| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mirko Lehmann, Thomas Plieger, Martin Reuter, UlrichEttinge. Insights into the molecular genetic basis of individual differences in metacognition. Physiology & behavior. 2023-03-04. PMID:36870383. |
here, an initial step toward resolving this issue was undertaken by investigating functional polymorphisms from three genes of the dopaminergic or serotonergic systems (drd4, comt, and 5-httlpr) in relation to behaviorally assessed metacognition in six paradigms across three cognitive domains. |
2023-03-04 |
2023-08-14 |
Not clear |
| Osama Y Alshogran, Laith N Al-Eitan, Shoroq M Altawalbeh, Hatem A Ama. Association of DRD4 exon III and 5-HTTLPR VNTR genetic polymorphisms with psychiatric symptoms in hemodialysis patients. PloS one. vol 16. issue 3. 2021-10-13. PMID:33784353. |
given that the dopaminergic and serotonergic pathways are involved in the etiology of psychiatric disease, this study evaluated the genetic association of dopamine d4 receptor (drd4) and serotonin transporter (slc6a4) genes with psychiatric symptom susceptibility among hd patients. |
2021-10-13 |
2023-08-13 |
Not clear |
| Elisa M Trucco, Brian M Hicks, Sandra Villafuerte, Joel T Nigg, Margit Burmeister, Robert A Zucke. Temperament and externalizing behavior as mediators of genetic risk on adolescent substance use. Journal of abnormal psychology. vol 125. issue 4. 2017-03-09. PMID:26845260. |
polymorphisms across serotonergic (slc6a4, 5-httlpr), dopaminergic (drd4, u-vntr), noradrenergic (slc6a2, rs36021), and gabaergic (gabra2, rs279858; gabra6, rs3811995) genes were examined given prior support for associations with temperament, externalizing behavior, and substance use problems. |
2017-03-09 |
2023-08-13 |
Not clear |
| Lindsay N Douglas, Austen B McGuire, Ann M Manzardo, Merlin G Butle. High-resolution chromosome ideogram representation of recognized genes for bipolar disorder. Gene. vol 586. issue 1. 2017-01-03. PMID:27063557. |
the identified genes impacted a broad range of biological pathways and processes including cellular signaling pathways particularly camp and calcium (e.g., cacna1c, camk2a, camk2d, adcy1, adcy2); glutamatergic (e.g., grik1, grm3, grm7), dopaminergic (e.g., drd2, drd4, comt, maoa) and serotonergic (e.g., htr1a, htr2a, htr3b) neurotransmission; molecular transporters (e.g., slc39a3, slc6a3, slc8a1); and neuronal growth (e.g., bdnf, igfbp1, nrg1, nrg3). |
2017-01-03 |
2023-08-13 |
human |
| Z Naumovska, A K Nestorovska, A Filipce, Z Sterjev, K Brezovska, A Dimovski, L J Suturkov. Pharmacogenetics and antipsychotic treatment response. Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki). vol 36. issue 1. 2016-07-15. PMID:26076775. |
it highlights the most important findings about the impact of functional polymorphisms in genes coding the cyp450 metabolizing enzymes, abcb1 transporter gene, dopaminergic and serotonergic drug targets (drd2, drd3, drd4, 5-ht1, 5ht-2a, 5ht-2c, 5ht6) as well as genes responsible for metabolism of neurotransmitters and g signalling pathways (5-httlpr, bdnf, comt, rgs4) and points their role as potential biomarkers in everyday clinical practice. |
2016-07-15 |
2023-08-13 |
Not clear |
| A E Gareeva, K O Kinyasheva, D Yu Galaktionova, E T Sabirov, R G Valinourov, A V Chudinov, A S Zasedatelev, T V Nasedkina, E K Khusnutdinov. [Brain neurotransmitter systems gene Polymorphism: the Search for pharmacogenetic markers of efficacy of haloperidol in Russians and Tatars]. Molekuliarnaia biologiia. vol 49. issue 6. 2016-02-23. PMID:26710776. |
in this paper, we analyzed the association of nine polymorphic variants of five genes of dopaminergic and serotonergic systems drd4, htr2a, tph1, slc18a1, comt in russian and tatars patients living in the republic of bashkortostan (rb) with the efficiency of a typical antipsychotic haloperidol on the scale of positive and negative systems of panss. |
2016-02-23 |
2023-08-13 |
Not clear |
| Emrah Cayla. Biochemical and genetic analyses of childhood attention deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 6. 2013-04-09. PMID:22825876. |
to date, these studies have reported substantial evidence implicating several genes (dopaminergic: drd4, dat1, drd5, comt; noradrenergic: dbh, adra2a; serotonergic: 5-htt, htr1b, htr2a; cholinergic: chrna4, and central nervous system development pathway: snap25, bdnf) in the etiology of adhd. |
2013-04-09 |
2023-08-12 |
Not clear |
| Gabor Varga, Anna Szekely, Peter Antal, Peter Sarkozy, Zsofia Nemoda, Zsolt Demetrovics, Maria Sasvari-Szekel. Additive effects of serotonergic and dopaminergic polymorphisms on trait impulsivity. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 3. 2012-10-05. PMID:22259185. |
here we report an association study of both dopaminergic (comt rs4680, drd4 48 bp vntr, drd2/ankk1 rs1800497) and serotonergic (htr1a rs6925, htr1b rs13212041, slc6a4 5-httlpr) gene polymorphisms and trait impulsivity assessed with the barratt impulsiveness scale (bis-11) in a sample of 687 caucasian young adults. |
2012-10-05 |
2023-08-12 |
Not clear |
| A Heck, R Lieb, A Ellgas, H Pfister, S Lucae, D Roeske, B Pütz, B Müller-Myhsok, M Uhr, F Holsboer, M Isin. Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking. Genes, brain, and behavior. vol 8. issue 4. 2009-09-11. PMID:19566713. |
to overcome this limitation, we performed an extended genetic association study analyzing 17 serotonergic (slc6a4, htr1a, htr1b, htr2a, htr2c, htr3a, htr6, maoa, tph1, tph2) and dopaminergic genes (slc6a3, drd2, drd3, drd4, comt, maoa, th, dbh), which have been previously reported to be implicated with personality traits. |
2009-09-11 |
2023-08-12 |
Not clear |
| Cristian Patrick Zeni, Ana Paula Guimarães, Guilherme V Polanczyk, Julia P Genro, Tatiana Roman, Mara H Hutz, Luis Augusto Rohd. No significant association between response to methylphenidate and genes of the dopaminergic and serotonergic systems in a sample of Brazilian children with attention-deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 3. 2007-07-18. PMID:17171656. |
we assessed effects of polymorphisms in candidate dopaminergic (drd4, dat1) and serotonergic genes (htr1b, htr2a, and 5-htt) on the response to treatment in 111 patients for whom methylphenidate (mph) was prescribed. |
2007-07-18 |
2023-08-12 |
Not clear |
| Benno Graf Schimmelmann, Susann Friedel, Hanna Christiansen, Astrid Dempfle, Anke Hinney, Johannes Hebebran. [Genetic findings in Attention-Deficit and Hyperactivity Disorder (ADHD)]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 34. issue 6. 2007-01-29. PMID:17094061. |
meta-analyses of a large number of candidate gene studies suggest association with gene variants of the dopaminergic receptors drd4 and drd5, the serotonergic receptor htr1b, and the synaptosomal receptor protein (snap-25). |
2007-01-29 |
2023-08-12 |
Not clear |
| A Frisch, D Postilnick, R Rockah, E Michaelovsky, S Postilnick, E Birman, N Laor, B Rauchverger, A Kreinin, M Poyurovsky, M Schneidman, I Modai, R Weizma. Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways. Molecular psychiatry. vol 4. issue 4. 1999-10-18. PMID:10483058. |
in the present study, 102 unipolar mdd patients and 172 healthy controls were genotyped for polymorphisms in four serotonergic and three dopaminergic candidate genes [tryptophan hydroxylase (tph), serotonin receptor 2a (htr2a), serotonin receptor 2c (htr2c), serotonin transporter promoter region (5-httlpr), dopamine receptor d4 (drd4), dopamine transporter (dat1) and catechol-o-methyl transferase (comt)]. |
1999-10-18 |
2023-08-12 |
Not clear |