| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anurag Kumar Singh, Snigdha Singh, Tarun Minocha, Sanjeev Kumar Yadav, Reema Narayan, Usha Yogendra Nayak, Santosh Kumar Singh, Rajendra Awasth. Nanoscale advances. vol 6. issue 9. 2024-05-02. PMID:38694466. |
neuronal loss in alzheimer's disease has been reported to display features of apoptosis, pyroptosis (programmed necrosis), or necroptosis. |
2024-05-02 |
2024-05-04 |
Not clear |
| Anowarul Islam, Zeeshan Shaukat, Rashid Hussain, Michael G Ricos, Leanne M Dibbens, Stephen L Gregor. Aneuploidy is Linked to Neurological Phenotypes Through Oxidative Stress. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-05-01. PMID:38693434. |
a growing body of research from numerous laboratories suggests that many neurodegenerative disorders, especially alzheimer's disease and frontotemporal dementia, are characterised by neuronal aneuploidy and the ensuing apoptosis, which may contribute to neuronal loss. |
2024-05-01 |
2024-05-04 |
drosophila_melanogaster |
| Saba Foroughi, Kahin Shahanipour, Ramesh Monajemi, Ali Mohammad Ahad. Investigating the effects of Thymus vulgaris essential oil, Allium cepa extract, and their active compounds (thymol and quercetin) on expression profile of genes related to Alzheimer's disease in PC12 model cell. Brain research. 2024-04-30. PMID:38688382. |
in addition, quercetin was able to reduce the rate of apoptosis in alzheimer's cells (4.73 %) which was greater than the effects of other compounds. |
2024-04-30 |
2024-05-03 |
Not clear |
| b' Dianxia Xing, Wenjin Zhang, Wei Cui, Xiuya Yao, Yaping Xiao, Lihua Chen, Shiyun Yuan, Yanyan Duan, Weihua Yu, Pengfei Pan, Yang L\\xc3\\xb. SIRT4 promotes neuronal apoptosis in models of Alzheimer\'s disease via the STAT2-SIRT4-mTOR pathway. American journal of physiology. Cell physiology. 2024-04-08. PMID:38586875.' |
sirt4 promotes neuronal apoptosis in models of alzheimer's disease via the stat2-sirt4-mtor pathway. |
2024-04-08 |
2024-04-10 |
mouse |
| Mubeen A Ansari, Aishah Al-Jarallah, Muddanna S Rao, Ahmed Babiker, Khaled Bensalama. Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer's disease. Brain research. 2024-03-29. PMID:38552936. |
upregulation of nadph-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: development of sporadic alzheimer's disease. |
2024-03-29 |
2024-04-01 |
rat |
| Bidemi Emmanuel Ekundayo, Tajudeen Olabisi Obafemi, Olusola Bolaji Adewale, Blessing Ariyo Obafemi, Babatunji Emmanuel Oyinloye, Stella Kemilola Ekunday. Oxidative Stress, Endoplasmic Reticulum Stress and Apoptosis in the Pathology of Alzheimer's Disease. Cell biochemistry and biophysics. 2024-03-13. PMID:38472715. |
oxidative stress, endoplasmic reticulum stress and apoptosis in the pathology of alzheimer's disease. |
2024-03-13 |
2024-03-15 |
Not clear |
| Jichun Liu, Mingyuan Chi, Lianxin Li, Yuewen Zhang, Meng Xi. Erythrocyte membrane coated with nitrogen-doped quantum dots and polydopamine composite nano-system combined with photothermal treatment of Alzheimer's disease. Journal of colloid and interface science. vol 663. 2024-03-06. PMID:38447400. |
mitochondrial dysfunction and metal ion imbalance are recognized as pathological hallmarks of alzheimer's disease (ad), leading to deposition of β-amyloid (aβ) thereby and inducing neurotoxicity, activating apoptosis, eliciting oxidative stress, and ultimately leading to cognitive impairment. |
2024-03-06 |
2024-03-09 |
Not clear |
| Bizhan Helli, Seyedeh Parisa Navabi, Seyed Ahmad Hosseini, Ali Sabahi, Layasadat Khorsandi, Nasrin Amirrajab, Masoud Mahdavinia, Sohrab Rahmani, Mohammad Amin Dehghan. The Protective Effects of Syringic Acid on Bisphenol A-Induced Neurotoxicity Possibly Through AMPK/PGC-1α/Fndc5 and CREB/BDNF Signaling Pathways. Molecular neurobiology. 2024-03-02. PMID:38430353. |
therefore, in this study, we aimed to investigate the effects of sa on oxidative stress, apoptosis, memory and locomotor disorders, and mitochondrial function, and to identify the mechanisms related to alzheimer's disease (ad) in the brain of rats receiving high doses of bpa. |
2024-03-02 |
2024-03-04 |
rat |
| Mingyang Qiu, Jianqing Zhang, Wenlong Wei, Yan Zhang, Mengmeng Li, Yuxin Bai, Hanze Wang, Qian Meng, De-An Gu. Integrated UPLC/Q-TOF-MS/MS Analysis and Network Pharmacology to Reveal the Neuroprotective Mechanisms and Potential Pharmacological Ingredients of Aurantii Fructus Immaturus and Aurantii Fructus. Pharmaceuticals (Basel, Switzerland). vol 17. issue 2. 2024-02-24. PMID:38399454. |
these activities are associated with the regulatory effects of related components on 146 important signaling pathways, derived from the kegg (kegg: kyoto encyclopedia of genes and genomes), such as neurodegeneration (hsa05022), the alzheimer's disease pathway (hsa05010), the nf-kappa b signaling pathway (hsa04064), the hypoxia-inducible factor (hif)-1 signaling pathway (hsa04066), apoptosis (hsa04210), the epidermal growth factor receptor (egfr) tyrosine kinase inhibitor resistance signaling pathway (hsa01521), and others, by targeting 108 proteins, including xanthine dehydrogenase (xdh), glutamate ionotropic receptor nmda type subunit 2b (grin2b), and glucose-6-phosphate dehydrogenase (g6pd), among others. |
2024-02-24 |
2024-02-26 |
human |
| D-Y Liu, L Zhan. Retraction Note: MicroRNA-132 promotes neurons cell apoptosis and activates Tau phosphorylation by targeting GTDC-1 in Alzheimer's disease. European review for medical and pharmacological sciences. vol 28. issue 3. 2024-02-20. PMID:38375693. |
retraction note: microrna-132 promotes neurons cell apoptosis and activates tau phosphorylation by targeting gtdc-1 in alzheimer's disease. |
2024-02-20 |
2024-02-22 |
Not clear |
| D-Y Liu, L Zhan. Retraction Note: MicroRNA-132 promotes neurons cell apoptosis and activates Tau phosphorylation by targeting GTDC-1 in Alzheimer's disease. European review for medical and pharmacological sciences. vol 28. issue 3. 2024-02-20. PMID:38375693. |
the article "microrna-132 promotes neurons cell apoptosis and activates tau phosphorylation by targeting gtdc-1 in alzheimer's disease", by d.-y. |
2024-02-20 |
2024-02-22 |
Not clear |
| b' Murat \\xc3\\x87ak\\xc4\\xb1r, Hikmet Sa\\xc3\\xa7mac\\xc4\\xb. The relationship of salusins with Parkinson\'s Disease, Alzheimer\'s Disease, and acute ischemic stroke: A preliminary study. Neuroscience letters. 2024-02-13. PMID:38350537.' |
neuroinflammation, oxidative stress, and apoptosis play important roles in the pathophysiology of alzheimer's disease (ad), parkinson's disease (pd), and acute ischemic stroke (ais). |
2024-02-13 |
2024-02-16 |
Not clear |
| Sweta Kamboj, Prerna Sharma, Rohit Kamboj, Shikha Kamboj, Hari Om, Girija, Kumar Guarve, Rohit Dutt, Inderjeet Verma, Kamal Dua, Nidhi Ran. Exploring the Therapeutic Potential of Phytoconstituents for Addressing Neurodegenerative Disorders. Central nervous system agents in medicinal chemistry. 2024-01-24. PMID:38265386. |
the major examples of neurodegenerative disorders are alzheimer's and parkinson's disease, in which apoptosis and necrosis are the two major death pathways for neurons. |
2024-01-24 |
2024-01-26 |
Not clear |
| Wei Ma, Kui Lu, Hua-Min Liang, Jin-Yuan Zhan. Synapsin 1 Ameliorates Cognitive Impairment and Neuroinflammation in Rats with Alzheimer's Disease: An Experimental and Bioinformatics Study. Current Alzheimer research. 2024-01-12. PMID:38213171. |
alzheimer's disease (ad) is a persistent neuropathological injury that manifests via neuronal/synaptic death, age spot development, tau hyperphosphorylation, neuroinflammation, and apoptosis. |
2024-01-12 |
2024-01-14 |
rat |
| Thien Hoang Minh Cao, Anh Phuc Hoang Le, Tai Tien Tran, Vy Kim Huynh, Bao Hoai Pham, Thao Mai Le, Quang Lam Nguyen, Thang Cong Tran, Trang Mai Tong, The Ha Ngoc Than, Tran Tran To Nguyen, Huong Thi Thanh H. Plasma cell-free RNA profiling of Vietnamese Alzheimer's patients reveals a linkage with chronic inflammation and apoptosis: a pilot study. Frontiers in molecular neuroscience. vol 16. 2024-01-05. PMID:38178908. |
plasma cell-free rna profiling of vietnamese alzheimer's patients reveals a linkage with chronic inflammation and apoptosis: a pilot study. |
2024-01-05 |
2024-01-07 |
Not clear |
| Lihua Wang, Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li, Zhaohua Wang, Muhammad Ali, Chengran Yang, Menghan Liu, William Brock, Marta Marquié, Mercè Boada, Ignacio Alvarez, Miquel Aguilar, Pau Pastor, Agustín Ruiz, Raquel Puerta, Adelina Orellana, Jarod Rutledge, Hamilton Oh, Michael D Greicius, Yann Le Guen, Richard J Perrin, Tony Wyss-Coray, Angela Jefferson, Timothy J Hohman, Neill Graff-Radford, Hiroshi Mori, Alison Goate, Johannes Levin, Yun Ju Sung, Carlos Cruchag. Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. Molecular neurodegeneration. vol 19. issue 1. 2024-01-03. PMID:38172904. |
triggering receptor expressed on myeloid cells 2 (trem2) plays a critical role in microglial activation, survival, and apoptosis, as well as in alzheimer's disease (ad) pathogenesis. |
2024-01-03 |
2024-01-06 |
Not clear |
| Erdong Zhang, Fengqiu Da. Diagnostic Model for Alzheimer's Disease Based on PANoptosis-Related Genes. Journal of Alzheimer's disease : JAD. 2023-12-31. PMID:38160361. |
the pathophysiology of alzheimer's disease (ad) involves the interplay of three different processes: pyroptosis, apoptosis, and necroptosis. |
2023-12-31 |
2024-01-05 |
Not clear |
| Hangjia Bai, Yanliang Wu, Haini Li, Yining Zhu, Ruijie Che, Fenghe Wang, Chaofeng Zhan. Cerebral neurotoxicity of amino-modified polystyrene nanoplastics in mice and the protective effects of functional food Camellia pollen. The Science of the total environment. 2023-12-25. PMID:38145676. |
this study established that camellia pollen protects the brain against aps-nps-mediated blood-brain barrier damage and alleviates neuronal apoptosis and alzheimer's disease-like neurotoxicity. |
2023-12-25 |
2023-12-28 |
mouse |
| Saily Sosa, Giosmany Bringas, Nelky Urrutia, Ana Ivis Peñalver, Danay López, Evelio González, Ana Fernández, Zenaida Milagros Hernández, Ariel Viña, Yamile Peña, Juan Felipe Batista, Carmen Valenzuela, Kalet León, Tania Crombet, Teresita Rodríguez, Leslie Pére. NeuroEPO plus (NeuralCIM Alzheimer's research & therapy. vol 15. issue 1. 2023-12-14. PMID:38093366. |
neuroepo plus prevents oxidative damage, neuroinflammation, apoptosis and cognitive deficit in an alzheimer's disease (ad) models. |
2023-12-14 |
2023-12-17 |
human |
| Bernadeta A Pietrzak-Wawrzyńska, Agnieszka Wnuk, Karolina Przepiórska-Drońska, Andrzej Łach, Małgorzata Kajt. Posttreatment with PaPE-1 Protects from Aβ-Induced Neurodegeneration Through Inhibiting the Expression of Alzheimer's Disease-Related Genes and Apoptosis Process That Involves Enhanced DNA Methylation of Specific Genes. Molecular neurobiology. 2023-12-08. PMID:38064105. |
posttreatment with pape-1 protects from aβ-induced neurodegeneration through inhibiting the expression of alzheimer's disease-related genes and apoptosis process that involves enhanced dna methylation of specific genes. |
2023-12-08 |
2023-12-17 |
mouse |