| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rose Gelineau-Morel, Nomazulu Dlamini, Joel Bruss, Alexander Li Cohen, Amanda Robertson, Dimitrios Alexopoulos, Christopher D Smyser, Aaron D Boe. Network localization of pediatric lesion-induced dystonia. medRxiv : the preprint server for health sciences. 2024-04-22. PMID:38645071. |
classically dystonia has been thought of as a disorder of the basal ganglia, but newer results in idiopathic dystonia and lesion-induced dystonia in adults point to broader motor network dysfunction spanning the basal ganglia, cerebellum, premotor cortex, sensorimotor, and frontoparietal regions. |
2024-04-22 |
2024-04-24 |
Not clear |
| Taku Matsuda, Ryoma Morigaki, Hiroaki Hayasawa, Hiroshi Koyama, Teruo Oda, Kazuhisa Miyake, Yasushi Takag. Striatal parvalbumin interneurons, not cholinergic interneurons, are activated in a mouse model of cerebellar dystonia. Disease models & mechanisms. 2024-04-15. PMID:38616770. |
dystonia is supposed to arise from abnormalities in the motor loop of the basal ganglia; however, there is an ongoing debate regarding cerebellar involvement. |
2024-04-15 |
2024-04-17 |
mouse |
| Clément Tarrano, Cécile Galléa, Cécile Delorme, Eavan M McGovern, Cyril Atkinson-Clement, Isaac Jarratt Barnham, Vanessa Brochard, Stéphane Thobois, Christine Tranchant, David Grabli, Bertrand Degos, Jean Christophe Corvol, Jean-Michel Pedespan, Pierre Krystkowiak, Jean-Luc Houeto, Adrian Degardin, Luc Defebvre, Romain Valabrègue, Benoit Beranger, Emmanuelle Apartis, Marie Vidailhet, Emmanuel Roze, Yulia Worb. Association of abnormal explicit sense of agency with cerebellar impairment in myoclonus-dystonia. Brain communications. vol 6. issue 2. 2024-04-11. PMID:38601915. |
among various brain structures, the cerebral cortex, the cerebellum, and the basal ganglia are involved in shaping the sense of agency. |
2024-04-11 |
2024-04-13 |
Not clear |
| N Déglo. Gene editing as a therapeutic strategy for spinocerebellar ataxia type-3. Revue neurologique. 2024-04-05. PMID:38580500. |
clinically, sca3 pathology is characterized by progressive ataxia leading to motor incoordination that may affect balance, gait and speech, and neuropathologically by a progressive degeneration of the spinal cord and cerebellum, as well as the cerebral cortex and basal ganglia. |
2024-04-05 |
2024-04-10 |
Not clear |
| Noga Larry, Gil Zur, Mati Joshu. Organization of reward and movement signals in the basal ganglia and cerebellum. Nature communications. vol 15. issue 1. 2024-03-08. PMID:38459003. |
organization of reward and movement signals in the basal ganglia and cerebellum. |
2024-03-08 |
2024-03-11 |
monkey |
| Noga Larry, Gil Zur, Mati Joshu. Organization of reward and movement signals in the basal ganglia and cerebellum. Nature communications. vol 15. issue 1. 2024-03-08. PMID:38459003. |
the basal ganglia have been cast as the reward center of the motor system, whereas the cerebellum is thought to be involved in adjusting sensorimotor parameters. |
2024-03-08 |
2024-03-11 |
monkey |
| Noga Larry, Gil Zur, Mati Joshu. Organization of reward and movement signals in the basal ganglia and cerebellum. Nature communications. vol 15. issue 1. 2024-03-08. PMID:38459003. |
reward expectation and movement signals were the most pronounced in the output structure of the basal ganglia, intermediate in the cerebellum, and the smallest in the input structure of the basal ganglia. |
2024-03-08 |
2024-03-11 |
monkey |
| Noga Larry, Gil Zur, Mati Joshu. Organization of reward and movement signals in the basal ganglia and cerebellum. Nature communications. vol 15. issue 1. 2024-03-08. PMID:38459003. |
these findings suggest that reward and movement information is sharpened through the basal ganglia, resulting in a higher signal-to-noise ratio than in the cerebellum. |
2024-03-08 |
2024-03-11 |
monkey |
| Mauliza Mauliza, Herlina Dimiati, Muslim Akmal, Imran Imra. Role of forkhead box protein 2 (FOXP2) in oral-motor abilities of preterm infants: A brief literature review. Narra J. vol 3. issue 2. 2024-03-07. PMID:38450264. |
the oral feeding development involves forkhead box protein 2 (foxp2)-expressing neurons that are found in the deep layers of the cortex, basal ganglia, parts of the thalamus and purkinje cells of the cerebellum. |
2024-03-07 |
2024-03-09 |
Not clear |
| Cerebellar projections to the substantia nigra modulate basal ganglia dopamine levels. Nature neuroscience. 2024-01-31. PMID:38297081. |
cerebellar projections to the substantia nigra modulate basal ganglia dopamine levels. |
2024-01-31 |
2024-02-03 |
Not clear |
| Jason S Gill, Megan X Nguyen, Mariam Hull, Meike E van der Heijden, Ken Nguyen, Sruthi P Thomas, Roy V Sillito. Function and dysfunction of the dystonia network: an exploration of neural circuits that underlie the acquired and isolated dystonias. Dystonia. vol 2. 2024-01-26. PMID:38273865. |
an increasing number of investigations have tied this disorder to dysfunction of a broad "dystonia network" encompassing the cerebellum, thalamus, basal ganglia, and cortex. |
2024-01-26 |
2024-01-28 |
mouse |
| Samantha Washburn, Maritza Oñate, Junichi Yoshida, Jorge Vera, Ramakrishnan Bhuvanasundaram, Leila Khatami, Farzan Nadim, Kamran Khodakha. The cerebellum directly modulates the substantia nigra dopaminergic activity. Nature neuroscience. 2024-01-25. PMID:38272967. |
thus, the cerebellum directly, rapidly and effectively modulates basal ganglia dopamine levels and conveys information related to movement initiation, vigor and reward processing. |
2024-01-25 |
2024-01-28 |
mouse |
| Jonathan Nicholas, Christian Amlang, Chi-Ying R Lin, Leila Montaser-Kouhsari, Natasha Desai, Ming-Kai Pan, Sheng-Han Kuo, Daphna Shoham. The Role of the Cerebellum in Learning to Predict Reward: Evidence from Cerebellar Ataxia. Cerebellum (London, England). 2023-12-08. PMID:38066397. |
more broadly, the findings suggest that alongside its role in motor learning, the cerebellum likely operates in concert with the basal ganglia to support reinforcement learning from reward. |
2023-12-08 |
2023-12-17 |
human |
| Muhammad Hayyan Wazir, Yamna Ali, Ahmad Z Mufti, Alvina Ahmad, Hasnain Ahma. Fahr's Syndrome: A Rare Case Presentation. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022014. |
the interictal electroencephalogram was normal, and ct imaging of the brain without contrast revealed bilateral symmetrical dense calcifications in the basal ganglia, thalami, periventricular area, corona radiata, centrum semiovale, and dentate nucleus of the cerebellum, suggestive of fahr disease. |
2023-12-01 |
2023-12-07 |
Not clear |
| Muhammad Hayyan Wazir, Yamna Ali, Ahmad Z Mufti, Alvina Ahmad, Hasnain Ahma. Fahr's Syndrome: A Rare Case Presentation. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022014. |
the interictal electroencephalogram was normal, and ct imaging of the brain without contrast revealed bilateral symmetrical dense calcifications in the basal ganglia, thalami, periventricular area, corona radiata, centrum semiovale, and dentate nucleus of the cerebellum, suggestive of fahr disease. |
2023-11-29 |
2023-12-07 |
Not clear |
| Pei-Chen Hsieh, Pei Shan Yu, Wen-Lang Fan, Chun-Chieh Wang, Chih-Ying Chao, Yih-Ru W. A new phenotype of TUBB4A mutation in a family with adult-onset progressive spastic paraplegia and isolated hypomyelination leukodystrophy: A case report and literature review. Journal of movement disorders. 2023-10-23. PMID:37867417. |
tubulin beta 4a class iva (tubb4a) spectrum disorders have been reported as autosomal dominant dystonia type 4 or hypomyelination with atrophy of the basal ganglia and cerebellum (h-abc syndrome). |
2023-10-23 |
2023-11-08 |
Not clear |
| Daisuke Hatta, Kaito Kanamoto, Shiho Makiya, Kaori Watanabe, Tatsuya Kishino, Akira Kinoshita, Koh-Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwat. Proline-rich transmembrane protein 2 knock-in mice present dopamine-dependent motor deficits. Journal of biochemistry. 2023-10-04. PMID:37793168. |
although previous studies have shown that pkd might be caused by cerebellar dysfunction, prrt2 has not been sufficiently analyzed in some motor-related regions including the basal ganglia, where dopaminergic neurons are most abundant in the brain. |
2023-10-04 |
2023-10-07 |
mouse |
| Mirja Thomsen, Lara M Lange, Michael Zech, Katja Lohman. Genetics and Pathogenesis of Dystonia. Annual review of pathology. 2023-09-22. PMID:37738511. |
it has become clear that dystonia results from a dysfunctional network involving the basal ganglia, cerebellum, thalamus, and cortex. |
2023-09-22 |
2023-10-07 |
Not clear |
| Cagri Yurtsever, Jessica Harris, Alex Breeser, Sudha Ramachandran, Leszek Pisinsk. CHANTER Syndrome and mesenteric ischemia presenting concurrently, a case report and literature review. Radiology case reports. vol 18. issue 11. 2023-09-21. PMID:37732003. |
we present a case of a 70-year-old male who was brought to the hospital with altered mental status and was found to have 2 serious complications of cocaine use which are cerebellar hippocampal and basal nuclei transient edema with restricted diffusion (chanter) syndrome and mesenteric ischemia. |
2023-09-21 |
2023-10-07 |
Not clear |
| Paula A Zamudio, Dominic Gioia, Christina Glaser, John J Woodwar. Chemogenetic perturbation of the posterior but not anterior cerebellum reduces voluntary ethanol consumption. eNeuro. 2023-09-07. PMID:37679043. |
the cerebellum communicates with brain areas critically involved in control of goal-directed behaviors including the prefrontal and orbitofrontal cortices and midbrain and basal ganglia structures. |
2023-09-07 |
2023-10-07 |
mouse |