| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G K Wilcoc. The temporal lobe in dementia of Alzheimer's type. Gerontology. vol 29. issue 5. 1983-11-23. PMID:6618185. |
the temporal lobe in dementia of alzheimer's type. |
1983-11-23 |
2023-08-12 |
Not clear |
| G K Wilcoc. The temporal lobe in dementia of Alzheimer's type. Gerontology. vol 29. issue 5. 1983-11-23. PMID:6618185. |
evidence is presented of a predilection of neurofibrillary tangle formation and choline acetyltransferase deficiency for the temporal lobe in alzheimer's disease. |
1983-11-23 |
2023-08-12 |
Not clear |
| G K Wilcoc. The temporal lobe in dementia of Alzheimer's type. Gerontology. vol 29. issue 5. 1983-11-23. PMID:6618185. |
together with evidence from studies of cerebral atrophy, 5-ht levels, and clinical findings, this indicates that changes in the temporal lobe may play a prominent role in alzheimer's disease, especially in elderly patients. |
1983-11-23 |
2023-08-12 |
Not clear |
| M J de Leon, A E George, S H Ferris, S Rosenbloom, D R Christman, C I Gentes, B Reisberg, I I Kricheff, A P Wol. Regional correlation of PET and CT in senile dementia of the Alzheimer type. AJNR. American journal of neuroradiology. vol 4. issue 3. 1983-09-20. PMID:6410795. |
these data support previous findings of temporal lobe involvement in alzheimer disease and suggest the involvement of structures in the region of the third ventricle. |
1983-09-20 |
2023-08-12 |
human |
| D M Bowen, S J Allen, J S Benton, M J Goodhardt, E A Haan, A M Palmer, N R Sims, C C Smith, J A Spillane, M M Esiri, D Neary, J S Snowdon, G K Wilcock, A N Daviso. Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease. Journal of neurochemistry. vol 41. issue 1. 1983-08-11. PMID:6306169. |
markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex were examined for changes in alzheimer's disease by use of both neurosurgical and autopsy samples. |
1983-08-11 |
2023-08-12 |
Not clear |
| G K Wilcock, M M Esiri, D M Bowen, C C Smit. Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities. Journal of the neurological sciences. vol 57. issue 2-3. 1983-04-21. PMID:7161627. |
we have examined the choline acetyltransferase [cat] activity in autopsy samples of frontal and temporal lobe cortex from 47 patients (31 with alzheimer's disease, 4 with dementia due to cerebrovascular disease and 12 undemented controls) and compared it with the severity of dementia during life and with the numbers of argyrophilic plaques and neurofibrillary tangles in the corresponding areas of cortex in the contralateral cerebral hemisphere. |
1983-04-21 |
2023-08-12 |
cat |
| G K Wilcock, M M Esiri, D M Bowen, C C Smit. Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities. Journal of the neurological sciences. vol 57. issue 2-3. 1983-04-21. PMID:7161627. |
cat activity was significantly reduced, most severely in the temporal lobe, in patients with alzheimer's disease but not in patients with a cerebrovascular cause for their dementia, and cat activity showed no significant reduction with age in the undemented control patients. |
1983-04-21 |
2023-08-12 |
cat |
| G K Wilcock, M M Esir. Plaques, tangles and dementia. A quantitative study. Journal of the neurological sciences. vol 56. issue 2-3. 1983-02-25. PMID:7175555. |
the temporal lobe cortex and hippocampus were the areas most severely affected by the increased neurofibrillary tangle formation in senile dementia due to alzheimer's disease. |
1983-02-25 |
2023-08-12 |
human |
| K Mitsunobu, H Ishin. Two autopsy cases of Pick's disease with neurofibrillary tangles. Folia psychiatrica et neurologica japonica. vol 36. issue 1. 1982-09-24. PMID:7095671. |
histopathologically, besides pick features--temporal lobe atrophy, fibrillary gliosis of the temporal white matter and neuronal loss in the 2--3 cortical layers--, alzheimer features--neurofibrillary tangles and granulo-vacuolar degeneration--were found in both cases. |
1982-09-24 |
2023-08-12 |
Not clear |
| D M Bowen, A N Daviso. Biochemical changes in the cholinergic system of the ageing brain and in senile dementia. Psychological medicine. vol 10. issue 2. 1980-08-25. PMID:6104344. |
compared with age-matched controls about one third of nerve cell components are lost from the temporal lobe of patients with senile dementia of alzheimer's type. |
1980-08-25 |
2023-08-12 |
human |
| D M Bowen, P White, J A Spillane, M J Goodhardt, G Curzon, P Iwangoff, W Meier-Ruge, A N Daviso. Accelerated ageing or selective neuronal loss as an important cause of dementia? Lancet (London, England). vol 1. issue 8106. 1979-03-24. PMID:83462. |
extensive biochemical analysis of whole temporal lobe from cases of dementia and controls suggests that alzheimer's disease is a primary degenerative nerve-cell disorder and not the result of accelerated ageing. |
1979-03-24 |
2023-08-11 |
Not clear |
| M J Bal. Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study. Acta neuropathologica. vol 37. issue 2. 1977-05-25. PMID:848276. |
the number of pyramidal neurones in the hippocampal cortex was determined in serially sectioned mesial temporal lobe from brains of 18 mentally normal people, as well as those of 8 demented patients with pathologically confirmed alzheimer's disease. |
1977-05-25 |
2023-08-11 |
Not clear |