| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ignazio S Piras, Jonida Krate, Isabelle Schrauwen, Jason J Corneveaux, Geidy E Serrano, Lucia Sue, Thomas G Beach, Matthew J Huentelma. Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway. Hippocampus. vol 27. issue 7. 2018-04-18. PMID:28380666. |
the rs17070145-t variant of the wwc1 gene, coding for the kibra protein, has been associated with both increased episodic memory performance and lowered risk for late onset alzheimer's disease, although the mechanism behind this protective effect has not been completely elucidated. |
2018-04-18 |
2023-08-13 |
human |
| Ignazio S Piras, Jonida Krate, Isabelle Schrauwen, Jason J Corneveaux, Geidy E Serrano, Lucia Sue, Thomas G Beach, Matthew J Huentelma. Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway. Hippocampus. vol 27. issue 7. 2018-04-18. PMID:28380666. |
in conclusion, our results suggest that the effect of the wwc1 rs17070145 polymorphism on memory performance and alzheimer's disease might be due to a differential regulation of the mapk signaling, a key pathway involved in memory and learning processes. |
2018-04-18 |
2023-08-13 |
human |
| Matteo De Marco, Annamaria Vallelunga, Francesca Meneghello, Susheel Varma, Alejandro F Frangi, Annalena Venner. ApoE ε4 Allele Related Alterations in Hippocampal Connectivity in Early Alzheimer's Disease Support Memory Performance. Current Alzheimer research. vol 14. issue 7. 2018-04-10. PMID:28176662. |
apoe ε4 allele related alterations in hippocampal connectivity in early alzheimer's disease support memory performance. |
2018-04-10 |
2023-08-13 |
Not clear |
| Jorge Valero, Liliana Bernardino, Filipa Lourenço Cardoso, Ana Paula Silva, Carlos Fontes-Ribeiro, António Francisco Ambrósio, João Oliveira Malv. Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue s1. 2018-04-06. PMID:28671124. |
in the present manuscript, we highlight the functional interplay between neuroinflammation, dynamics of the neurogenic niche, and spatial memory performance in healthy and age-related pathological processes, including progression of alzheimer's disease. |
2018-04-06 |
2023-08-13 |
Not clear |
| Feng Lin, Ping Ren, Raymond Y Lo, Benjamin P Chapman, Alanna Jacobs, Timothy M Baran, Anton P Porsteinsson, John J Fox. Insula and Inferior Frontal Gyrus' Activities Protect Memory Performance Against Alzheimer's Disease Pathology in Old Age. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27716674. |
insula and inferior frontal gyrus' activities protect memory performance against alzheimer's disease pathology in old age. |
2018-02-22 |
2023-08-13 |
human |
| Monika Mandecka, Magdalena Budziszewska, Anna Barczak, Beata Pepłońska, Małgorzata Chodakowska-Żebrowska, Anna Filipek-Gliszczyńska, Marta Nesteruk, Maria Styczyńska, Maria Barcikowska, Tomasz Gabryelewic. Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 1. 2018-01-29. PMID:27472875. |
the aim of this study was to estimate the prevalence of ad csf biomarkers in those individuals with a subjective cognitive decline (scd), a mild cognitive impairment (mci), and alzheimer's dementia (ad-d), together with the relationships between the biomarkers, an apoe ɛ4 presence, and a verbal episodic memory performance. |
2018-01-29 |
2023-08-13 |
Not clear |
| Véréna Landel, Cédric Annweiler, Pascal Millet, Maria Morello, François Féro. Vitamin D, Cognition and Alzheimer's Disease: The Therapeutic Benefit is in the D-Tails. Journal of Alzheimer's disease : JAD. vol 53. issue 2. 2018-01-25. PMID:27176073. |
in parallel, animal studies show that supplementation with vitamin d is protective against biological processes associated with alzheimer's disease (ad) and enhances learning and memory performance in various animal models of aging and ad. |
2018-01-25 |
2023-08-13 |
human |
| Dongsheng Zhou, Huaxia Liu, Chenli Li, Fangyan Wang, Yaosheng Shi, Lingjiang Liu, Xin Zhao, Aiming Liu, Junfang Zhang, Chuang Wang, Zhongming Che. Atorvastatin ameliorates cognitive impairment, Aβ1-42 production and Tau hyperphosphorylation in APP/PS1 transgenic mice. Metabolic brain disease. vol 31. issue 3. 2018-01-12. PMID:26883430. |
atorvastatin, a hmg-coa reductase inhibitor, has been proven to improve learning and memory performance, reduce aβ and phosphorylated tau levels in mouse model of alzheimer's disease (ad). |
2018-01-12 |
2023-08-13 |
mouse |
| T C Foster, C Kyritsopoulos, A Kuma. Central role for NMDA receptors in redox mediated impairment of synaptic function during aging and Alzheimer's disease. Behavioural brain research. vol 322. issue Pt B. 2017-11-30. PMID:27180169. |
impaired executive function and memory performance are observed in normal aging and yet can be an early sign of a progressive cognitive impairment of alzheimer's disease (ad), the most common form of dementia. |
2017-11-30 |
2023-08-13 |
human |
| Stephan Müller, Christian Mychajliw, Carolin Reichert, Tobias Melcher, Thomas Leyh. Autobiographical Memory Performance in Alzheimer's Disease Depends on Retrieval Frequency. Journal of Alzheimer's disease : JAD. vol 52. issue 4. 2017-10-25. PMID:27104895. |
autobiographical memory performance in alzheimer's disease depends on retrieval frequency. |
2017-10-25 |
2023-08-13 |
Not clear |
| Simon J Schreiner, Thomas Kirchner, Michael Wyss, Jiri M G Van Bergen, Frances C Quevenco, Stefanie C Steininger, Erica Y Griffith, Irene Meier, Lars Michels, Anton F Gietl, Sandra E Leh, Adam M Brickman, Christoph Hock, Roger M Nitsch, Klaas P Pruessmann, Anke Henning, Paul G Unschul. Low episodic memory performance in cognitively normal elderly subjects is associated with increased posterior cingulate gray matter N-acetylaspartate: a Neurobiology of aging. vol 48. 2017-10-12. PMID:27718422. |
low episodic memory performance in cognitively normal elderly subjects is associated with increased posterior cingulate gray matter n-acetylaspartate: a low episodic memory performance characterizes elderly subjects at increased risk for alzheimer's disease (ad) and may reflect neuronal dysfunction within the posterior cingulate cortex and precuneus (pcp) region. |
2017-10-12 |
2023-08-13 |
human |
| Mark Mapstone, Feng Lin, Mike A Nalls, Amrita K Cheema, Andrew B Singleton, Massimo S Fiandaca, Howard J Federof. What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease. Neurobiology of aging. vol 51. 2017-09-28. PMID:27939698. |
here, we studied 224 older adults, some with superior memory performance (n = 41), some with normal memory performance (n = 109), and some with mild cognitive impairment or alzheimer's disease (ad; n = 74) to understand metabolomic differences which might inform future interventions to promote cognitive health. |
2017-09-28 |
2023-08-13 |
Not clear |
| Veronica Burnham, Christopher Sundby, Abigail Laman-Maharg, Janice Thornto. Luteinizing hormone acts at the hippocampus to dampen spatial memory. Hormones and behavior. vol 89. 2017-09-04. PMID:27847314. |
luteinizing hormone (lh) rises dramatically during and after menopause, and has been correlated with an increased incidence of alzheimer's disease and decreased memory performance in humans and animal models. |
2017-09-04 |
2023-08-13 |
human |
| Sandrine Kalenzaga, Virginie Lamidey, Anne-Marie Ergis, David Clarys, Pascale Piolin. The positivity bias in aging: Motivation or degradation? Emotion (Washington, D.C.). vol 16. issue 5. 2017-07-24. PMID:26950366. |
we compared immediate (i.e., immediate recall) versus delayed (i.e., delayed recall and recognition) emotional memory performance in 38 young adults, 39 old adults, 37 very old adults, and 41 alzheimer's disease patients. |
2017-07-24 |
2023-08-13 |
human |
| Jasmeet P Hayes, Mark W Logue, Naomi Sadeh, Jeffrey M Spielberg, Mieke Verfaellie, Scott M Hayes, Andrew Reagan, David H Salat, Erika J Wolf, Regina E McGlinchey, William P Milberg, Annjanette Stone, Steven A Schichman, Mark W Mille. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28077398. |
a moderated mediation analysis showed that mild traumatic brain injury and high genetic risk indirectly influenced episodic memory performance through cortical thickness, suggesting that cortical thinning in alzheimer's disease-vulnerable brain regions is a mechanism for reduced memory performance. |
2017-05-29 |
2023-08-13 |
human |
| Jasmeet P Hayes, Mark W Logue, Naomi Sadeh, Jeffrey M Spielberg, Mieke Verfaellie, Scott M Hayes, Andrew Reagan, David H Salat, Erika J Wolf, Regina E McGlinchey, William P Milberg, Annjanette Stone, Steven A Schichman, Mark W Mille. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28077398. |
these results provide evidence that mild traumatic brain injury is associated with greater neurodegeneration and reduced memory performance in individuals at genetic risk for alzheimer's disease, with the caveat that the order of causal effects cannot be inferred from cross-sectional studies. |
2017-05-29 |
2023-08-13 |
human |
| Lior Greenbaum, Ramit Ravona-Springer, Irit Lubitz, James Schmeidler, Itzik Cooper, Mary Sano, Jeremy M Silverman, Anthony Heymann, Michal Schnaider Beer. Potential contribution of the Alzheimer's disease risk locus BIN1 to episodic memory performance in cognitively normal Type 2 diabetes elderly. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 4. 2017-05-03. PMID:26947052. |
potential contribution of the alzheimer's disease risk locus bin1 to episodic memory performance in cognitively normal type 2 diabetes elderly. |
2017-05-03 |
2023-08-13 |
Not clear |
| Zahra Mokhtari, Tourandokht Baluchnejadmojarad, Farnaz Nikbakht, Monireh Mansouri, Mehrdad Roghan. Riluzole ameliorates learning and memory deficits in Aβ25-35-induced rat model of Alzheimer's disease and is independent of cholinoceptor activation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 87. 2017-02-21. PMID:28049095. |
riluzole is a glutamate modulator which has shown to improve memory performance in aged rats and may be of benefit in alzheimer's disease. |
2017-02-21 |
2023-08-13 |
rat |
| Sahreh Shabani, Alireza Sarkaki, Seyyed Ali Mard, Akram Ahangarpour, Layasadat Khorsandi, Yaghoob Farboo. Central and peripheral administrations of levothyroxine improved memory performance and amplified brain electrical activity in the rat model of Alzheimer's disease. Neuropeptides. vol 59. 2017-02-14. PMID:27640349. |
central and peripheral administrations of levothyroxine improved memory performance and amplified brain electrical activity in the rat model of alzheimer's disease. |
2017-02-14 |
2023-08-13 |
rat |
| Chris M Foster, Donna Rose Addis, Jaclyn H Ford, Daniel I Kaufer, James R Burke, Jeffrey N Browndyke, Kathleen A Welsh-Bohmer, Kelly S Giovanell. Prefrontal contributions to relational encoding in amnestic mild cognitive impairment. NeuroImage. Clinical. vol 11. 2016-12-21. PMID:26937384. |
while there is some functional overlap in regions recruited by generation demands between the groups, the recruitment of frontal regions in the amci participants coincides with worse memory performance, likely representing a form of neural inefficiency associated with alzheimer's disease. |
2016-12-21 |
2023-08-13 |
human |