| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A I Glen, C M Yates, J Simpson, J E Christie, A Shering, L J Whalley, E H Jelline. Choline uptake in patients with Alzheimer pre-senile dementia. Psychological medicine. vol 11. issue 3. 1981-10-25. PMID:7267882. |
choline uptake in patients with alzheimer pre-senile dementia. |
1981-10-25 |
2023-08-12 |
Not clear |
| K Kosaka, R Iizuka, Y Mizutani, T Kondo, T Nagats. Striatonigral degeneration combined with Alzheimer's disease. Acta neuropathologica. vol 54. issue 3. 1981-09-25. PMID:6114611. |
an autopsy case with clinical features of progressive parkinsonism and dementia of presenile occurrence was characterized by the following neuropathological findings: (1) severe degeneration in the striatonigral system and (2) widespread occurrence of numerous senile plaques and alzheimer's neurofibrillary tangles in the cerebral cortex. |
1981-09-25 |
2023-08-12 |
Not clear |
| P Davies, S Feisulli. Postmortem stability of alpha-bungarotoxin binding sites in mouse and human brain. Brain research. vol 216. issue 2. 1981-09-25. PMID:7248786. |
no correlation between the number of binding sites and the delay period between death and autopsy was found in studies of frontal cortex or mid-temporal gyrus from normal humans or cases of dementia of the alzheimer type. |
1981-09-25 |
2023-08-12 |
mouse |
| E K Perry, B E Tomlinson, G Blessed, R H Perry, A J Cross, T T Cro. Noradrenergic and cholinergic systems in senile dementia of Alzheimer type. Lancet (London, England). vol 2. issue 8238. 1981-08-27. PMID:6113507. |
noradrenergic and cholinergic systems in senile dementia of alzheimer type. |
1981-08-27 |
2023-08-12 |
Not clear |
| M J Ball, K Nuttal. Topography of neurofibrillary tangles and granulovacuoles in hippocampi of patients with Down's syndrome: quantitative comparison with normal ageing and Alzheimer's disease. Neuropathology and applied neurobiology. vol 7. issue 1. 1981-07-20. PMID:6453301. |
these striking regional predispositions suggest that a common neurotransmitter deficit may underlie the local selectivity of such lesions in down's syndrome brains; and the predilections' marked similarities to ranking orders, already noted both in normal aged subjects and especially in senile dements of the alzheimer type, enhance the importance of the down's syndrome neuraxis as a key to the puzzle of alzheimer's dementia. |
1981-07-20 |
2023-08-12 |
human |
| A E George, M J de Leon, S H Ferris, I I Krichef. Parenchymal CT correlates of senile dementia (Alzheimer disease): loss of gray-white matter discriminability. AJNR. American journal of neuroradiology. vol 2. issue 3. 1981-07-09. PMID:6786056. |
parenchymal ct correlates of senile dementia (alzheimer disease): loss of gray-white matter discriminability. |
1981-07-09 |
2023-08-12 |
Not clear |
| B M Hubbard, J M Anderso. A quantitative study of cerebral atrophy in old age and senile dementia. Journal of the neurological sciences. vol 50. issue 1. 1981-07-09. PMID:7229656. |
patients with alzheimer type dementia aged less than 80 years mainly showed pathological cerebral atrophy with global loss of cerebral tissue (p less than 0.001) whereas over 80 years of age they generally showed selective atrophy of temporal cortex (p less than 0.005). |
1981-07-09 |
2023-08-12 |
Not clear |
| B E Tomlinson, D Irving, G Blesse. Cell loss in the locus coeruleus in senile dementia of Alzheimer type. Journal of the neurological sciences. vol 49. issue 3. 1981-06-23. PMID:7217992. |
cell loss in the locus coeruleus in senile dementia of alzheimer type. |
1981-06-23 |
2023-08-12 |
Not clear |
| B E Tomlinson, D Irving, G Blesse. Cell loss in the locus coeruleus in senile dementia of Alzheimer type. Journal of the neurological sciences. vol 49. issue 3. 1981-06-23. PMID:7217992. |
sample counts of the pigmented cells of the locus coeruleus (lc) were performed in 10 middle-aged and 15 old people considered to be intellectually well preserved and in 15 cases of senile dementia of alzheimer type (sdat). |
1981-06-23 |
2023-08-12 |
Not clear |
| M A Bell, M J Bal. Morphometric comparison of hippocampal microvasculature in ageing and demented people: diameters and densities. Acta neuropathologica. vol 53. issue 4. 1981-06-13. PMID:7223373. |
the diameters and densities of capillaries and arterioles in the hippocampal cortex of normal subjects and patients with alzheimer's dementia were measured in thick celloidin sections stained for alkaline phosphatase. |
1981-06-13 |
2023-08-12 |
human |
| R Schechter, S H Yen, R D Terr. Fibrous Astrocytes in senile dementia of the Alzheimer type. Journal of neuropathology and experimental neurology. vol 40. issue 2. 1981-04-24. PMID:7007585. |
here the mean count of fibrous astrocytes in senile dementia of the alzheimer type was more than four times that of the normal aged cortex. |
1981-04-24 |
2023-08-12 |
Not clear |
| M N Rossor, P C Emson, C Q Mountjoy, M Roth, L L Iverse. Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type. Neuroscience letters. vol 20. issue 3. 1981-02-24. PMID:6108540. |
reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of alzheimer type. |
1981-02-24 |
2023-08-12 |
Not clear |
| D Shore, M R Wills, J Savory, R J Wyat. Serum parathyroid hormone concentrations in senile dementia (Alzheimer's disease). Journal of gerontology. vol 35. issue 5. 1981-01-29. PMID:7430560. |
the accumulation of aluminum in the cerebral cortex has been implicated as a factor in the pathogenesis of alzheimer type senile dementia (sd) and in the dialysis dementia found in patients with chronic renal failure on long-term intermittent hemodialysis treatment. |
1981-01-29 |
2023-08-12 |
Not clear |
| P Davies, R Katzman, R D Terr. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa. Nature. vol 288. issue 5788. 1981-01-26. PMID:6107862. |
both alzheimer's disease and senile dementia of the alzheimer type (ad/sdat) are progressive dementias characterized neuropathologically by the presence in the cerebral cortex of numerous neurofibrillary tangles and neuritic plaques. |
1981-01-26 |
2023-08-12 |
Not clear |
| V Argentiero, B Tavolat. Dopamine (DA) and serotonin metabolic levels in the cerebrospinal fluid (CSF) in Alzheimer's presenile dementia under basic conditions and after stimulation with cerebral cortex phospholipids (BC-PL). Journal of neurology. vol 224. issue 1. 1980-11-24. PMID:6157799. |
dopamine (da) and serotonin metabolic levels in the cerebrospinal fluid (csf) in alzheimer's presenile dementia under basic conditions and after stimulation with cerebral cortex phospholipids (bc-pl). |
1980-11-24 |
2023-08-12 |
Not clear |
| M J Ball, K Nuttal. Neurofibrillary tangles, granulovacuolar degeneration, and neuron loss in Down Syndrome: quantitative comparison with Alzheimer dementia. Annals of neurology. vol 7. issue 5. 1980-09-28. PMID:6446875. |
by contrast, the number of alzheimer neurofibrillary tangles and loss of pyramidal neurons from the hippocampus exceeded levels found in considerably older subjects and fell into the same range of severity as was noted in 8 patients with alzheimer dementia. |
1980-09-28 |
2023-08-12 |
human |
| P E Duffy, M Rapport, L Gra. Glial fibrillary acidic protein and Alzheimer-type senile dementia. Neurology. vol 30. issue 7 Pt 1. 1980-09-26. PMID:7190246. |
glial fibrillary acidic protein (gfap), a protein that is associated with 9-nm filaments of astrocytes, was observed to be increased in the astrocytes surrounding senile plaques in patients with alzheimer dementia and in aged subjects without dementia. |
1980-09-26 |
2023-08-12 |
human |
| D M Mann, J Lincoln, P O Yates, J E Stamp, S Tope. Changes in the monoamine containing neurones of the human CNS in senile dementia. The British journal of psychiatry : the journal of mental science. vol 136. 1980-09-23. PMID:6155966. |
in thirteen cases of senile dementia of the alzheimer type severe loss of nerve cells from the locus caeruleus was frequently seen together with reductions in nucleolar volume and cytoplasmic rna in surviving cells, averaging 14 and 21 per cent respectively. |
1980-09-23 |
2023-08-12 |
human |
| D M Mann, J Lincoln, P O Yates, J E Stamp, S Tope. Changes in the monoamine containing neurones of the human CNS in senile dementia. The British journal of psychiatry : the journal of mental science. vol 136. 1980-09-23. PMID:6155966. |
these findings provide evidence of a primary degeneration of the noradrenergic system in alzheimer type dementia. |
1980-09-23 |
2023-08-12 |
human |
| M A Naeser, C Gebhardt, H L Levin. Decreased computerized tomography numbers in patients with presenile dementia. Detection in patients with otherwise normal scans. Archives of neurology. vol 37. issue 7. 1980-08-28. PMID:6446279. |
patients in their 50s who show clinical signs of dementia (possible alzheimer's disease) often have ocmputerized tomographic (ct) scans that appear normal. |
1980-08-28 |
2023-08-12 |
Not clear |