All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and cerebellum

Publication Sentence Publish Date Extraction Date Species
Ning Chen, Nikhil J Pandya, Frank Koopmans, Violeta Castelo-Székelv, Roel C van der Schors, August B Smit, Ka Wan L. Interaction proteomics reveals brain region-specific AMPA receptor complexes. Journal of proteome research. vol 13. issue 12. 2015-10-26. PMID:25337787. here we examined the ampa receptor interactomes from cortex, hippocampus, and cerebellum by comprehensive interaction proteomics. 2015-10-26 2023-08-13 Not clear
Boeke J van Beugen, Xin Qiao, Dana H Simmons, Chris I De Zeeuw, Christian Hanse. Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 12. 2015-07-16. PMID:25403454. enhanced ampa receptor function promotes cerebellar long-term depression rather than potentiation. 2015-07-16 2023-08-13 Not clear
R Zwart, E Sher, X Ping, X Jin, J R Sims, A S Chappell, S D Gleason, P J Hahn, K Gardinier, D L Gernert, J Hobbs, J L Smith, S N Valli, J M Witki. Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models. The Journal of pharmacology and experimental therapeutics. vol 351. issue 1. 2014-11-25. PMID:25027316. we asked whether perampanel has ampa receptor antagonist activity in both the cerebral cortex and hippocampus associated with antiepileptic efficacy and also in the cerebellum associated with motor side effects in rodent and human brains. 2014-11-25 2023-08-13 human
R Zwart, E Sher, X Ping, X Jin, J R Sims, A S Chappell, S D Gleason, P J Hahn, K Gardinier, D L Gernert, J Hobbs, J L Smith, S N Valli, J M Witki. Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models. The Journal of pharmacology and experimental therapeutics. vol 351. issue 1. 2014-11-25. PMID:25027316. perampanel inhibited native rat and human ampa receptors from the hippocampus as well as the cerebellum that were reconstituted into xenopus oocytes. 2014-11-25 2023-08-13 human
Andreia Barateiro, Helena Sofia Domingues, Adelaide Fernandes, João Bettencourt Relvas, Dora Brite. Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors. Molecular neurobiology. vol 49. issue 1. 2014-10-27. PMID:23982745. rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by ampa and tnf-α inhibitors. 2014-10-27 2023-08-12 rat
Jessica A Loweth, Kuei Y Tseng, Marina E Wol. Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche. Current opinion in neurobiology. vol 23. issue 4. 2014-02-27. PMID:23385114. in several brain regions (ventral tegmental area (vta), cerebellum, and amygdala), stimulation of mglur1 selectively inhibits synaptic transmission mediated by calcium-permeable ampa receptors (cp-ampars) and thus produces synaptic depression. 2014-02-27 2023-08-12 Not clear
Smijin Soman, T R Anju, S Jayanarayanan, Sherin Antony, C S Paulos. Impaired motor learning attributed to altered AMPA receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of Withania somnifera and withanolide A. Epilepsy & behavior : E&B. vol 27. issue 3. 2013-12-09. PMID:23602240. impaired motor learning attributed to altered ampa receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of withania somnifera and withanolide a. 2013-12-09 2023-08-12 rat
Smijin Soman, T R Anju, S Jayanarayanan, Sherin Antony, C S Paulos. Impaired motor learning attributed to altered AMPA receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of Withania somnifera and withanolide A. Epilepsy & behavior : E&B. vol 27. issue 3. 2013-12-09. PMID:23602240. the aim of this study was to investigate the effect of withania somnifera (ws) extract, withanolide a (wa), and carbamazepine (cbz) on cerebellar ampa receptor function in pilocarpine-induced temporal lobe epilepsy (tle). 2013-12-09 2023-08-12 rat
Smijin Soman, T R Anju, S Jayanarayanan, Sherin Antony, C S Paulos. Impaired motor learning attributed to altered AMPA receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of Withania somnifera and withanolide A. Epilepsy & behavior : E&B. vol 27. issue 3. 2013-12-09. PMID:23602240. these findings suggest that ws and wa regulate ampa receptor function in the cerebellum of rats with tle, which has therapeutic application in epilepsy. 2013-12-09 2023-08-12 rat
Victor Anggono, Yeliz Koç-Schmitz, Jocelyn Widagdo, Jan Kormann, Annie Quan, Chih-Ming Chen, Phillip J Robinson, Se-Young Choi, David J Linden, Markus Plomann, Richard L Hugani. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 34. 2013-11-26. PMID:23918399. pick1 interacts with pacsin to regulate ampa receptor internalization and cerebellar long-term depression. 2013-11-26 2023-08-12 Not clear
Jens Schindler, Juanying Ye, Ole Nørregaard Jensen, Hans Gerd Nothwan. Monitoring the native phosphorylation state of plasma membrane proteins from a single mouse cerebellum. Journal of neuroscience methods. vol 213. issue 2. 2013-08-09. PMID:23246975. neuronal processing in the cerebellum involves the phosphorylation and dephosphorylation of various plasma membrane proteins such as ampa or nmda receptors. 2013-08-09 2023-08-12 mouse
Kazuhisa Kohda, Wataru Kakegawa, Shinji Matsuda, Tadashi Yamamoto, Hisashi Hirano, Michisuke Yuzak. The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 10. 2013-05-02. PMID:23431139. here, we show that the activity-dependent phosphorylation of serine 880 (s880) in glua2 ampa receptor subunit, which is an essential step for ampa receptor endocytosis during ltd induction, was impaired in glud2-null cerebellum. 2013-05-02 2023-08-12 Not clear
Andrea Cabrera-Pastor, Marta Llansola, Vitaliy Reznikov, Jordi Boix, Vicente Felip. Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo. Neurochemistry international. vol 61. issue 1. 2012-11-13. PMID:22521775. differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cgmp pathway by metabotropic glutamate receptor 5 and low and high affinity ampa receptors in cerebellum in vivo. 2012-11-13 2023-08-12 rat
Andrea Cabrera-Pastor, Marta Llansola, Vitaliy Reznikov, Jordi Boix, Vicente Felip. Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo. Neurochemistry international. vol 61. issue 1. 2012-11-13. PMID:22521775. the aim of this work was to assess whether hyperammonemia alters the modulation of this pathway by mglur5 and ampa receptors in cerebellum in vivo. 2012-11-13 2023-08-12 rat
Gabriela Antunes, Erik De Schutte. A stochastic signaling network mediates the probabilistic induction of cerebellar long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764236. cerebellar long-term depression (ltd) is a form of synaptic plasticity expressed as a reduction in the number of synaptic ampa receptors (ampars) in purkinje cells. 2012-09-18 2023-08-12 Not clear
Aiman S Saab, Alexander Neumeyer, Hannah M Jahn, Alexander Cupido, Antonia A M Šimek, Henk-Jan Boele, Anja Scheller, Karim Le Meur, Magdalena Götz, Hannah Monyer, Rolf Sprengel, Maria E Rubio, Joachim W Deitmer, Chris I De Zeeuw, Frank Kirchhof. Bergmann glial AMPA receptors are required for fine motor coordination. Science (New York, N.Y.). vol 337. issue 6095. 2012-09-13. PMID:22767895. in the cerebellum, bergmann glial (bg) cells express α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)-type glutamate receptors (ampars) composed exclusively of glua1 and/or glua4 subunits. 2012-09-13 2023-08-12 mouse
Rozzy Finn, Attila D Kovács, David A Pearc. Altered glutamate receptor function in the cerebellum of the Ppt1-/- mouse, a murine model of infantile neuronal ceroid lipofuscinosis. Journal of neuroscience research. vol 90. issue 2. 2012-08-23. PMID:21971706. western blotting of surface cross-linked cerebellar samples showed a significantly lower surface level of the glur4 ampa receptor subunit in ppt1(-/-) mice, providing a plausible explanation for the decreased vulnerability of ppt1(-/-) cerebellar neurons to ampa receptor-mediated cell death. 2012-08-23 2023-08-12 mouse
Toshihiro Nomura, Wataru Kakegawa, Shinji Matsuda, Kazuhisa Kohda, Jun Nishiyama, Takao Takahashi, Michisuke Yuzak. Cerebellar long-term depression requires dephosphorylation of TARP in Purkinje cells. The European journal of neuroscience. vol 35. issue 3. 2012-05-29. PMID:22239345. like hippocampal ltd, cerebellar ltd is mediated by the endocytosis of ampa (α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate) receptors at postsynaptic sites. 2012-05-29 2023-08-12 Not clear
Toshihiro Nomura, Wataru Kakegawa, Shinji Matsuda, Kazuhisa Kohda, Jun Nishiyama, Takao Takahashi, Michisuke Yuzak. Cerebellar long-term depression requires dephosphorylation of TARP in Purkinje cells. The European journal of neuroscience. vol 35. issue 3. 2012-05-29. PMID:22239345. activity-dependent dephosphorylation of stargazin (an ampa receptor auxiliary protein) by calcineurin regulates hippocampal ltd, but whether and how stargazin is involved in cerebellar ltd is unknown. 2012-05-29 2023-08-12 Not clear
Olga Shevtsova, Beulah Leitc. Selective loss of AMPA receptor subunits at inhibitory neuron synapses in the cerebellum of the ataxic stargazer mouse. Brain research. vol 1427. 2012-05-11. PMID:22055455. selective loss of ampa receptor subunits at inhibitory neuron synapses in the cerebellum of the ataxic stargazer mouse. 2012-05-11 2023-08-12 mouse