowski, Iwona Urbanowicz, Marta Kepinska, Halina Milnerowic. Concentration/activity of superoxide dismutase isozymes and the pro-/antioxidative status, in context of type 2 diabetes and selected single nucleotide polymorphisms (genes: INS, SOD1, SOD2, SOD3) - Preliminary findings. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-20. PMID:33761612. |
moreover, many hereditary factors, including single-nucleotide polymorphisms (snps) of genes for coding insulin, insulin receptors, or insulin receptor substrates (ins, insr, irs1, irs2) or superoxide dismutase isozymes (sod1, sod2, sod3), have been linked with the incidence of obesity and diabetes. |
2021-07-20 |
2023-08-13 |
Not clear |
| Alastair D Green, Srividya Vasu, Neville H McClenaghan, Peter R Flat. Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells. Pflugers Archiv : European journal of physiology. vol 467. issue 10. 2016-06-27. PMID:25559846. |
measurement of gene expression by reverse-transcription, real-time pcr showed that genes involved with insulin secretion (ins, pdx1, pcsk1, pcsk2, glp1r and gipr), cell-cell communication (gjd2, gja1 and cdh1) and antioxidant defence (sod1, sod2, gpx1 and cat) were significantly upregulated in pseudoislets compared to monolayers, whilst the expression of proapoptotic genes (nos2, mapk8, mapk10 and nfkb1) showed no significant differences. |
2016-06-27 |
2023-08-13 |
human |
| Hidetaka Hamasaki, Yu Takeuchi, Yoshinori Masui, Yasuyuki Ohta, Koji Abe, Hiide Yoshino, Hidekatsu Yana. Development of diabetes in a familial amyotrophic lateral sclerosis patient carrying the I113T SOD1 mutation. Case Report. Neuro endocrinology letters. vol 36. issue 5. 2016-04-21. PMID:26707039. |
she may have developed diabetes due to sod1 dysfunction by the i113t sod1 mutation, and severe insulin resistance induced by als. |
2016-04-21 |
2023-08-13 |
mouse |
| Murat Giriş, Semra Doğru-Abbasoğlu, Alkın Kumral, Vakur Olgaç, Necla Koçak-Toker, Müjdat Uysa. Effect of carnosine alone or combined with α-tocopherol on hepatic steatosis and oxidative stress in fructose-induced insulin-resistant rats. Journal of physiology and biochemistry. vol 70. issue 2. 2015-01-02. PMID:24464863. |
insulin resistance, serum lipids, inflammation markers, hepatic lipids, lipid peroxides, and glutathione (gsh) levels together with glutathione peroxidase (gsh-px) and superoxide dismutase 1 (cuznsod; sod1) activities and their protein expressions were measured. |
2015-01-02 |
2023-08-12 |
rat |
| Giovanna Muscogiuri, Adam B Salmon, Cristina Aguayo-Mazzucato, Mengyao Li, Bogdan Balas, Rodolfo Guardado-Mendoza, Andrea Giaccari, Robert L Reddick, Sara M Reyna, Gordon Weir, Ralph A Defronzo, Holly Van Remmen, Nicolas Mus. Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function. Diabetes. vol 62. issue 12. 2014-01-17. PMID:24009256. |
genetic ablation of sod1 caused glucose intolerance, which was associated with reduced in vivo β-cell insulin secretion and decreased β-cell volume. |
2014-01-17 |
2023-08-12 |
mouse |
| Giovanna Muscogiuri, Adam B Salmon, Cristina Aguayo-Mazzucato, Mengyao Li, Bogdan Balas, Rodolfo Guardado-Mendoza, Andrea Giaccari, Robert L Reddick, Sara M Reyna, Gordon Weir, Ralph A Defronzo, Holly Van Remmen, Nicolas Mus. Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function. Diabetes. vol 62. issue 12. 2014-01-17. PMID:24009256. |
our findings suggest that oxidative stress per se does not play a major role in the pathogenesis of insulin resistance and demonstrate that oxidative stress caused by sod1 ablation leads to glucose intolerance secondary to β-cell dysfunction. |
2014-01-17 |
2023-08-12 |
mouse |
| Maivel H Ghattas, Dina M Abo-Elmatt. Association of polymorphic markers of the catalase and superoxide dismutase genes with type 2 diabetes mellitus. DNA and cell biology. vol 31. issue 11. 2013-01-18. PMID:22970972. |
genetic variants c1167t of cat gene and +35 a/c of sod1 gene has no role in insulin resistance in t2dm. |
2013-01-18 |
2023-08-12 |
human |
| Xiaodan Wang, Marko Z Vatamaniuk, Carol A Roneker, Matthew P Pepper, Liangbiao G Hu, Rebecca A Simmons, Xin Gen Le. Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity. Antioxidants & redox signaling. vol 14. issue 3. 2011-04-14. PMID:20586612. |
whereas the three knockout groups displayed decreased plasma insulin concentrations and islet β-cells mass, only sod1(-/-) showed decreased body weight, increased blood glucose, and blocked glucose-stimulated insulin secretion. |
2011-04-14 |
2023-08-12 |
mouse |
| Xiaodan Wang, Marko Z Vatamaniuk, Carol A Roneker, Matthew P Pepper, Liangbiao G Hu, Rebecca A Simmons, Xin Gen Le. Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity. Antioxidants & redox signaling. vol 14. issue 3. 2011-04-14. PMID:20586612. |
knockout of sod1 downregulated the foxhead box a2/pancreatic and duodenal homeobox 1 pathway in a superoxide-dependent fashion at epigenetic, mrna, and protein levels in islets, but improved insulin signaling in liver and muscle. |
2011-04-14 |
2023-08-12 |
mouse |
| Xin Gen Lei, Marko Z Vatamaniu. Two tales of antioxidant enzymes on β cells and diabetes. Antioxidants & redox signaling. vol 14. issue 3. 2011-04-14. PMID:20618069. |
although knockouts of gpx1 and sod1 each alone or together decreased pancreatic β cell mass and plasma insulin concentrations, these knockouts improved body insulin sensitivity to different extents. |
2011-04-14 |
2023-08-12 |
mouse |
| Takeshi Takazawa, Toshimasa Yamauchi, Atsushi Tsuchida, Makoto Takata, Yusuke Hada, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki, Takashi Kadowak. Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes. The Journal of biological chemistry. vol 284. issue 44. 2009-12-14. PMID:19706614. |
rosiglitazone ameliorated insulin sensitivity in both ob/ob mice and apoe-deficient ob/ob mice, possibly through decreasing the expression of monocyte chemoattractant protein-1 (mcp-1), increasing the expression of superoxide dismutase 1 (sod1) in wat, and increasing plasma adiponectin concentration. |
2009-12-14 |
2023-08-12 |
mouse |