| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanchita Gupta, Namita Mohindra, Anurag Mehndiratta, Pragya Chaturved. Case 312. Radiology. vol 305. issue 3. 2024-02-15. PMID:38359450. |
she had been taking selective serotonin receptor inhibitors for the past 6 months for a clinical diagnosis of generalized anxiety disorder. |
2024-02-15 |
2024-02-18 |
Not clear |
| Sanchita Gupta, Namita Mohindra, Anurag Mehndiratta, Pragya Chaturved. Case 312: Dercum Disease. Radiology. vol 307. issue 1. 2023-03-27. PMID:36972183. |
she had been taking selective serotonin receptor inhibitors for the past 6 months for a clinical diagnosis of generalized anxiety disorder. |
2023-03-27 |
2023-08-14 |
Not clear |
| Sanchita Gupta, Namita Mohindra, Anurag Mehndiratta, Pragya Chaturved. Case 312. Radiology. vol 305. issue 3. 2022-11-21. PMID:36409617. |
she had been taking selective serotonin receptor inhibitors for the past 6 months for a clinical diagnosis of generalized anxiety disorder. |
2022-11-21 |
2023-08-14 |
Not clear |
| Dyandevi Mathure, Jyotsana R Madan, Kishore N Gujar, Ashok Tupsamundre, Hemant A Ranpise, Kamal Du. Formulation and Evaluation of Niosomal in situ Nasal Gel of a Serotonin Receptor Agonist, Buspirone Hydrochloride for the Brain Delivery via Intranasal Route. Pharmaceutical nanotechnology. vol 6. issue 1. 2019-07-09. PMID:29380709. |
buspirone hydrochloride is an anxiolytic agent and serotonin receptor agonist belonging to azaspirodecanedione class of compounds used in the treatment of anxiety disorders. |
2019-07-09 |
2023-08-13 |
Not clear |
| Susanne Nikolaus, Hans-Wilhelm Müller, Hubertus Hautze. Different patterns of 5-HT receptor and transporter dysfunction in neuropsychiatric disorders--a comparative analysis of in vivo imaging findings. Reviews in the neurosciences. vol 27. issue 1. 2016-10-20. PMID:26376220. |
impairment of serotonin receptor and transporter function is increasingly recognized to play a major role in the pathophysiology of neuropsychiatric diseases including anxiety disorder (ad), major depressive disorder (mdd), bipolar disorder (bd) and schizophrenia (sz). |
2016-10-20 |
2023-08-13 |
Not clear |
| Stéphanie Grégoire, Volker Neugebaue. 5-HT2CR blockade in the amygdala conveys analgesic efficacy to SSRIs in a rat model of arthritis pain. Molecular pain. vol 9. 2015-03-30. PMID:23937887. |
evidence suggests that serotonin receptor subtype 5-ht2cr in the amygdala contributes critically to anxiogenic behavior and anxiety disorders. |
2015-03-30 |
2023-08-12 |
rat |
| Man Luo, Xiang Simon Wang, Bryan L Roth, Alexander Golbraikh, Alexander Tropsh. Application of quantitative structure-activity relationship models of 5-HT1A receptor binding to virtual screening identifies novel and potent 5-HT1A ligands. Journal of chemical information and modeling. vol 54. issue 2. 2014-10-23. PMID:24410373. |
the 5-hydroxytryptamine 1a (5-ht1a) serotonin receptor has been an attractive target for treating mood and anxiety disorders such as schizophrenia. |
2014-10-23 |
2023-08-12 |
Not clear |
| R Hazra, J D Guo, J Dabrowska, D G Rainni. Differential distribution of serotonin receptor subtypes in BNST(ALG) neurons: modulation by unpredictable shock stress. Neuroscience. vol 225. 2013-04-16. PMID:22922122. |
hence, maladaptive changes of 5-ht receptor expression may contribute to stress-induced anxiety disorders. |
2013-04-16 |
2023-08-12 |
Not clear |
| R Hazra, J D Guo, J Dabrowska, D G Rainni. Differential distribution of serotonin receptor subtypes in BNST(ALG) neurons: modulation by unpredictable shock stress. Neuroscience. vol 225. 2013-04-16. PMID:22922122. |
these data suggest that cell type-specific disruption of 5-ht receptor expression in bnst(alg) neurons may contribute to stress-induced anxiety disorders. |
2013-04-16 |
2023-08-12 |
Not clear |
| Ana C Magalhaes, Kevin D Holmes, Lianne B Dale, Laetitia Comps-Agrar, Dennis Lee, Prem N Yadav, Linsay Drysdale, Michael O Poulter, Bryan L Roth, Jean-Philippe Pin, Hymie Anisman, Stephen S G Ferguso. CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature neuroscience. vol 13. issue 5. 2010-05-07. PMID:20383137. |
stress and anxiety disorders are risk factors for depression and these behaviors are modulated by corticotrophin-releasing factor receptor 1 (crfr1) and serotonin receptor (5-ht(2)r). |
2010-05-07 |
2023-08-12 |
mouse |
| Moira Rynn, Sarosh Khalid-Khan, J Felipe Garcia-Espana, Bijan Etemad, Karl Rickel. Early response and 8-week treatment outcome in GAD. Depression and anxiety. vol 23. issue 8. 2007-03-14. PMID:16845651. |
our objective was to compare the predictive value of early response to treatment outcome in patients with generalized anxiety disorder (gad) treated with benzodiazepines, serotonin receptor (5ht-1a) partial agonists, or placebo. |
2007-03-14 |
2023-08-12 |
human |
| Joshua A Gordon, Rene He. The serotonergic system and anxiety. Neuromolecular medicine. vol 5. issue 1. 2004-06-07. PMID:15001810. |
the wide use of serotonin reuptake inhibitors and serotonin receptor agonists in anxiety disorders has suggested a key role for the modulatory neurotransmitter in anxiety. |
2004-06-07 |
2023-08-12 |
mouse |
| Pierre Blier, Nick M War. Is there a role for 5-HT1A agonists in the treatment of depression? Biological psychiatry. vol 53. issue 3. 2003-07-03. PMID:12559651. |
the role of serotonin (5-hydroxytryptamine; 5-ht) in the treatment of depressive and anxiety disorders is underscored by the therapeutic action of selective 5-ht reuptake inhibitors acting to enhance the degree of activation of various 5-ht receptor subtypes. |
2003-07-03 |
2023-08-12 |
human |
| M Alvarez-Guerra, F d'Alché-Birée, W A Wolf, F Vargas, M Dib, R P Gara. 5-HT3- and 5-HT2C-antagonist properties of cyamemazine: significance for its clinical anxiolytic activity. Psychopharmacology. vol 147. issue 4. 2000-03-28. PMID:10672635. |
on the other hand, 5-ht3- and 5-ht2c-receptors have been implicated in anxiety disorders and a previous binding study has shown that cyamemazine possesses high affinity for both serotonin receptor types. |
2000-03-28 |
2023-08-12 |
Not clear |
| I Luck. Serotonin receptor specificity in anxiety disorders. The Journal of clinical psychiatry. vol 57 Suppl 6. 1996-07-19. PMID:8647798. |
serotonin receptor specificity in anxiety disorders. |
1996-07-19 |
2023-08-12 |
Not clear |
| C L Broekkamp, H H Berendsen, F Jenck, A M Van Delf. Animal models for anxiety and response to serotonergic drugs. Psychopathology. vol 22 Suppl 1. 1989-07-03. PMID:2567038. |
in examining anxiety and the response of animal models to serotonergic drugs, four aspects should be taken into account: (1) the serotonin receptor is subdivided into at least six receptor subtypes; (2) benzodiazepines have acute anxiety-relieving effects, whereas antidepressants, serotonin-uptake inhibitors, buspirone, and serotonin antagonists have antianxiety effects only after prolonged administration; (3) diagnostic criteria differentiate several distinguishable anxiety disorders that have different responsiveness to serotonin-related drugs, and (4) various types of animal models exist, each responding differently to serotonin-related drugs. |
1989-07-03 |
2023-08-11 |
Not clear |