| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sudarshan Patil, Kleanthi Chalkiadaki, Tadiwos F Mergiya, Konstanze Krimbacher, Inês S Amorim, Shreeram Akerkar, Christos G Gkogkas, Clive R Bramha. eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance. iScience. vol 26. issue 5. 2023-05-30. PMID:37250335. |
eif4e phosphorylation recruits β-catenin to mrna cap and promotes wnt pathway translation in dentate gyrus ltp maintenance. |
2023-05-30 |
2023-08-14 |
Not clear |
| Raly James Perez Custodio, Hee Jin Kim, Jiyeon Kim, Darlene Mae Ortiz, Mikyung Kim, Danilo Buctot, Leandro Val Sayson, Hyun Jun Lee, Bung-Nyun Kim, Eugene C Yi, Jae Hoon Cheon. Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model. Communications biology. vol 6. issue 1. 2023-01-16. PMID:36646879. |
compared with thrsp knockout (ko) mice, thrsp oe mice showed impaired attention and memory, accompanied by dysregulated wnt signaling affecting hippocampal dentate gyrus cell proliferation and expression of markers for neural stem cell (nsc) activity. |
2023-01-16 |
2023-08-14 |
mouse |
| Keagan Dunville, Fabrizio Tonelli, Elena Novelli, Azzurra Codino, Verediana Massa, Anna Maria Frontino, Silvia Galfrè, Francesca Biondi, Stefano Gustincich, Matteo Caleo, Luca Pandolfini, Claudia Alia, Federico Cremis. Laminin511 and WNT signalling sustain prolonged expansion of hiPSC-derived hippocampal progenitors. Development (Cambridge, England). 2022-08-22. PMID:35993299. |
by the timely re-activation of wnt signalling in neuralizing hipscs, we produced neural progenitor cells with a gene expression profile typical of human embryonic dentate gyrus (dg) cells. |
2022-08-22 |
2023-08-14 |
mouse |
| Jiaqi Sun, Michael A Bonaguidi, Heechul Jun, Junjie U Guo, Gerald J Sun, Brett Will, Zhengang Yang, Mi-Hyeon Jang, Hongjun Song, Guo-li Ming, Kimberly M Christia. A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation. Molecular brain. vol 8. 2016-04-07. PMID:26337530. |
we previously identified a niche mechanism regulating proliferation and neuronal development in the adult mouse dentate gyrus resulting from the activity-regulated expression of secreted frizzled-related protein 3 (sfrp3) by mature neurons, which suppresses activation of radial glia-like neural stem cells (rgls) through inhibition of wingless/int (wnt) protein signaling. |
2016-04-07 |
2023-08-13 |
mouse |
| Se Hee Oh, Ha Na Kim, Hyun-Jung Park, Jin Young Shin, Phil Hyu Le. Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model. Cell transplantation. vol 24. issue 6. 2016-03-07. PMID:24612635. |
neurogenesis in the subgranular zone of the hippocampal dentate gyrus may act as an endogenous repair mechanism in alzheimer's disease (ad), and the wnt signaling pathway has been suggested to closely modulate neurogenesis in amyloid-β (aβ)-related ad models. |
2016-03-07 |
2023-08-12 |
Not clear |
| Youngshik Choe, Samuel J Pleasur. Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression. Developmental neuroscience. vol 34. issue 6. 2013-09-19. PMID:23257686. |
this suggests that wnt activation of dentate gyrus progenitors induces cxcl12 signaling by regulating receptor expression. |
2013-09-19 |
2023-08-12 |
mouse |
| Youngshik Choe, Samuel J Pleasur. Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression. Developmental neuroscience. vol 34. issue 6. 2013-09-19. PMID:23257686. |
wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating cxcr4 expression. |
2013-09-19 |
2023-08-12 |
mouse |
| Youngshik Choe, Samuel J Pleasur. Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression. Developmental neuroscience. vol 34. issue 6. 2013-09-19. PMID:23257686. |
we examined potential targets of the wnt pathway in these cells and found that cxcr4 is a direct target of lef1 in dentate gyrus progenitors and that loss of cxcr4 in postnatal neurogenesis decreases the production of ipcs. |
2013-09-19 |
2023-08-12 |
mouse |
| D U Kumar, H Devara. Expression of Wnt 3a, β-catenin, cyclin D1 and PCNA in mouse dentate gyrus subgranular zone (SGZ): a possible role of Wnt pathway in SGZ neural stem cell proliferation. Folia biologica. vol 58. issue 3. 2013-01-08. PMID:22849861. |
expression of wnt 3a, β-catenin, cyclin d1 and pcna in mouse dentate gyrus subgranular zone (sgz): a possible role of wnt pathway in sgz neural stem cell proliferation. |
2013-01-08 |
2023-08-12 |
mouse |
| Sebastian Jessberger, Robert E Clark, Nicola J Broadbent, Gregory D Clemenson, Antonella Consiglio, D Chichung Lie, Larry R Squire, Fred H Gag. Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learning & memory (Cold Spring Harbor, N.Y.). vol 16. issue 2. 2009-05-11. PMID:19181621. |
we here used a lentiviral approach to specifically block neurogenesis in the dentate gyrus of adult male rats by inhibiting wnt signaling, which is critically involved in the generation of newborn neurons, using a dominant-negative wnt (dnwnt). |
2009-05-11 |
2023-08-12 |
rat |
| Nina Solberg, Ondrej Machon, Stefan Kraus. Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. Developmental dynamics : an official publication of the American Association of Anatomists. vol 237. issue 7. 2008-12-10. PMID:18521945. |
effect of canonical wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. |
2008-12-10 |
2023-08-12 |
mouse |
| Ondrej Machon, Mattias Backman, Olga Machonova, Zbynek Kozmik, Tomas Vacik, Lill Andersen, Stefan Kraus. A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Developmental biology. vol 311. issue 1. 2007-12-03. PMID:17916349. |
furthermore, we show that a sustained canonical wnt activity in the lateral cortex gives rise to cells with hippocampal characteristics in the cortical plate at the expense of the cortical fate, and to cells with dentate gyrus characteristics in the hippocampus. |
2007-12-03 |
2023-08-12 |
Not clear |
| Amaya Miquelajauregui, Tom Van de Putte, Alexander Polyakov, Anjana Nityanandam, Sridhar Boppana, Eve Seuntjens, Anton Karabinos, Yujiro Higashi, Danny Huylebroeck, Victor Tarabyki. Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 31. 2007-09-21. PMID:17644613. |
sip1 is therefore essential to the development of the hippocampus and dentate gyrus, and is able to modulate wnt signaling in these regions. |
2007-09-21 |
2023-08-12 |
mouse |
| Guangnan Li, Samuel J Pleasur. Morphogenesis of the dentate gyrus: what we are learning from mouse mutants. Developmental neuroscience. vol 27. issue 2-4. 2005-08-25. PMID:16046842. |
for example the wnt pathway (steps 1, 2, 4) and the chemokine receptor cxcr4 (steps 3, 4) are involved in multiple developmental steps, while the neuronal differentiation gene neurod (step 6) and the integrin signaling pathway (step 5) are involved only in discrete stages of the dentate gyrus morphogenesis. |
2005-08-25 |
2023-08-12 |
mouse |
| H Roelin. Hippocampus formation: an intriguing collaboration. Current biology : CB. vol 10. issue 7. 2000-05-16. PMID:10753739. |
recent genetic studies have shown that the signalling factor wnt3a is required for formation of the hippocampus; the developmental consequences of wnt signalling in the hippocampus are mediated by multiple hmg-box transcription factors, with lef-1 being required just for formation of the dentate gyrus. |
2000-05-16 |
2023-08-12 |
Not clear |