All Relations between Alzheimer Disease and microglial cell

Reference Sentence Publish Date Extraction Date Species
Oliver Cooper, Penny Hallett, Ole Isacso. The role of upstream lipid and metabolic systems in Alzheimer's disease, Parkinson's disease and dementias. The FEBS journal vol issue 2022 36165619 using microglia as an example, we review data that suggests increased lipid concentrations cause dysfunctional inflammatory responses to immune challenges, leading to alzheimer's disease, parkinson's disease and dementia. 2022-09-27 2022-09-29 Not clear
Marie-Kim St-Pierre, Mica\\xc3\\xabl Carrier, Fernando Gonz\\xc3\\xa1lez Ib\\xc3\\xa1\\xc3\\xb1ez, Eva \\xc5\\xa0imon\\xc4\\x8di\\xc4\\x8dov\\xc3\\xa1, Marie-Jos\\xc3\\xa9e Wallman, Luc Valli\\xc3\\xa8res, Martin Parent, Marie-\\xc3\\x88ve Trembla. Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer's disease pathology and in human post-mortem brain samples. Journal of neuroinflammation vol 19 issue 1 2022 36167544 ultrastructural characterization of dark microglia during aging in a mouse model of alzheimer's disease pathology and in human post-mortem brain samples. 2022-09-27 2022-09-29 Not clear
Marie-Kim St-Pierre, Mica\\xc3\\xabl Carrier, Fernando Gonz\\xc3\\xa1lez Ib\\xc3\\xa1\\xc3\\xb1ez, Eva \\xc5\\xa0imon\\xc4\\x8di\\xc4\\x8dov\\xc3\\xa1, Marie-Jos\\xc3\\xa9e Wallman, Luc Valli\\xc3\\xa8res, Martin Parent, Marie-\\xc3\\x88ve Trembla. Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer's disease pathology and in human post-mortem brain samples. Journal of neuroinflammation vol 19 issue 1 2022 36167544 a diverse heterogeneity of microglial cells was previously described in alzheimer's disease (ad) pathology, including dark microglia, a state characterized by ultrastructural markers of cellular stress. 2022-09-27 2022-09-29 Not clear
Wenliang Gao, Wei Kong, Shuaiqun Wang, Gen Wen, Yaling Y. Biomarker Genes Discovery of Alzheimer's Disease by Multi-Omics-Based Gene Regulatory Network Construction of Microglia. Brain sciences vol 12 issue 9 2022 36138932 biomarker genes discovery of alzheimer's disease by multi-omics-based gene regulatory network construction of microglia. 2022-09-23 2022-09-29 Not clear
Wenliang Gao, Wei Kong, Shuaiqun Wang, Gen Wen, Yaling Y. Biomarker Genes Discovery of Alzheimer's Disease by Multi-Omics-Based Gene Regulatory Network Construction of Microglia. Brain sciences vol 12 issue 9 2022 36138932 microglia, the major immune cells in the brain, mediate neuroinflammation, increased oxidative stress, and impaired neurotransmission in alzheimer's disease (ad), in which most ad risk genes are highly expressed. 2022-09-23 2022-09-29 Not clear
Helena Marcos Pasero, Aurora Garc\\xc3\\xada Tejedor, Juan Antonio Gim\\xc3\\xa9nez-Bastida, Jos\\xc3\\xa9 Mois\\xc3\\xa9s Laparra Llopi. Modifiable Innate Biology within the Gut-Brain Axis for Alzheimer's Disease. Biomedicines vol 10 issue 9 2022 36140198 alzheimer's disease (ad) is a prototypical inflammation-associated loss of cognitive function, with approximately 90% of the ad burden associated with invading myeloid cells controlling the function of the resident microglia. 2022-09-23 2022-09-29 Not clear
Haoran Jia, Tianwu Xi. Tracers progress for positron emission tomography imaging of glial-related disease. Journal of biomedical research vol issue 2022 36131689 extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. 2022-09-22 2022-09-29 Not clear
Na Zhao, Wenhui Qiao, Fuyao Li, Yingxue Ren, Jiaying Zheng, Yuka A Martens, Xusheng Wang, Ling Li, Chia-Chen Liu, Kai Chen, Yiyang Zhu, Tadafumi C Ikezu, Zonghua Li, Axel D Meneses, Yunjung Jin, Joshua A Knight, Yixing Chen, Ligia Bastea, Cynthia Linares, Berkiye Sonustun, Lucy Job, Madeleine L Smith, Manling Xie, Yong U Liu, Anthony D Umpierre, Koichiro Haruwaka, Zachary S Quicksall, Peter Storz, Yan W Asmann, Long-Jun Wu, Guojun B. Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia. The Journal of experimental medicine vol 219 issue 12 2022 36107206 trem2 is exclusively expressed by microglia in the brain and is strongly linked to the risk for alzheimer's disease (ad). 2022-09-16 2022-09-20 Not clear
Ling-Xiao Cao, Wen-Zheng Hu, Wei Dong, Qing Yang, Jin-Hui Yin, Yue Wang, Xin Ni, Yue Huan. Neuropathological report of propionic acidemia. Neuropathology : official journal of the Japanese Society of Neuropathology vol issue 2022 36102083 spongiosis, vacuolization, and the appearance of alzheimer type ii astrocytes and activated microglia were observed as well. 2022-09-14 2022-09-20 Not clear
Jian Jing Siew, Yijuang Chern, Kay-Hooi Khoo, Takashi Angat. Roles of Siglecs in neurodegenerative diseases. Molecular aspects of medicine vol issue 2022 36089405 recent studies have revealed the involvement of microglia in neurodegenerative diseases, such as alzheimer's disease, through the modulation of neuroinflammation. 2022-09-11 2022-09-14 Not clear
Bijay Parajuli, Schuichi Koizum. Strategies for Manipulating Microglia to Determine Their Role in the Healthy and Diseased Brain. Neurochemical research vol issue 2022 36085395 in this article, we review the role of microglia in the normal brain and in various pathological brain conditions, such as alzheimer's disease and multiple sclerosis. 2022-09-10 2022-09-14 Not clear
Qixue Wang, Mengna Lu, Xinyu Zhu, Xinyi Gu, Ting Zhang, Chenyi Xia, Li Yang, Ying Xu, Mingmei Zho. The role of microglia immunometabolism in neurodegeneration: Focus on molecular determinants and metabolic intermediates of metabolic reprogramming. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 153 issue 2022 36076537 this paper provides an overview of the metabolic reprogramming of microglia, the major pathways involved in recent advances in five major neurodegenerative diseases of aging (ndas), including alzheimer's disease (ad), parkinson's disease (pd), multiple sclerosis (ms), amyotrophic lateral sclerosis (als), and frontotemporal dementia (ftd), etc. 2022-09-09 2022-09-14 Not clear
Giulia Di Benedetto, Chiara Burgaletto, Carlo Maria Bellanca, Antonio Munaf\\xc3\\xb2, Renato Bernardini, Giuseppina Cantarell. Role of Microglia and Astrocytes in Alzheimer's Disease: From Neuroinflammation to Ca Cells vol 11 issue 17 2022 36078138 role of microglia and astrocytes in alzheimer's disease: from neuroinflammation to ca alzheimer's disease (ad) is the most common form of dementia worldwide, with a complex, poorly understood pathogenesis. 2022-09-09 2022-09-14 Not clear
Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R Davis, Jered W Wilson, Milica A Margeta, Kristen M Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L Graham, Vivek K Gupta, Keith L Black, Mehdi Mirzaei, Oleg Butovsky, Maya Koronyo-Hamaou. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3 Acta neuropathologica communications vol 10 issue 1 2022 36076283 despite growing interest in studying manifestations of alzheimer's disease (ad) in the retina, a cns organ accessible to noninvasive high-resolution imaging, to date mgnd microglia have not been studied in the ad retina. 2022-09-08 2022-09-14 Not clear
Wei Dai, Ru-Meng Yao, Tian-Yue Mi, Li-Ming Zhang, Hong-Liang Wu, Jin-Bo Cheng, Yun-Feng L. Cognition-enhancing effect of YL-IPA08, a potent ligand for the translocator protein (18\\xe2\\x80\\x89kDa) in the 5\\xe2\\x80\\x89\\xc3\\x97\\xe2\\x80\\x89FAD transgenic mouse model of Alzheimer's pathology. Journal of psychopharmacology (Oxford, England) vol issue 2022 36069168 the change of tspo and the dysfunction of microglia are closely related to the pathogenesis of alzheimer's disease (ad). 2022-09-07 2022-09-14 Not clear
Peng Zhao, Yuanzhong Xu, LuLin Jiang, Xuejun Fan, Leike Li, Xin Li, Hisashi Arase, Yingjun Zhao, Wei Cao, Hui Zheng, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang A. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science translational medicine vol 14 issue 661 2022 36070367 triggering receptor expressed on myeloid cells 2 (trem2) plays crucial roles in alzheimer's disease (ad) by regulating microglia migration toward, and phagocytosis of oligomeric amyloid-\xce\xb2 (oa\xce\xb2) and amyloid plaques. 2022-09-07 2022-09-14 Not clear
Chao Gao, Xin Shen, Yuyan Tan, Shengdi Che. Pathogenesis, therapeutic strategies and biomarker development based on \"omics\" analysis related to microglia in Alzheimer's disease. Journal of neuroinflammation vol 19 issue 1 2022 36058959 pathogenesis, therapeutic strategies and biomarker development based on "omics" analysis related to microglia in alzheimer's disease. 2022-09-04 2022-09-06 Not clear
Boris-Stephan Rauchmann, Matthias Brendel, Nicolai Franzmeier, Lena Trappmann, Mirlind Zaganjori, Ersin Ersoezlue, Estrella Morenas-Rodriguez, Selim Guersel, Lena Burow, Carolin Kurz, Jan Haeckert, Maia Tat\\xc3\\xb2, Julia Utecht, Boris Papazov, Oliver Pogarell, Daniel Janowitz, Katharina Buerger, Michael Ewers, Carla Palleis, Endy Weidinger, Gloria Biechele, Sebastian Schuster, Anika Finze, Florian Eckenweber, Rainer Rupprecht, Axel Rominger, Oliver Goldhardt, Timo Grimmer, Daniel Keeser, Sophia Stoecklein, Olaf Dietrich, Peter Bartenstein, Johannes Levin, G\\xc3\\xbcnter H\\xc3\\xb6glinger, Robert Perneczk. Microglial Activation and Connectivity in Alzheimer Disease and Aging. Annals of neurology vol issue 2022 36053756 alzheimer disease (ad) is characterized by amyloid \xce\xb2 (a\xce\xb2) plaques and neurofibrillary tau tangles, but increasing evidence suggests that neuroinflammation also plays a key role, driven by the activation of microglia. 2022-09-02 2022-09-06 Not clear
Mauro Montalbano, Lajja Majmundar, Urmi Sengupta, Leiana Fung, Rakez Kaye. Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies. Brain pathology (Zurich, Switzerland) vol issue 2022 36054524 pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in alzheimer's disease, progressive supranuclear palsy, and dementia with lewy bodies. 2022-09-02 2022-09-06 Not clear
Shaffi Manchanda, Lorena Galan-Acosta, Axel Abelein, Simone Tambaro, Gefei Chen, Per Nilsson, Jan Johansso. Intravenous treatment with a molecular chaperone designed against \\xce\\xb2-amyloid toxicity improves Alzheimer's disease pathology in mouse models. Molecular therapy : the journal of the American Society of Gene Therapy vol issue 2022 35982621 we find that treatment of a\xce\xb2 precursor protein (app) knockin mice with repeated intravenous injections of rh bri2 brichos r221e, from an age close to the start of development of alzheimer's disease-like pathology, improves recognition and working memory, as assessed using novel object recognition and y maze tests, and reduces a\xce\xb2 plaque deposition and activation of astrocytes and microglia. 2022-08-30 2022-09-06 Not clear
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