| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhicheng Chen, Jocelyn Stockwell, Francisco S Cayabya. Adenosine A1 Receptor-Mediated Endocytosis of AMPA Receptors Contributes to Impairments in Long-Term Potentiation (LTP) in the Middle-Aged Rat Hippocampus. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26700433. |
adenosine a1 receptor-mediated endocytosis of ampa receptors contributes to impairments in long-term potentiation (ltp) in the middle-aged rat hippocampus. |
2016-12-13 |
2023-08-13 |
rat |
| Zhicheng Chen, Jocelyn Stockwell, Francisco S Cayabya. Adenosine A1 Receptor-Mediated Endocytosis of AMPA Receptors Contributes to Impairments in Long-Term Potentiation (LTP) in the Middle-Aged Rat Hippocampus. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26700433. |
previous reports have shown increased extracellular adenosine in the aging brain, and we recently reported that activation of adenosine a1 receptors (a1rs) induces ampa receptor (ampar) internalization in rat hippocampus. |
2016-12-13 |
2023-08-13 |
rat |
| Walter E Babiec, Ryan Guglietta, Thomas J O'Del. Basal levels of AMPA receptor GluA1 subunit phosphorylation at threonine 840 and serine 845 in hippocampal neurons. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 4. 2016-12-13. PMID:26980779. |
basal levels of ampa receptor glua1 subunit phosphorylation at threonine 840 and serine 845 in hippocampal neurons. |
2016-12-13 |
2023-08-13 |
Not clear |
| Txomin Lalanne, Julia Oyrer, Adamo Mancino, Erica Gregor, Andrew Chung, Louis Huynh, Sasha Burwell, Jérôme Maheux, Mark Farrant, P Jesper Sjöströ. Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5. The Journal of physiology. vol 594. issue 4. 2016-11-04. PMID:26537662. |
in the hippocampus, calcium-permeable ampa receptors have been found in a restricted subset of neuronal types that inhibit other neurons, although their localization in the neocortex is less well understood. |
2016-11-04 |
2023-08-13 |
Not clear |
| B N Queenan, K J Lee, H Tan, R L Huganir, S Vicini, D T S Pa. Mapping homeostatic synaptic plasticity using cable properties of dendrites. Neuroscience. vol 315. 2016-10-19. PMID:26701298. |
our analysis indicates that young rat cortical neurons globally scale ampa receptor-mediated currents, while mature hippocampal neurons do not, revealing distinct homeostatic strategies between brain regions and developmental stages. |
2016-10-19 |
2023-08-13 |
rat |
| Jocelyn Stockwell, Zhicheng Chen, Mina Niazi, Siddarth Nosib, Francisco S Cayabya. Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. Neuropharmacology. vol 102. 2016-10-07. PMID:26626486. |
protein phosphatase role in adenosine a1 receptor-induced ampa receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. |
2016-10-07 |
2023-08-13 |
rat |
| Jocelyn Stockwell, Zhicheng Chen, Mina Niazi, Siddarth Nosib, Francisco S Cayabya. Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. Neuropharmacology. vol 102. 2016-10-07. PMID:26626486. |
we recently showed a novel mechanism by which a1r activation with n(6)-cyclopentyl adenosine (cpa) induced glua1 and glua2 ampa receptor (ampar) endocytosis and adenosine-induced persistent synaptic depression (apsd) in rat hippocampus. |
2016-10-07 |
2023-08-13 |
rat |
| J-R Hao, N Sun, L Lei, X-Y Li, B Yao, K Sun, R Hu, X Zhang, X-D Shi, C Ga. L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway. Cell death & disease. vol 6. 2016-09-14. PMID:26539912. |
l-spd could improve the hippocampus-dependent memory, surface expression of glutamate receptor a (glua1)-containing ampa receptors and spine density in hippocampus of app/ps1 transgenic mice. |
2016-09-14 |
2023-08-13 |
mouse |
| Assaf Yacobi, Yael Stern Bach, Michal Horowit. The protective effect of heat acclimation from hypoxic damage in the brain involves changes in the expression of glutamate receptors. Temperature (Austin, Tex.). vol 1. issue 1. 2016-09-01. PMID:27583282. |
within the brain, the hippocampal and frontal cortex neurons are the most sensitive to hypoxia and cell death is mainly caused by calcium influx via glutamate-gated ion channels, specifically nmda and ampa receptors. |
2016-09-01 |
2023-08-13 |
rat |
| Hui Xiong, Frédéric Cassé, Yang Zhou, Ming Zhou, Zhi-Qi Xiong, Marian Joëls, Stéphane Martin, Harm J Kruger. mTOR is essential for corticosteroid effects on hippocampal AMPA receptor function and fear memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 22. issue 12. 2016-08-23. PMID:26572647. |
mtor is essential for corticosteroid effects on hippocampal ampa receptor function and fear memory. |
2016-08-23 |
2023-08-13 |
Not clear |
| Anna Phan, Sarah Suschkov, Luke Molinaro, Kathryn Reynolds, Jennifer M Lymer, Craig D C Bailey, Lee-Ming Kow, Neil J MacLusky, Donald W Pfaff, Elena Choleri. Rapid increases in immature synapses parallel estrogen-induced hippocampal learning enhancements. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 52. 2016-08-16. PMID:26655342. |
surprisingly, estrogen-activated spinogenesis was associated with a decrease in ca1 hippocampal excitatory input, rapidly and transiently reducing ca1 ampa activity via a mechanism likely reflecting ampa receptor internalization and creation of silent or immature synapses. |
2016-08-16 |
2023-08-13 |
mouse |
| Michael P Maher, Nyantsz Wu, Suchitra Ravula, Michael K Ameriks, Brad M Savall, Changlu Liu, Brian Lord, Ryan M Wyatt, Jose A Matta, Christine Dugovic, Sujin Yun, Luc Ver Donck, Thomas Steckler, Alan D Wickenden, Nicholas I Carruthers, Timothy W Lovenber. Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8. The Journal of pharmacology and experimental therapeutics. vol 357. issue 2. 2016-08-16. PMID:26989142. |
jnj-55511118 is a novel tool for reversible ampa receptor inhibition, particularly within the hippocampus, with potential therapeutic utility as an anticonvulsant or neuroprotectant. |
2016-08-16 |
2023-08-13 |
Not clear |
| G B Christiansen, B Harbak, S E Hede, A H Gouliaev, L Olsen, K Frydenvang, J Egebjerg, J S Kastrup, M M Hol. A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures. Neuroscience. vol 310. 2016-08-15. PMID:26450748. |
a novel dualistic profile of an allosteric ampa receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures. |
2016-08-15 |
2023-08-13 |
mouse |
| Xinglong Gu, Xia Mao, Marc P Lussier, Mary Anne Hutchison, Liang Zhou, F Kent Hamra, Katherine W Roche, Wei L. GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons. Nature communications. vol 7. 2016-07-20. PMID:26932439. |
gsg1l suppresses ampa receptor-mediated synaptic transmission and uniquely modulates ampa receptor kinetics in hippocampal neurons. |
2016-07-20 |
2023-08-13 |
rat |
| Jing-Jing Duan, Adrian F Lozada, Chen-Yu Gou, Jing Xu, Yuan Chen, Darwin K Ber. Nicotine recruits glutamate receptors to postsynaptic sites. Molecular and cellular neurosciences. vol 68. 2016-07-11. PMID:26365992. |
we show here that chronic exposure of hippocampal neurons in culture to low levels of nicotine recruits ampa and nmda receptors to the cell surface and sequesters them at postsynaptic sites. |
2016-07-11 |
2023-08-13 |
Not clear |
| Bopanna I Kalappa, Charles T Anderson, Jacob M Goldberg, Stephen J Lippard, Thanos Tzounopoulo. AMPA receptor inhibition by synaptically released zinc. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 51. 2016-06-10. PMID:26647187. |
here we provide evidence that endogenous zinc, released by single presynaptic action potentials, inhibits synaptic ampa currents in the dorsal cochlear nucleus (dcn) and hippocampus. |
2016-06-10 |
2023-08-13 |
Not clear |
| Daniel J Whitcomb, Ellen L Hogg, Philip Regan, Thomas Piers, Priyanka Narayan, Garry Whitehead, Bryony L Winters, Dong-Hyun Kim, Eunjoon Kim, Peter St George-Hyslop, David Klenerman, Graham L Collingridge, Jihoon Jo, Kwangwook Ch. Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus. Scientific reports. vol 5. 2016-06-09. PMID:26055072. |
intracellular oligomeric amyloid-beta rapidly regulates glua1 subunit of ampa receptor in the hippocampus. |
2016-06-09 |
2023-08-13 |
Not clear |
| Hendrik Wesseling, Elizabeth J Want, Paul C Guest, Hassan Rahmoune, Elaine Holmes, Sabine Bah. Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model. Journal of proteome research. vol 14. issue 8. 2016-06-06. PMID:26043028. |
bioinformatic pathway analysis confirmed prominent abnormalities in nmda-receptor-associated pathways in both brain regions, as well as alterations in other neurotransmitter systems such as kainate, ampa, and gabaergic signaling in the hippocampus and in proteins associated with neurodegeneration. |
2016-06-06 |
2023-08-13 |
rat |
| Jun Li, Anping Chai, Lifang Wang, Yuanlin Ma, Zhiliu Wu, Hao Yu, Liwei Mei, Lin Lu, Chen Zhang, Weihua Yue, Lin Xu, Yi Rao, Dai Zhan. Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 50. 2016-06-03. PMID:26621702. |
genetic deletion or knockdown of p-rex1 in the ca1 region of the hippocampus in mice resulted in autism-like social behavior that was specifically linked to the defect of long-term depression (ltd) in the ca1 region through alteration of ampa receptor endocytosis mediated by the postsynaptic pp1α (protein phosphase 1α)-p-rex1-rac1 (ras-related c3 botulinum toxin substrate 1) signaling pathway. |
2016-06-03 |
2023-08-13 |
mouse |
| Rafael Lazo-Gómez, Ricardo Tapi. Motor Alterations Induced by Chronic 4-Aminopyridine Infusion in the Spinal Cord In vivo: Role of Glutamate and GABA Receptors. Frontiers in neuroscience. vol 10. 2016-05-31. PMID:27242406. |
in previous work we showed that stimulation of glutamate release from nerve endings by perfusion of the k(+)-channel blocker 4-aminopyridine (4-ap) in the rat hippocampus induces seizures and neurodegeneration, and that ampa infusion in the spinal cord produces paralysis and mn death. |
2016-05-31 |
2023-08-13 |
rat |