| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maysam Fadaei-Kenarsary, Khadijeh Esmaeilpour, Mohammad Shabani, Vahid Sheiban. Maternal Substance Use and Early-Life Adversity: Inducing Drug Dependence in Offspring, Interactions, Mechanisms, and Treatments. Addiction & health. vol 16. issue 1. 2024-04-23. PMID:38651025. |
the brain's lateral paragigantocellularis (lpgi), nucleus accumbens (nac), caudate-putamen (cpu), prefrontal cortex (pfc), and hippocampus, can be affected by ms. dopamine receptor subtype genes, alcohol biomarker minor allele, and preproenkephalin mrna may be affected by alcohol or substance use disorders. |
2024-04-23 |
2024-04-26 |
Not clear |
| Matthew P Gunn, Gregory M Rose, Alexis E Whitton, Diego A Pizzagalli, David G Gilber. Smoking Progression and Nicotine-Enhanced Reward Sensitivity Predicted by Resting-State Functional Connectivity in Salience and Executive Control Networks. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2024-04-16. PMID:38624067. |
we hypothesized that high rsfc between brain areas with high densities of nicotinic receptors (insula, anterior cingulate cortex [acc], hippocampus, thalamus) and areas involved in reward-seeking (nucleus accumbens [nacc], prefrontal cortex [pfc]) would predict nicotine-enhanced reward sensitivity and smoking progression. |
2024-04-16 |
2024-04-18 |
Not clear |
| Lu Liu, Jie Wu, Changlin Zhang, Tong Cao, Yongli Lu, Zhi He, Zicheng L. Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice. Brain research. 2024-04-11. PMID:38604556. |
(2) the endoplasmic reticulum stress-related proteins in the lateral habenula (lhb) but not in the nucleus accumbens (nac), ventral pallidum (vp), basolateral amygdala (bla) and ca1 of hippocampus was upregulated by morphine withdrawal, upregulation of endoplasmic reticulum stress-related proteins in the lateral habenula induced by morphine withdrawal was inhibited by 4-pba. |
2024-04-11 |
2024-04-14 |
mouse |
| Shahrzad Nazari, Mitra-Sadat Sadat-Shirazi, Ali Shahbazi, Kamran Ghaffari, Nasim Vousoogh. The effect of morphine administration on GluN3B NMDA receptor subunit mRNA expression in rat brain. Acta neurobiologiae experimentalis. vol 84. issue 1. 2024-04-08. PMID:38587320. |
the mrna level of the glun3b subunit of the nmda receptor in the striatum, hippocampus, and nucleus accumbens (nac) was measured by real‑time pcr. |
2024-04-08 |
2024-04-10 |
rat |
| Tsun Hay Jason Ng, Mohammed H Sarikahya, Roger Hudson, Hanna J Szkudlarek, Enzo Pérez-Valenzuela, Taygun C Uzuneser, Emma Proud, Dana Gummerson, Miray Youssef, Madeline Machado, Kuralay Zhaksylyk, Marieka V DeVuono, Chaochao Chen, Ken K-C Yeung, Walter J Rushlow, Steven R Laviolett. Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-24. PMID:38521861. |
specifically, brain regions such as the medial prefrontal cortex (mpfc), the ventral tegmental area (vta), nucleus accumbens (nac) and hippocampus, are implicated in both nicotine dependence and pathological phenotypes linked to mood and anxiety disorders. |
2024-03-24 |
2024-03-26 |
rat |
| Kaili Du, Qianwen Shi, Xiuya Zhou, Lifei Zhang, Hongliang Su, Chao Zhang, Zhiwen Wei, Ting Liu, Li Wang, Xiaohui Wang, Bin Cong, Keming Yu. Melatonin attenuates fentanyl - induced behavioral sensitization and circadian rhythm disorders in mice. Physiology & behavior. 2024-03-16. PMID:38492912. |
the accompanying changes in the expression of brain and muscle arnt-like (bmal1), tyrosine hydroxylase (th), and monoamine oxidase a (mao-a) in relevant brain regions including the suprachiasmatic nucleus (scn), nucleus accumbens (nac), prefrontal cortex (pfc), and hippocampus (hip) were investigated by western blot assays to dissect the mechanism by which melatonin modulates fentanyl - induced behavioral sensitization and circadian rhythm disorders. |
2024-03-16 |
2024-03-19 |
mouse |
| Yingying Chen, Xiaodi Xia, Zheyi Zhou, Meng Yuan, Yadong Peng, Ying Liu, Jinxiang Tang, Yixiao F. Interleukin-6 is correlated with amygdala volume and depression severity in adolescents and young adults with first-episode major depressive disorder. Brain imaging and behavior. 2024-03-12. PMID:38467915. |
in this study, we aimed to investigate the potential correlations among cytokines, depression severity, and the volumes of the amygdala, hippocampus, and nucleus accumbens in han chinese adolescents and young adults with first-episode mdd. |
2024-03-12 |
2024-03-14 |
Not clear |
| Alicia C Wells, Shahrdad Lotfipou. Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits. Advances in drug and alcohol research. vol 3. 2024-02-23. PMID:38389806. |
due to the large percentage of women utilizing nicotine products during pregnancy in the united states and globally, this review seeks to centralize pre-clinical and clinical studies focused on the neurobehavioral and neurodevelopmental complications associated with prenatal nicotine exposure (pne) such as alterations to the hypothalamic-pituitary-adrenal (hpa) axis and brain regions such as the prefrontal cortex (pfc), ventral tegmental area (vta), nucleus accumbens (na), hippocampus, and caudate as well as changes to nachr and cholinergic receptor signaling, long-term drug seeking behavior following pne, and other related developmental disorders. |
2024-02-23 |
2024-02-25 |
Not clear |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
similar reversal effects of fluoxetine and vortioxetine were observed, including sert in the amygdala and net in the mpfc, whereas different reversal effects were observed for net in the hippocampus and vesicular monoamine transporters expression in the nucleus accumbens. |
2024-02-09 |
2024-02-12 |
mouse |
| Robin Nguyen, Sanghavy Sivakumaran, Evelyn K Lambe, Jun Chul Ki. Ventral hippocampal cholecystokinin interneurons gate contextual reward memory. iScience. vol 27. issue 2. 2024-02-02. PMID:38303709. |
here, we demonstrate that the encoding of context-reward memory requires a ventral hippocampus (vhpc) to nucleus accumbens (nac) circuit that is gated by cholecystokinin (cck) interneurons. |
2024-02-02 |
2024-02-04 |
Not clear |
| Ashley E Copenhaver, Tara A LeGate. Sex-specific mechanisms underlie long-term potentiation at hippocampus-nucleus accumbens synapses. bioRxiv : the preprint server for biology. 2024-01-31. PMID:38293132. |
the connection between the hippocampus (hipp) and nucleus accumbens (nac) is a crucial site where modulation of neuronal activity mediates reward-related behavior. |
2024-01-31 |
2024-02-02 |
mouse |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
the pathophysiology of depression is related to the reduced volume of the hippocampus and amygdala and hypertrophy of the nucleus accumbens. |
2024-01-11 |
2024-01-13 |
rat |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
the changes in d2, 5-ht1a and 5-ht2a receptor density in the nucleus accumbens and hippocampus were observed as a long-lasting effect. |
2024-01-11 |
2024-01-13 |
rat |
| Carolina Caban Rivera, Rachael Price, Ricardo P Fortuna, Chen Li, Chau Do, Justin Shinkle, Marco G Ghilotti, Xiangdang Shi, Lynn G Kirby, George M Smith, Ellen M Unterwal. The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076811. |
the ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. |
2023-12-11 |
2023-12-17 |
mouse |
| Carolina Caban Rivera, Rachael Price, Ricardo P Fortuna, Chen Li, Chau Do, Justin Shinkle, Marco G Ghilotti, Xiangdang Shi, Lynn G Kirby, George M Smith, Ellen M Unterwal. The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076811. |
mice underwent chemogenetic inhibition of either nucleus accumbens (na) neurons or the glutamatergic projection neurons from the ventral hippocampus (vhpc) to na using inhibitory designer receptors exclusively activated by designer drugs (idreadd). |
2023-12-11 |
2023-12-17 |
mouse |
| Madalyn Hafenbreidel, Surya Pandey, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Annika Tiller, Alice B Hall, Shayna Reed, Natasha Mayorga, Li Lin, Susan Khan, Michael D Cameron, Gavin Rumbaugh, Courtney A Mille. Basolateral Amygdala Corticotropin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory in Males. Neurobiology of learning and memory. 2023-11-23. PMID:37995804. |
the effect is highly selective, as nmii inhibition has no effect in other relevant brain regions (e.g., dorsal hippocampus [dphc], nucleus accumbens [nac]), nor does it interfere with associations for other aversive or appetitive stimuli, including cocaine (coc). |
2023-11-23 |
2023-11-29 |
mouse |
| Mauricio Quezada, Carolina Ponce, Pablo Berríos-Cárcamo, Daniela Santapau, Javiera Gallardo, Cristian De Gregorio, María Elena Quintanilla, Paola Morales, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Paula Andrés-Herrera, Lucia Hipólito, Fernando Ezque. Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence. CNS neuroscience & therapeutics. 2023-11-06. PMID:37927136. |
the morphine-induced increases in neuroinflammation, brain oxidative stress, and alteration of glutamate levels in the hippocampus and nucleus accumbens have been associated with morphine dependence and a higher severity of withdrawal symptoms. |
2023-11-06 |
2023-11-08 |
human |
| Woonyen Wong, Youssef Sar. Effects of Chronic Hydrocodone Exposure and Ceftriaxone on the Expression of Astrocytic Glutamate Transporters in Mesocorticolimbic Brain Regions of C57/BL Mice. Toxics. vol 11. issue 10. 2023-10-27. PMID:37888720. |
our laboratory has shown that exposure to lower doses of hydrocodone reduced the expression of xct in the nucleus accumbens (nac) and the hippocampus. |
2023-10-27 |
2023-11-08 |
mouse |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |