Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee, Mario Manto, Akiko Matsunaga, Hidehiro Mizusawa, Kazunori Nanri, Priya Shanmugarajah, Makoto Yoneda, Nobuhiro Yuk. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25823827. |
consensus paper: neuroimmune mechanisms of cerebellar ataxias. |
2016-12-13 |
2023-08-13 |
Not clear |
Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee, Mario Manto, Akiko Matsunaga, Hidehiro Mizusawa, Kazunori Nanri, Priya Shanmugarajah, Makoto Yoneda, Nobuhiro Yuk. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25823827. |
in the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. |
2016-12-13 |
2023-08-13 |
Not clear |
Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee, Mario Manto, Akiko Matsunaga, Hidehiro Mizusawa, Kazunori Nanri, Priya Shanmugarajah, Makoto Yoneda, Nobuhiro Yuk. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25823827. |
in this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. |
2016-12-13 |
2023-08-13 |
Not clear |
Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee, Mario Manto, Akiko Matsunaga, Hidehiro Mizusawa, Kazunori Nanri, Priya Shanmugarajah, Makoto Yoneda, Nobuhiro Yuk. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25823827. |
immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-gad antibodies, the cerebellar type of hashimoto's encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, miller fisher syndrome, ataxia associated with systemic lupus erythematosus, and paraneoplastic cerebellar degeneration. |
2016-12-13 |
2023-08-13 |
Not clear |
Hiroshi Mitoma, Keya Adhikari, Daniel Aeschlimann, Partha Chattopadhyay, Marios Hadjivassiliou, Christiane S Hampe, Jérôme Honnorat, Bastien Joubert, Shinji Kakei, Jongho Lee, Mario Manto, Akiko Matsunaga, Hidehiro Mizusawa, Kazunori Nanri, Priya Shanmugarajah, Makoto Yoneda, Nobuhiro Yuk. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25823827. |
humoral mechanisms, cell-mediated immunity, inflammation, and vascular injuries contribute to the cerebellar deficits in immune-mediated cerebellar ataxias. |
2016-12-13 |
2023-08-13 |
Not clear |
Carlos R Hernandez-Castillo, Victor Galvez, Rosalinda Diaz, Juan Fernandez-Rui. Specific cerebellar and cortical degeneration correlates with ataxia severity in spinocerebellar ataxia type 7. Brain imaging and behavior. vol 10. issue 1. 2016-12-13. PMID:25917872. |
specific cerebellar and cortical degeneration correlates with ataxia severity in spinocerebellar ataxia type 7. |
2016-12-13 |
2023-08-13 |
human |
Hyeeun Shin, Dong-Kyun Lee, Jong-Min Lee, Young-Eun Huh, Jinyoung Youn, Elan D Louis, Jin Whan Ch. Atrophy of the Cerebellar Vermis in Essential Tremor: Segmental Volumetric MRI Analysis. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:26062905. |
cerebellar signs in et patients were assessed using the clinical tremor rating scale and international cooperative ataxia rating scale. |
2016-12-13 |
2023-08-13 |
Not clear |
José Berciano, Kristien Peeters, Antonio García, Tomás López-Alburquerque, Elena Gallardo, Arantxa Hernández-Fabián, Ana L Pelayo-Negro, Els De Vriendt, Jon Infante, Albena Jordanov. NEFL N98S mutation: another cause of dominant intermediate Charcot-Marie-Tooth disease with heterogeneous early-onset phenotype. Journal of neurology. vol 263. issue 2. 2016-12-13. PMID:26645395. |
screening of mutations associated with sca and autosomal recessive cerebellar ataxias was negative. |
2016-12-13 |
2023-08-13 |
Not clear |
Nadja Lindberg Bonne, Lars Evald, Jonas Kjeldbjerg Hanse. A case of the cerebellar cognitive affective syndrome in a 12-year-old boy with acute post-infectious cerebellar ataxia. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 20. issue 3. 2016-12-13. PMID:26818156. |
it is well described in other diseases of the cerebellum such as tumour resection and cerebellar stroke but has not previously been described in detail in paediatric cases of acute post-infectious ataxia (apca). |
2016-12-13 |
2023-08-13 |
Not clear |
Kauzhiro Haginoya, Tomohiro Kaneta, Noriko Togashi, Naomi Hino-Fukuyo, Tomoko Kobayashi, Mitsugu Uematsu, Taro Kitamura, Takehiko Inui, Yukimune Okubo, Yusuke Takezawa, Mai Anzai, Wakaba Endo, Noriko Miyake, Hirotomo Saitsu, Naomichi Matsumoto, Shigeo Kur. FDG-PET study of patients with Leigh syndrome. Journal of the neurological sciences. vol 362. 2016-12-13. PMID:26944169. |
the glucose uptake was decreased significantly in the cerebellum and basal ganglia, which could explain the ataxia and dystonia in patients with leigh syndrome. |
2016-12-13 |
2023-08-13 |
Not clear |
Chunlian Liu, Xue Li, Baisong L. The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment. Aging cell. vol 15. issue 1. 2016-10-28. PMID:26616244. |
here we show that ataxia and cerebellar hypoplasia occur in old mutant mice (> 16 months). |
2016-10-28 |
2023-08-13 |
mouse |
Katharina Feil, Tatiana Bremova, Carolin Muth, Roman Schniepp, Julian Teufel, Michael Strup. Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26519380. |
pharmacological treatment of cerebellar ataxias and cerebellar nystagmus still remains difficult. |
2016-10-21 |
2023-08-13 |
Not clear |
Katharina Feil, Tatiana Bremova, Carolin Muth, Roman Schniepp, Julian Teufel, Michael Strup. Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26519380. |
exceptions are (a) 4-aminopyridine (4-ap) for episodic ataxia type 2 (ea2): one observational and one randomized controlled trial showed a significant effect on the number of attacks of ataxia and quality of life; (b) aminopyridines in cerebellar downbeat nystagmus (dbn): two randomized controlled trials and several observational studies demonstrate a significant improvement of the intensity of dbn, visual acuity, and postural imbalance. |
2016-10-21 |
2023-08-13 |
Not clear |
Andreas Deistung, Maria R Stefanescu, Thomas M Ernst, Marc Schlamann, Mark E Ladd, Jürgen R Reichenbach, Dagmar Timman. Structural and Functional Magnetic Resonance Imaging of the Cerebellum: Considerations for Assessing Cerebellar Ataxias. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26521073. |
structural and functional magnetic resonance imaging of the cerebellum: considerations for assessing cerebellar ataxias. |
2016-10-21 |
2023-08-13 |
Not clear |
Mario Manto, Peter Marië. Cerebellum: from Fundamentals to Translational Approaches. The Seventh International Symposium of the Society for Research on the Cerebellum. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26744149. |
advances in genetics, development, electrophysiology, neuroimaging, neurocognition and affect, as well as in the cerebellar ataxias and the controversies on the roles and functions of the cerebellum were presented. |
2016-10-21 |
2023-08-13 |
Not clear |
Yuji Kaneko, Yuya Tsurutani, Naoko Sagawa, Mai Kondo, Akira Sata, Mariko Miyao, Reo Azuma, Satoshi Orimo, Yuzo Mizun. [A Case of an Elderly Diabetic Patient Developing Wernicke Encephalopathy without Alcohol Abuse or an Unbalanced Diet]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 52. issue 2. 2016-10-17. PMID:25994990. |
he had nystagmus, truncal ataxia and an ocular motility disorder, and the mri study showed increased flair and dwi signals in the peri-third ventricle and periaqueductal region, in addition to the cerebellar vermis. |
2016-10-17 |
2023-08-13 |
Not clear |
Thiago Cardoso Vale, José Luiz Pedroso, Rafaela Almeida Alquéres, Lívia Almeida Dutra, Orlando Graziani Povoas Barsottin. Spontaneous downbeat nystagmus as a clue for the diagnosis of ataxia associated with anti-GAD antibodies. Journal of the neurological sciences. vol 359. issue 1-2. 2016-09-26. PMID:26671081. |
the clinical spectrum of ataxia associated with anti-gad-ab comprises slowly progressive cerebellar ataxia syndrome evolving in months or years, associated with cerebellar atrophy on brain mri. |
2016-09-26 |
2023-08-13 |
human |
Alon Kalron, Lior Fri. The "butterfly diagram": A gait marker for neurological and cerebellar impairment in people with multiple sclerosis. Journal of the neurological sciences. vol 358. issue 1-2. 2016-09-15. PMID:26318202. |
specifically we examined whether the gait butterfly parameters can differentiate between ms patients with normal cerebellar function and those suffering from ataxia. |
2016-09-15 |
2023-08-13 |
human |
Alon Kalron, Lior Fri. The "butterfly diagram": A gait marker for neurological and cerebellar impairment in people with multiple sclerosis. Journal of the neurological sciences. vol 358. issue 1-2. 2016-09-15. PMID:26318202. |
ms participants with ataxia demonstrated higher scores relating to the butterfly gait variability parameters compared to pwms with normal or slightly abnormal cerebellar function. |
2016-09-15 |
2023-08-13 |
human |
Samar S Ayache, Moussa A Chalah, Tarik Al-Ani, Wassim H Farhat, Hela G Zouari, Alain Créange, Jean-Pascal Lefaucheu. Tremor in multiple sclerosis: The intriguing role of the cerebellum. Journal of the neurological sciences. vol 358. issue 1-2. 2016-09-15. PMID:26421829. |
patients with visible tremor had more severe score of ataxia and clinical signs of cerebellar dysfunction, as well as a more reduced ctci on neurophysiological investigation. |
2016-09-15 |
2023-08-13 |
Not clear |