| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahmod Panahi, Yoshiki Hase, Xavier Gallart-Palau, Sumonto Mitra, Atsushi Watanabe, Roger C Low, Yumi Yamamoto, Diego Sepulveda-Falla, Atticus H Hainsworth, Masafumi Ihara, Siu Kwan Sze, Matti Viitanen, Homira Behbahani, Raj N Kalari. ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics. Acta neuropathologica communications. vol 11. issue 1. 2023-05-09. PMID:37158955. |
focusing on cerebral microvessels in the frontal and anterior temporal lobes and the basal ganglia, we used advanced proteomic and immunohistochemical methods to explore the extent of inflammatory and immune responses in cadasil subjects compared to similar age normal and other disease controls. |
2023-05-09 |
2023-08-14 |
human |
| Shino Magaki, Zesheng Chen, Alyscia Severance, Christopher K Williams, Ramiro Diaz, Chuo Fang, Negar Khanlou, William H Yong, Annlia Paganini-Hill, Rajesh N Kalaria, Harry V Vinters, Mark Fishe. Neuropathology of microbleeds in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Journal of neuropathology and experimental neurology. 2023-01-30. PMID:36715085. |
in this study, we characterized findings relevant to cmbs in autopsy brain tissue of 8 patients with genetically confirmed cadasil and 10 controls within the age range of the cadasil patients by assessing the distribution and extent of hemosiderin/iron deposits including perivascular hemosiderin leakage (pvh), capillary hemosiderin deposits, and parenchymal iron deposits (pid) in the frontal cortex and white matter, basal ganglia and cerebellum. |
2023-01-30 |
2023-08-14 |
human |
| Jessica Lisa Littau, Lina Velilla, Yoshiki Hase, Nelson David Villalba-Moreno, Christian Hagel, Dagmar Drexler, Santiago Osorio Restrepo, Andres Villegas, Francisco Lopera, Sergio Vargas, Markus Glatzel, Susanne Krasemann, Yakeel T Quiroz, Joseph F Arboleda-Velasquez, Rajesh Kalaria, Diego Sepulveda-Fall. Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease. Brain pathology (Zurich, Switzerland). 2022-06-13. PMID:35695802. |
in post-mortem studies, total svd pathology in cortical areas and basal ganglia was similar in psen1 fad and cadasil subjects, except for the feature of arteriosclerosis which was higher in cadasil subjects than in psen1 fad subjects. |
2022-06-13 |
2023-08-14 |
human |
| Fiona C Moreton, Marco Düring, Thanh Phan, Velandai Srikanth, Richard Beare, Xuya Huang, Eric Jouvent, Hugues Chabriat, Martin Dichgans, Keith W Mui. Arterial branching and basal ganglia lacunes: A study in pure small vessel disease. European stroke journal. vol 2. issue 3. 2021-09-24. PMID:31008320. |
we investigated the branching order of arterial vessels associated with basal ganglia lacunes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil), in order to improve the understanding of their pathogenesis in pure cerebral small vessel disease. |
2021-09-24 |
2023-08-13 |
Not clear |
| Chengyue Sun, Yue Wu, Chen Ling, Zhiying Xie, Qingle Kong, Xiaojing Fang, Jing An, Yunchuang Sun, Wei Zhang, Qi Yang, Zhaoxia Wang, Zihao Zhang, Yun Yua. Deep Gray Matter Iron Deposition and Its Relationship to Clinical Features in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Patients: A 7.0-T Magnetic Resonance Imaging Study. Stroke. vol 51. issue 6. 2020-09-14. PMID:32397933. |
the susceptibility of deep gray matter in basal ganglia region, including caudate nucleus, putamen, and thalamus, significantly increased with age or disease duration and positively correlated with small vessel disease scores in patients with cadasil. |
2020-09-14 |
2023-08-13 |
Not clear |
| Michele Ragno, Sandro Sanguigni, Antonio Manca, Luigi Pianese, Cristina Paci, Alfonso Berbellini, Valeria Cozzolino, Roberto Gobbato, Silvio Peluso, Giuseppe De Michel. Parkinsonism in a pair of monozygotic CADASIL twins sharing the R1006C mutation: a transcranial sonography study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 37. issue 6. 2017-01-12. PMID:26850715. |
for the first time in cadasil patients, we used transcranial sonography (tcs) to assess basal ganglia abnormalities. |
2017-01-12 |
2023-08-13 |
Not clear |
| Bhavesh Trikamji, Mariam Thomas, Gasser Hathout, Shrikant Mishr. An unusual case of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy with occipital lobe involvement. Annals of Indian Academy of Neurology. vol 19. issue 2. 2016-06-13. PMID:27293347. |
on imaging cadasil is characterized by symmetric involvement by confluent lesions located subcortically in the frontal and temporal lobes as well as in the insula, periventricularly, in the centrum semiovale, in the internal and external capsule, basal ganglia, and brain stem; with relative sparing of the fronto-orbital and the occipital subcortical regions. |
2016-06-13 |
2023-08-13 |
Not clear |
| Lucinda J L Craggs, Christian Hagel, Gregor Kuhlenbaeumer, Anne Borjesson-Hanson, Oluf Andersen, Matti Viitanen, Hannu Kalimo, Catriona A McLean, Janet Y Slade, Roslyn A Hall, Arthur E Oakley, Yumi Yamamoto, Vincent Deramecourt, Rajesh N Kalari. Quantitative vascular pathology and phenotyping familial and sporadic cerebral small vessel diseases. Brain pathology (Zurich, Switzerland). vol 23. issue 5. 2014-03-14. PMID:23387519. |
vascular pathology was most severe in cadasil, and varied with marginally greater severity in the basal ganglia compared to the frontal lobe. |
2014-03-14 |
2023-08-12 |
Not clear |
| Michael K Liem, Jeroen van der Grond, Maarten J Versluis, Joost Haan, Andrew G Webb, Michel D Ferrari, Mark A van Buchem, Saskia A J Lesnik Oberstei. Lenticulostriate arterial lumina are normal in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy: a high-field in vivo MRI study. Stroke. vol 41. issue 12. 2010-12-22. PMID:20966419. |
the aim of this study is to examine the luminal diameters of lenticulostriate arteries in living patients with cadasil and to investigate whether luminal narrowing is correlated with the number of lacunar infarcts in the basal ganglia. |
2010-12-22 |
2023-08-12 |
Not clear |
| Francoise Gray, Marc Polivka, Anand Viswanathan, Marie Baudrimont, Marie-Germaine Bousser, Hugues Chabria. Apoptosis in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of neuropathology and experimental neurology. vol 66. issue 7. 2007-08-31. PMID:17620985. |
to test the hypothesis that an apoptotic process plays a role in the pathogenesis of cerebral lesions in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil), we examined samples from frontal, temporal, insular, and occipital regions, basal ganglia, and cerebellum from 4 patients with cadasil, 2 with binswanger disease, and 3 controls. |
2007-08-31 |
2023-08-12 |
Not clear |
| Francoise Gray, Marc Polivka, Anand Viswanathan, Marie Baudrimont, Marie-Germaine Bousser, Hugues Chabria. Apoptosis in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of neuropathology and experimental neurology. vol 66. issue 7. 2007-08-31. PMID:17620985. |
apoptosis of vascular cells was markedly increased in status cribrosus in cadasil, both in basal ganglia and subcortical white matter, suggesting that concomitantly with notch3 deposition it may play a causative role in the dilatation of virchow-robin spaces. |
2007-08-31 |
2023-08-12 |
Not clear |
| R Cumurciuc, J-P Guichard, D Reizine, F Gray, M G Bousser, H Chabria. Dilation of Virchow-Robin spaces in CADASIL. European journal of neurology. vol 13. issue 2. 2006-05-09. PMID:16490051. |
dilated vrs are frequent in cadasil and mostly located in the temporal white matter and basal ganglia. |
2006-05-09 |
2023-08-12 |
Not clear |
| A Panagariya, Bhawana Sharma, Shubhakara. CADASIL in a family from north-west India. The Journal of the Association of Physicians of India. vol 52. 2005-02-10. PMID:15645988. |
neuroimaging revealed diffuse hyperintense signals in subcortical white matter and basal ganglia on mr images in younger sib suggestive of cerebral autosomal dominant arteriopathy with sub-cortical infarcts and leucoencephalopathy (cadasil). |
2005-02-10 |
2023-08-12 |
Not clear |
| Koji Abe, Tetsuro Murakami, Etsuro Matsubara, Yasuhiro Manabe, Isao Nagano, Mikio Shoj. Clinical Features of CADASIL. Annals of the New York Academy of Sciences. vol 977. 2003-01-21. PMID:12480760. |
besides those in white matter and basal ganglia, ischemic lesions in temporal edge and corpus callosum were present on magnetic resonance images, which seemed to be characteristic of cadasil. |
2003-01-21 |
2023-08-12 |
human |
| M M Ruchoux, C A Maurag. CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of neuropathology and experimental neurology. vol 56. issue 9. 1997-10-15. PMID:9291937. |
the pathological data first dealt with the white matter and the basal ganglia showing the features observed in binswanger's subcortical arteriopathic encephalopathy; over the past few years, cadasil has become appreciated as a systemic vascular disease with specific features. |
1997-10-15 |
2023-08-12 |
Not clear |
| P Hedera, R P Friedlan. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: study of two American families with predominant dementia. Journal of the neurological sciences. vol 146. issue 1. 1997-06-19. PMID:9077492. |
our study of two american families with cadasil suggests that involvement of the basal ganglia and thalamus is important for early development of dementia and clinically can present as a gradual dementia, resembling a neurodegenerative process. |
1997-06-19 |
2023-08-12 |
human |
| M Vérin, Y Rolland, F Landgraf, H Chabriat, B Bompais, A Michel, K Vahedi, J P Martinet, E Tournier-Lasserve, M H Lemaitr. New phenotype of the cerebral autosomal dominant arteriopathy mapped to chromosome 19: migraine as the prominent clinical feature. Journal of neurology, neurosurgery, and psychiatry. vol 59. issue 6. 1996-01-18. PMID:7500094. |
the natural history suggests a chronological clinicoradiological staging of this phenotype of cadasil: stage i between 20 and 40 years with frequent migraine-like episodes and well delineated lesions of the white matter; stage ii between 40 and 60 years with stroke-like episodes, bipolar or monopolar-like psychotic disorders, coalescent lesions of the white matter, and well delineated lesions of the basal ganglia; and stage iii over 60 years with subcortical dementia, pseudobulbar palsy, diffuse leukoencephalopathy, and multiple well delineated lesions of the basal ganglia. |
1996-01-18 |
2023-08-12 |
Not clear |