All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and cerebellum

Publication Sentence Publish Date Extraction Date Species
Richard M Bliss, Velvet Lee Finckbone, Jacquelyn Trice, Howard Strahlendorf, Jean Strahlendor. Tumor necrosis factor-α (TNF-α) augments AMPA-induced Purkinje neuron toxicity. Brain research. vol 1386. 2012-03-12. PMID:21276434. in a postnatal rat cerebellar slice model, we found that tnf-α exacerbated ampa-induced excitotoxicity in purkinje neurons in a dose-dependent manner beyond the toxicity caused by ampa alone. 2012-03-12 2023-08-12 rat
Jordi Boix, Marta Llansola, Andrea Cabrera-Pastor, Vicente Felip. Metabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors. Neurochemistry international. vol 58. issue 5. 2012-02-13. PMID:21300123. metabotropic glutamate receptor 5 modulates the nitric oxide-cgmp pathway in cerebellum in vivo through activation of ampa receptors. 2012-02-13 2023-08-12 rat
Jordi Boix, Marta Llansola, Andrea Cabrera-Pastor, Vicente Felip. Metabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors. Neurochemistry international. vol 58. issue 5. 2012-02-13. PMID:21300123. these data support that the three types of glutamate receptors: mglur5, ampa and nmda cooperate in the modulation of the grade and duration of activation of the no-cgmp pathway in cerebellum in vivo. 2012-02-13 2023-08-12 rat
Douglas A Schober, Martin B Gill, Hong Yu, Douglas L Gernert, Matthew W Jeffries, Paul L Ornstein, Akihiko S Kato, Christian C Felder, David S Bred. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of biological chemistry. vol 286. issue 15. 2011-06-28. PMID:21343286. we find that the cerebellar tarp, stargazin (γ-2), enhances the binding affinity of the ampa receptor potentiator [(3)h]-ly450295 and confers sensitivity to displacement by non-competitive antagonists. 2011-06-28 2023-08-12 mouse
Douglas A Schober, Martin B Gill, Hong Yu, Douglas L Gernert, Matthew W Jeffries, Paul L Ornstein, Akihiko S Kato, Christian C Felder, David S Bred. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of biological chemistry. vol 286. issue 15. 2011-06-28. PMID:21343286. autoradiography of [(3)h]-ly450295 binding to stargazer and γ-8-deficient mouse brain sections, demonstrates that tarps regulate the pharmacology of allosteric ampa potentiators and antagonists in the cerebellum and hippocampus, respectively. 2011-06-28 2023-08-12 mouse
Sang-Hun Lee, G Govindaiah, Charles L Co. Selective excitatory actions of DNQX and CNQX in rat thalamic neurons. Journal of neurophysiology. vol 103. issue 4. 2011-03-17. PMID:20107128. in this study, we examined whether quinoxaline derivatives alter the intrinsic properties of thalamic neurons in light of recent findings indicating that these compounds can alter neuronal excitability in hippocampal and cerebellar neurons via transmembrane ampa receptor (ampar) regulatory proteins (tarps). 2011-03-17 2023-08-12 rat
N Sagata, A Iwaki, T Aramaki, K Takao, S Kura, T Tsuzuki, R Kawakami, I Ito, T Kitamura, H Sugiyama, T Miyakawa, Y Fukumak. Comprehensive behavioural study of GluR4 knockout mice: implication in cognitive function. Genes, brain, and behavior. vol 9. issue 8. 2011-03-02. PMID:20662939. the glur4 subunit is highly expressed in the cerebellum and the early postnatal hippocampus and is thought to be involved in synaptic plasticity and the development of functional neural circuitry through the recruitment of other ampa receptor subunits. 2011-03-02 2023-08-12 mouse
Saju Balakrishnan, Claire Jackson, Noah Russell, Tomas C Bellam. Ectopic release sites lack fast vesicle recycling mechanisms, causing long-term depression of neuron-glial transmission in rat cerebellum. Glia. vol 59. issue 1. 2011-02-25. PMID:20967883. the role of such "ectopic" release is unclear, but in the cerebellar molecular layer it is thought to guide the processes of bergmann glia toward synaptic terminals through activation of glial α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (ampa) receptors. 2011-02-25 2023-08-12 rat
Maya Yamazaki, Masahiro Fukaya, Kouichi Hashimoto, Miwako Yamasaki, Mika Tsujita, Makoto Itakura, Manabu Abe, Rie Natsume, Masami Takahashi, Masanobu Kano, Kenji Sakimura, Masahiko Watanab. TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. The European journal of neuroscience. vol 31. issue 12. 2011-01-25. PMID:20529126. tarps gamma-2 and gamma-7 are essential for ampa receptor expression in the cerebellum. 2011-01-25 2023-08-12 mouse
Maya Yamazaki, Masahiro Fukaya, Kouichi Hashimoto, Miwako Yamasaki, Mika Tsujita, Makoto Itakura, Manabu Abe, Rie Natsume, Masami Takahashi, Masanobu Kano, Kenji Sakimura, Masahiko Watanab. TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. The European journal of neuroscience. vol 31. issue 12. 2011-01-25. PMID:20529126. in the present study, we pursued their roles in synaptic expression of cerebellar ampa receptors. 2011-01-25 2023-08-12 mouse
Maya Yamazaki, Masahiro Fukaya, Kouichi Hashimoto, Miwako Yamasaki, Mika Tsujita, Makoto Itakura, Manabu Abe, Rie Natsume, Masami Takahashi, Masanobu Kano, Kenji Sakimura, Masahiko Watanab. TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. The European journal of neuroscience. vol 31. issue 12. 2011-01-25. PMID:20529126. therefore, gamma-2 and gamma-7 cooperatively promote synaptic expression of cerebellar ampa receptors, and the latter also promotes glial expression. 2011-01-25 2023-08-12 mouse
Rüdiger Rudolf, Claudia Margarethe Bittins, Hans-Hermann Gerde. The role of myosin V in exocytosis and synaptic plasticity. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21077886. this review focuses on the role of myosin v in (i) axonal transport and stimulated exocytosis of large dense-core vesicles to regulate the secretion of neuroactive substances, (ii) tethering of the endoplasmic reticulum at cerebellar synapses to permit long-term depression, (iii) recycling of α-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa) receptors at hippocampal synapses during long-term potentiation, and (iv) recycling of nicotinic acetylcholine receptors at the neuromuscular junction. 2011-01-20 2023-08-12 Not clear
Joanna Giza, Michael J Urbanski, Francesca Prestori, Bhaswati Bandyopadhyay, Annie Yam, Victor Friedrich, Kevin Kelley, Egidio D'Angelo, Mitchell Goldfar. Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 44. 2010-12-08. PMID:21048139. experimental disruption of the ib2 gene in mice reduces ampa and enhances nmda receptor-mediated glutamatergic transmission in cerebellum, changes the morphology of purkinje cell dendritic arbors, and induces motor and cognitive deficits suggesting an autism phenotype. 2010-12-08 2023-08-12 mouse
Céline Auger, David Ogde. AMPA receptor activation controls type I metabotropic glutamate receptor signalling via a tyrosine kinase at parallel fibre-Purkinje cell synapses. The Journal of physiology. vol 588. issue Pt 16. 2010-12-07. PMID:20603338. metabotropic glutamate receptors type 1 (mglur1s) and ionotropic ampa receptors (ampars) are colocalized at parallel fibre (pf) to purkinje cell synapses of the cerebellum. 2010-12-07 2023-08-12 rat
Claire Jackson, Heidi C Welch, Tomas C Bellam. Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PloS one. vol 5. issue 8. 2010-11-04. PMID:20694145. the induction mechanism for ltp at this synapse is considered reciprocal to "classical" ltp at hippocampal ca1 pyramidal neurons: kinases promote increased trafficking of ampa receptors into the postsynaptic density in the hippocampus, whereas phosphatases decrease internalization of ampa receptors in the cerebellum. 2010-11-04 2023-08-12 Not clear
Raquel S Pires, Caroline C Real, Thiago S Folador, Nataly R Tellini, Andréa S Torrão, Luiz R G Britt. Differential response of AMPA and NMDA glutamate receptors of Purkinje cells to aging of the chicken cerebellum. Neuroscience letters. vol 478. issue 3. 2010-10-08. PMID:20466035. differential response of ampa and nmda glutamate receptors of purkinje cells to aging of the chicken cerebellum. 2010-10-08 2023-08-12 chicken
Raquel S Pires, Caroline C Real, Thiago S Folador, Nataly R Tellini, Andréa S Torrão, Luiz R G Britt. Differential response of AMPA and NMDA glutamate receptors of Purkinje cells to aging of the chicken cerebellum. Neuroscience letters. vol 478. issue 3. 2010-10-08. PMID:20466035. since the cerebellum and glutamatergic neurotransmission are involved in several of those functions, the present work aimed at studying the expression of ampa and nmda glutamate receptor subunits in the chick cerebellum during aging. 2010-10-08 2023-08-12 chicken
V V Grigor'ev, I V Serkov, B K Beznosko, T A Ivanova, N M Gretskaia, V V Bezuglov, S O Bachuri. [Influence of derivatives of arachidonic and docosohexaenic acids on AMPA receptors in Purkinje neurons and cognitive functions in mice]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 3. 2010-08-31. PMID:20583621. the effect of derivatives of arachidonic and docosahexaenoic acids on ampa receptors in purkinje cells from the rat cerebellum was studied using the patch-clamp electrophysiological method. 2010-08-31 2023-08-12 mouse
Sandra D Santos, Bruno Manadas, Carlos B Duarte, Ana Luísa Carvalh. Proteomic analysis of an interactome for long-form AMPA receptor subunits. Journal of proteome research. vol 9. issue 4. 2010-07-02. PMID:20131911. immunoprecipitation of glur4 and associated proteins was performed using rat cerebellum lysates and an heterologous systems overexpressing glur4 ampa receptor subunit. 2010-07-02 2023-08-12 rat
Orlando J Castejón, Michael E Daile. Immunohistochemistry of GluR1 subunits of AMPA receptors of rat cerebellar nerve cells. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 33. issue 2. 2010-06-22. PMID:19886034. immunohistochemistry of glur1 subunits of ampa receptors of rat cerebellar nerve cells. 2010-06-22 2023-08-12 rat